Composite hydrogels for nucleus pulposus tissue engineering

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 11, Issue , 2012, Pages 16-26

  Strange, Daniel G T ^a   Oyen, Michelle L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Hydrogels; Indentation; Mechanical characterisation; Poroelasticity; Viscoelasticity

Indexed keywords

AMORPHOUS GELS; BACK PAIN; BIOMECHANICAL PROPERTIES; COMPOSITE GELS; COMPOSITE HYDROGELS; COMPRESSIVE LOADS; CURRENT TREATMENTS; ELASTIC BEHAVIOUR; HYDROGEL SCAFFOLDS; INTERVERTEBRAL DISCS; MECHANICAL BEHAVIOUR; MECHANICAL CHARACTERISATION; NUCLEUS PULPOSUS; NUTRIENT TRANSPORT; PARADIGM SHIFTS; PORO-ELASTICITY; POROELASTIC; POROELASTIC BEHAVIOUR; TIME-DEPENDENT; TIME-DEPENDENT PROPERTIES; TIME-DEPENDENT RESPONSE; TISSUE ENGINEERING APPLICATIONS; UNCONFINED COMPRESSION;

ALGAE; BIOMECHANICS; INDENTATION; MECHANICAL PROPERTIES; POLYSACCHARIDES; TISSUE; TISSUE ENGINEERING; VISCOELASTICITY;

HYDROGELS;

AGAR; GELATIN;

ARTICLE; BACKACHE; COMPOSITE MATERIAL; COMPRESSION; HYDROGEL; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LOADING TEST; MACHINE; MATERIALS TESTING; MECHANICAL STRESS; NUCLEUS PULPOSUS; POROELASTICITY; PRIORITY JOURNAL; SPINE DISEASE; TISSUE ENGINEERING; VISCOELASTICITY;

AGAR; COMPRESSIVE STRENGTH; ELASTICITY; GELATIN; HYDROGELS; INTERVERTEBRAL DISC; MATERIALS TESTING; MECHANICAL PROCESSES; TIME FACTORS; TISSUE ENGINEERING; VISCOSITY;

EID: 84861671921     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2011.10.003     Document Type: Article

References (33)

1. Andersson G.B. Epidemiological features of chronic low-back pain. Lancet 1999, 354(9178):581-585.
2. Baer A.E., Wang J.Y., Kraus V.B., Setton L.A. Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. Journal of Orthopaedic Research 2001, 19(1):2-10.
3. Clark A.H., Richardson R.K., Ross-Murphy S.B., Stubbs J.M. Structural and mechanical properties of agar/gelatin co-gels. Small-deformation studies. Macromolecules 1983, 16(8):1367-1374.
4. Cloyd J.M., Malhotra N.R., Weng L., Chen W., Mauck R.L., Elliott D.M. Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds. European Spine Journal 2007, 16(11):1892-1898.
5. Dong Z., Wang Q., Du Y. Alginate/gelatin blend films and their properties for drug controlled release. Journal of Membrane Science 2006, 280(1-2):37-44.
6. Drury J.L., Mooney D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 2003, 24:4337-4351.
7. Galli M., Comley K.S., Shean T.A., Oyen M.L. Viscoelastic and poroelastic mechanical characterization of hydrated gels. Journal of Materials Research 2009, 24(3):973-979.
8. Galli M., Fornasiere E., Cugnoni J., Oyen M.L. Poroviscoelastic characterization of particle-reinforced gelatin gels using indentation and homogenization. Journal of the Mechanical Behavior of Biomedical Materials 2011, 4(4):610-617.
9. Galli M., Oyen M.L. Fast identification of poroelastic parameters from indentation tests. Computer Modeling in Engineering & Sciences 2009, 48(3):241-268.
10. Gotlieb A., Plashchina I., Braudo E., Titova E., Belavtseva E., Tolstoguzov V. Investigation of mixed agarose-gelatin gels. Nahrung/Food 1988, 32(10):927-937.
11. Gruber H.E., Hoelscher G.L., Leslie K., Ingram J.A., Hanley E.N. Three-dimensional culture of human disc cells within agarose or a collagen sponge: assessment of proteoglycan production. Biomaterials 2006, 27(3):371-376.
12. Heneghan P., Riches P.E. Determination of the strain-dependent hydraulic permeability of the compressed bovine nucleus pulposus. Journal of Biomechanics 2008, 41(4):903-906.
13. Hu Y., Zhao X., Vlassak J.J., Suo Z. Using indentation to characterize the poroelasticity of gels. Applied Physics Letters 2010, 96(12):121904.
14. Iatridis J.C., Weidenbaum M., Setton L., Mow V. Is the nucleus pulposus a solid or a fluid? mechanical behaviors of the nucleus pulposus of the human intervertebral disc. Spine 1996, 21(10):1174-1184.
15. Johannessen W., Elliott D.M. Effects of degeneration on the biphasic material properties of human nucleus pulposus in confined compression. Spine 2005, 30(24):E724-E729.
16. Johnson E.M., Deen W.M. Hydraulic permeability of agarose gels. AIChE Journal 1996, 42(5):1220-1224.
17. Johnson K.L. Contact Mechanics 1985, Cambridge University Press, Cambridge, UK.
18. Joshi A., Massey C.J., Karduna A., Vresilovic E., Marcolongo M. The effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: a finite element study. Journal of Biomedical Materials Research. Part B, Applied Biomaterials 2009, 90(2):596-607.
19. Lee E.H., Radok J.R.M. Contact problem for viscoelastic bodies. Journal of Applied Mechanics 1960, 27:438-444.
20. Mattice J., Lau A., Oyen M., Kent R. Spherical indentation load-relaxation of soft biological tissues. Journal of Materials Research 2006, 21(8):2003-2010.
21. Nerurkar N.L., Elliott D.M., Mauck R.L. Mechanical design criteria for intervertebral disc tissue engineering. Journal of Biomechanics 2010, 43(6):1017-1030.
22. Oyen M.L. Spherical indentation creep following ramp loading. Journal of Materials Research 2005, 20(8):2094-2100.
23. Oyen M.L. Analytical techniques for indentation of viscoelastic materials. Philosophical Magazine 2006, 86(33-35):5625-5641.
24. Oyen M.L., Ferguson V.L., Bembey A.K., Bushby A.J., Boyde A. Composite bounds on the elastic modulus of bone. Journal of Biomechanics 2008, 41(11):2585-2588.
25. Périé D., Korda D., Iatridis J.C. Confined compression experiments on bovine nucleus pulposus and annulus fibrosus: sensitivity of the experiment in the determination of compressive modulus and hydraulic permeability. Journal of Biomechanics 2005, 38(11):2164-2171.
26. Qiang B., Greenleaf J., Oyen M.L., Zhang X. Estimation of material elasticity by spherical indentation load-relaxation tests on viscoelastic samples of finite thickness. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 2011, 57:1418-1429.
27. Séguin C.A., Grynpas M.D., Pilliar R.M., Waldman S.D., Kandel R.A. Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate. Spine 2004, 29(12):1299-1306. discussion 1306-7.
28. Strange D.G.T., Fisher S.T., Boughton P.C., Kishen T.J., Diwan A.D. Restoration of compressive loading properties of lumbar discs with a nucleus implant-a finite element analysis study. The Spine Journal 2010, 10(7):602-609.
29. Tibbitt M.W., Anseth K.S. Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnology and bioengineering 2009, 103(4):655-663.
30. Urban J., Maroudas A. Swelling of the intervertebral disc in vitro. Connective Tissue Research 1981, 9(1):1-10.
31. Wang H.F. Theory of Linear Poroelasticity with Applications to Geomechanics and Hydrogeology 2000, Princeton University Press, Princeton, NJ.
32. Watase M., Nishinari K. Rheological properties of agarose-gelatin gels. Rheologica Acta 1980, 19(2):220-225.
33. Wilke H.J., Neef P., Caimi M., Hoogland T., Claes L.E. New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 1999, 24(8):755-762.