Alleviation of osteoarthritis by calycosin-7-O-β-d-glucopyranoside (CG) isolated from Astragali radix (AR) in rabbit osteoarthritis (OA) model

Osteoarthritis and Cartilage

Volumn 15, Issue 9, 2007, Pages 1086-1092

  Choi, S I ^a   Heo, T R ^a   Min, B H ^b   Cui, J H ^b   Choi, B H ^c   Park, S R ^c  

^a Inha University   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Inha University School of Medicine   (South Korea)

Author keywords

ACLMT; Astragali radix; Calycosin 7 O d glucopyranoside; Isoflavonoid; Osteoarthritis

Indexed keywords

ASTRAGALUS EXTRACT; CALYCOSIN 7 O BETA DEXTRO GLUCOPYRANOSIDE; DIMETHYL SULFOXIDE; GLYCOSAMINOGLYCAN; ISOFLAVONOID; PIROXICAM; PROSTAGLANDIN E2; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; ARTICULAR CARTILAGE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; HISTOPATHOLOGY; KNEE OSTEOARTHRITIS; MENISCECTOMY; NONHUMAN; OUTCOME ASSESSMENT; PLANT ROOT; PRIORITY JOURNAL; PROTEIN DETERMINATION; SYNOVIAL FLUID; TREATMENT DURATION;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTRAGALUS PLANT; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; GLUCOSIDES; GLYCOSAMINOGLYCANS; ISOFLAVONES; MENISCI, TIBIAL; OSTEOARTHRITIS; PIROXICAM; PROSTAGLANDINS; PROTEINS; RABBITS; SYNOVIAL FLUID;

EID: 34548583151     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2007.02.015     Document Type: Article

References (27)

1. Poole A.R. An introduction to the pathophysiology of osteoarthritis. Front Biosci 4 (1999) 662-670
2. Martin K., Lethbridge-Cejku M., Muller D.C., Elahi D., Andres R., Tobin J.D., et al. Metabolic correlates of obesity and radiographic features of knee osteoarthritis. Data from the Baltimore longitudinal study of aging. J Rheumatol 24 (1997) 702-707
3. Arner E.C., Pratta M.A., Trzaskos J.M., Decicco C.P., and Tortorella M.D. Generation and characterization of aggrecanase. J Biol Chem 274 (1999) 594-601
4. Hochberg M.C., and Dougados M. Pharmacological therapy of osteoarthritis. Best Pract Res Clin Rheumatol 15 (2001) 583-593
5. Akhud L., Quinet R.J., and Ishag S. Celecoxib-related renal papillary necrosis. Arch Intern Med 163 (2003) 114-115
6. Chang S.Y., and Howden C.W. Is no NSAID a good NSAID? Approaches to NSAID-associated upper gastrointestinal disease. Curr Gastroenterol Rep 6 (2004) 447-453
7. Kim E.J., Oh O.J., Lee S.K., and Yang K.S. Inhibitory effect of Astragali radix on COX-2 activity. Korean J Pharmacogn 32 (2001) 311-315
8. Choi S.I., Lee Y.M., and Heo T.R. Screening of hyaluronidase inhibitory and free radical scavenging activity in vitro of traditional herbal medicine extracts. Korean J Biotechnol Bioeng 18 (2003) 282-288
9. Choi S.I., Park S.R., and Heo T.R. Inhibitory effect of Astragali radix on matrix degradation in human articular cartilage. J Microbiol Biotechnol 15 (2005) 1258-1266
10. Lee Y.M., Choi S.I., Lee J.W., Jung S.M., Park S.M., and Heo T.R. Isolation of hyaluronidase inhibitory component from the roots of Astragalus membranaceus Bunge (Astragali radix). Korean J Food Sci Biotechnol 14 (2005) 263-267
11. Park S.R., Jang K.W., Park S.H., Choi H.S., Cui J.H., An H.J., et al. The effect of sonication on stimulated osteoarthritis. Part II: Alleviation of the osteoarthritis pathogenesis by 1 MHz ultrasound with simultaneous hyaluronate injection. Ultrasound Med Biol 31 (2005) 1559-1566
12. Emery P., Kong S.X., Ehrich E.W., Watson D.J., and Towheed T.E. Dose-effect relationships of nonsteroidal anti-inflammatory drugs: a literature review. Clin Ther 24 (2002) 1225-1291
13. Mankin H.J., Dorfman H., Lippiello L., and Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 53 (1971) 523-537
14. Gianyi M., Ikrenyi C., Fekete J., Ikrenyi K., and Kovach A.G.B. Ion concentrations in subcutaneous interstitial fluid: measured versus expected values. Am J Physiol 244 (1988) 513-519
15. Asari A., Miyauchi S., Matsuzaka S., Ito T., Kominami E., and Uchiyama Y. Molecular weight-dependent effects of hyaluronate on the arthritic synovium. Arch Histol Cytol 61 (1998) 125-135
16. Farndale R.W., Sayers C.A., and Barrett A.J. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res 9 (1982) 247-248
17. Shaw J., and Ramwell P. Separation, identification, and estimation of prostaglandins. Methods Biochem Anal 17 (1969) 325-371
18. Levick J.R. Synovial fluid. Determinants of volume turnover and material concentration. In: Kuettner K.E., Schleyerback R., Peyron J.G., and Hascall V.C. (Eds). Articular Cartilage and Osteoarthritis (1992), Raven, New York 529-541
19. Poole R., Ionescu M., Swan A., and Dieppe P.A. Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. J Clin Invest 94 (1994) 25-33
20. Elsaid K.A., Jay G.D., and Chichester C.O. Detection of collagen type II and proteoglycans in the synovial fluids of patients diagnosed with non-infectious knee joint synovitis indicates early damage to the articular cartilage matrix. Osteoarthritis Cartilage 11 (2003) 673-680
21. Siegle I., Klein T., Backman J.T., Saal J.G., Nusing R.M., and Fritz P. Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases. Arthritis Rheum 46 (2002) 1789-1803
22. Brenner S.S., Klotz U.B., Alscher D.M., Mais A., Lauer G., Schweer H., et al. Osteoarthritis of the knee - clinical assessments and inflammatory markers1. Osteoarthritis Cartilage 12 (2003) 469-475
23. Kang R.Y., Freire-Moar J., Sigal E., and Chu C.Q. Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis. Br J Rheumatol 35 (1996) 711-718
24. Amin A.R., Attur M., Patel R.N., Thakker G.D., Marshall P.J., Rediske J., et al. Superinduction of cyclooxygenase-2-activity in human osteoarthritis-affected cartilage: influence of nitric oxide. J Clin Invest 99 (1997) 1231-1237
25. Sanchez C.S., Mathy-Harter M., Deberg M.A., Ficheux H., Reginster J.Y.L., and Henrotin Y.E. Effects of rhein on human articular chondrocytes in alginate beads. Biochem Pharmacol 65 (2003) 377-388
26. Epinat J.C., and Gilmore T.D. Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway. Oncogene 18 (1999) 6896-6909
27. Makaro S.S. NF-κB as a therapeutic target in chronic inflammation: recent advances. Mol Med Today 6 (2000) 441-448