Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity

Innate Immunity

Volumn 19, Issue 5, 2013, Pages 493-503

  Rubino, Stephen J ^a   Magalhaes, Joao G ^a   Philpott, Dana ^a   Bahr, George M ^b   Blanot, Didier ^c   Girardin, Stephen E ^a,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF BALAMAND   (Lebanon)

^c CNRS   (France)

^d INSTITUT CURIE   (France)

Author keywords

adjuvant; inflammation; innate immunity; muramyl dipeptide; muramyl peptides; Nod2

Indexed keywords

AMINO ACID; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; LUCIFERASE; METHYL GROUP; MURAMYL PEPTIDE;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL WALL; BONE MARROW; CONTROLLED STUDY; CROHN DISEASE; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS;

ADJUVANT; INFLAMMATION; INNATE IMMUNITY; MURAMYL DIPEPTIDE; MURAMYL PEPTIDES; NOD2;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ANIMALS; CROHN DISEASE; DENDRITIC CELLS; ENZYME ACTIVATION; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; INTERLEUKIN-6; MACROPHAGES; METHYLATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, GENETIC; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION; TRANSGENES;

EID: 84884384960     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425912471691     Document Type: Article

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