Mitochondrial superoxide mediates labile iron level: Evidence from Mn-SOD-transgenic mice and heterozygous knockout mice and isolated rat liver mitochondria

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 143-149

  Ibrahim, Wissam H ^a   Habib, Hosam M ^a   Kamal, Hina ^a   St Clair, Daret K ^b   Chow, Ching K ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Antioxidant status; Free radicals; Heterozygous; Labile iron; Lipid peroxidation; Mitochondria; Mn SOD knockout mice; Mn SOD transgenic mice; Superoxide

Indexed keywords

ALPHA TOCOPHEROL; ANTIMYCIN A1; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; FERRITIN; GALLIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; IRON; MANGANESE SUPEROXIDE DISMUTASE; MEMBRANE LIPID; MYXOTHIAZOL; REACTIVE OXYGEN METABOLITE; ROTENONE; RUTOSIDE; SUPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROLOX C; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DNA DAMAGE; ELECTRON TRANSPORT; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEART; HETEROZYGOTE; IN VIVO STUDY; IRON BLOOD LEVEL; KIDNEY; KNOCKOUT MOUSE; LIPID PEROXIDATION; LIVER; LIVER MITOCHONDRION; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; STEADY STATE; TISSUE LEVEL; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; HUMAN; METABOLISM; NORTHERN BLOTTING; PHYSIOLOGY;

ANIMALS; BLOTTING, NORTHERN; HUMANS; IRON; LIPID PEROXIDATION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIA, LIVER; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 84884536749     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.06.026     Document Type: Article

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