Isolation of isomangiferin from honeybush (Cyclopia subternata) using high-speed counter-current chromatography and high-performance liquid chromatography

Journal of Chromatography A

Volumn 1216, Issue 19, 2009, Pages 4282-4289

  de Beer, Dalene ^a   Jerz, Gerold ^b   Joubert, Elizabeth ^a,c   Wray, Victor ^d   Winterhalter, Peter ^b  

^a ARC INFRUITEC NIETVOORBIJ   (South Africa)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Counter current chromatography; Cyclopia subternata; Fabaceae; Isomangiferin; Mangiferin; NMR spectroscopy; Xanthones

Indexed keywords

COUNTER-CURRENT CHROMATOGRAPHY; CYCLOPIA SUBTERNATA; FABACEAE; ISOMANGIFERIN; MANGIFERIN; NMR SPECTROSCOPY; XANTHONES;

ACETONITRILE; BODY FLUIDS; BUBBLES (IN FLUIDS); CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; ESTERS; ETHERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC SOLVENTS; PHENOLS;

SOLVENT EXTRACTION;

ACETIC ACID ETHYL ESTER; COUMARIC ACID; ERIOCITRIN; HESPERIDIN; ISOMANGIFERIN; LUTEOLIN; MANGIFERIN; METHANOL; PHENOL DERIVATIVE; SCOLYMOSIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COUNTER CURRENT CHROMATOGRAPHY; CYCLOPIA SUBTERNATA; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; CYCLOPIA PLANT; METHANOL; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT EXTRACTS; XANTHONES;

CYCLOPIA SUBTERNATA; FABACEAE;

EID: 64549091054     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.02.056     Document Type: Article

References (21)

1. Pinto M.M.M., Sousa M.E., and Nascimento M.S.J. Curr. Med. Chem. 12 (2005) 2517
2. Núňez Sellés A.J., Vélez Castro H.T., Agüero-Agüero J., González-González J., Naddeo F., De Simone F., and Rastrelli L. J. Agric. Food Chem. 50 (2002) 762
3. Joubert E., Gelderblom W.C.A., Louw A., and de Beer D. J. Ethnopharmacol. 119 (2008) 376
4. Ferreira D., Kamara B.I., Brandt E.V., and Joubert E. J. Agric Food Chem. 46 (1998) 3406
5. Joubert E., Otto F., Grüner S., and Weinreich B. Eur. Food Res. Technol. 216 (2003) 270
6. Joubert E., Richards E.S., van der Merwe J.D., de Beer D., Manley M., and Gelderblom W.C.A. J. Agric. Food Chem. 56 (2008) 954
7. Ito Y. J. Chromatogr. A 1065 (2005) 145
8. Fujita M., and Inoue T. Chem. Pharm. Bull. 30 (1982) 2342
9. Catalano S., Luschi S., Flamini G., Cioni P.L., Nieri E.M., and Morelli I. Phytochemistry 42 (1996) 1605
10. Sun Q., Sun A., and Liu R. J. Chromatogr. A 1104 (2006) 69
11. Zhou T., Zhu Z., Wang C., Fan G., Peng J., Chai Y., and Wu Y. J. Pharm. Biomed. Anal. 44 (2007) 96
12. Ito Y., and Conway W.D. High-Speed Countercurrent Chromatography (1996), Wiley, New York
13. Stahl E., and Kaltenbach U. J. Chromatogr. 5 (1961) 351
14. Kamara B.I., Brandt E.V., Ferreira D., and Joubert E. J. Agric. Food Chem. 51 (2003) 3874
15. Kamara B.I., Brand D.J., Brandt E.V., and Joubert E. J. Agric. Food Chem. 52 (2004) 5391
16. Otsuka H. Chem. Pharm. Bull. 47 (1999) 962
17. Gutzeit D., Winterhalter P., and Jerz G. J. Chromatogr. A 1172 (2007) 40
18. Suryawanshi S., Mehrotra N., Asthana R.K., and Gupta R.C. Rapid Commun. Mass Spectrom. 20 (2006) 3761
19. Rath G., Touré A., Nianga M., Wolfender J.-L., and Hostettmann K. Chromatographia 41 (1995) 332
20. Schieber A., Berardini N., and Carle R. J. Agric. Food Chem. 51 (2003) 5006
21. Frahm A.W., and Chaudhuri R.K. Tetrahedron Lett. 35 (1979) 2035