Isoorientin protects BRL-3A rat liver cell against hydrogen peroxide-induced apoptosis by inhibiting mitochondrial dysfunction, inactivating MAPKs, activating Akt and scavenging ROS and NO

Biomedicine and Aging Pathology

Volumn 3, Issue 3, 2013, Pages 153-159

  Yuan, Li ^a   Ren, Xiaomeng ^a   Wu, Yuchen ^a   Wang, Jing ^a   Xiao, Haifang ^a   Liu, Xuebo ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Akt; Apoptosis; Isoorientin; MAPK kinases; Mitochondrial dysfunction; Oxidative damage

Indexed keywords

CASPASE 3; CATALASE; CYTOCHROME C; HYDROGEN PEROXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOORIENTIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN BAX; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY TEST; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; LIVER CELL; LIVER PROTECTION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 84884415645     PISSN: 22105220     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomag.2013.06.004     Document Type: Article

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