Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model

Journal of Inherited Metabolic Disease

Volumn 36, Issue 5, 2013, Pages 721-730

  Scaini, Giselli ^a,b   Comim, Clarissa M ^a,b   Oliveira, Giovanna M T ^b,c   Pasquali, Matheus A B ^d   Quevedo, João ^a,b   Gelain, Daniel P ^d   Moreira, José Cláudio F ^d   Schuck, Patrícia F ^a   Ferreira, Gustavo C ^a   Bogo, Maurício R ^b,c   Streck, Emilio L ^a,b  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b Instituto Nacional de Ciencia e Tecnologia Translacional em Medicina INCT TM   (Brazil)

^c PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ANTIOXIDANT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN PROTEIN; BRANCHED CHAIN AMINO ACID; DEFEROXAMINE; ISOLEUCINE; LEUCINE; MESSENGER RNA; VALINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; MALE; MAPLE SYRUP URINE DISEASE; MEMORY DISORDER; NONHUMAN; OPEN FIELD TEST; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN LOCALIZATION; RAT; SPATIAL MEMORY; TISSUE DISTRIBUTION;

ACETYLCYSTEINE; AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; ANTIOXIDANTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; DEFEROXAMINE; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MALE; MAPLE SYRUP URINE DISEASE; MEMORY; MEMORY DISORDERS; OXIDATIVE STRESS; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 84884356435     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-012-9549-z     Document Type: Article

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