Genetic stability of human embryonic stem cells: A first-step toward the development of potential hESC-based systems for modeling childhood leukemia

Leukemia Research

Volumn 33, Issue 7, 2009, Pages 980-990

  Catalina, P ^a   Bueno, C ^a   Montes, R ^a   Nieto, A ^a   Ligero, G ^a   Sanchez, L ^a   Jara, M ^b   Rasillo, A ^b   Orfao, A ^b   Cigudosa, J ^c   Hovatta, O ^d   Greaves, M ^e   Menendez, P ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b Centro de Investigacion del Cancer   (Spain)

^c Centro Nacional de Investigaciones Oncológicas   (Spain)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Disease modeling; Genomic stability; hESCs; Infant childhood leukemia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHILDHOOD LEUKEMIA; CLONOGENESIS; CONTROLLED STUDY; CYTOGENETICS; EMBRYO; EMBRYONIC STEM CELL; GENETIC STABILITY; GENOMIC INSTABILITY; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEDICAL RESEARCH; MOLECULAR GENETICS; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; STRUCTURAL CHROMOSOME ABERRATION;

ACUTE DISEASE; ADULT; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CHILD; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; FMS-LIKE TYROSINE KINASE 3; GENOMIC INSTABILITY; HUMANS; IMMUNOENZYME TECHNIQUES; KARYOTYPING; LEUKEMIA; MALE; MICE; MICE, SCID; MUTATION; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENE PROTEINS C-KIT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTRAL KARYOTYPING;

EID: 67349140909     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.08.028     Document Type: Article

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