메뉴 건너뛰기




Volumn 389, Issue 1, 2009, Pages 105-111

Propofol protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via Akt activation and Bcl-2 up-regulation

Author keywords

Akt; Apoptosis; Bcl 2; H9c2 cells; Oxidative stress; Propofol

Indexed keywords

HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROPOFOL; PROTEIN BCL 2; PROTEIN KINASE B; WORTMANNIN;

EID: 70349124966     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.08.097     Document Type: Article
Times cited : (96)

References (26)
  • 1
    • 0030051019 scopus 로고    scopus 로고
    • Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart
    • Kokita N., and Hara A. Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart. Anesthesiology 84 (1996) 117-127
    • (1996) Anesthesiology , vol.84 , pp. 117-127
    • Kokita, N.1    Hara, A.2
  • 2
    • 0038143236 scopus 로고    scopus 로고
    • Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity
    • Xia Z., Godin D.V., and Ansley D.M. Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity. Cardiovasc. Res. 59 (2003) 113-121
    • (2003) Cardiovasc. Res. , vol.59 , pp. 113-121
    • Xia, Z.1    Godin, D.V.2    Ansley, D.M.3
  • 3
    • 0037247879 scopus 로고    scopus 로고
    • Dose-dependent protection of cardiac function by propofol during ischemia and early reperfusion in rats: effects on 15-F2t-isoprostane formation
    • Xia Z., Godin D.V., Chang T.K., and Ansley D.M. Dose-dependent protection of cardiac function by propofol during ischemia and early reperfusion in rats: effects on 15-F2t-isoprostane formation. Can. J. Physiol. Pharmacol. 81 (2003) 14-21
    • (2003) Can. J. Physiol. Pharmacol. , vol.81 , pp. 14-21
    • Xia, Z.1    Godin, D.V.2    Chang, T.K.3    Ansley, D.M.4
  • 5
    • 34548008730 scopus 로고    scopus 로고
    • Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection
    • Hausenloy D.J., and Yellon D.M. Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail. Rev. 12 (2007) 217-234
    • (2007) Heart Fail. Rev. , vol.12 , pp. 217-234
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 6
    • 26444448463 scopus 로고    scopus 로고
    • The survival kinases Akt and Pim as potential pharmacological targets
    • Amaravadi R., and Thompson C.B. The survival kinases Akt and Pim as potential pharmacological targets. J. Clin. Invest. 115 (2005) 2618-2624
    • (2005) J. Clin. Invest. , vol.115 , pp. 2618-2624
    • Amaravadi, R.1    Thompson, C.B.2
  • 7
    • 11144253483 scopus 로고    scopus 로고
    • Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt
    • Matsui T., and Rosenzweig A. Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt. J. Mol. Cell Cardiol. 38 (2005) 63-71
    • (2005) J. Mol. Cell Cardiol. , vol.38 , pp. 63-71
    • Matsui, T.1    Rosenzweig, A.2
  • 8
    • 19044379949 scopus 로고    scopus 로고
    • Propofol dose-dependently reduces tumor necrosis factor-alpha-induced human umbilical vein endothelial cell apoptosis: effects on Bcl-2 and Bax expression and nitric oxide generation
    • Luo T., Xia Z., Ansley D.M., Ouyang J., Granville D.J., Li Y., Xia Z.Y., Zhou Q.S., and Liu X.Y. Propofol dose-dependently reduces tumor necrosis factor-alpha-induced human umbilical vein endothelial cell apoptosis: effects on Bcl-2 and Bax expression and nitric oxide generation. Anesth. Analg. 100 (2005) 1653-1659
    • (2005) Anesth. Analg. , vol.100 , pp. 1653-1659
    • Luo, T.1    Xia, Z.2    Ansley, D.M.3    Ouyang, J.4    Granville, D.J.5    Li, Y.6    Xia, Z.Y.7    Zhou, Q.S.8    Liu, X.Y.9
  • 9
    • 34748817473 scopus 로고    scopus 로고
    • Propofol reduces apoptosis and up-regulates endothelial nitric oxide synthase protein expression in hydrogen peroxide-stimulated human umbilical vein endothelial cells
    • (table of contents)
    • Wang B., Luo T., Chen D., and Ansley D.M. Propofol reduces apoptosis and up-regulates endothelial nitric oxide synthase protein expression in hydrogen peroxide-stimulated human umbilical vein endothelial cells. Anesth. Analg. 105 (2007) 1027-1033 (table of contents)
    • (2007) Anesth. Analg. , vol.105 , pp. 1027-1033
    • Wang, B.1    Luo, T.2    Chen, D.3    Ansley, D.M.4
  • 11
    • 41549085286 scopus 로고    scopus 로고
    • Propofol attenuation of hydrogen peroxide-mediated oxidative stress and apoptosis in cultured cardiomyocytes involves haeme oxygenase-1
    • Xu J.J., and Wang Y.L. Propofol attenuation of hydrogen peroxide-mediated oxidative stress and apoptosis in cultured cardiomyocytes involves haeme oxygenase-1. Eur. J. Anaesthesiol. 25 (2008) 395-402
    • (2008) Eur. J. Anaesthesiol. , vol.25 , pp. 395-402
    • Xu, J.J.1    Wang, Y.L.2
  • 12
    • 35349023691 scopus 로고    scopus 로고
    • Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway
    • Pachori A.S., Smith A., McDonald P., Zhang L., Dzau V.J., and Melo L.G. Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway. J. Mol. Cell Cardiol. 43 (2007) 580-592
    • (2007) J. Mol. Cell Cardiol. , vol.43 , pp. 580-592
    • Pachori, A.S.1    Smith, A.2    McDonald, P.3    Zhang, L.4    Dzau, V.J.5    Melo, L.G.6
  • 13
    • 0025791965 scopus 로고
    • Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart
    • Hescheler J., Meyer R., Plant S., Krautwurst D., Rosenthal W., and Schultz G. Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart. Circ. Res. 69 (1991) 1476-1486
    • (1991) Circ. Res. , vol.69 , pp. 1476-1486
    • Hescheler, J.1    Meyer, R.2    Plant, S.3    Krautwurst, D.4    Rosenthal, W.5    Schultz, G.6
  • 16
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 17
    • 34347378009 scopus 로고    scopus 로고
    • The effects of propofol on neutrophil function, lipid peroxidation and inflammatory response during elective coronary artery bypass grafting in patients with impaired ventricular function
    • Corcoran T.B., Engel A., Sakamoto H., O'Shea A., O'Callaghan-Enright S., and Shorten G.D. The effects of propofol on neutrophil function, lipid peroxidation and inflammatory response during elective coronary artery bypass grafting in patients with impaired ventricular function. Br. J. Anaesth. 97 (2006) 825-831
    • (2006) Br. J. Anaesth. , vol.97 , pp. 825-831
    • Corcoran, T.B.1    Engel, A.2    Sakamoto, H.3    O'Shea, A.4    O'Callaghan-Enright, S.5    Shorten, G.D.6
  • 18
    • 0033969964 scopus 로고    scopus 로고
    • Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition
    • Javadov S.A., Lim K.H., Kerr P.M., Suleiman M.S., Angelini G.D., and Halestrap A.P. Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition. Cardiovasc. Res. 45 (2000) 360-369
    • (2000) Cardiovasc. Res. , vol.45 , pp. 360-369
    • Javadov, S.A.1    Lim, K.H.2    Kerr, P.M.3    Suleiman, M.S.4    Angelini, G.D.5    Halestrap, A.P.6
  • 19
    • 18744380649 scopus 로고    scopus 로고
    • Propofol increases pulmonary artery smooth muscle myofilament calcium sensitivity: role of protein kinase C
    • Tanaka S., Kanaya N., Homma Y., Damron D.S., and Murray P.A. Propofol increases pulmonary artery smooth muscle myofilament calcium sensitivity: role of protein kinase C. Anesthesiology 97 (2002) 1557-1566
    • (2002) Anesthesiology , vol.97 , pp. 1557-1566
    • Tanaka, S.1    Kanaya, N.2    Homma, Y.3    Damron, D.S.4    Murray, P.A.5
  • 20
    • 33646801176 scopus 로고    scopus 로고
    • 2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes
    • 2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes. Anesthesiology 104 (2006) 978-987
    • (2006) Anesthesiology , vol.104 , pp. 978-987
    • Wickley, P.J.1    Shiga, T.2    Murray, P.A.3    Damron, D.S.4
  • 22
    • 0035970041 scopus 로고    scopus 로고
    • Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction
    • Negoro S., Oh H., Tone E., Kunisada K., Fujio Y., Walsh K., Kishimoto T., and Yamauchi-Takihara K. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation 103 (2001) 555-561
    • (2001) Circulation , vol.103 , pp. 555-561
    • Negoro, S.1    Oh, H.2    Tone, E.3    Kunisada, K.4    Fujio, Y.5    Walsh, K.6    Kishimoto, T.7    Yamauchi-Takihara, K.8
  • 23
    • 33745199637 scopus 로고    scopus 로고
    • Akt regulates basal and induced processing of NF-kappaB2 (p100) to p52
    • Gustin J.A., Korgaonkar C.K., Pincheira R., Li Q., and Donner D.B. Akt regulates basal and induced processing of NF-kappaB2 (p100) to p52. J. Biol. Chem. 281 (2006) 16473-16481
    • (2006) J. Biol. Chem. , vol.281 , pp. 16473-16481
    • Gustin, J.A.1    Korgaonkar, C.K.2    Pincheira, R.3    Li, Q.4    Donner, D.B.5
  • 24
    • 29444453188 scopus 로고    scopus 로고
    • The anti-death machinery in IKK/NF-kappaB signaling
    • Luo J.L., Kamata H., and Karin M. The anti-death machinery in IKK/NF-kappaB signaling. J. Clin. Immunol. 25 (2005) 541-550
    • (2005) J. Clin. Immunol. , vol.25 , pp. 541-550
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 25
    • 63349089932 scopus 로고    scopus 로고
    • Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?
    • Lecour S. Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?. J. Mol. Cell Cardiol. 46 (2009) 607-609
    • (2009) J. Mol. Cell Cardiol. , vol.46 , pp. 607-609
    • Lecour, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.