메뉴 건너뛰기




Volumn 35, Issue 1, 2013, Pages 139-146

7,3′-dimethoxy hesperetin inhibits inflammation by inducing synovial apoptosis in rats with adjuvant-induced arthritis

Author keywords

7,3 dimethoxy hesperetin; Adjuvant arthritis; Bcl 2; Inflammation; Synovial apoptosis

Indexed keywords

7,3' DIMETHOXY HESPERETIN; ANTIINFLAMMATORY AGENT; DNA; HESPERIDIN; INTERLEUKIN 1BETA; MESSENGER RNA; PLANT GLYCOSIDE; PROTEIN BAX; PROTEIN BCL 2; TRIPTERYGIUM GLYCOSIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HESPERETIN;

EID: 84869195059     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2012.723010     Document Type: Article
Times cited : (35)

References (39)
  • 1
    • 0025304539 scopus 로고
    • Rheumatoid arthritis. Pathophysiology and implications for therapy
    • Harris, E.D. Jr. Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990, 322, 1277-1289.
    • (1990) N Engl J Med , vol.322 , pp. 1277-1289
    • Harris Jr., E.D.1
  • 2
    • 39749153768 scopus 로고    scopus 로고
    • Effects of a-glucosylhesperidin, a bioactive food material, on collagen-induced arthritis in mice and rheumatoid arthritis in humans
    • Kometani, T., Fukuda, T., Kakuma, T., Kawaguchi, K., Tamura, W., Kumazawa, Y., Nagata, K. Effects of a-glucosylhesperidin, a bioactive food material, on collagen-induced arthritis in mice and rheumatoid arthritis in humans. Immunopharmacol Immunotoxicol 2008, 30, 117-134.
    • (2008) Immunopharmacol Immunotoxicol , vol.30 , pp. 117-134
    • Kometani, T.1    Fukuda, T.2    Kakuma, T.3    Kawaguchi, K.4    Tamura, W.5    Kumazawa, Y.6    Nagata, K.7
  • 3
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C.B. Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 4
    • 0035523087 scopus 로고    scopus 로고
    • Regulation of apoptosis and cell cycle activity in rheumatoid arthritis
    • Perlman, H., Pagliari, L.J., Volin, M.V. Regulation of apoptosis and cell cycle activity in rheumatoid arthritis. Curr Mol Med 2001, 1, 597-608.
    • (2001) Curr Mol Med , vol.1 , pp. 597-608
    • Perlman, H.1    Pagliari, L.J.2    Volin, M.V.3
  • 5
    • 33746225592 scopus 로고    scopus 로고
    • Molecular and cellular basis of rheumatoid joint destruction
    • Karouzakis, E., Neidhart, M., Gay, R.E., Gay, S. Molecular and cellular basis of rheumatoid joint destruction. Immunol Lett 2006, 106, 8-13.
    • (2006) Immunol Lett , vol.106 , pp. 8-13
    • Karouzakis, E.1    Neidhart, M.2    Gay, R.E.3    Gay, S.4
  • 6
    • 19544384628 scopus 로고    scopus 로고
    • Synovial activation in rheumatoid arthritis
    • Ospelt, C., Neidhart, M., Gay, R.E., Gay, S. Synovial activation in rheumatoid arthritis. Front Biosci 2004, 9, 2323-2334.
    • (2004) Front Biosci , vol.9 , pp. 2323-2334
    • Ospelt, C.1    Neidhart, M.2    Gay, R.E.3    Gay, S.4
  • 7
    • 0036636094 scopus 로고    scopus 로고
    • Apoptosis as a therapeutic tool in rheumatoid arthritis
    • Pope, R.M. Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat Rev Immunol 2002, 2, 527-535.
    • (2002) Nat Rev Immunol , vol.2 , pp. 527-535
    • Pope, R.M.1
  • 8
    • 13544273349 scopus 로고    scopus 로고
    • Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan- and Freund's complete adjuvant-induced rats
    • Jung, H.J., Nam, J.H., Choi, J., Lee, K.T., Park, H.J. Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan- and Freund's complete adjuvant-induced rats. J Ethnopharmacol 2005, 97, 359-367.
    • (2005) J Ethnopharmacol , vol.97 , pp. 359-367
    • Jung, H.J.1    Nam, J.H.2    Choi, J.3    Lee, K.T.4    Park, H.J.5
  • 9
    • 34250870129 scopus 로고    scopus 로고
    • Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats
    • Zheng, Y.Q., Wei, W., Zhu, L., Liu, J.X. Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats. Inflamm Res 2007, 56, 182-188.
    • (2007) Inflamm Res , vol.56 , pp. 182-188
    • Zheng, Y.Q.1    Wei, W.2    Zhu, L.3    Liu, J.X.4
  • 10
    • 78651069319 scopus 로고    scopus 로고
    • Inactivation of nuclear factor-kappaB by citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in Ramos cells
    • Nazari, M., Ghorbani, A., Hekmat-Doost, A., Jeddi-Tehrani, M., Zand, H. Inactivation of nuclear factor-kappaB by citrus flavanone hesperidin contributes to apoptosis and chemo-sensitizing effect in Ramos cells. Eur J Pharmacol 2011, 650, 526-533.
    • (2011) Eur J Pharmacol , vol.650 , pp. 526-533
    • Nazari, M.1    Ghorbani, A.2    Hekmat-Doost, A.3    Jeddi-Tehrani, M.4    Zand, H.5
  • 11
    • 33645993314 scopus 로고    scopus 로고
    • Suppression of collagen-induced arthritis by oral administration of the citrus flavonoid hesperidin
    • Kawaguchi, K., Maruyama, H., Kometani, T., Kumazawa, Y. Suppression of collagen-induced arthritis by oral administration of the citrus flavonoid hesperidin. Planta Med 2006, 72, 477-479.
    • (2006) Planta Med , vol.72 , pp. 477-479
    • Kawaguchi, K.1    Maruyama, H.2    Kometani, T.3    Kumazawa, Y.4
  • 12
    • 38949143942 scopus 로고    scopus 로고
    • Suppression of adjuvant arthritis by hesperidin in rats and its mechanisms
    • Li, R., Li, J., Cai, L., Hu, C.M., Zhang, L. Suppression of adjuvant arthritis by hesperidin in rats and its mechanisms. J Pharm Pharmacol 2008, 60, 221-228.
    • (2008) J Pharm Pharmacol , vol.60 , pp. 221-228
    • Li, R.1    Li, J.2    Cai, L.3    Hu, C.M.4    Zhang, L.5
  • 13
    • 0035667114 scopus 로고    scopus 로고
    • Chemistry and pharmacology of the Citrus bioflavonoid hesperidin
    • Garg, A., Garg, S., Zaneveld, L.J., Singla, A.K. Chemistry and pharmacology of the Citrus bioflavonoid hesperidin. Phytother Res 2001, 15, 655-669.
    • (2001) Phytother Res , vol.15 , pp. 655-669
    • Garg, A.1    Garg, S.2    Zaneveld, L.J.3    Singla, A.K.4
  • 15
    • 78649659778 scopus 로고    scopus 로고
    • 7,3'-dimethoxy hesperetin induces apoptosis of fibroblast-like synoviocytes in rats with adjuvant arthritis through caspase 3 activation
    • Li, R., Cai, L., Xie, X.F., Peng, L., Li, J. 7,3'-dimethoxy hesperetin induces apoptosis of fibroblast-like synoviocytes in rats with adjuvant arthritis through caspase 3 activation. Phytother Res 2010, 24, 1850-1856.
    • (2010) Phytother Res , vol.24 , pp. 1850-1856
    • Li, R.1    Cai, L.2    Xie, X.F.3    Peng, L.4    Li, J.5
  • 17
    • 8544270887 scopus 로고    scopus 로고
    • Therapeutic effects of glucosides of Cheanomeles speciosa on collageninduced arthritis in mice
    • Zhang, L.L., Wei, W., Yan, S.X., Hu, X.Y., Sun, W.Y. Therapeutic effects of glucosides of Cheanomeles speciosa on collageninduced arthritis in mice. Acta Pharmacol Sin 2004, 25, 1495-1501.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 1495-1501
    • Zhang, L.L.1    Wei, W.2    Yan, S.X.3    Hu, X.Y.4    Sun, W.Y.5
  • 18
    • 0031982941 scopus 로고    scopus 로고
    • Effects of Tripterygium wilfordii hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production
    • Tao, X., Schulze-Koops, H., Ma, L., Cai, J., Mao, Y., Lipsky, P.E. Effects of Tripterygium wilfordii hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production. Arthritis Rheum 1998, 41, 130-138.
    • (1998) Arthritis Rheum , vol.41 , pp. 130-138
    • Tao, X.1    Schulze-Koops, H.2    Ma, L.3    Cai, J.4    Mao, Y.5    Lipsky, P.E.6
  • 19
    • 78651407340 scopus 로고    scopus 로고
    • The expression change of ß-arrestins in fibroblast-like synoviocytes from rats with collageninduced arthritis and the effect of total glucosides of paeony
    • Wang, Q.T., Zhang, L.L., Wu, H.X., Wei, W. The expression change of ß-arrestins in fibroblast-like synoviocytes from rats with collageninduced arthritis and the effect of total glucosides of paeony. J Ethnopharmacol 2011, 133, 511-516.
    • (2011) J Ethnopharmacol , vol.133 , pp. 511-516
    • Wang, Q.T.1    Zhang, L.L.2    Wu, H.X.3    Wei, W.4
  • 20
    • 77958104221 scopus 로고    scopus 로고
    • Therapeutic effects of astragalus polysaccharides on inflammation and synovial apoptosis in rats with adjuvant-induced arthritis
    • Jiang, J.B., Qiu, J.D., Yang, L.H., He, J.P., Smith, G.W., Li, H.Q. Therapeutic effects of astragalus polysaccharides on inflammation and synovial apoptosis in rats with adjuvant-induced arthritis. Int J Rheum Dis 2010, 13, 396-405.
    • (2010) Int J Rheum Dis , vol.13 , pp. 396-405
    • Jiang, J.B.1    Qiu, J.D.2    Yang, L.H.3    He, J.P.4    Smith, G.W.5    Li, H.Q.6
  • 21
    • 0036710116 scopus 로고    scopus 로고
    • Effects and mechanisms of melatonin on inflammatory and immune responses of adjuvant arthritis rat
    • Chen, Q., Wei, W. Effects and mechanisms of melatonin on inflammatory and immune responses of adjuvant arthritis rat. Int Immunopharmacol 2002, 2, 1443-1449.
    • (2002) Int Immunopharmacol , vol.2 , pp. 1443-1449
    • Chen, Q.1    Wei, W.2
  • 23
    • 42649145901 scopus 로고    scopus 로고
    • Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2
    • Takahashi, K., Funata, N., Ikuta, F., Sato, S. Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2. J Neuroinflammation 2008, 5, 11.
    • (2008) J Neuroinflammation , vol.5 , pp. 11
    • Takahashi, K.1    Funata, N.2    Ikuta, F.3    Sato, S.4
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K.J., Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 79952435661 scopus 로고    scopus 로고
    • The novel phospho-non-steroidal antiinflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats
    • Huang, L., Mackenzie, G., Ouyang, N., Sun, Y., Xie, G., Johnson, F., Komninou, D., Rigas, B. The novel phospho-non-steroidal antiinflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats. Br J Pharmacol 2011, 162, 1521-1533.
    • (2011) Br J Pharmacol , vol.162 , pp. 1521-1533
    • Huang, L.1    Mackenzie, G.2    Ouyang, N.3    Sun, Y.4    Xie, G.5    Johnson, F.6    Komninou, D.7    Rigas, B.8
  • 26
    • 84857493478 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant properties of Sida rhombifolia stems and roots in adjuvant induced arthritic rats
    • Narendhirakannan, R.T., Limmy, T.P. Anti-inflammatory and antioxidant properties of Sida rhombifolia stems and roots in adjuvant induced arthritic rats. Immunopharmacol Immunotoxicol 2012, 34, 326-336.
    • (2012) Immunopharmacol Immunotoxicol , vol.34 , pp. 326-336
    • Narendhirakannan, R.T.1    Limmy, T.P.2
  • 27
    • 79961166368 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis
    • Ramadan, G., Al-Kahtani, M.A., El-Sayed, W.M. Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis. Inflammation 2011, 34, 291-301.
    • (2011) Inflammation , vol.34 , pp. 291-301
    • Ramadan, G.1    Al-Kahtani, M.A.2    El-Sayed, W.M.3
  • 28
    • 81855161863 scopus 로고    scopus 로고
    • Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats
    • Liu, M., Mao, W., Guan, H., Li, L., Wei, B., Li, P. Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats. Int Immunopharmacol 2011, 11, 2150-2158.
    • (2011) Int Immunopharmacol , vol.11 , pp. 2150-2158
    • Liu, M.1    Mao, W.2    Guan, H.3    Li, L.4    Wei, B.5    Li, P.6
  • 29
    • 0035989752 scopus 로고    scopus 로고
    • Cytokine inhibitors in the treatment of rheumatoid arthritis
    • Gabay, C. Cytokine inhibitors in the treatment of rheumatoid arthritis. Expert Opin Biol Ther 2002, 2, 135-149.
    • (2002) Expert Opin Biol Ther , vol.2 , pp. 135-149
    • Gabay, C.1
  • 31
    • 0347364681 scopus 로고    scopus 로고
    • Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice
    • Niki, Y., Yamada, H., Kikuchi, T., Toyama, Y., Matsumoto, H., Fujikawa, K., Tada, N. Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice. J Immunol 2004, 172, 577-584.
    • (2004) J Immunol , vol.172 , pp. 577-584
    • Niki, Y.1    Yamada, H.2    Kikuchi, T.3    Toyama, Y.4    Matsumoto, H.5    Fujikawa, K.6    Tada, N.7
  • 32
    • 25444484909 scopus 로고    scopus 로고
    • Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis
    • Bokarewa, M., Lindblad, S., Bokarew, D., Tarkowski, A. Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis. Arthritis Res Ther 2005, 7, R349-R358.
    • (2005) Arthritis Res Ther , vol.7
    • Bokarewa, M.1    Lindblad, S.2    Bokarew, D.3    Tarkowski, A.4
  • 33
    • 52049117698 scopus 로고    scopus 로고
    • Mechanism of fibroblast-like synoviocyte apoptosis induced by recombinant human endostatin in rats with adjuvant arthritis
    • Huang, X.Y., Chen, F.H., Li, J., Xia, L.J., Liu, Y.J., Zhang, X.M., Yuan, F.L. Mechanism of fibroblast-like synoviocyte apoptosis induced by recombinant human endostatin in rats with adjuvant arthritis. Anat Rec (Hoboken) 2008, 291, 1029-1037.
    • (2008) Anat Rec (Hoboken , vol.291 , pp. 1029-1037
    • Huang, X.Y.1    Chen, F.H.2    Li, J.3    Xia, L.J.4    Liu, Y.J.5    Zhang, X.M.6    Yuan, F.L.7
  • 34
    • 33845249224 scopus 로고    scopus 로고
    • Induction of cell apoptosis in 3T3-L1 preadipocytes by flavonoids is associated with their antioxidant activity
    • Hsu, C.L., Yen, G.C. Induction of cell apoptosis in 3T3-L1 preadipocytes by flavonoids is associated with their antioxidant activity. Mol Nutr Food Res 2006, 50, 1072-1079.
    • (2006) Mol Nutr Food Res , vol.50 , pp. 1072-1079
    • Hsu, C.L.1    Yen, G.C.2
  • 36
    • 0032568208 scopus 로고    scopus 로고
    • Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents
    • Kobayashi, T., Ruan, S., Clodi, K., Kliche, K.O., Shiku, H., Andreeff, M., Zhang, W. Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents. Oncogene 1998, 16, 1587-1591.
    • (1998) Oncogene , vol.16 , pp. 1587-1591
    • Kobayashi, T.1    Ruan, S.2    Clodi, K.3    Kliche, K.O.4    Shiku, H.5    Andreeff, M.6    Zhang, W.7
  • 37
    • 0343091223 scopus 로고    scopus 로고
    • Bcl-2 expression in synovial fibroblasts is essential for maintaining mitochondrial homeostasis and cell viability
    • Perlman, H., Georganas, C., Pagliari, L.J., Koch, A.E., Haines, K. 3rd, Pope, R.M. Bcl-2 expression in synovial fibroblasts is essential for maintaining mitochondrial homeostasis and cell viability. J Immunol 2000, 164, 5227-5235.
    • (2000) J Immunol , vol.164 , pp. 5227-5235
    • Perlman, H.1    Georganas, C.2    Pagliari, L.J.3    Koch, A.E.4    Haines III, K.5    Pope, R.M.6
  • 39
    • 0032546450 scopus 로고    scopus 로고
    • Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratio
    • Fukamachi, Y., Karasaki, Y., Sugiura, T., Itoh, H., Abe, T., Yamamura, K., Higashi, K. Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratio. Biochem Biophys Res Commun 1998, 246, 364-369.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 364-369
    • Fukamachi, Y.1    Karasaki, Y.2    Sugiura, T.3    Itoh, H.4    Abe, T.5    Yamamura, K.6    Higashi, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.