UV-irradiation induces oxidative damage to mitochondrial DNA primarily through hydrogen peroxide: Analysis of 8-oxodGuo by HPLC

Free Radical Research

Volumn 40, Issue 11, 2006, Pages 1138-1148

  Takai, Daisaku ^a   Park, Sang Hee ^a   Takada, Yasunari ^a   Ichinose, Shizuko ^b   Kitagawa, Masanobu ^b   Akashi, Makoto ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

8 oxo 7,8 dihydro 2 deoxyguanosine (8 oxodGuo); Hydrogen peroxide; Mitochondrial DNA (mtDNA); Reactive oxygen species (ROS); UV irradiation

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; CATALASE; DNA; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; STATISTICAL SIGNIFICANCE; ULTRAVIOLET IRRADIATION;

ANTIOXIDANTS; CARCINOMA, HEPATOCELLULAR; CATALYSIS; CELL LINE, TUMOR; CHELATING AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMANS; HYDROGEN PEROXIDE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, IMMUNOELECTRON; OXIDATIVE STRESS; ULTRAVIOLET RAYS;

EID: 33749324810     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760600838381     Document Type: Article

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