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Volumn 4 AUG, Issue , 2013, Pages

Immune infiltrates as predictive markers of survival in pancreatic cancer patients

Author keywords

Macrophages; Mast cells; Pancreatic cancer; Survival predictive factor; Tumor infiltrating lymphocytes; Univariate and multivariate analyses

Indexed keywords

CANCER GRADING; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; DISEASE FREE SURVIVAL; HUMAN; MACROPHAGE; MAST CELL; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PANCREAS CANCER; SHORT SURVEY; SURVIVAL PREDICTION; TH1 CELL; TH2 CELL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT;

EID: 84884583506     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00210     Document Type: Short Survey
Times cited : (77)

References (56)
  • 1
    • 0031961278 scopus 로고    scopus 로고
    • Effector T lymphocyte subsets in human pancreatic cancer: detection of CD8+CD18+ cells and CD8+CD103+ cells by multi-epitope imaging
    • doi: 10.1046/j.1365-2249.1998.00546.x
    • Ademmer, K., Ebert, M., Muller-Ostermeyer, F., Friess, H., Buchler, M. W., Schubert, W., et al. (1998). Effector T lymphocyte subsets in human pancreatic cancer: detection of CD8+CD18+ cells and CD8+CD103+ cells by multi-epitope imaging. Clin. Exp. Immunol. 112, 21-26. doi: 10.1046/j.1365-2249.1998.00546.x
    • (1998) Clin. Exp. Immunol , vol.112 , pp. 21-26
    • Ademmer, K.1    Ebert, M.2    Muller-Ostermeyer, F.3    Friess, H.4    Buchler, M.W.5    Schubert, W.6
  • 2
    • 84857141296 scopus 로고    scopus 로고
    • Cancer-related inflammation: common themes and therapeutic opportunities
    • doi: 10.1016/j.semcancer.2011.12.005
    • Balkwill, F. R., and Mantovani, A. (2012). Cancer-related inflammation: common themes and therapeutic opportunities. Semin. Cancer Biol. 22, 33-40. doi: 10.1016/j.semcancer.2011.12.005
    • (2012) Semin. Cancer Biol. , vol.22 , pp. 33-40
    • Balkwill, F.R.1    Mantovani, A.2
  • 3
    • 79953154967 scopus 로고    scopus 로고
    • CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
    • doi: 10.1126/science.1198443
    • Beatty, G. L., Chiorean, E. G., Fishman, M. P., Saboury, B., Teitelbaum, U. R., Sun, W., et al. (2011). CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 331, 1612-1616. doi: 10.1126/science.1198443
    • (2011) Science , vol.331 , pp. 1612-1616
    • Beatty, G.L.1    Chiorean, E.G.2    Fishman, M.P.3    Saboury, B.4    Teitelbaum, U.R.5    Sun, W.6
  • 4
    • 79952709160 scopus 로고    scopus 로고
    • Prognostic significance of mast cell count following curative resection for pancreatic ductal adenocarcinoma
    • doi: 10.1016/j.surg.2010.10.009
    • Cai, S. W., Yang, S. Z., Gao, J., Pan, K., Chen, J. Y., Wang, Y. L., et al. (2011). Prognostic significance of mast cell count following curative resection for pancreatic ductal adenocarcinoma. Surgery 149, 576-584. doi: 10.1016/j.surg.2010.10.009
    • (2011) Surgery , vol.149 , pp. 576-584
    • Cai, S.W.1    Yang, S.Z.2    Gao, J.3    Pan, K.4    Chen, J.Y.5    Wang, Y.L.6
  • 5
    • 81255138309 scopus 로고    scopus 로고
    • Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma
    • doi: 10.1158/1078-0432.CCR-11-0607
    • Chang, D. Z., Ma, Y., Ji, B., Wang, H., Deng, D., Liu, Y., et al. (2011). Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma. Clin. Cancer Res. 17, 7015-7023. doi: 10.1158/1078-0432.CCR-11-0607
    • (2011) Clin. Cancer Res. , vol.17 , pp. 7015-7023
    • Chang, D.Z.1    Ma, Y.2    Ji, B.3    Wang, H.4    Deng, D.5    Liu, Y.6
  • 6
    • 67349181841 scopus 로고    scopus 로고
    • Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer
    • doi: 10.1016/j.canlet.2008.09.037
    • Clark, C. E., Beatty, G. L., and Vonderheide, R. H. (2009). Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer. Cancer Lett. 279, 1-7. doi: 10.1016/j.canlet.2008.09.037
    • (2009) Cancer Lett , vol.279 , pp. 1-7
    • Clark, C.E.1    Beatty, G.L.2    Vonderheide, R.H.3
  • 7
    • 79952724783 scopus 로고    scopus 로고
    • Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
    • doi: 10.1084/jem.20101876
    • De Monte, L., Reni, M., Tassi, E., Clavenna, D., Papa, I., Recalde, H., et al. (2011). Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J. Exp. Med. 208, 469-478. doi: 10.1084/jem.20101876
    • (2011) J. Exp. Med. , vol.208 , pp. 469-478
    • De Monte, L.1    Reni, M.2    Tassi, E.3    Clavenna, D.4    Papa, I.5    Recalde, H.6
  • 8
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • doi: 10.1200/JCO.2009.23.7370
    • Denkert, C., Loibl, S., Noske, A., Roller, M., Muller, B. M., Komor, M., et al. (2010). Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J. Clin. Oncol. 28, 105-113. doi: 10.1200/JCO.2009.23.7370
    • (2010) J. Clin. Oncol. , vol.28 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3    Roller, M.4    Muller, B.M.5    Komor, M.6
  • 9
    • 2542430341 scopus 로고    scopus 로고
    • The three Es of cancer immunoediting. Annu
    • doi: 10.1146/annurev.immunol.22.012703.104803
    • Dunn, G. P., Old, L. J., and Schreiber, R. D. (2004). The three Es of cancer immunoediting. Annu. Rev. Immunol. 22, 329-360. doi: 10.1146/annurev.immunol.22.012703.104803
    • (2004) Rev. Immunol. , vol.22 , pp. 329-360
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 11
    • 0036849231 scopus 로고    scopus 로고
    • The stem cell factor-c-kit system and mast cells in human pancreatic cancer
    • Esposito, I., Kleeff, J., Bischoff, S. C., Fischer, L., Collecchi, P., Iorio, M., et al. (2002). The stem cell factor-c-kit system and mast cells in human pancreatic cancer. Lab. Invest. 82, 1481-1492.
    • (2002) Lab. Invest. , vol.82 , pp. 1481-1492
    • Esposito, I.1    Kleeff, J.2    Bischoff, S.C.3    Fischer, L.4    Collecchi, P.5    Iorio, M.6
  • 12
    • 2642547301 scopus 로고    scopus 로고
    • Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma
    • doi: 10.1136/jcp.2003.014498
    • Esposito, I., Menicagli, M., Funel, N., Bergmann, F., Boggi, U., Mosca, F., et al. (2004). Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma. J. Clin. Pathol. 57, 630-636. doi: 10.1136/jcp.2003.014498
    • (2004) J. Clin. Pathol. , vol.57 , pp. 630-636
    • Esposito, I.1    Menicagli, M.2    Funel, N.3    Bergmann, F.4    Boggi, U.5    Mosca, F.6
  • 13
    • 84866450512 scopus 로고    scopus 로고
    • The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion. Front
    • doi: 10.3389/fphys.2012.00270
    • Evans, A., and Costello, E. (2012). The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion. Front. Physiol. 3:270. doi: 10.3389/fphys.2012.00270
    • (2012) Physiol , vol.3 , pp. 270
    • Evans, A.1    Costello, E.2
  • 14
    • 80052206084 scopus 로고    scopus 로고
    • Prognostic and predictive impact of intra- and peritumoral immune infiltrates
    • doi: 10.1158/0008-5472.CAN-11-1316
    • Fridman, W. H., Galon, J., Pages, F., Tartour, E., Sautes-Fridman, C., and Kroemer, G. (2011). Prognostic and predictive impact of intra- and peritumoral immune infiltrates. Cancer Res. 71, 5601-5605. doi: 10.1158/0008-5472.CAN-11-1316
    • (2011) Cancer Res , vol.71 , pp. 5601-5605
    • Fridman, W.H.1    Galon, J.2    Pages, F.3    Tartour, E.4    Sautes-Fridman, C.5    Kroemer, G.6
  • 15
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • doi: 10.1038/nrc3245
    • Fridman, W. H., Pages, F., Sautes-Fridman, C., and Galon, J. (2012). The immune contexture in human tumours: impact on clinical outcome. Nat. Rev. Cancer 12, 298-306. doi: 10.1038/nrc3245
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 16
    • 1842505346 scopus 로고    scopus 로고
    • CD8+ tumor-infiltrating lymphocytes together with CD4+ tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma
    • doi: 10.1097/00006676-200401000-00023
    • Fukunaga, A., Miyamoto, M., Cho, Y., Murakami, S., Kawarada, Y., Oshikiri, T., et al. (2004). CD8+ tumor-infiltrating lymphocytes together with CD4+ tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma. Pancreas 28, e26-e31. doi: 10.1097/00006676-200401000-00023
    • (2004) Pancreas , vol.28
    • Fukunaga, A.1    Miyamoto, M.2    Cho, Y.3    Murakami, S.4    Kawarada, Y.5    Oshikiri, T.6
  • 17
    • 44349101991 scopus 로고    scopus 로고
    • Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
    • doi: 10.1038/nri2327
    • Galli, S. J., Grimbaldeston, M., and Tsai, M. (2008). Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8, 478-486. doi: 10.1038/nri2327
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 478-486
    • Galli, S.J.1    Grimbaldeston, M.2    Tsai, M.3
  • 18
    • 13944249962 scopus 로고    scopus 로고
    • Mast cells in the development of adaptive immune responses
    • doi: 10.1038/ni1158
    • Galli, S. J., Nakae, S., and Tsai, M. (2005). Mast cells in the development of adaptive immune responses. Nat. Immunol. 6, 135-142. doi: 10.1038/ni1158
    • (2005) Nat. Immunol. , vol.6 , pp. 135-142
    • Galli, S.J.1    Nakae, S.2    Tsai, M.3
  • 19
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • doi: 10.1126/science.1129139
    • Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pages, C., et al. (2006). Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313, 1960-1964. doi: 10.1126/science.1129139
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6
  • 20
    • 84866852663 scopus 로고    scopus 로고
    • Cancer classification using the Immunoscore: a worldwide task force
    • doi: 10.1186/1479-5876-10-205
    • Galon, J., Pages, F., Marincola, F. M., Angell, H. K., Thurin, M., Lugli, A., et al. (2012). Cancer classification using the Immunoscore: a worldwide task force. J. Transl. Med. 10, 205. doi: 10.1186/1479-5876-10-205
    • (2012) J. Transl. Med. , vol.10 , pp. 205
    • Galon, J.1    Pages, F.2    Marincola, F.M.3    Angell, H.K.4    Thurin, M.5    Lugli, A.6
  • 21
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • doi: 10.1038/nri978
    • Gordon, S. (2003). Alternative activation of macrophages. Nat. Rev. Immunol. 3, 23-35. doi: 10.1038/nri978
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 22
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: functions of cells recruited to the tumor microenvironment
    • doi: 10.1016/j.ccr.2012.02.022
    • Hanahan, D., and Coussens, L. M. (2012). Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322. doi: 10.1016/j.ccr.2012.02.022
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 23
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • doi: 10.1016/j.cell.2011.02.013
    • Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674. doi: 10.1016/j.cell.2011.02.013
    • (2011) Cell X , vol.21 , pp. 309-322
    • Hanahan, D.1    Weinberg, R.A.2
  • 24
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • doi: 10.1056/NEJMra0901557
    • Hidalgo, M. (2010). Pancreatic cancer. N. Engl. J. Med. 362, 1605-1617. doi: 10.1056/NEJMra0901557
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 25
    • 33749317518 scopus 로고    scopus 로고
    • Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • doi: 10.1158/1078-0432.CCR-06-0369
    • Hiraoka, N., Onozato, K., Kosuge, T., and Hirohashi, S. (2006). Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions. Clin. Cancer Res. 12, 5423-5434. doi: 10.1158/1078-0432.CCR-06-0369
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5423-5434
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3    Hirohashi, S.4
  • 26
    • 84875228204 scopus 로고    scopus 로고
    • Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
    • doi: 10.1038/bjc.2013.32
    • Ino, Y., Yamazaki-Itoh, R., Shimada, K., Iwasaki, M., Kosuge, T., Kanai, Y., et al. (2013). Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer. Br. J. Cancer 108, 914-923. doi: 10.1038/bjc.2013.32
    • (2013) Br. J. Cance. , vol.108 , pp. 914-923
    • Ino, Y.1    Yamazaki-Itoh, R.2    Shimada, K.3    Iwasaki, M.4    Kosuge, T.5    Kanai, Y.6
  • 27
    • 41149130863 scopus 로고    scopus 로고
    • Multiple roles for CD4+ T cells in anti-tumor immune responses
    • doi: 10.1111/j.1600-065X.2008.00616.x
    • Kennedy, R., and Celis, E. (2008). Multiple roles for CD4+ T cells in anti-tumor immune responses. Immunol. Rev. 222, 129-144. doi: 10.1111/j.1600-065X.2008.00616.x
    • (2008) Immunol. Rev. , vol.222 , pp. 129-144
    • Kennedy, R.1    Celis, E.2
  • 30
    • 79954600458 scopus 로고    scopus 로고
    • Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
    • doi: 10.1016/j.jss.2009.05.026
    • Kurahara, H., Shinchi, H., Mataki, Y., Maemura, K., Noma, H., Kubo, F., et al. (2011). Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J. Surg. Res. 167, e211-e219. doi: 10.1016/j.jss.2009.05.026.
    • (2011) J. Surg. Res. , vol.167
    • Kurahara, H.1    Shinchi, H.2    Mataki, Y.3    Maemura, K.4    Noma, H.5    Kubo, F.6
  • 31
    • 84865132011 scopus 로고    scopus 로고
    • Clinical significance of folate receptor beta-expressing tumor-associated macrophages in pancreatic cancer
    • doi: 10.1245/s10434-012-2263-0
    • Kurahara, H., Takao, S., Kuwahata, T., Nagai, T., Ding, Q., Maeda, K., et al. (2012). Clinical significance of folate receptor beta-expressing tumor-associated macrophages in pancreatic cancer. Ann. Surg. Oncol. 19, 2264-2271. doi: 10.1245/s10434-012-2263-0
    • (2012) Ann. Surg. Oncol. , vol.19 , pp. 2264-2271
    • Kurahara, H.1    Takao, S.2    Kuwahata, T.3    Nagai, T.4    Ding, Q.5    Maeda, K.6
  • 32
    • 84872075318 scopus 로고    scopus 로고
    • M2-polarized tumor-associated macrophage infiltration of regional lymph nodes is associated with nodal lymphangiogenesis and occult nodal involvement in pN0 pancreatic cancer
    • doi: 10.1097/MPA.0b013e318254f2d1
    • Kurahara, H., Takao, S., Maemura, K., Mataki, Y., Kuwahata, T., Maeda, K., et al. (2013). M2-polarized tumor-associated macrophage infiltration of regional lymph nodes is associated with nodal lymphangiogenesis and occult nodal involvement in pN0 pancreatic cancer. Pancreas 42, 155-159. doi: 10.1097/MPA.0b013e318254f2d1
    • (2013) Pancreas , vol.42 , pp. 155-159
    • Kurahara, H.1    Takao, S.2    Maemura, K.3    Mataki, Y.4    Kuwahata, T.5    Maeda, K.6
  • 33
    • 20344407571 scopus 로고    scopus 로고
    • Immunotherapy for pancreatic cancer - science driving clinical progress
    • doi: 10.1038/nrc1630
    • Laheru, D., and Jaffee, E. M. (2005). Immunotherapy for pancreatic cancer - science driving clinical progress. Nat. Rev. Cancer 5, 459-467. doi: 10.1038/nrc1630
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 459-467
    • Laheru, D.1    Jaffee, E.M.2
  • 34
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • doi: 10.1158/0008-5472.CAN-05-4005
    • Lewis, C. E., and Pollard, J. W. (2006). Distinct role of macrophages in different tumor microenvironments. Cancer Res. 66, 605-612. doi: 10.1158/0008-5472.CAN-05-4005
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 35
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • doi: 10.1016/S1471-4906(02)02302-5
    • Mantovani, A., Sozzani, S., Locati, M., Allavena, P., and Sica, A. (2002). Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23, 549-555. doi: 10.1016/S1471-4906(02)02302-5
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 36
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • doi: 10.1038/nature10673
    • Mellman, I., Coukos, G., and Dranoff, G. (2011). Cancer immunotherapy comes of age. Nature 480, 480-489. doi: 10.1038/nature10673
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3
  • 37
    • 29144514645 scopus 로고    scopus 로고
    • Effector memory T cells, early metastasis, and survival in colorectal cancer
    • doi: 10.1056/NEJMoa051424
    • Pages, F., Berger, A., Camus, M., Sanchez-Cabo, F., Costes, A., Molidor, R., et al. (2005). Effector memory T cells, early metastasis, and survival in colorectal cancer. N. Engl. J. Med. 353, 2654-2666. doi: 10.1056/NEJMoa051424
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2654-2666
    • Pages, F.1    Berger, A.2    Camus, M.3    Sanchez-Cabo, F.4    Costes, A.5    Molidor, R.6
  • 38
    • 79952721606 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation
    • doi: 10.1084/jem.20102131
    • Pedroza-Gonzalez, A., Xu, K., Wu, T. C., Aspord, C., Tindle, S., Marches, F., et al. (2011). Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J. Exp. Med. 208, 479-490. doi: 10.1084/jem.20102131
    • (2011) J. Exp. Med. , vol.208 , pp. 479-490
    • Pedroza-Gonzalez, A.1    Xu, K.2    Wu, T.C.3    Aspord, C.4    Tindle, S.5    Marches, F.6
  • 39
    • 73649093148 scopus 로고    scopus 로고
    • Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages
    • doi: 10.1158/0008-5472.CAN-09-2050
    • Puig-Kroger, A., Sierra-Filardi, E., Dominguez-Soto, A., Samaniego, R., Corcuera, M. T., Gomez-Aguado, F., et al. (2009). Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Res. 69, 9395-9403. doi: 10.1158/0008-5472.CAN-09-2050
    • (2009) Cancer Res , vol.69 , pp. 9395-9403
    • Puig-Kroger, A.1    Sierra-Filardi, E.2    Dominguez-Soto, A.3    Samaniego, R.4    Corcuera, M.T.5    Gomez-Aguado, F.6
  • 40
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • doi: 10.1016/j.cell.2010.03.014
    • Qian, B. Z., and Pollard, J. W. (2010). Macrophage diversity enhances tumor progression and metastasis. Cell 141, 39-51. doi: 10.1016/j.cell.2010.03.014
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 41
    • 82955221693 scopus 로고    scopus 로고
    • Mast cells, angiogenesis, and tumour growth
    • doi: 10.1016/j.bbadis.2010.11.010
    • Ribatti, D., and Crivellato, E. (2012). Mast cells, angiogenesis, and tumour growth. Biochim. Biophys. Acta 1822, 2-8. doi: 10.1016/j.bbadis.2010.11.010
    • (2012) Biochim. Biophys. Acta. , vol.1822 , pp. 2-8
    • Ribatti, D.1    Crivellato, E.2
  • 42
    • 84857692141 scopus 로고    scopus 로고
    • Differential macrophage programming in the tumor microenvironment
    • doi: 10.1016/j.it.2011.12.001
    • Ruffell, B., Affara, N. I., and Coussens, L. M. (2012). Differential macrophage programming in the tumor microenvironment. Trends Immunol. 33, 119-126. doi: 10.1016/j.it.2011.12.001
    • (2012) Trends Immunol , vol.33 , pp. 119-126
    • Ruffell, B.1    Affara, N.I.2    Coussens, L.M.3
  • 43
    • 77549085849 scopus 로고    scopus 로고
    • Lymphocytes in cancer development: polarization towards pro-tumor immunity
    • doi: 10.1016/j.cytogfr.2009.11.002
    • Ruffell, B., Denardo, D. G., Affara, N. I., and Coussens, L. M. (2010). Lymphocytes in cancer development: polarization towards pro-tumor immunity. Cytokine Growth Factor Rev. 21, 3-10. doi: 10.1016/j.cytogfr.2009.11.002
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 3-10
    • Ruffell, B.1    Denardo, D.G.2    Affara, N.I.3    Coussens, L.M.4
  • 44
    • 19944426790 scopus 로고    scopus 로고
    • Control of T-cell-mediated immune response by HLA class I in human pancreatic carcinoma
    • Ryschich, E., Notzel, T., Hinz, U., Autschbach, F., Ferguson, J., Simon, I., et al. (2005). Control of T-cell-mediated immune response by HLA class I in human pancreatic carcinoma. Clin. Cancer Res. 11, 498-504.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 498-504
    • Ryschich, E.1    Notzel, T.2    Hinz, U.3    Autschbach, F.4    Ferguson, J.5    Simon, I.6
  • 45
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • doi: 10.1126/science.1203486
    • Schreiber, R. D., Old, L. J., and Smyth, M. J. (2011). Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331, 1565-1570. doi: 10.1126/science.1203486
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 46
    • 77950968790 scopus 로고    scopus 로고
    • Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression
    • doi: 10.1158/1078-0432.CCR-09-1230
    • Strouch, M. J., Cheon, E. C., Salabat, M. R., Krantz, S. B., Gounaris, E., Melstrom, L. G., et al. (2010). Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression. Clin. Cancer Res. 16, 2257-2265. doi: 10.1158/1078-0432.CCR-09-1230
    • (2010) Clin. Cancer Res. , vol.16 , pp. 2257-2265
    • Strouch, M.J.1    Cheon, E.C.2    Salabat, M.R.3    Krantz, S.B.4    Gounaris, E.5    Melstrom, L.G.6
  • 47
    • 58749091119 scopus 로고    scopus 로고
    • Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients
    • Tassi, E., Gavazzi, F., Albarello, L., Senyukov, V., Longhi, R., Dellabona, P., et al. (2008). Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients. J. Immunol. 181, 6595-6603.
    • (2008) J. Immunol. , vol.181 , pp. 6595-6603
    • Tassi, E.1    Gavazzi, F.2    Albarello, L.3    Senyukov, V.4    Longhi, R.5    Dellabona, P.6
  • 48
    • 5644233966 scopus 로고    scopus 로고
    • Mast cells: the Jekyll and Hyde of tumor growth
    • doi: 10.1016/j.it.2004.02.013
    • Theoharides, T. C., and Conti, P. (2004). Mast cells: the Jekyll and Hyde of tumor growth. Trends Immunol. 25, 235-241. doi: 10.1016/j.it.2004.02.013
    • (2004) Trends Immunol , vol.25 , pp. 235-241
    • Theoharides, T.C.1    Conti, P.2
  • 49
    • 34248137929 scopus 로고    scopus 로고
    • Differential release of mast cell mediators and the pathogenesis of inflammation
    • doi: 10.1111/j.1600-065X.2007.00519.x
    • Theoharides, T. C., Kempuraj, D., Tagen, M., Conti, P., and Kalogeromitros, D. (2007). Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol. Rev. 217, 65-78. doi: 10.1111/j.1600-065X.2007.00519.x
    • (2007) Immunol. Rev. , vol.217 , pp. 65-78
    • Theoharides, T.C.1    Kempuraj, D.2    Tagen, M.3    Conti, P.4    Kalogeromitros, D.5
  • 50
    • 84855590868 scopus 로고    scopus 로고
    • The desmoplastic stroma plays an essential role in the accumulation and modulation of infiltrated immune cells in pancreatic adenocarcinoma
    • doi: 10.1155/2011/212810 2011 212810
    • Tjomsland, V., Niklasson, L., Sandstrom, P., Borch, K., Druid, H., Bratthall, C., et al. (2011). The desmoplastic stroma plays an essential role in the accumulation and modulation of infiltrated immune cells in pancreatic adenocarcinoma. Clin. Dev. Immunol. 2011, 212810. doi: 10.1155/2011/212810
    • (2011) Clin. Dev. Immunol.
    • Tjomsland, V.1    Niklasson, L.2    Sandstrom, P.3    Borch, K.4    Druid, H.5    Bratthall, C.6
  • 52
    • 84877052290 scopus 로고    scopus 로고
    • Inflammatory networks and immune surveillance of pancreatic carcinoma
    • doi: 10.1016/j.coi.2013.01.006
    • Vonderheide, R. H., and Bayne, L. J. (2013). Inflammatory networks and immune surveillance of pancreatic carcinoma. Curr. Opin. Immunol. 25, 200-205. doi: 10.1016/j.coi.2013.01.006
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 200-205
    • Vonderheide, R.H.1    Bayne, L.J.2
  • 53
    • 84860799288 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma: a review of immunologic aspects
    • Wachsmann, M. B., Pop, L. M., and Vitetta, E. S. (2012). Pancreatic ductal adenocarcinoma: a review of immunologic aspects. J. Investig. Med. 60, 643-663.
    • (2012) J. Investig. Med. , vol.60 , pp. 643-663
    • Wachsmann, M.B.1    Pop, L.M.2    Vitetta, E.S.3
  • 54
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • doi: 10.1038/nri1412
    • Wynn, T. A. (2004). Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4, 583-594. doi: 10.1038/nri1412
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 55
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • doi: 10.1146/annurev-immunol-030409-101212
    • Zhu, J., Yamane, H., and Paul, W. E. (2010). Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 28, 445-489. doi: 10.1146/annurev-immunol-030409-101212
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 56
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: immunoselection and immunosubversion
    • doi: 10.1038/nri1936
    • Zitvogel, L., Tesniere, A., and Kroemer, G. (2006). Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat. Rev. Immunol. 6, 715-727. doi: 10.1038/nri1936
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.