Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Piras, Bryan A ^a   O'Connor, Daniel M ^a,c   French, Brent A ^a,b  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PARVOVIRUS VECTOR; SHORT HAIRPIN RNA;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 9; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DOSE RESPONSE; GENE CASSETTE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HEART; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER INJURY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS GENOME;

ANIMALS; BLOTTING, WESTERN; DEPENDOVIRUS; DNA PRIMERS; GENE KNOCKDOWN TECHNIQUES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; LIVER; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MYOCARDIUM; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84884577974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075894     Document Type: Article

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