-
1
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
Abbas, A. K., Murphy, K. M., and Sher, A. (1996). Functional diversity of helper T lymphocytes. Nature 383, 787-793.
-
(1996)
Nature
, vol.383
, pp. 787-793
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
2
-
-
45049085722
-
Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2
-
Angst, E., Reber, H. A., Hines, O. J., and Eibl, G. (2008). Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery 144, 57-65.
-
(2008)
Surgery
, vol.144
, pp. 57-65
-
-
Angst, E.1
Reber, H.A.2
Hines, O.J.3
Eibl, G.4
-
3
-
-
79953154967
-
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
-
Beatty, G. L., Chiorean, E. G., Fishman, M. P., Saboury, B., Teitelbaum, U. R., Sun, W., Huhn, R. D., Song, W., Li, D., Sharp, L. L., Torigian, D. A., O'dwyer, P. J., and Vonderheide, R. H. (2011). CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 331, 1612-1616.
-
(2011)
Science
, vol.331
, pp. 1612-1616
-
-
Beatty, G.L.1
Chiorean, E.G.2
Fishman, M.P.3
Saboury, B.4
Teitelbaum, U.R.5
Sun, W.6
Huhn, R.D.7
Song, W.8
Li, D.9
Sharp, L.L.10
Torigian, D.A.11
O'dwyer, P.J.12
Vonderheide, R.H.13
-
4
-
-
0032770957
-
Tumor-associated transforming growth factor-β and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients
-
Bellone, G., Turletti, A., Artusio, E., Mareschi, K., Carbone, A., Tibaudi, D., Robecchi, A., Emanuelli, G., and Rodeck, U. (1999). Tumor-associated transforming growth factor-β and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients. Am. J. Pathol. 155, 537-547.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 537-547
-
-
Bellone, G.1
Turletti, A.2
Artusio, E.3
Mareschi, K.4
Carbone, A.5
Tibaudi, D.6
Robecchi, A.7
Emanuelli, G.8
Rodeck, U.9
-
5
-
-
77955894120
-
Preoperative hematologic mark ers as independent predictors of prognosis in resected pan creatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio
-
Bhatti, I., Peacock, O., Lloyd, G., Larvin, M., and Hall, R. I. (2010). Preoperative hematologic mark ers as independent predictors of prognosis in resected pan creatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio. Am. I Surg. 200, 197-203.
-
(2010)
Am. I Surg.
, vol.200
, pp. 197-203
-
-
Bhatti, I.1
Peacock, O.2
Lloyd, G.3
Larvin, M.4
Hall, R.I.5
-
6
-
-
79952709160
-
Prognostic significance of mast cell count following curative resection for pancreatic ductal adenocarcinoma
-
Cai, S. W., Yang, S. Z., Gao, J., Pan, K., Chen, J. Y., Wang, Y. L., Wei, L. X., and Dong, J. H. (2011). Prognostic significance of mast cell count following curative resection for pancreatic ductal adenocarcinoma. Surgery 149, 576-584.
-
(2011)
Surgery
, vol.149
, pp. 576-584
-
-
Cai, S.W.1
Yang, S.Z.2
Gao, J.3
Pan, K.4
Chen, J.Y.5
Wang, Y.L.6
Wei, L.X.7
Dong, J.H.8
-
7
-
-
11844263305
-
Macrophage inflammatory protein-3α promotes pancreatic cancer cell invasion
-
Campbell, A. S., Albo, D., Kimsey, T. F., White, S. L., and Wang, T. N. (2005). Macrophage inflammatory protein-3α promotes pancreatic cancer cell invasion. J. Surg. Res. 123, 96-101.
-
(2005)
J. Surg. Res.
, vol.123
, pp. 96-101
-
-
Campbell, A.S.1
Albo, D.2
Kimsey, T.F.3
White, S.L.4
Wang, T.N.5
-
8
-
-
81255138309
-
Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma
-
Chang, D. Z., Ma, Y., Ji, B. A., Wang, H. M., Deng, D. F., Liu, Y., Abbruzzese, J. L., Liu, Y J., Logsdon, C. D., and Hwu, P. (2011). Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma. Clin. Cancer Res. 17, 7015-7023.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 7015-7023
-
-
Chang, D.Z.1
Ma, Y.2
Ji, B.A.3
Wang, H.M.4
Deng, D.F.5
Liu, Y.6
Abbruzzese, J.L.7
Liu, Y.J.8
Logsdon, C.D.9
Hwu, P.10
-
9
-
-
54849431185
-
Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment
-
Cho, H., Hur, H., Kim, S., Kim, S., Kim, J., Kim, Y., and Lee, K. (2009). Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment. Cancer Immunol. Immunother. 58, 15-23.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 15-23
-
-
Cho, H.1
Hur, H.2
Kim, S.3
Kim, S.4
Kim, J.5
Kim, Y.6
Lee, K.7
-
10
-
-
35148814410
-
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
-
Clark, C. E., Hingorani, S. R., Mick, R., Combs, C., Tuveson, D. A., and Vonderheide, R. H. (2007). Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res. 67, 9518-9527.
-
(2007)
Cancer Res
, vol.67
, pp. 9518-9527
-
-
Clark, C.E.1
Hingorani, S.R.2
Mick, R.3
Combs, C.4
Tuveson, D.A.5
Vonderheide, R.H.6
-
11
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M., and Werb, Z. (2002). Inflammation and cancer. Nature 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
12
-
-
79952724783
-
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
-
de Monte, L., Reni, M., Tassi, E., Clavenna, D., Papa, I., Recalde, H., Braga, M., Di Carlo, V., Doglioni, C., and Protti, M. P. (2011). Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J. Exp. Med. 208, 469-478.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 469-478
-
-
de Monte, L.1
Reni, M.2
Tassi, E.3
Clavenna, D.4
Papa, I.5
Recalde, H.6
Braga, M.7
Di Carlo, V.8
Doglioni, C.9
Protti, M.P.10
-
13
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
De Visser, K. E., Eichten, A., and Coussens, L. M. (2006). Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6, 24-37.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 24-37
-
-
De Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
14
-
-
47949097072
-
Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into ortho-topic pancreatic tumors in mice
-
Dineen, S. P., Lynn, K. D., Holloway, S. E., Miller, A. F., Sullivan, J. P., Shames, D. S., Beck, A. W., Barnett, C. C., Fleming, J. B., and Brekken, R. A. (2008). Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into ortho-topic pancreatic tumors in mice. Cancer Res. 68, 4340-4346.
-
(2008)
Cancer Res
, vol.68
, pp. 4340-4346
-
-
Dineen, S.P.1
Lynn, K.D.2
Holloway, S.E.3
Miller, A.F.4
Sullivan, J.P.5
Shames, D.S.6
Beck, A.W.7
Barnett, C.C.8
Fleming, J.B.9
Brekken, R.A.10
-
15
-
-
2642547301
-
Inflammatory cells con tribute to the generation of an angiogenic phenotype in pancre atic ductal adenocarcinoma
-
Esposito, I., Menicagli, M., Funel, N., Bergmann, F., Boggi, U., Mosca, F., Bevilacqua, G., and Campani, D. (2004). Inflammatory cells con tribute to the generation of an angiogenic phenotype in pancre atic ductal adenocarcinoma. J. Clin. Pathol. 57, 630-636.
-
(2004)
J. Clin. Pathol.
, vol.57
, pp. 630-636
-
-
Esposito, I.1
Menicagli, M.2
Funel, N.3
Bergmann, F.4
Boggi, U.5
Mosca, F.6
Bevilacqua, G.7
Campani, D.8
-
16
-
-
51049105755
-
The role of the tumor microenvironment in the progression of pancreatic cancer
-
Farrow, B., Albo, D., and Berger, D. H. (2008). The role of the tumor microenvironment in the progression of pancreatic cancer. J. Surg. Res. 149,319-328.
-
(2008)
J. Surg. Res.
, vol.149
, pp. 319-328
-
-
Farrow, B.1
Albo, D.2
Berger, D.H.3
-
17
-
-
80052206084
-
Prognostic and predictive impact of intra- and per-itumoral immune infiltrates
-
Fridman, W. H., Galon, J., Pages, F., Tartour, E., Sautes-Fridman, C., and Kroemer, G. (2011). Prognostic and predictive impact of intra- and per-itumoral immune infiltrates. Cancer Res. 71, 5601-5605.
-
(2011)
Cancer Res
, vol.71
, pp. 5601-5605
-
-
Fridman, W.H.1
Galon, J.2
Pages, F.3
Tartour, E.4
Sautes-Fridman, C.5
Kroemer, G.6
-
18
-
-
80054102628
-
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
-
Gabitass, R. F., Annels, N. E., Stocken, D. D., Pandha, H. A., and Middleton, G. W. (2011). Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother. 60, 1419-1430.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1419-1430
-
-
Gabitass, R.F.1
Annels, N.E.2
Stocken, D.D.3
Pandha, H.A.4
Middleton, G.W.5
-
19
-
-
0036189530
-
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
-
Gaça, M. D. A., Zhou, X., and Benyon, R. C. (2002). Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors. J. Hepatol. 36, 362-369.
-
(2002)
J. Hepatol.
, vol.36
, pp. 362-369
-
-
Gaça, M.D.A.1
Zhou, X.2
Benyon, R.C.3
-
20
-
-
84856606100
-
Regulation of mast cell responses in health and disease
-
Gilfillan, A. M., and Beaven, M. A. (2011). Regulation of mast cell responses in health and disease. Crit Rev. Immunol. 31, 475-529.
-
(2011)
Crit Rev. Immunol.
, vol.31
, pp. 475-529
-
-
Gilfillan, A.M.1
Beaven, M.A.2
-
21
-
-
48549088033
-
Preoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative resection for hepatocellular carcinoma
-
Gomez, D., Farid, S., Malik, H., Young, A., Toogood, G., Lodge, J., and Prasad, K. (2008). Preoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative resection for hepatocellular carcinoma. WorldJ. Surg. 32, 1757-1762.
-
(2008)
World J. Surg.
, vol.32
, pp. 1757-1762
-
-
Gomez, D.1
Farid, S.2
Malik, H.3
Young, A.4
Toogood, G.5
Lodge, J.6
Prasad, K.7
-
22
-
-
78649291031
-
Deploying mouse models of pancreatic cancer for chemoprevention studies
-
Grippo, P. J., and Tuveson, D. A. (2010). Deploying mouse models of pancreatic cancer for chemoprevention studies. Cancer Prev. Res. (Phila.) 3, 1382-1387.
-
(2010)
Cancer Prev. Res. (Phila.)
, vol.3
, pp. 1382-1387
-
-
Grippo, P.J.1
Tuveson, D.A.2
-
23
-
-
79958710624
-
Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence
-
Guerra, C., Collado, M., Navas, C., Schuhmacher, A. J., Hernandez-Porras, I., Canamero, M., Rodriguez-Justo, M., Serrano, M., and Barbacid, M. (2011). Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Cancer Cell 19, 728-739.
-
(2011)
Cancer Cell
, vol.19
, pp. 728-739
-
-
Guerra, C.1
Collado, M.2
Navas, C.3
Schuhmacher, A.J.4
Hernandez-Porras, I.5
Canamero, M.6
Rodriguez-Justo, M.7
Serrano, M.8
Barbacid, M.9
-
24
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
Guerra, C., Schuhmacher, A. J., Canamero, M., Grippo, P. J., Verdaguer, L., Perez-Gallego, L., Dubus, P., Sandgren, E. P., and Barbacid, M. (2007). Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11, 291-302.
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Canamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Perez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
25
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
26
-
-
33749317518
-
Prevalence of FOXP3(+) regulatory T cells increases during the progression of pancreatic ductal adenocarcinorna and its premalignant lesions
-
Hiraoka, N., Onozato, K., Kosuge, T., and Hirohashi, S. (2006). Prevalence of FOXP3(+) regulatory T cells increases during the progression of pancreatic ductal adenocarcinorna and its premalignant lesions. Clin. Cancer Res. 12, 5423-5434.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5423-5434
-
-
Hiraoka, N.1
Onozato, K.2
Kosuge, T.3
Hirohashi, S.4
-
27
-
-
78650508742
-
CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraep-ithelial stages of human pancreatic carcinogenesis
-
Hiraoka, N., Yamazaki-Itoh, R., Ino, Y., Mizuguchi, Y., Yamada, T., Hirohashi, S., and Kanai, Y (2011). CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraep-ithelial stages of human pancreatic carcinogenesis. Gastroenterology 140, 310-321.
-
(2011)
Gastroenterology
, vol.140
, pp. 310-321
-
-
Hiraoka, N.1
Yamazaki-Itoh, R.2
Ino, Y.3
Mizuguchi, Y.4
Yamada, T.5
Hirohashi, S.6
Kanai, Y.7
-
28
-
-
38849141696
-
Cancer-associated stromal fibroblasts promote pancreatic tumor progression
-
Hwang, R. F., Moore, T., Arumugam, T., Ramachandran, V., Amos, K. D., Rivera, A., Ji, B., Evans, D. B., and Logsdon, C. D. (2008). Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res. 68, 918-926.
-
(2008)
Cancer Res
, vol.68
, pp. 918-926
-
-
Hwang, R.F.1
Moore, T.2
Arumugam, T.3
Ramachandran, V.4
Amos, K.D.5
Rivera, A.6
Ji, B.7
Evans, D.B.8
Logsdon, C.D.9
-
29
-
-
15744370482
-
Co-localization of macrophage inflammatory protein-3alpha (Mip-3alpha) and its receptor, CCR6, promotes pancreatic cancer cell invasion
-
Kimsey, T. F., Campbell, A. S., Albo, D., and Wang, T. N. (2004). Co-localization of macrophage inflammatory protein-3alpha (Mip-3alpha) and its receptor, CCR6, promotes pancreatic cancer cell invasion. Cancer J. 10, 374-380.
-
(2004)
Cancer J
, vol.10
, pp. 374-380
-
-
Kimsey, T.F.1
Campbell, A.S.2
Albo, D.3
Wang, T.N.4
-
30
-
-
0032960393
-
Detection and localization of MIP-3α/LARC/exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer
-
Kleeff, J., Kusama, T., Rossi, D. L., Ishiwata, T., Maruyama, H., Friess, H., Büchler, M. W., Zlotnik, A., and Korc, M. (1999). Detection and localization of MIP-3α/LARC/exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. Int. J. Cancer 81, 650-657.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 650-657
-
-
Kleeff, J.1
Kusama, T.2
Rossi, D.L.3
Ishiwata, T.4
Maruyama, H.5
Friess, H.6
Büchler, M.W.7
Zlotnik, A.8
Korc, M.9
-
31
-
-
81555221715
-
Current immunother-apeutic approaches in pancreatic cancer
-
Koido, S., Homma, S., Takahara, A., Namiki, Y., Tsukinaga, S., Mitobe, J., Odahara, S., Yukawa, T., Matsudaira, H., Nagatsuma, K., Uchiyama, K., Satoh, K., Ito, M., Komita, H., Arakawa, H., Ohkusa, T., Gong, J. L., and Tajiri, H. (2011). Current immunother-apeutic approaches in pancreatic cancer. Clin. Dev. Immunol. 2011, 15.
-
(2011)
Clin. Dev. Immunol.
, vol.2011
, pp. 15
-
-
Koido, S.1
Homma, S.2
Takahara, A.3
Namiki, Y.4
Tsukinaga, S.5
Mitobe, J.6
Odahara, S.7
Yukawa, T.8
Matsudaira, H.9
Nagatsuma, K.10
Uchiyama, K.11
Satoh, K.12
Ito, M.13
Komita, H.14
Arakawa, H.15
Ohkusa, T.16
Gong, J.L.17
Tajiri, H.18
-
32
-
-
34648852355
-
Pancreatic cancer-associated stroma production
-
Korc, M. (2007). Pancreatic cancer-associated stroma production. Am. J. Surg. 194, S84-S86.
-
(2007)
Am. J. Surg.
, vol.194
-
-
Korc, M.1
-
33
-
-
77958152008
-
Neutrophils: cinderella of innate immune system
-
Kumar, V., and Sharma, A. (2010). Neutrophils: cinderella of innate immune system. Int. Immunopharmacol. 10, 1325-1334.
-
(2010)
Int. Immunopharmacol.
, vol.10
, pp. 1325-1334
-
-
Kumar, V.1
Sharma, A.2
-
34
-
-
79954600458
-
Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
-
Kurahara, H., Shinchi, H., Mataki, Y., Maemura, K., Noma, H., Kubo, F., Sakoda, M., Ueno, S., Natsugoe, S., and Takao, S. (2011). Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J. Surg. Res. 167, e211-e219.
-
(2011)
J. Surg. Res.
, vol.167
-
-
Kurahara, H.1
Shinchi, H.2
Mataki, Y.3
Maemura, K.4
Noma, H.5
Kubo, F.6
Sakoda, M.7
Ueno, S.8
Natsugoe, S.9
Takao, S.10
-
36
-
-
0027294719
-
Pancreatitis and the risk of pancreatic cancer
-
Lowenfels, A. B., Maisonneuve, P., Cavallini, G., Ammann, R. W., Lankisch, P. G., Andersen, J. R., Dimagno, E. P., Andren-Sandberg, A., and Domellof, L. (1993). Pancreatitis and the risk of pancreatic cancer. N. Engl. J. Med. 328, 1433-1437.
-
(1993)
N. Engl. J. Med.
, vol.328
, pp. 1433-1437
-
-
Lowenfels, A.B.1
Maisonneuve, P.2
Cavallini, G.3
Ammann, R.W.4
Lankisch, P.G.5
Andersen, J.R.6
Dimagno, E.P.7
Andren-Sandberg, A.8
Domellof, L.9
-
37
-
-
80053421470
-
Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
-
Lu, T. Y., Ramakrishnan, R., Altiok, S., Youn, J. I., Chong, P. Y., Celis, E., Pisarev, V., Sherman, S., Sporn, M. B., and Gabrilovich, D. (2011). Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. J. Clin. Invest. 121, 4015-4029.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4015-4029
-
-
Lu, T.Y.1
Ramakrishnan, R.2
Altiok, S.3
Youn, J.I.4
Chong, P.Y.5
Celis, E.6
Pisarev, V.7
Sherman, S.8
Sporn, M.B.9
Gabrilovich, D.10
-
38
-
-
79960829290
-
Neutrophils in the activation and regulation of innate and adaptive immunity
-
Mantovani, A., Cassatella, M. A., Costantini, C., and Jaillon, S. (2011). Neutrophils in the activation and regulation of innate and adaptive immunity. Nat. Rev. Immunol. 11, 519-531.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 519-531
-
-
Mantovani, A.1
Cassatella, M.A.2
Costantini, C.3
Jaillon, S.4
-
39
-
-
77957367120
-
Nuclear expression of interleukin-33 in pancreatic stellate cells
-
Masamune, A., Watanabe, T., Kikuta, K., Satoh, K., Kanno, A., and Shimosegawa, T. (2010). Nuclear expression of interleukin-33 in pancreatic stellate cells. Am. J. Physiol Gastrointest. Liver Physiol. 299, G821-G832.
-
(2010)
Am. J. Physiol Gastrointest. Liver Physiol.
, vol.299
-
-
Masamune, A.1
Watanabe, T.2
Kikuta, K.3
Satoh, K.4
Kanno, A.5
Shimosegawa, T.6
-
40
-
-
38149065951
-
Chronic inflammation and pancreatic cancer
-
McKay, C. J., Glen, P., and McMillan, D. C. (2008). Chronic inflammation and pancreatic cancer. Best Pract. Res. Clin. Gastroenterol. 22, 65-73.
-
(2008)
Best Pract. Res. Clin. Gastroenterol.
, vol.22
, pp. 65-73
-
-
McKay, C.J.1
Glen, P.2
McMillan, D.C.3
-
41
-
-
84860728453
-
Targeting regulatory T cells
-
Menetrier-Caux, C., Curiel, T., Faget, J., Manuel, M., Caux, C., and Zou, W. (2012). Targeting regulatory T cells. Target. Oncol. 7, 15-28.
-
(2012)
Target. Oncol.
, vol.7
, pp. 15-28
-
-
Menetrier-Caux, C.1
Curiel, T.2
Faget, J.3
Manuel, M.4
Caux, C.5
Zou, W.6
-
42
-
-
65549158084
-
Tumor-derived TGF-beta mediates conversion of CD4(+)Foxp3(+) reg ulatory T cells in a murine model of pancreas cancer
-
Moo-Young, T. A., Larson, J. W., Belt, B. A., Tan, M. C., Hawkins, W. G., Eberlein, T. J., Goedegebuure, P. S., and Linehan, D. C. (2009). Tumor-derived TGF-beta mediates conversion of CD4(+)Foxp3(+) reg ulatory T cells in a murine model of pancreas cancer. J. Immunother. 32, 12-21.
-
(2009)
J. Immunother.
, vol.32
, pp. 12-21
-
-
Moo-Young, T.A.1
Larson, J.W.2
Belt, B.A.3
Tan, M.C.4
Hawkins, W.G.5
Eberlein, T.J.6
Goedegebuure, P.S.7
Linehan, D.C.8
-
43
-
-
76649105065
-
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
-
Morris, J. P. T., Cano, D. A., Sekine, S., Wang, S. C., and Hebrok, M. (2010). Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. J. Clin. Invest. 120, 508-520.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 508-520
-
-
Morris, J.P.T.1
Cano, D.A.2
Sekine, S.3
Wang, S.C.4
Hebrok, M.5
-
44
-
-
79955828776
-
Stromal biology and therapy in pancreatic cancer
-
Neesse, A., Michl, P., Frese, K. K., Feig, C., Cook, N., Jacobetz, M. A., Lolkema, M. P., Buchholz, M., Olive, K. P., Gress, T. M., and Tuveson, D. A. (2010). Stromal biology and therapy in pancreatic cancer. Gut. 60, 861-868.
-
(2010)
Gut
, vol.60
, pp. 861-868
-
-
Neesse, A.1
Michl, P.2
Frese, K.K.3
Feig, C.4
Cook, N.5
Jacobetz, M.A.6
Lolkema, M.P.7
Buchholz, M.8
Olive, K.P.9
Gress, T.M.10
Tuveson, D.A.11
-
45
-
-
0036085728
-
Mast cells and angiogenesis
-
Norrby, K. (2002). Mast cells and angiogenesis. APMIS 110, 355-371.
-
(2002)
APMIS
, vol.110
, pp. 355-371
-
-
Norrby, K.1
-
47
-
-
84867859531
-
Myeloid-derived suppressor cells in transplantation and cancer
-
doi: 10.1007/s12026-012-8335-1. [Epub ahead of print]
-
Ochando, J. C., and Chen, S. H. (2012). Myeloid-derived suppressor cells in transplantation and cancer. Immunol Res. doi: 10.1007/s12026-012-8335-1. [Epub ahead of print].
-
(2012)
Immunol Res
-
-
Ochando, J.C.1
Chen, S.H.2
-
48
-
-
80355124415
-
+ T helper 2 cells-microbial triggers, differentiation requirements and effector functions
-
+ T helper 2 cells-microbial triggers, differentiation requirements and effector functions. Immunology 134, 368-377.
-
(2011)
Immunology
, vol.134
, pp. 368-377
-
-
Okoye, I.S.1
Wilson, M.S.2
-
49
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive, K. P., Jacobetz, M. A., Davidson, C. J., Gopinathan, A., Mcintyre, D., Honess, D., Madhu, B., Goldgraben, M. A., Caldwell, M. E., Allard, D., Frese, K. K., Denicola, G., Feig, C., Combs, C., Winter, S. P., Ireland-Zecchini, H., Reichelt, S., Howat, W. J., Chang, A., Dhara, M., Wang, L., Ruckert, F., Grutzmann, R., Pilarsky, C., Izeradjene, K., Hingorani, S. R., Huang, P., Davies, S. E., Plunkett, W., Egorin, M., Hruban, R. H., Whitebread, N., Mcgovern, K., Adams, J., Iacobuzio-Donahue, C., Griffiths, J., and Tuveson, D. A. (2009). Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324, 1457-1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
Mcintyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
Frese, K.K.11
Denicola, G.12
Feig, C.13
Combs, C.14
Winter, S.P.15
Ireland-Zecchini, H.16
Reichelt, S.17
Howat, W.J.18
Chang, A.19
Dhara, M.20
Wang, L.21
Ruckert, F.22
Grutzmann, R.23
Pilarsky, C.24
Izeradjene, K.25
Hingorani, S.R.26
Huang, P.27
Davies, S.E.28
Plunkett, W.29
Egorin, M.30
Hruban, R.H.31
Whitebread, N.32
Mcgovern, K.33
Adams, J.34
Iacobuzio-Donahue, C.35
Griffiths, J.36
Tuveson, D.A.37
more..
-
50
-
-
65249138393
-
Myeloid-derived suppressor cells: linking inflammation and cancer
-
Ostrand-Rosenberg, S., and Sinha, P. (2009). Myeloid-derived suppressor cells: linking inflammation and cancer.J. Immunol. 182, 4499-4506.
-
(2009)
J. Immunol.
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
51
-
-
84862127053
-
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
-
Ostrand-Rosenberg, S., Sinha, P., Beury, D. W., and Clements, V. K. (2012). Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression. Semin. Cancer Biol. 22, 275-281.
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 275-281
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
Beury, D.W.3
Clements, V.K.4
-
52
-
-
77649193013
-
Immune infiltration in human tumors: a prognostic factor that should not be ignored
-
Pages, F., Galon, J., Dieu-Nosjean, M. C., Tartour, E., Sautes-Fridman, C., and Fridman, W. H. (2010). Immune infiltration in human tumors: a prognostic factor that should not be ignored. Oncogene 29, 1093-1102.
-
(2010)
Oncogene
, vol.29
, pp. 1093-1102
-
-
Pages, F.1
Galon, J.2
Dieu-Nosjean, M.C.3
Tartour, E.4
Sautes-Fridman, C.5
Fridman, W.H.6
-
53
-
-
81555205674
-
Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function
-
doi: 10.1371/journal.pone.0027729
-
Pilon-Thomas, S., Nelson, N., Vohra, N., Jerald, M., Pendleton, L., Szekeres, K., and Ghansah, T. (2011). Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function. PLoS ONE 6:e27729. doi: 10.1371/journal.pone.0027729
-
(2011)
PLoS ONE
, vol.6
-
-
Pilon-Thomas, S.1
Nelson, N.2
Vohra, N.3
Jerald, M.4
Pendleton, L.5
Szekeres, K.6
Ghansah, T.7
-
54
-
-
58149345546
-
Co-evolution of tumor cells and their microenvironment
-
Polyak, K., Haviv, I., and Campbell, I. G. (2009). Co-evolution of tumor cells and their microenvironment. Trends Genet. 25, 30-38.
-
(2009)
Trends Genet
, vol.25
, pp. 30-38
-
-
Polyak, K.1
Haviv, I.2
Campbell, I.G.3
-
55
-
-
3543090480
-
Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis
-
Puolakkainen, P. A., Brekken, R. A., Muneer, S., and Sage, E. H. (2004). Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. Mol. Cancer Res. 2, 215-224.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 215-224
-
-
Puolakkainen, P.A.1
Brekken, R.A.2
Muneer, S.3
Sage, E.H.4
-
56
-
-
82555191059
-
Tumor-infiltrating neu-trophils in pancreatic neoplasia
-
(2011)
Mod. Pathol.
, vol.24
, pp. 1612-1619
-
-
Reid, M.D.1
Basturk, O.2
Thirabanjasak, D.3
Hruban, R.H.4
Klimstra, D.S.5
Bagci, P.6
Altinel, D.7
Adsay, V.8
-
57
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim, A. D., Mirek, E. T., Aiello, N. M., Maitra, A., Bailey, J. M., McAllister, E, Reichert, M., Beatty, G. L., Rustgi, A. K., Vonderheide, R. H., Leach, S. D., and Stanger, B. Z. (2012). EMT and dissemination precede pancreatic tumor formation. Cell 148, 349-361.
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, E.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
Leach, S.D.11
Stanger, B.Z.12
-
58
-
-
79960896329
-
Mast cells, angiogenesis and cancer
-
Ribatti, D., and Crivellato, E. (2011). Mast cells, angiogenesis and cancer. Adv. Exp. Med. Biol. 716, 270-288.
-
(2011)
Adv. Exp. Med. Biol.
, vol.716
, pp. 270-288
-
-
Ribatti, D.1
Crivellato, E.2
-
59
-
-
84861194756
-
The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer
-
Roxburgh, C. S. D., and McMillan, D. C. (2011). The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer. Cancer Treat. Rev. 38,451-466.
-
(2011)
Cancer Treat. Rev.
, vol.38
, pp. 451-466
-
-
Roxburgh, C.S.D.1
McMillan, D.C.2
-
60
-
-
84857692141
-
Differential macrophage programming in the tumor microenvironment
-
Ruffell, B., Affara, N. I., and Coussens, L. M. (2012). Differential macrophage programming in the tumor microenvironment. Trends Immunol. 33, 119-126.
-
(2012)
Trends Immunol
, vol.33
, pp. 119-126
-
-
Ruffell, B.1
Affara, N.I.2
Coussens, L.M.3
-
61
-
-
58649105512
-
Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer
-
Sarraf, K. M., Belcher, E., Raevsky, E., Nicholson, A. G., Goldstraw, P., and Lim, E. (2009). Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J. Thorac. Cardiovasc. Surg. 137, 425-428.
-
(2009)
J. Thorac. Cardiovasc. Surg.
, vol.137
, pp. 425-428
-
-
Sarraf, K.M.1
Belcher, E.2
Raevsky, E.3
Nicholson, A.G.4
Goldstraw, P.5
Lim, E.6
-
62
-
-
84866467129
-
Molecular mechanisms of treg-mediated T cell suppression
-
doi: 10.3389/fimmu.2012.00051
-
Schmidt, A., Oberle, N., and Krammer, P. H. (2012). Molecular mechanisms of treg-mediated T cell suppression. Front. Immunol. 3:51. doi: 10.3389/fimmu.2012.00051
-
(2012)
Front. Immunol
, vol.3
, pp. 51
-
-
Schmidt, A.1
Oberle, N.2
Krammer, P.H.3
-
63
-
-
81055127013
-
Inhibition of focal adhesion kinase by PF-562 271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment
-
Stokes, J. B., Adair, S. J., Slack-Davis, J. K., Walters, D. M., Tilghman, R. W., Hershey, E. D., Lowrey, B., Thomas, K. S., Bouton, A. H., Hwang, R. F., Stelow, E. B., Parsons, J. T., and Bauer, T. W. (2011). Inhibition of focal adhesion kinase by PF-562, 271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment. Mol. Cancer Ther. 10, 2135-2145.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 2135-2145
-
-
Stokes, J.B.1
Adair, S.J.2
Slack-Davis, J.K.3
Walters, D.M.4
Tilghman, R.W.5
Hershey, E.D.6
Lowrey, B.7
Thomas, K.S.8
Bouton, A.H.9
Hwang, R.F.10
Stelow, E.B.11
Parsons, J.T.12
Bauer, T.W.13
-
64
-
-
77950968790
-
Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression
-
Strouch, M. J., Cheon, E. C., Salabat, M. R., Krantz, S. B., Gounaris, E., Melstrom, L. G., Dangi-Garimella, S., Wang, E., Munshi, H. G., Khazaie, K., and Bentrem, D. J. (2010). Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression. Clin. Can. Res. 16, 2257-2265.
-
(2010)
Clin. Can. Res.
, vol.16
, pp. 2257-2265
-
-
Strouch, M.J.1
Cheon, E.C.2
Salabat, M.R.3
Krantz, S.B.4
Gounaris, E.5
Melstrom, L.G.6
Dangi-Garimella, S.7
Wang, E.8
Munshi, H.G.9
Khazaie, K.10
Bentrem, D.J.11
-
65
-
-
63149148047
-
Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer
-
Tan, M. C. B., Goedegebuure, P. S., Belt, B. A., Flaherty, B., Sankpal, N., Gillanders, W. E., Eberlein, T. J., Hsieh, C.-S., and Linehan, D. C. (2009). Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. J. Immunol. 182, 1746-1755.
-
(2009)
J. Immunol.
, vol.182
, pp. 1746-1755
-
-
Tan, M.C.B.1
Goedegebuure, P.S.2
Belt, B.A.3
Flaherty, B.4
Sankpal, N.5
Gillanders, W.E.6
Eberlein, T.J.7
Hsieh, C.-S.8
Linehan, D.C.9
-
66
-
-
58749091119
-
+ T cell immunity is impaired in pancreatic carcinoma patients
-
+ T cell immunity is impaired in pancreatic carcinoma patients. J. Immunol. 181, 6595-6603.
-
(2008)
J. Immunol.
, vol.181
, pp. 6595-6603
-
-
Tassi, E.1
Gavazzi, F.2
Albarello, L.3
Senyukov, V.4
Longhi, R.5
Dellabona, P.6
Doglioni, C.7
Braga, M.8
Di Carlo, V.9
Protti, M.P.10
-
67
-
-
84858760109
-
Combining immunother-apy and targeted therapies in cancer treatment
-
Vanneman, M., and Dranoff, G. (2012). Combining immunother-apy and targeted therapies in cancer treatment. Nat. Rev. Cancer 12, 237-251.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 237-251
-
-
Vanneman, M.1
Dranoff, G.2
-
68
-
-
33644829195
-
Hereditary pancreatitis and secondary screening for early pancreatic cancer
-
Vitone, L. J., Greenhalf, W., Howes, N. R., and Neoptolemos, J. P. (2005). Hereditary pancreatitis and secondary screening for early pancreatic cancer. Rocz. Akad. Med. Bialymst. 50, 73-84.
-
(2005)
Rocz. Akad. Med. Bialymst.
, vol.50
, pp. 73-84
-
-
Vitone, L.J.1
Greenhalf, W.2
Howes, N.R.3
Neoptolemos, J.P.4
-
69
-
-
0035291879
-
Systemic and local immunosuppression in pancreatic cancer patients
-
Von Bernstorff, W., Voss, M., Freichel, S., Schmid, A., Vogel, I., Johnk, C., Henne-Bruns, D., Kremer, B., and Kalthoff, H. (2001). Systemic and local immunosuppression in pancreatic cancer patients. Clin. Cancer Res. 7, 925S-932S.
-
(2001)
Clin. Cancer Res.
, vol.7
-
-
Von Bernstorff, W.1
Voss, M.2
Freichel, S.3
Schmid, A.4
Vogel, I.5
Johnk, C.6
Henne-Bruns, D.7
Kremer, B.8
Kalthoff, H.9
-
70
-
-
42049097658
-
Pancreatic stellate cells: partners in crime with pancreatic cancer cells
-
Vonlaufen, A., Joshi, S., Qu, C., Phillips, P. A., Xu, Z., Parker, N. R., Toi, C. S., Pirola, R. C., Wilson, J. S., Goldstein, D., and Apte, M. V. (2008). Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res. 68, 2085-2093.
-
(2008)
Cancer Res
, vol.68
, pp. 2085-2093
-
-
Vonlaufen, A.1
Joshi, S.2
Qu, C.3
Phillips, P.A.4
Xu, Z.5
Parker, N.R.6
Toi, C.S.7
Pirola, R.C.8
Wilson, J.S.9
Goldstein, D.10
Apte, M.V.11
-
71
-
-
84860799288
-
Pancreatic duc-tal adenocarcinoma: a review of immunologic aspects
-
Wachsmann, M. B., Pop, L. M., and Vitetta, E. S. (2012). Pancreatic duc-tal adenocarcinoma: a review of immunologic aspects. J. Invest. Med. 60, 643-663.
-
(2012)
J. Invest. Med.
, vol.60
, pp. 643-663
-
-
Wachsmann, M.B.1
Pop, L.M.2
Vitetta, E.S.3
-
72
-
-
24344442821
-
Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer
-
Walsh, S. R., Cook, E. J., Goulder, F., Justin, T. A., and Keeling, N. J. (2005). Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer. J. Surg. Oncol. 91, 181-184.
-
(2005)
J. Surg. Oncol.
, vol.91
, pp. 181-184
-
-
Walsh, S.R.1
Cook, E.J.2
Goulder, F.3
Justin, T.A.4
Keeling, N.J.5
-
73
-
-
84880314861
-
Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer
-
doi: 10.1007/s12032-012-0226-8. [Epub ahead of print]
-
Wang, D. S., Luo, H. Y., Qiu, M. Z., Wang, Z. Q., Zhang, D. S., Wang, F. H., Li, Y. H., and Xu, R. H. (2012). Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer. Med. Oncol. doi: 10.1007/s12032-012-0226-8. [Epub ahead of print].
-
(2012)
Med. Oncol
-
-
Wang, D.S.1
Luo, H.Y.2
Qiu, M.Z.3
Wang, Z.Q.4
Zhang, D.S.5
Wang, F.H.6
Li, Y.H.7
Xu, R.H.8
-
74
-
-
53549102755
-
The tumor microenvironment and its role in promoting tumor growth
-
Whiteside, T. L. (2008). The tumor microenvironment and its role in promoting tumor growth. Oncogene 27, 5904-5912.
-
(2008)
Oncogene
, vol.27
, pp. 5904-5912
-
-
Whiteside, T.L.1
-
75
-
-
49449111630
-
IL-33 exacerbates antigen-induced arthritis by activating mast cells
-
Xu, D., Jiang, H. R., Kewin, P., Li, Y., Mu, R., Fraser, A. R., Pitman, N., Kurowska-Stolarska, M., McKenzie, A. N. J., McInnes, I. B., and Liew, F. Y (2008). IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc. Natl. Acad. Sci. U.S.A. 105, 10913-10918.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 10913-10918
-
-
Xu, D.1
Jiang, H.R.2
Kewin, P.3
Li, Y.4
Mu, R.5
Fraser, A.R.6
Pitman, N.7
Kurowska-Stolarska, M.8
McKenzie, A.N.J.9
McInnes, I.B.10
Liew, F.Y.11
-
76
-
-
77950505872
-
Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh
-
Yamasaki, A., Kameda, C., Xu, R., Tanaka, H., Tasaka, T., Chikazawa, N., Suzuki, H., Morisaki, T., Kubo, M., Onishi, H., Tanaka, M., and Katano, M. (2010). Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh. Cancer Immunol. Immunother. 59, 675-686.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 675-686
-
-
Yamasaki, A.1
Kameda, C.2
Xu, R.3
Tanaka, H.4
Tasaka, T.5
Chikazawa, N.6
Suzuki, H.7
Morisaki, T.8
Kubo, M.9
Onishi, H.10
Tanaka, M.11
Katano, M.12
|