Novel small molecule activators of the Trk family of receptor tyrosine kinases

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 10, 2013, Pages 2213-2218

  Obianyo, Obiamaka ^a   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antidepressant; BDNF; Neurogenesis; Synthetic derivative; TrkB agonist

Indexed keywords

7,8 DIHYDROXYFLAVONE; AMIDE; AMITRIPTYLINE; ANTIBODY; DEOXYGEDUNIN; FLAVONE DERIVATIVE; GAMBOGIC ACID; PEPTIDE; PROTEIN TYROSINE KINASE; TROPOMYOSIN RELATED KINASE; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; DRUG MECHANISM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR BIOLOGY; MOLECULAR LIBRARY; NEUROLOGIC DISEASE; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SCREENING TEST; SIGNAL TRANSDUCTION;

ANTIDEPRESSANT; BDNF; NEUROGENESIS; SYNTHETIC DERIVATIVE; TRKB AGONIST;

AMITRIPTYLINE; ANIMALS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; FLAVONES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; NEURONS; PROTEIN BINDING; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; TROPOMYOSIN; XANTHONES;

EID: 84884498825     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2012.08.021     Document Type: Review

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