Role of one-carbon metabolizing pathway genes and gene-nutrient interaction in the risk of non-Hodgkin lymphoma

Cancer Causes and Control

Volumn 24, Issue 10, 2013, Pages 1875-1884

  Li, Qian ^a,b   Lan, Qing ^c   Zhang, Yawei ^a   Bassig, Bryan A ^a   Holford, Theodore R ^a   Leaderer, Brian ^a   Boyle, Peter ^d   Zhu, Yong ^a   Qin, Qin ^e   Chanock, Stephen ^c   Rothman, Nathaniel ^c   Zheng, Tongzhang ^a  

^a YALE UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d INTERNATIONAL PREVENTION RESEARCH INSTITUTE   (France)

^e UNIVERSITY OF SOUTHERN MAINE   (United States)

Author keywords

Cancer; Dietary nutrients; Folate; Non Hodgkin lymphoma; One carbon metabolizing genes

Indexed keywords

ADENINE; CYTOSINE; FOLIC ACID; GUANINE; METHIONINE; METHYL CPG BINDING PROTEIN 2; PYRIDOXINE; THYMINE;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER PATIENT; CANCER RISK; CBS GENE; CONTROLLED STUDY; DIETARY INTAKE; DNA POLYMORPHISM; FEMALE; FTHFD GENE; GENE; GENE INTERACTION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MBD2 GENE; NONHODGKIN LYMPHOMA; NUTRIENT; ONE CARBON METABOLISM GENE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROTEIN INTAKE; RISK ASSESSMENT; RISK REDUCTION; SHMT1 GENE; UNITED STATES; VITAMIN INTAKE;

ADULT; AGED; AGED, 80 AND OVER; CARBON; CASE-CONTROL STUDIES; CONNECTICUT; FEMALE; GENOTYPE; HUMANS; LYMPHOMA, NON-HODGKIN; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; YOUNG ADULT;

EID: 84884587528     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-013-0264-3     Document Type: Article

References (45)

1. Nauss KM, Newberne PM (1981) Effects of dietary folate, vitamin B12 and methionine/choline deficiency on immune function. Adv Exp Med Biol 135:63-91
2. Zheng T, Mayne ST, Boyle P, Holford TR, Liu WL, Flannery J (1992) Epidemiology of non-Hodgkin lymphoma in Connecticut. 1935-1988. Cancer 70:840-849
3. Bassig BA, Lan Q, Rothman N, Zhang Y, Zheng T (2012) Current understanding of lifestyle and environmental factors and risk of non-Hodgkin lymphoma: an epidemiological update. J Cancer Epidemiol 2012:978930
4. Kuppers R (2005) Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer 5:251-262
5. Rossi D, Capello D, Gloghini A et al (2004) Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia. Haematologica 89:154-164
6. Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC (1993) bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82:1820-1828
7. Matsuo K, Suzuki R, Hamajima N et al (2001) Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma. Blood 97:3205-3209
8. Robien K, Ulrich CM (2003) 5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview. Am J Epidemiol 157:571-582
9. Skibola CF, Curry JD, Nieters A (2007) Genetic susceptibility to lymphoma. Haematologica 92:960-969
10. Lim U, Wang SS, Hartge P et al (2007) Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study. Blood 109:3050-3059
11. Linnebank M, Schmidt S, Kolsch H et al (2004) The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma. Br J Cancer 90:1969-1971
12. Lincz LF, Scorgie FE, Kerridge I, Potts R, Spencer A, Enno A (2003) Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non-Hodgkin's lymphoma or multiple myeloma. Br J Haematol 120:1051-1054
13. Niclot S, Pruvot Q, Besson C et al (2006) Implication of the folate-methionine metabolism pathways in susceptibility to follicular lymphomas. Blood 108:278-285
14. Hishida A, Matsuo K, Hamajima N et al (2003) Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma. Haematologica 88:159-166
15. Skibola CF, Smith MT, Hubbard A et al (2002) Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 99:3786-3791
16. Lightfoot TJ, Skibola CF, Willett EV et al (2005) Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes. Cancer Epidemiol Biomarkers Prev 14:2999-3003
17. Lee KM, Lan Q, Kricker A et al (2007) One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia. Hum Genet 122:525-533
18. Skibola CF, Forrest MS, Coppede F et al (2004) Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma. Blood 104:2155-2162
19. Skibola CF, Smith MT, Kane E et al (1999) Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci USA 96:12810-12815
20. Matsuo K, Hamajima N, Suzuki R et al (2004) Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma. Am J Hematol 77:351-357
21. Gemmati D, Ongaro A, Scapoli GL et al (2004) Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults. Cancer Epidemiol Biomarkers Prev 13:787-794
22. Chang ET, Balter KM, Torrang A et al (2006) Nutrient intake and risk of non-Hodgkin's lymphoma. Am J Epidemiol 164:1222-1232
23. Koutros S, Zhang Y, Zhu Y et al (2008) Nutrients contributing to one-carbon metabolism and risk of non-Hodgkin lymphoma subtypes. Am J Epidemiol 167:287-294
24. Lim U, Schenk M, Kelemen LE et al (2005) Dietary determinants of one-carbon metabolism and the risk of non-Hodgkin's lymphoma: NCI-SEER case-control study, 1998-2000. Am J Epidemiol 162:953-964
25. Polesel J, Talamini R, Montella M et al (2006) Linoleic acid, vitamin D and other nutrient intakes in the risk of non-Hodgkin lymphoma: an Italian case-control study. Ann Oncol 17:713-718
26. Zheng T, Holford TR, Leaderer B et al (2004) Diet and nutrient intakes and risk of non-Hodgkin's lymphoma in Connecticut women. Am J Epidemiol 159:454-466
27. Lan Q, Zheng T, Chanock S et al (2007) Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma. Carcinogenesis 28:823-827
28. Zhang Y, Lan Q, Rothman N et al (2005) A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma. J Natl Cancer Inst 97:1616-1618
29. Willett WC (1998) Nutritional epidemiology, 2nd edn. Oxford University Press, New York
30. (2007) University of Minnesota Nutrition Coordinating Center. NDSR, University of Minnesota Nutrition Coordinating Center, Minneapolis, MN
31. Frosst P, Blom HJ, Milos R et al (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113
32. van der Put NM, Gabreels F, Stevens EM et al (1998) A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62:1044-1051
33. Kawakami K, Salonga D, Park JM et al (2001) Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression. Clin Cancer Res 7:4096-4101
34. Lim U, Peng K, Shane B et al (2005) Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr 135:1989-1994
35. Choi SW, Mason JB (2000) Folate and carcinogenesis: an integrated scheme. J Nutr 130:129-132
36. Metayer C, Scelo G, Chokkalingam AP et al (2011) Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control CCC 22:1243-1258
37. Hendrich B, Abbott C, McQueen H, Chambers D, Cross S, Bird A (1999) Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes. Mamm Genome 10:906-912
38. Ng HH, Zhang Y, Hendrich B et al (1999) MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat Genet 23:58-61
39. Reuland SN, Vlasov AP, Krupenko SA (2006) Modular organization of FDH: exploring the basis of hydrolase catalysis. Protein Sci 15:1076-1084
40. Krupenko SA, Oleinik NV (2002) 10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells. Cell Growth Differ 13:227-236
41. Krajinovic M, Lamothe S, Labuda D et al (2004) Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia. Blood 103:252-257
42. Corella D, Ordovas JM (2005) Single nucleotide polymorphisms that influence lipid metabolism: interaction with dietary factors. Annu Rev Nutr 25:341-390
43. Garcia-Closas M, Thompson WD, Robins JM (1998) Differential misclassification and the assessment of gene-environment interactions in case-control studies. Am J Epidemiol 147:426-433
44. Garcia-Closas M, Rothman N, Lubin J (1999) Misclassification in case-control studies of gene-environment interactions: assessment of bias and sample size. Cancer Epidemiol Biomark Prev 8:1043-1050
45. Morton LM, Wang SS, Cozen W et al (2008) Etiologic heterogeneity among non-Hodgkin lymphoma subtypes. Blood 112:5150-5160