-
1
-
-
0002820601
-
Poorly soluble drugs: A challenge in drug delivery
-
Müller RH, Benita S, Böhm B, editors, Stuttgart: Medpharm Scientific
-
Speiser PP. Poorly soluble drugs: a challenge in drug delivery. In: Müller RH, Benita S, Böhm B, editors. Emulsions and nanosuspensions for the formulation of poorly soluble drugs. Stuttgart: Medpharm Scientific; 1998. p. 15-28.
-
(1998)
Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs.
, pp. 15-28
-
-
Speiser, P.P.1
-
2
-
-
0023947965
-
Pharmaceutical innovation by seven UK-owned pharmaceutical companies
-
Prentis RA, Lis Y, Walker SR. Pharmaceutical innovation by seven UK-owned pharmaceutical companies. Br J Clin Pharmacol. 1988;25:387-96.
-
(1988)
Br J Clin Pharmacol.
, vol.25
, pp. 387-396
-
-
Prentis, R.A.1
Lis, Y.2
Walker, S.R.3
-
3
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
DOI 10.1016/S1056-8719(00)00107-6, PII S1056871900001076
-
Lipinski CA. Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol Toxicol Meth. 2000;44:235-49. (Pubitemid 32239479)
-
(2000)
Journal of Pharmacological and Toxicological Methods
, vol.44
, Issue.1
, pp. 235-249
-
-
Lipinski, C.A.1
-
4
-
-
0036742053
-
Poor aqueous solubility - An industry wide problem in drug discovery
-
Lipinski CA. Poor aqueous solubility - An industry wide problem in drug discovery. Am Pharm Rev. 2002;5:82-5.
-
(2002)
Am Pharm Rev.
, vol.5
, pp. 82-85
-
-
Lipinski, C.A.1
-
5
-
-
55749093285
-
Prioritizing molecules based on physicochemical characteristics
-
Schroter C. Prioritizing molecules based on physicochemical characteristics. Am Pharm Rev. 2006;9:60-7.
-
(2006)
Am Pharm Rev.
, vol.9
, pp. 60-67
-
-
Schroter, C.1
-
6
-
-
0028948839
-
A theoretical basis for a biopharmaceutical drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon GL, Lennernas H, Shah VP, Crison JRA. A theoretical basis for a biopharmaceutical drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res. 1995;12:413-20.
-
(1995)
Pharm Res.
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.A.4
-
7
-
-
64649100465
-
Hydroxypropyl methylcellulose acetate succinate-based spray-dried dispersions: An overview
-
Friesen DT, Shanker R, Crew M, Smithey DT, Curatolo WJ, Nightingale JAS. Hydroxypropyl methylcellulose acetate succinate-based spray-dried dispersions: an overview. Mol Pharmaceutics. 2008;5(6):1003-19.
-
(2008)
Mol Pharmaceutics.
, vol.5
, Issue.6
, pp. 1003-1019
-
-
Friesen, D.T.1
Shanker, R.2
Crew, M.3
Smithey, D.T.4
Curatolo, W.J.5
Nightingale, J.A.S.6
-
8
-
-
67349158352
-
Spray drying from complex solvent systems broadens the applicability of Kollicoat IR as a carrier in the formulation of solid dispersions
-
Janssens S, Anné M, Rombaut P, Van den Mooter G. Spray drying from complex solvent systems broadens the applicability of Kollicoat IR as a carrier in the formulation of solid dispersions. Eur J Pharm Sci. 2009;35:241-8.
-
(2009)
Eur J Pharm Sci.
, vol.35
, pp. 241-248
-
-
Janssens, S.1
Anné, M.2
Rombaut, P.3
Van Den Mooter, G.4
-
9
-
-
34547128386
-
In vitro and in vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing griseofulvin
-
DOI 10.1016/j.ejps.2007.05.114, PII S0928098707002564
-
Ahmed IS, Aboul-Einien MH. In vitro and in vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing griseofulvin. Eur J Pharm Sci. 2007;32(1):58-68. (Pubitemid 47102190)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.32
, Issue.1
, pp. 58-68
-
-
Ahmed, I.S.1
Aboul-Einien, M.H.2
-
10
-
-
0036844753
-
Hydrogen bonding with adsorbent during storage governs drug dissolution from solid-dispersion granules
-
DOI 10.1023/A:1020905412654
-
Gupta MK, Tseng YC, Goldman D, Bogner RH. Hydrogen bonding with adsorbent during storage governs drug dissolution from solid-dispersion granules. Pharm Res. 2002;19(11):1663-72. (Pubitemid 35305518)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.11
, pp. 1663-1672
-
-
Gupta, M.K.1
Tseng, Y.-C.2
Goldman, D.3
Bogner, R.H.4
-
11
-
-
34548134519
-
Cyclodextrins as pharmaceutical solubilizers
-
DOI 10.1016/j.addr.2007.05.012, PII S0169409X07000841
-
Brewster ME, Loftsson T. Cyclodextrins as pharmaceutical solubilizers. Adv Drug Deliv Rev. 2007;59:645-66. (Pubitemid 47299263)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.7
, pp. 645-666
-
-
Brewster, M.E.1
Loftsson, T.2
-
12
-
-
35248822616
-
The utility of cyclodextrins for enhancing oral bioavailability
-
DOI 10.1016/j.jconrel.2007.07.018, PII S0168365907004129
-
Carrier RL, Miller LA, Ahmed I. The utility of cyclodextrins for enhancing oral bioavailability. J Controlled Release. 2007;123:78-99. (Pubitemid 47566400)
-
(2007)
Journal of Controlled Release
, vol.123
, Issue.2
, pp. 78-99
-
-
Carrier, R.L.1
Miller, L.A.2
Ahmed, I.3
-
13
-
-
34249790272
-
Application of nanoparticles in oral delivery of immediate release formulations
-
DOI 10.2174/157341307780619251
-
Kesisoglou F, Panmai S, Wu Y. Application of nanoparticles in oral delivery of immediate release formulations. Curr Nanosci. 2007;3:183-90. (Pubitemid 46845725)
-
(2007)
Current Nanoscience
, vol.3
, Issue.2
, pp. 183-190
-
-
Kesisoglou, F.1
Panmai, S.2
Wu, Y.3
-
14
-
-
41949100244
-
Drug nanoparticles: Formulating poorly water soluble compounds
-
Merisko-Liversidge EM, Liversidge GG. Drug nanoparticles: formulating poorly water soluble compounds. Toxicol Pathol. 2008;36:43-8.
-
(2008)
Toxicol Pathol.
, vol.36
, pp. 43-48
-
-
Merisko-Liversidge, E.M.1
Liversidge, G.G.2
-
15
-
-
0033805858
-
Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and "self-microemulsifying" drug delivery systems
-
Pouton CW. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and "self-microemulsifying" drug delivery systems. Eur J Pharm Sci. 2000;11:93-8.
-
(2000)
Eur J Pharm Sci.
, vol.11
, pp. 93-98
-
-
Pouton, C.W.1
-
16
-
-
1842684453
-
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs
-
DOI 10.1016/j.biopha.2004.02.001, PII S0753332204000319
-
Gursoy RN, Benita S. Self emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother. 2004;58:173-82. (Pubitemid 38479922)
-
(2004)
Biomedicine and Pharmacotherapy
, vol.58
, Issue.3
, pp. 173-182
-
-
Gursoy, R.N.1
Benita, S.2
-
17
-
-
79151476729
-
Universal wet-milling technique to prepare oral nanosuspension focused on discovery and preclinical animal studies-Development of particle design method
-
Niwa T, Miura S, Danjo K. Universal wet-milling technique to prepare oral nanosuspension focused on discovery and preclinical animal studies-Development of particle design method. Int J Pharm. 2011;405:218-27.
-
(2011)
Int J Pharm.
, vol.405
, pp. 218-227
-
-
Niwa, T.1
Miura, S.2
Danjo, K.3
-
19
-
-
74049124897
-
Spray drying technique. I: Hardware and process parameters
-
Cal K, Sollohub K. Spray drying technique. I: Hardware and process parameters. J Pharm Sci. 2010;99(2):575-86.
-
(2010)
J Pharm Sci.
, vol.99
, Issue.2
, pp. 575-586
-
-
Cal, K.1
Sollohub, K.2
-
20
-
-
74049124464
-
Spray drying technique: II. Current applications in pharmaceutical technology
-
Sollohub K, Cal K. Spray drying technique: II. Current applications in pharmaceutical technology. J Pharm Sci. 2010;99(2):587-97.
-
(2010)
J Pharm Sci.
, vol.99
, Issue.2
, pp. 587-597
-
-
Sollohub, K.1
Cal, K.2
-
21
-
-
9044235775
-
Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs
-
DOI 10.1023/A:1016051316815
-
Merisko-Liversidge E, Sarpotdar P, Bruno J, Hajj S, Wei L, Peltier N, et al. Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs. Pharm Res. 1996;13(2):272-8. (Pubitemid 26074194)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.2
, pp. 272-278
-
-
Merisko-Liversidge, E.1
Sarpotdar, P.2
Bruno, J.3
Hajj, S.4
Wei, L.5
Peltier, N.6
Rake, J.7
Shaw, J.M.8
Pugh, S.9
Polin, L.10
Jones, J.11
Corbett, T.12
Cooper, E.13
Liversidge, G.G.14
-
23
-
-
34249039982
-
Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling
-
DOI 10.1016/j.ijpharm.2007.02.005, PII S0378517307001573
-
Van Eerdenbrugh B, Froyen L, Martens JA, Blaton N, Augustijns P, Brewster M, et al. Characterization of physicochemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling. Int J Pharm. 2007;338:198-206. (Pubitemid 46779149)
-
(2007)
International Journal of Pharmaceutics
, vol.338
, Issue.1-2
, pp. 198-206
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Martens, J.A.3
Blaton, N.4
Augustijns, P.5
Brewster, M.6
Van Den Mooter, G.7
-
24
-
-
48849111481
-
Drying of crystalline drug nanosuspensions - The importance of surface hydrophobicity on dissolution behavior upon redispersion
-
Van Eerdenbrugh B, Froyen L, Van Humbeeck J, Martens JA, Augustijns P, Van den Mooter G. Drying of crystalline drug nanosuspensions - The importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur J Pharm Sci. 2008;35:127-35.
-
(2008)
Eur J Pharm Sci.
, vol.35
, pp. 127-135
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Van Humbeeck, J.3
Martens, J.A.4
Augustijns, P.5
Van Den Mooter, G.6
-
25
-
-
53849109902
-
Alternative matrix formers for nanosuspension solidification: Dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion
-
Van Eerdenbrugh B, Froyen L, Van Humbeeck J, Martens JA, Augustijns P, Van Den Mooter G. Alternative matrix formers for nanosuspension solidification: dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion. Eur J Pharm Sci. 2008;35:344-53.
-
(2008)
Eur J Pharm Sci.
, vol.35
, pp. 344-353
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Van Humbeeck, J.3
Martens, J.A.4
Augustijns, P.5
Van Den Mooter, G.6
-
26
-
-
0036176196
-
Production and characterization of a budesonide nanosuspension for pulmonary administration
-
DOI 10.1023/A:1014276917363
-
Jacobs C, Müller H. Production and characterization of a budesonide nanosuspension for pulmonary administration. Pharm Res. 2002;19(2):189-94. (Pubitemid 34165405)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.2
, pp. 189-194
-
-
Jacobs, C.1
Muller, R.H.2
-
27
-
-
33750089277
-
Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb-35440-3, a highly dosed poorly water-soluble weak base
-
DOI 10.1016/j.ejpb.2006.05.008, PII S0939641106001408
-
Hecq J, Deleers M, Fanara D, Vranckx H, Boulanger P, Le Lamer S, et al. Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb-35440-3, a highly dosed poorly water-soluble weak base. Eur J Pharm Biopharm. 2006;64:360-8. (Pubitemid 44585201)
-
(2006)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.64
, Issue.3
, pp. 360-368
-
-
Hecq, J.1
Deleers, M.2
Fanara, D.3
Vranckx, H.4
Boulanger, P.5
Le Lamer, S.6
Amighi, K.7
-
28
-
-
69749103682
-
Nanocrystal technology, drug delivery and clinical applications
-
Junghanns JAH, Müller RH. Nanocrystal technology, drug delivery and clinical applications. Inter J Nanomedicine. 2008;3(3):295-309.
-
(2008)
Inter J Nanomedicine.
, vol.3
, Issue.3
, pp. 295-309
-
-
Junghanns, J.A.H.1
Müller, R.H.2
-
29
-
-
70349694077
-
Nanoparticulation of poorly water soluble drugs using a wet-mill process and physicochemical properties of the nanopowders
-
Tanaka Y, Inkyo M, Yumoto R, Nagai J, Takano M, Nagata S. Nanoparticulation of poorly water soluble drugs using a wet-mill process and physicochemical properties of the nanopowders. Chem Pharm Bull. 2009;57(10):1050-7.
-
(2009)
Chem Pharm Bull.
, vol.57
, Issue.10
, pp. 1050-1057
-
-
Tanaka, Y.1
Inkyo, M.2
Yumoto, R.3
Nagai, J.4
Takano, M.5
Nagata, S.6
-
30
-
-
75449106350
-
Novel crystalline solid dispersion of tranilast with high photostability and improved oral bioavailability
-
Kawabata Y, Yamamoto K, Debari K, Onoue S, Yamada S. Novel crystalline solid dispersion of tranilast with high photostability and improved oral bioavailability. Eur J Pharm Sci. 2010;39(4):256-62.
-
(2010)
Eur J Pharm Sci.
, vol.39
, Issue.4
, pp. 256-262
-
-
Kawabata, Y.1
Yamamoto, K.2
Debari, K.3
Onoue, S.4
Yamada, S.5
-
31
-
-
78650830392
-
Design and characterization of nanocrystal formulations containing ezetimibe
-
Gulsun T, Gursoy RN, Oner L. Design and characterization of nanocrystal formulations containing ezetimibe. Chem Pharm Bull. 2011;59(1):41-5.
-
(2011)
Chem Pharm Bull.
, vol.59
, Issue.1
, pp. 41-45
-
-
Gulsun, T.1
Gursoy, R.N.2
Oner, L.3
-
32
-
-
33846496876
-
Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterisation
-
DOI 10.1016/j.ejps.2006.10.006, PII S0928098706003009
-
Tewa-Tagne P, Briançon S, Fessi H. Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterisation. Eur J Pharm Sci. 2007;30:124-35. (Pubitemid 46157175)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.30
, Issue.2
, pp. 124-135
-
-
Tewa-Tagne, P.1
Briancon, S.2
Fessi, H.3
-
33
-
-
0000424790
-
Solubility of pharmaceutical solids
-
Brittain HG, editor, New York: Marcel Dekker
-
Grant DJW, Brittain HG. Solubility of pharmaceutical solids. In: Brittain HG, editor. Physical characterization of pharmaceutical solids, drugs and the pharmaceutical sciences, vol. 70. New York: Marcel Dekker; 1995. p. 321-86.
-
(1995)
Physical Characterization of Pharmaceutical Solids, Drugs and the Pharmaceutical Sciences
, vol.70
, pp. 321-386
-
-
Grant, D.J.W.1
Brittain, H.G.2
-
34
-
-
39549094916
-
Formulation mechanism of colloidal nanoparticles obtained from probucol/PVP/SDS ternary ground mixture
-
Pongpeerapat A, Wanawongthai C, Tozuka Y, Moribe K, Yamamoto K. Formulation mechanism of colloidal nanoparticles obtained from probucol/PVP/SDS ternary ground mixture. Int J Pharm. 2008;352:309-16.
-
(2008)
Int J Pharm.
, vol.352
, pp. 309-316
-
-
Pongpeerapat, A.1
Wanawongthai, C.2
Tozuka, Y.3
Moribe, K.4
Yamamoto, K.5
-
35
-
-
45749129355
-
Morphology and surface states of colloidal probucol nanoparticles evaluated by atomic force microscopy
-
DOI 10.1248/cpb.56.878
-
Moribe K, Wanawongthai C, Shudo J, Higashi K, Yamamoto K. Morphology and surface states of colloidal probucol nanoparticles evaluated by atomic force microscopy. Chem Pharm Bull. 2008;56(6):878-80. (Pubitemid 351872265)
-
(2008)
Chemical and Pharmaceutical Bulletin
, vol.56
, Issue.6
, pp. 878-880
-
-
Moribe, K.1
Wanawongthai, C.2
Shudo, J.3
Higashi, K.4
Yamamoto, K.5
|