Chondroprotective supplementation promotes the mechanical properties of injectable scaffold for human nucleus pulposus tissue engineering

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 29, Issue , 2014, Pages 56-67

  Foss, Berit L ^a   Maxwell, Thomas W ^b   Deng, Ying ^a  

^a University of South Dakota   (United States)

^b University of Miami College of Engineering   (United States)

Author keywords

Alginate hydrogel; Confined compression; Nucleus pulposus; Tissue engineering

Indexed keywords

ALGINATE HYDROGELS; BIOMECHANICAL EVALUATION; BIOMECHANICAL FUNCTIONS; CONFINED COMPRESSION; NUCLEUS PULPOSUS; NUCLEUS PULPOSUS TISSUE ENGINEERINGS; TISSUE-ENGINEERED CONSTRUCTS; TISSUE-ENGINEERED SCAFFOLDS;

BIOMECHANICS; CELL PROLIFERATION; MECHANICAL PROPERTIES; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

ALGINIC ACID; CALCIUM CHLORIDE; CHONDROITIN SULFATE; CHONDROPROTECTIVE AGENT; COLLAGEN TYPE 2; GLUCOSAMINE; GLYCOSAMINOGLYCAN; TISSUE SCAFFOLD;

ARTICLE; CELL ENCAPSULATION; CELL PROLIFERATION; CELL VIABILITY; CHONDROPROTECTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; INJECTION; INTERVERTEBRAL DISK DEGENERATION; MOLECULAR MECHANICS; NANOFABRICATION; NUCLEUS PULPOSUS; PRIORITY JOURNAL; SUPPLEMENTATION; TISSUE ENGINEERING; WATER CONTENT;

ALGINATE HYDROGEL; CONFINED COMPRESSION; NUCLEUS PULPOSUS; TISSUE ENGINEERING;

BIOCOMPATIBLE MATERIALS; BIOMECHANICAL PHENOMENA; CALCIUM CHLORIDE; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN TYPE II; GLYCOSAMINOGLYCANS; HUMANS; HYDROGELS; INJECTIONS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MECHANICAL PROCESSES; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WATER;

EID: 84884380817     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2013.08.020     Document Type: Article

References (53)

1. Amin A.K., Huntley J.S., et al. Chondrocyte death in mechanically injured articular cartilage--the influence of extracellular calcium. Journal of Orthopaedic Research 2009, 27(6):778-784.
2. Augst A.D., Kong H.J., et al. Alginate hydrogels as biomaterials. Macromolecular Bioscience 2006, 6(8):623-633.
3. Borges A.C., Eyholzer C., et al. Nanofibrillated cellulose composite hydrogel for the replacement of the nucleus pulposus. Acta Biomaterialia 2011, 7(9):3412-3421.
4. Bron J.L., Vonk L.A., et al. Engineering alginate for intervertebral disc repair. Journal of the Mechanical Behavior of Biomedical Materials 2011, 4(7):1196-1205.
5. Calderon L., Collin E., et al. Type II collagen-hyaluronan hydrogel-A step towards a scaffold for intervertebral disc tissue engineering. Eur Cell Mater 2010, 20:134-148.
6. Chan B.P., Leong K.W. Scaffolding in tissue engineering: general approaches and tissue-specific considerations. European Cells and Materials 2008, 17(Suppl 4):467-479.
7. Chen J., Yan W., et al. Molecular phenotypes of notochordal cells purified from immature nucleus pulposus. European Spine Journal 2006, 15(Suppl 3):S303-311.
8. Chondrex, I., 2012. Type II Collagen Detection Kit Protocol. I. Chondrex.
9. Chou A.I., Akintoye S.O., et al. Photo-crosslinked alginate hydrogels support enhanced matrix accumulation by nucleus pulposus cells in vivo. Osteoarthritis and Cartilage 2009, 17(10):1377-1384.
10. Chou A.I., Nicoll S.B. Characterization of photocrosslinked alginate hydrogels for nucleus pulposus cell encapsulation. Journal of Biomedical Materials Research A 2009, 91(1):187-194.
11. Chung C., Erickson I.E., et al. Differential behavior of auricular and articular chondrocytes in hyaluronic acid hydrogels. Tissue Engineering, Part A 2008, 14(7):1121-1131.
12. Cloyd J.M., Malhotra N.R., et al. Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds. European Spine Journal 2007, 16(11):1892-1898.
13. Cohen J., Zaleski K.L., et al. Survival of porcine mesenchymal stem cells over the alginate recovered cellular method. Journal of Biomedical Materials Research A 2011, 96(1):93-99.
14. Collin E.C., Grad S., et al. An injectable vehicle for nucleus pulposus cell-based therapy. Biomaterials 2011, 32(11):2862-2870.
15. Colombini A., Lombardi G., et al. Pathophysiology of the human intervertebral disc. International Journal of Biochemistry and Cell Biology 2008, 40(5):837-842.
16. Cong L., Pang H., et al. Association between the expression of aggrecan and the distribution of aggrecan gene variable number of tandem repeats with symptomatic lumbar disc herniation in Chinese Han of Northern China. Spine (Phila Pa 1976) 2010, 35(14):1371-1376.
17. Enobakhare B.O., Bader D.L., et al. Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue. Analytical Biochemistry 1996, 243(1):189-191.
18. Gorensek M., Jaksimovic C., et al. Nucleus pulposus repair with cultured autologous elastic cartilage derived chondrocytes. Cellular and Molecular Biology Letters 2004, 9(2):363-373.
19. Grunder T., Gaissmaier C., et al. Bone morphogenetic protein (BMP)-2 enhances the expression of type II collagen and aggrecan in chondrocytes embedded in alginate beads. Osteoarthritis and Cartilage 2004, 12(7):559-567.
20. Halloran D.O., Grad S., et al. An injectable cross-linked scaffold for nucleus pulposus regeneration. Biomaterials 2008, 29(4):438-447.
21. Hunt, N.C., 2010. An alginate hydrogel matrix for the localised delivery of a fibroblast/ keratinocyte co-culture to expedite wound healing. Ph.D., University of Birmingham.
22. Hunt N.C., Smith A.M., et al. Encapsulation of fibroblasts causes accelerated alginate hydrogel degradation. Acta Biomaterialia 2010, 6(9):3649-3656.
23. Iatridis J.C., Setton L.A., et al. The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear. Journal of Biomechanics 1997, 30(10):1005-1013.
24. Iatridis J.C., Weidenbaum M., et al. Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc. Spine (Phila Pa 1976) 1996, 21(10):1174-1184.
25. Jerosch J. Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially omega-3 fatty acids. International Journal of Rheumatology 2011, 2011:969012.
26. Johannessen W., Elliott D.M. Effects of degeneration on the biphasic material properties of human nucleus pulposus in confined compression. Spine (Phila Pa 1976) 2005, 30(24):E724-729.
27. Jones K.H., Senft J.A. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. Journal of Histochemistry and Cytochemistry 1985, 33(1):77-79.
28. Jurvelin J.S., Buschmann M.D., et al. Optical and mechanical determination of Poisson's ratio of adult bovine humeral articular cartilage. Journal of Biomechanics 1997, 30(3):235-241.
29. Klein R.G., Eek B.C., et al. Biochemical injection treatment for discogenic low back pain: a pilot study. Spine Journal 2003, 3(3):220-226.
30. Kobayashi S., Baba H., Takeno K., Miyazaki T., Meir A., Urban J. Physical limitations to tissue engineering of intervertabral disc cells. Tissue Engineering 2010, 25.
31. Lopiz-Morales Y., Abarrategi A., et al. In vivo comparison of the effects of rhBMP-2 and rhBMP-4 in osteochondral tissue regeneration. European Cells and Materials 2010, 20:367-378.
32. Lyons G., Eisenstein S.M., et al. Biochemical changes in intervertebral disc degeneration. Biochimica et Biophysica Acta 1981, 673(4):443-453.
33. Massey C.J., van Donkelaar C.C., et al. Effects of aging and degeneration on the human intervertebral disc during the diurnal cycle: a finite element study. Journal of Orthopaedic Research 2012, 30(1):122-128.
34. Masuda K., Imai Y., et al. Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model. Spine (Phila Pa 1976) 2006, 31(7):742-754.
35. Mauth C., Bono E., et al. Cell-seeded polyurethane-fibrin structures--a possible system for intervertebral disc regeneration. European Cells and Materials 2009, 18:27-38. (discussion 38-29).
36. Mavrogonatou E., Kletsas D. The effect of glucosamine sulfate on the proliferative potential and glycosaminoglycan synthesis of nucleus pulposus intervertebral disc cells. Spine (Phila Pa 1976) 2013, 38(4):308-314.
37. Mouw J.K., Case N.D., et al. Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering. Osteoarthritis and Cartilage 2005, 13(9):828-836.
38. Nerurkar N.L., Elliott D.M., et al. Mechanical design criteria for intervertebral disc tissue engineering. Journal of Biomechanics 2010, 43(6):1017-1030.
39. Nesti L.J., Li W.J., et al. Intervertebral disc tissue engineering using a novel hyaluronic acid-nanofibrous scaffold (HANFS) amalgam. Tissue Engineering, Part A 2008, 14(9):1527-1537.
40. Nunamaker E.A., Purcell E.K., et al. In vivo stability and biocompatibility of implanted calcium alginate disks. Journal of Biomedical Materials Research Part A 2007, 83(4):1128-1137.
41. Paige K.T., Cima L.G., et al. De novo cartilage generation using calcium alginate-chondrocyte constructs. Plastic and Reconstructive Surgery 1996, 97(1):168-178. (discussion 179-180).
42. Reginster J.Y., Deroisy R., et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 2001, 357(9252):251-256.
43. Singh K., Masuda K., et al. Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc. Spine (Phila Pa 1976) 2009, 34(1):10-16.
44. Sive J.I., Baird P., et al. Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs. Molecular Pathology 2002, 55(2):91-97.
45. Skaalure S.C., Milligan I.L., et al. Age impacts extracellular matrix metabolism in chondrocytes encapsulated in degradable hydrogels. Biomedical Materials 2012, 7(2):024111.
46. Soltz M.A., Ateshian G.A. Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. Journal of Biomechanics 1998, 31(10):927-934.
47. Strange D.G., Oyen M.L. Composite hydrogels for nucleus pulposus tissue engineering. Journal of the Mechanical Behavior of Biomedical Materials 2012, 11:16-26.
48. Urban J.P.G., Roberts S., Ralphs J.R. The nucleus of the intervertebral disc from development to degeneration. American Zoologist 2000, 40(1):53-61.
49. van Blitterswijk W.J., van de Nes J.C., et al. Glucosamine and chondroitin sulfate supplementation to treat symptomatic disc degeneration: biochemical rationale and case report. BMC Complementary and Alternative Medicine 2003, 3:2.
50. Wan L.Q., Jiang J., et al. Calcium concentration effects on the mechanical and biochemical properties of chondrocyte-alginate constructs. Cellular and Molecular Bioengineering 2008, 1(1):93-102.
51. Wong M., Siegrist M., et al. Collagen fibrillogenesis by chondrocytes in alginate. Tissue Engineering 2002, 8(6):979-987.
52. Yue J., Morgenstern R., Morgenstern C., Lauryssen C Shape memory hydrogels-A novel material for treating age-related degenerative conditions of the spine. European Musculoskeletal Review 2011, 6(3):184-188.
53. Zhang H., Wang L., et al. Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury. Arthritis Research and Therapy 2009, 11(6):R172.