A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD rats

Nutrition Research

Volumn 33, Issue 10, 2013, Pages 849-858

  Liu, Han Qiang ^a   Qiu, Ya ^a   Mu, Ying ^b   Zhang, Xian Jiao ^c   Liu, Lu ^a   Hou, Xiang Hong ^a   Zhang, Lei ^a   Xu, Xiao Na ^a   Ji, Ai Ling ^a   Cao, Rui ^a   Yang, Rui Hua ^a   Wang, Feng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b 302 MILITARY HOSPITAL   (China)

^c SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Insulin resistance; Polyunsaturated fatty acids; Pro inflammatory cytokines; Rat; Toll like receptor 4

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; GLUCOSE; INSULIN; INTERLEUKIN 6; MESSENGER RNA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; SATURATED FATTY ACID; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOWN REGULATION; FAT INTAKE; GENE CONTROL; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; INTRAABDOMINAL FAT; MALE; METABOLIC DISORDER; NONHUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TRIACYLGLYCEROL BLOOD LEVEL;

RATTUS;

C-REACTIVE PROTEIN; CRP; DHA; DOCOSAHEXANOIC ACID; EICOSAPENTAENOIC ACID; EPA; H&E; HEMATOXYLIN AND EOSIN; HOMA-IR; HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE; IKK-Β; IL-6; INSULIN RECEPTOR SUBSTRATE; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; INTERLEUKIN-6; IR; IRS; ITT; IΚB KINASE Β; LIPOPOLYSACCHARIDE; LPS; MYD88; MYELOID DIFFERENTIATION FACTOR-88; NF-ΚB; NUCLEAR FACTOR ΚB; PCR; POLYMERASE CHAIN REACTION; POLYUNSATURATED FATTY ACIDS; PRO-INFLAMMATORY CYTOKINES; PUFAS; RAT; SATURATED FATTY ACID; SFA; T2DM; TC; TG; TIR DOMAIN-CONTAINING ADAPTOR INDUCING INTERFERON Β; TLR; TNF-Α; TOLL-LIKE RECEPTOR; TOLL-LIKE RECEPTOR-4; TOTAL CHOLESTEROL; TRAM; TRIF; TRIF-RELATED ADAPTOR MOLECULE; TRIGLYCERIDES; TUMOR NECROSIS FACTOR Α; TYPE 2 DIABETES MELLITUS;

ANIMALS; C-REACTIVE PROTEIN; DIETARY FATS; DOWN-REGULATION; FATTY ACIDS; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; GLUCOSE INTOLERANCE; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-6; INTRA-ABDOMINAL FAT; LIPIDS; MALE; OBESITY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; WEIGHT LOSS;

EID: 84884593409     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2013.07.004     Document Type: Article

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