Reactive oxygen species produced by NADPH oxidase and mitochondrial dysfunction in lung after an acute exposure to Residual Oil Fly Ashes

Toxicology and Applied Pharmacology

Volumn 270, Issue 1, 2013, Pages 31-38

  Magnani, Natalia D ^a   Marchini, Timoteo ^a   Vanasco, Virginia ^a   Tasat, Deborah R ^b   Alvarez, Silvia ^a   Evelson, Pablo ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

Author keywords

Air pollution; Lung; Mitochondria; NADPH oxidase; Reactive O2 species; Residual oil fly ash (ROFA)

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AIR POLLUTANT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVITY; EXPOSURE; LUNG INJURY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PARTICULATE MATTER; QUANTITATIVE STUDY; RESIDUAL OIL FLY ASH; RESPIRATORY CHAIN;

ADMINISTRATION, INTRANASAL; ANIMALS; COAL ASH; ENVIRONMENTAL POLLUTANTS; FEMALE; LUNG; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; NADPH OXIDASE; REACTIVE OXYGEN SPECIES;

EID: 84877115584     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.04.002     Document Type: Article

References (49)

1. Aguilera-Aguirre L., Bacsi A., Saavedra-Molina A., Kurosky A., Sur S., Boldogh I. Mitochondrial dysfunction increases allergic airway inflammation. J. Immunol. 2009, 183:5379-5387.
2. + channels as redox signals to liver mitochondria in response to hypertriglyceridemia. Free Radic. Biol. Med. 2009, 47:1432-1439.
3. Andreyev A.Y., Kushnareva K.E., Starkov A.A. Mitochondrial metabolism of reactive oxygen species. Biochemistry 2005, 70:200-214.
4. Arantes-Costa F., Lopes F., Toledo A., Magliarelli-Filho P., Moriya H., Carvalho-Oliveira R., Mauad T., Saldiva P.H., Martins M. Effects of Residual Oil Fly Ash (ROFA) in mice with chronic allergic pulmonary inflammation. Toxicol. Pathol. 2008, 36:680-686.
5. Becker S., Soukup J.M., Gallagher J.E. Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages. Toxicol. In Vitro 2002, 16:209-218.
6. Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 2007, 87:245-313.
7. Boveris A. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. Methods Enzymol. 1984, 105:429-435.
8. Boveris D.L., Boveris A. Oxygen delivery to tissues and mitochondrial respiration. Front. Biosci. 2007, 12:1014-1023.
9. Boveris A., Costa L., Cadenas E., Poderoso J. Regulation of mitochondrial respiration by adenosine diphosphate, oxygen and nitric oxide synthase. Methods Enzymol. 1999, 301:188-198.
10. Brand M.D., Nicholls D.G. Assessing mitochondrial dysfunction in cells. Biochem. J. 2011, 435:297-312.
11. Cadenas E., Boveris A. Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria. Biochem. J. 1980, 188:31-37.
12. Cardoso A.R., Queliconi B.B., Kowaltowski A.J. Mitochondrial ion transport pathways: role in metabolic diseases. Biochim. Biophys. Acta 2010, 1797:832-838.
13. Chen L.C., Lippmann M. Effects of metal within ambient air particulate matter (PM) on human health. Inhal. Toxicol. 2009, 21:1-31.
14. Costa D.L., Dreher K.L. Bioavailable transition metals in particulate matter mediate cardiopulmonary injury in healthy and compromised animal models. Environ. Health Perspect. 1997, 105:1053-1060.
15. Czerniczyniec A., Karadayian A.G., Bustamante J., Cutrera R.A., Lores-Arnaiz S. Paraquat induces behavioral changes and cortical and striatal mitochondrial dysfunction. Free Radic. Biol. Med. 2011, 51:1428-1436.
16. 10) exposure in lung mitochondria. Toxicol. Pathol 2012, 10.1177/01926623312463784.
17. Di Pietro A., Visalli G., Baluce B., Micale R.T., La Maestra S., Spataro P., De Flora S. Multigenerational mitochondrial alterations in pneumocytes exposed to oil fly ash metals. Int. J. Hyg. Environ. Health 2011, 214:138-144.
18. Dominici F., Peng L., Bell M., Pham L., McDermott A., Zeger S., Samet J. Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA 2006, 295:1127-1134.
19. Drew B., Leeuwenburgh C. Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 285:1259-1267.
20. Evelson P., Travacio M., Repetto M., Escobar J., Llesuy S., Lissi E. Evaluation of total reactive antioxidant potential (TRAP) of tissue homogenates and their cytosols. Arch. Biochem. Biophys. 2001, 388:261-266.
21. Ghio A., Silbajoris R., Carson J., Samet J. Biologic effects of oil fly ash. Environ. Health Perspect. 2002, 110:89-94.
22. Goldsmith C.A., Imrich A., Danaee H., Ning Y.Y., Kobzik L. Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. J. Toxicol. Environ. Health A 1998, 54:529-545.
23. Killingsworth C.K., Alessandrini F., Krishna Murty G.C., Catalano P.J., Paulauskis J.D., Godleski J.J. Inflammation, chemokine expression, and death in monocrotaline-treated rats following fuel coal ash inhalation. Inhal. Toxicol. 1997, 9:541-545.
24. Kowaltowski A.J., de Souza-Pinto N.C., Castilho R.F., Vercesi A.E. Mitochondria and reactive oxygen species. Free Radic. Biol. Med. 2009, 47:333-343.
25. Levine R.L., Williams J.A., Stadtman R.E., Shacter E. Carbonyl assays for determination of oxidatively modified proteins. Methods Enzymol. 1994, 233:346-357.
26. Li N., Xia T., Nel A.E. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic. Biol. Med. 2008, 44:1689-1699.
27. Lowry O., Rosebrough A., Farr A., Randall R. Protein measurement with the phenol reagent. J. Biol. Chem. 1951, 193:265-275.
28. Magnani N.D., Marchini T., Tasat D.R., Alvarez S., Evelson P. Lung oxidative metabolism after exposure to ambient particles. Biochem. Biophys. Res. Commun. 2011, 412:667-672.
29. Mailloux R.J., Harper M.-E. Uncoupling proteins and the control of mitochondrial reactive oxygen species production. Free Radic. Biol. Med. 2011, 51:1106-1115.
30. Marchini T., Magnani N.D., D'Annunzio V., Tasat D.R., Gelpi R.J., Alvarez S., Evelson P. Impaired cardiac mitochondrial function and contractile reserve following an acute exposure to environmental particulate matter. Biochim. Biophys. Acta 2012, 1830(3):2545-2552.
31. Martin S., Dawidowski L., Mandalunis P., Cereceda-Balic F., Tasat D.R. Characterization and biological effect of Buenos Aires urban air particles on mice lungs. Environ. Res. 2007, 105:340-349.
32. Mela L., Seitz S. Isolation of mitochondria with emphasis on heart mitochondria from small amounts of tissue. Methods Enzymol. 1979, 55:39-46.
33. Nel A.E. Atmosphere. Air pollution-related illness: effects of particles. Science 2005, 308:804-806.
34. Ostachuk O., Evelson P., Martin S., Dawidowski L., Yakisich S., Tasat D. Age-related lung cell response to urban Buenos Aires air particle soluble fraction. Environ. Res. 2008, 107:170-177.
35. Poderoso J., Fernandez S., Carreras M.C., Tchercanski D., Acevedo C., Rubio M., Peralta J., Boveris A. Liver oxygen uptake dependence and mitochondrial function in septic rats. Circ. Shock 1994, 44:175-182.
36. Pope C.A. Epidemiology of fine particle air pollution and human health: biologic mechanism and who's at risk?. Environ. Health Perspect. 2000, 108:713-723.
37. 2 and systolic blood pressure in mice. Circ. Res. 2001, 89:408-414.
38. Southam D.S., Dolovich M., O'Byrne P.M., Inman M.D. Distribution of intranasal instillations in mice: effects of volume, time, body position, and anaesthesia. Am. J. Physiol. Lung Cell. Mol. Physiol. 2002, 282:833-839.
39. Upadhyay D., Panduri V., Ghio A., Kamp D.W. Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria. Am. J. Respir. Cell Mol. Biol. 2003, 29:180-187.
40. Valdez L.B., Zaobornyj T., Bombicino S., Iglesias D.E., Boveris A., Donato M., D'Annunzio V., Buchholz B., Gelpi R.J. Complex I syndrome in myocardial stunning and the effect of adenosine. Free Radic. Biol. Med. 2011, 15:1203-1212.
41. van der Vliet A. NADPH oxidases in lung biology and pathology: host defences enzymes and more. Free Radic. Biol. Med. 2008, 44:938-955.
42. van der Vliet A. Nox enzymes in allergic airway inflammation. Biochim. Biophys. Acta 2011, 1810:1035-1044.
43. Vanasco V., Cimolai M.C., Evelson P., Alvarez S. The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by α-lipoic acid. Free Radic. Res. 2008, 42:8.
44. Vanasco V., Magnani N.D., Cimolai M.C., Valdez L.B., Evelson P., Boveris A., Alvarez S. Endotoxemia impairs heart mitochondrial function by decreasing electron transfer, ATP synthesis and ATP content without affecting membrane potential. J. Bioenerg. Biomembr. 2012, 44:243-252.
45. Vaquero E.C., Edderkaoui M., Pandol S.J., Gukovsky I., Gukovskaya A.S. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J. Biol. Chem. 2004, 279:34643-34654.
46. Wei Y., Sower J., Nistala R., Gong H., Uptergrove G.M., Clark S.E., Morris M.E., Szary N., Manrique C., Stump C. Angiotensin II-induced NADPH oxidase impairs insulin signaling in skeletal muscle cells. J. Biol. Chem. 2006, 281:35137-35146.
47. Xia T., Kovochich M., Nel A.E. Impairment of mitochondrial function by particulate matter (PM) and their toxic components: implications for PM-induced cardiovascular and lung disease. Front. Biosci. 2007, 12:1238-1246.
48. Yagi K. A simple fluorometric assay lipoperoxide in blood plasma. Biochem. Med. 1976, 15:212-216.
49. Yonetani T. Cytochrome oxidase: beef heart. Methods Enzymol. 1967, 10:332-335.