Design of self-dispersible dry nanosuspension through wet milling and spray freeze-drying for poorly water-soluble drugs

European Journal of Pharmaceutical Sciences

Volumn 50, Issue 3-4, 2013, Pages 272-281

  Niwa, Toshiyuki ^a   Danjo, Kazumi ^a  

^a MEIJO UNIVERSITY   (Japan)

Author keywords

Dry nanosuspension; Nano milling; Nanosizing; Redispersion; Spray freeze drying

Indexed keywords

DISPERSANT; LIQUID NITROGEN; PHENYTOIN;

AEROSOL; ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CRYSTAL; DISPERSION; DRUG DESIGN; DRUG SOLUBILITY; DRY NANOSUSPENSION TECHNIQUE; FREEZE DRYING; IN VITRO STUDY; OSCILLATION; PARTICLE SIZE; PRIORITY JOURNAL; SOLID; SPRAY DRYING; SPRAY FREEZE DRYING; SURFACE PROPERTY; SUSPENSION; WET MILLING; ZETA POTENTIAL;

DRY NANOSUSPENSION; NANO-MILLING; NANOSIZING; REDISPERSION; SPRAY FREEZE-DRYING;

FREEZE DRYING; NANOPARTICLES; PARTICLE SIZE; PHENYTOIN; POVIDONE; SODIUM DODECYL SULFATE; SOLUBILITY; SUSPENSIONS; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 84884523598     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.07.011     Document Type: Article

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