Genomic Analysis of hESC Pedigrees Identifies De Novo Mutations and Enables Determination of the Timing and Origin of Mutational Events

Cell Reports

Volumn 4, Issue 6, 2013, Pages 1288-1302

  Ben Yosef, Dalit ^a,b   Boscolo, Francesca S ^c,d   Amir, Hadar ^a,c   Malcov, Mira ^a   Amit, Ami ^a   Laurent, Louise C ^c,d  

^a LIS MATERNITY HOSPITAL   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLASTOCYST; BLASTOMA; CHROMOSOME 17; CHROMOSOME ABERRATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE DELETION; GENE DUPLICATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENOTYPE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PEDIGREE ANALYSIS; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SHORT TANDEM REPEAT; SINGLE NUCLEOTIDE POLYMORPHISM;

CELL GROWTH PROCESSES; CELL LINE; EMBRYONIC STEM CELLS; GENOMICS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MUTATION; PEDIGREE; PLURIPOTENT STEM CELLS;

EID: 84884593771     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.08.009     Document Type: Article

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