Isolation of xanthone and benzophenone derivatives from Cyclopia genistoides (L.) Vent. (honeybush) and their pro-apoptotic activity on synoviocytes from patients with rheumatoid arthritis

Fitoterapia

Volumn 90, Issue , 2013, Pages 199-208

  Kokotkiewicz, Adam ^a   Luczkiewicz, Maria ^a   Pawlowska, Justyna ^a   Luczkiewicz, Piotr ^a   Sowinski, Pawel ^b   Witkowski, Jacek ^a   Bryl, Ewa ^a   Bucinski, Adam ^c  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b GDANSK UNIVERSITY OF TECHNOLOGY   (Poland)

^c NICOLAUS COPERNICUS UNIVERSITY   (Poland)

Author keywords

Fibroblast like synovial cells; Iriflophenone 3 C glucoside; Isomangiferin; Mangiferin; Rheumatoid arthritis; Semi preparative HPLC

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONITRILE; BENZOPHENONE DERIVATIVE; GLUCOSIDE; HESPERIDIN; IRIFLOPHENONE 3 C BETA GLUCOSIDE; ISOMANGIFERIN; ISOMANGIFERIN (1,3,6,7 TETRAHYDROXYXANTHONE 4 C BETA GLUCOSIDE); LUTEOLIN; MACLURIN 3 C BETA GLUCOSIDE; MANGIFERIN; METHANOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WATER; XANTHONE DERIVATIVE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYCLOPIA GENISTOIDES; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; LIQUID LIQUID EXTRACTION; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE; PRECIPITATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

AA; ACTIVATOR PROTEIN 1; ADAMTS-4; ADJUVANT ARTHRITIS; AGGRECANASE-4; AP-1; CD3; CIA; CLUSTER OF DIFFERENTIATION 3; COLLAGEN-INDUCED ARTHRITIS; DAS28; DISEASE ACTIVITY SCORE OF 28 JOINTS; DMEM; DULBECCO'S MODIFIED EAGLE'S MEDIUM; FIBROBLAST-LIKE SYNOVIAL CELLS; IFN-Γ; IL-1Β; INTERFERON-GAMMA; INTERLEUKIN-1 BETA; IRIFLOPHENONE 3-C-Β-GLUCOSIDE; ISOMANGIFERIN; MANGIFERIN; MATRIX METALLOPROTEINASE; MMP; NONSTEROIDAL ANTI-INFLAMMATORY DRUGS; NSAIDS; PBS; PGE(2); PHOSPHATE BUFFERED SALINE; PROSTAGLANDIN E(2); RA; RHEUMATOID ARTHRITIS; SEMI-PREPARATIVE HPLC; SF; TNF-Α; TUMOR NECROSIS FACTOR-ALPHA;

ADULT; APOPTOSIS; ARTHRITIS, RHEUMATOID; FABACEAE; FEMALE; GLUCOSIDES; HESPERIDIN; HUMANS; MIDDLE AGED; MOLECULAR STRUCTURE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LECTINS; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA; XANTHONES;

EID: 84884493603     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.07.020     Document Type: Article

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