-
1
-
-
34250163547
-
Spatiotemporal micropatterning of cells on arbitrary substrates
-
10.1021/ac062371p
-
V.V. Abhyankar, D.J. Beebe, Spatiotemporal micropatterning of cells on arbitrary substrates. Anal. Chem. 79(11), 4066-4073 (2007)
-
(2007)
Anal. Chem.
, vol.79
, Issue.11
, pp. 4066-4073
-
-
Abhyankar, V.V.1
Beebe, D.J.2
-
2
-
-
52649140667
-
A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment
-
10.1039/b803533d
-
V.V. Abhyankar, M.W. Toepke, C.L. Cortesio et al., A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment. Lab Chip 8(9), 1507-1515 (2008)
-
(2008)
Lab Chip
, vol.8
, Issue.9
, pp. 1507-1515
-
-
Abhyankar, V.V.1
Toepke, M.W.2
Cortesio, C.L.3
-
3
-
-
0037420747
-
Formation of steady-state oxygen gradients in vitro: Application to liver zonation
-
10.1002/bit.10569
-
J.W. Allen, S.N. Bhatia, Formation of steady-state oxygen gradients in vitro: application to liver zonation. Biotechnol. Bioeng. 82(3), 253-262 (2003)
-
(2003)
Biotechnol. Bioeng.
, vol.82
, Issue.3
, pp. 253-262
-
-
Allen, J.W.1
Bhatia, S.N.2
-
4
-
-
14844320510
-
In vitro zonation and toxicity in a hepatocyte bioreactor
-
10.1093/toxsci/kfi052
-
J.W. Allen, S.R. Khetani, S.N. Bhatia, In vitro zonation and toxicity in a hepatocyte bioreactor. Toxicol. Sci. 84(1), 110-119 (2005)
-
(2005)
Toxicol. Sci.
, vol.84
, Issue.1
, pp. 110-119
-
-
Allen, J.W.1
Khetani, S.R.2
Bhatia, S.N.3
-
5
-
-
69549115993
-
The microfluidic palette: A diffusive gradient generator with spatio-temporal control
-
10.1039/b902113b
-
J. Atencia, J. Morrow, L.E. Locascio, The microfluidic palette: a diffusive gradient generator with spatio-temporal control. Lab Chip 9(18), 2707-2714 (2009)
-
(2009)
Lab Chip
, vol.9
, Issue.18
, pp. 2707-2714
-
-
Atencia, J.1
Morrow, J.2
Locascio, L.E.3
-
6
-
-
84055207544
-
A robust diffusion-based gradient generator for dynamic cell assays
-
10.1039/c1lc20829b
-
J. Atencia, G.A. Cooksey, L.E. Locascio, A robust diffusion-based gradient generator for dynamic cell assays. Lab Chip 12(2), 309-316 (2012)
-
(2012)
Lab Chip
, vol.12
, Issue.2
, pp. 309-316
-
-
Atencia, J.1
Cooksey, G.A.2
Locascio, L.E.3
-
7
-
-
0032721936
-
Effect of cell-cell interactions in preservation of cellular phenotype: Cocultivation of hepatocytes and nonparenchymal cells
-
S.N. Bhatia, U.J. Balis, M.L. Yarmush et al., Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells. FASEB J. 13(14), 1883-1900 (1999)
-
(1999)
FASEB J.
, vol.13
, Issue.14
, pp. 1883-1900
-
-
Bhatia, S.N.1
Balis, U.J.2
Yarmush, M.L.3
-
8
-
-
39149134920
-
Effects of hepatic zonal oxygen levels on hepatocyte stress responses
-
10.1016/j.jss.2007.04.014
-
T.A. Broughan, R. Naukam, C. Tan et al., Effects of hepatic zonal oxygen levels on hepatocyte stress responses. J. Surg. Res. 145(1), 150-160 (2008)
-
(2008)
J. Surg. Res.
, vol.145
, Issue.1
, pp. 150-160
-
-
Broughan, T.A.1
Naukam, R.2
Tan, C.3
-
9
-
-
33846932052
-
Generation of complex concentration profiles in microchannels in a logarithmically small number of steps
-
10.1039/b610011b
-
K. Campbell, A. Groisman, Generation of complex concentration profiles in microchannels in a logarithmically small number of steps. Lab Chip 7(2), 264-272 (2007)
-
(2007)
Lab Chip
, vol.7
, Issue.2
, pp. 264-272
-
-
Campbell, K.1
Groisman, A.2
-
10
-
-
52449122645
-
In vitro analysis of a hepatic device with intrinsic microvascular-based channels
-
10.1007/s10544-008-9194-3
-
A. Carraro, W.M. Hsu, K.M. Kulig et al., In vitro analysis of a hepatic device with intrinsic microvascular-based channels. Biomed. Microdevices 10(6), 795-805 (2008)
-
(2008)
Biomed. Microdevices
, vol.10
, Issue.6
, pp. 795-805
-
-
Carraro, A.1
Hsu, W.M.2
Kulig, K.M.3
-
11
-
-
80054021855
-
Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions
-
10.1039/c1lc20325h
-
Y.A. Chen, A.D. King, H.C. Shih et al., Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions. Lab Chip. 11(21), 3626-33 (2011)
-
(2011)
Lab Chip.
, vol.11
, Issue.21
, pp. 3626-3633
-
-
Chen, Y.A.1
King, A.D.2
Shih, H.C.3
-
12
-
-
77956944070
-
Microfluidic gradient platforms for controlling cellular behavior
-
10.1002/elps.201000137
-
B.G. Chung, J. Choo, Microfluidic gradient platforms for controlling cellular behavior. Electrophoresis. 31(18), 3014-27 (2010)
-
(2010)
Electrophoresis.
, vol.31
, Issue.18
, pp. 3014-3027
-
-
Chung, B.G.1
Choo, J.2
-
13
-
-
17144398875
-
Human neural stem cell growth and differentiation in a gradient-generating microfluidic device
-
10.1039/b417651k
-
B.G. Chung, L.A. Flanagan, S.W. Rhee et al., Human neural stem cell growth and differentiation in a gradient-generating microfluidic device. Lab Chip 5(4), 401-406 (2005)
-
(2005)
Lab Chip
, vol.5
, Issue.4
, pp. 401-406
-
-
Chung, B.G.1
Flanagan, L.A.2
Rhee, S.W.3
-
14
-
-
37349009261
-
Micro- and nanoscale technologies for tissue engineering and drug discovery applications
-
10.1517/17460441.2.12.1653
-
B.G. Chung, L.F. Kang, A. Khademhosseini, Micro- and nanoscale technologies for tissue engineering and drug discovery applications. Expert Opin. Drug Discov. 2(12), 1653-1668 (2007)
-
(2007)
Expert Opin. Drug Discov.
, vol.2
, Issue.12
, pp. 1653-1668
-
-
Chung, B.G.1
Kang, L.F.2
Khademhosseini, A.3
-
15
-
-
70349399012
-
Liver tissue engineering in the evaluation of drug safety
-
10.1517/17425250903160664
-
A. Dash, W. Inman, K. Hoffmaster et al., Liver tissue engineering in the evaluation of drug safety. Expert Opin. Drug Metab. Toxicol. 5(10), 1159-1174 (2009)
-
(2009)
Expert Opin. Drug Metab. Toxicol.
, vol.5
, Issue.10
, pp. 1159-1174
-
-
Dash, A.1
Inman, W.2
Hoffmaster, K.3
-
16
-
-
78650062139
-
A review of three-dimensional in vitro tissue models for drug discovery and transport studies
-
10.1002/jps.22257
-
N.T. Elliott, F. Yuan, A review of three-dimensional in vitro tissue models for drug discovery and transport studies. J. Pharm. Sci. 100(1), 59-74 (2011)
-
(2011)
J. Pharm. Sci.
, vol.100
, Issue.1
, pp. 59-74
-
-
Elliott, N.T.1
Yuan, F.2
-
17
-
-
84862146642
-
Microfluidic Platforms for Hepatocyte Cell Culture: New Technologies and Applications
-
V.N. Goral, and P.K. Yuen, "Microfluidic Platforms for Hepatocyte Cell Culture: New Technologies and Applications," Ann. Biomed. Eng (2012)
-
(2012)
Ann. Biomed. Eng
-
-
Goral, V.N.1
Yuen, P.K.2
-
18
-
-
18244366662
-
Tissue engineering-current challenges and expanding opportunities
-
10.1126/science.1069210
-
L.G. Griffith, G. Naughton, Tissue engineering-current challenges and expanding opportunities. Science 295(5557), 1009-1014 (2002)
-
(2002)
Science
, vol.295
, Issue.5557
, pp. 1009-1014
-
-
Griffith, L.G.1
Naughton, G.2
-
19
-
-
33644529130
-
Capturing complex 3D tissue physiology in vitro
-
10.1038/nrm1858
-
L.G. Griffith, M.A. Swartz, Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7(3), 211-224 (2006)
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, Issue.3
, pp. 211-224
-
-
Griffith, L.G.1
Swartz, M.A.2
-
20
-
-
33645383666
-
Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients
-
10.1039/b511877h
-
D. Irimia, S.Y. Liu, W.G. Tharp et al., Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip 6(2), 191-198 (2006)
-
(2006)
Lab Chip
, vol.6
, Issue.2
, pp. 191-198
-
-
Irimia, D.1
Liu, S.Y.2
Tharp, W.G.3
-
21
-
-
77957859805
-
Induced charge electro-osmotic concentration gradient generator
-
10.1063/1.3368991
-
M. Jain, A. Yeung, K. Nandakumar, Induced charge electro-osmotic concentration gradient generator. Biomicrofluidics. 4(1), 14110 (2010)
-
(2010)
Biomicrofluidics.
, vol.4
, Issue.1
, pp. 14110
-
-
Jain, M.1
Yeung, A.2
Nandakumar, K.3
-
22
-
-
0024336445
-
Functional specialization of different hepatocyte populations
-
K. Jungermann, N. Katz, Functional specialization of different hepatocyte populations. Physiol. Rev. 69(3), 708-764 (1989)
-
(1989)
Physiol. Rev.
, vol.69
, Issue.3
, pp. 708-764
-
-
Jungermann, K.1
Katz, N.2
-
23
-
-
0033960898
-
Oxygen: Modulator of metabolic zonation and disease of the liver
-
10.1002/hep.510310201
-
K. Jungermann, T. Kietzmann, Oxygen: modulator of metabolic zonation and disease of the liver. Hepatology 31(2), 255-260 (2000)
-
(2000)
Hepatology
, vol.31
, Issue.2
, pp. 255-260
-
-
Jungermann, K.1
Kietzmann, T.2
-
24
-
-
37349027919
-
Biomolecular gradients in cell culture systems
-
10.1039/b711887b
-
T.M. Keenan, A. Folch, Biomolecular gradients in cell culture systems. Lab Chip 8(1), 34-57 (2008)
-
(2008)
Lab Chip
, vol.8
, Issue.1
, pp. 34-57
-
-
Keenan, T.M.1
Folch, A.2
-
25
-
-
77951912747
-
A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber
-
10.1039/b913494h
-
T.M. Keenan, C.W. Frevert, A. Wu et al., A new method for studying gradient-induced neutrophil desensitization based on an open microfluidic chamber. Lab Chip. 10(1), 116-22 (2010)
-
(2010)
Lab Chip.
, vol.10
, Issue.1
, pp. 116-122
-
-
Keenan, T.M.1
Frevert, C.W.2
Wu, A.3
-
26
-
-
33846032329
-
A microfluidic platform for 3-dimensional cell culture and cell-based assays
-
10.1007/s10544-006-9016-4
-
M.S. Kim, J.H. Yeon, J.K. Park, A microfluidic platform for 3-dimensional cell culture and cell-based assays. Biomed. Microdevices 9(1), 25-34 (2007)
-
(2007)
Biomed. Microdevices
, vol.9
, Issue.1
, pp. 25-34
-
-
Kim, M.S.1
Yeon, J.H.2
Park, J.K.3
-
27
-
-
40349088589
-
In situ micropatterning technique by cell crushing for co-cultures inside microfluidic biochips
-
10.1007/s10544-007-9122-y
-
E. Leclerc, K. El Kirat, L. Griscom, In situ micropatterning technique by cell crushing for co-cultures inside microfluidic biochips. Biomed. Microdevices 10(2), 169-177 (2008)
-
(2008)
Biomed. Microdevices
, vol.10
, Issue.2
, pp. 169-177
-
-
Leclerc, E.1
El Kirat, K.2
Griscom, L.3
-
29
-
-
84862181007
-
Organotypic liver culture models: Meeting current challenges in toxicity testing
-
10.3109/10408444.2012.682115
-
E.L. LeCluyse, R.P. Witek, M.E. Andersen et al., Organotypic liver culture models: meeting current challenges in toxicity testing. Crit. Rev. Toxicol. 42(6), 501-48 (2012)
-
(2012)
Crit. Rev. Toxicol.
, vol.42
, Issue.6
, pp. 501-548
-
-
Lecluyse, E.L.1
Witek, R.P.2
Andersen, M.E.3
-
30
-
-
34547581758
-
An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture
-
10.1002/bit.21360
-
P.J. Lee, P.J. Hung, L.P. Lee, An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture. Biotechnol. Bioeng. 97(5), 1340-1346 (2007)
-
(2007)
Biotechnol. Bioeng.
, vol.97
, Issue.5
, pp. 1340-1346
-
-
Lee, P.J.1
Hung, P.J.2
Lee, L.P.3
-
31
-
-
18244384464
-
Neutrophil migration in opposing chemoattractant gradients using microfluidic chemotaxis devices
-
10.1007/s10439-005-2503-6
-
F. Lin, C.M. Nguyen, S.J. Wang et al., Neutrophil migration in opposing chemoattractant gradients using microfluidic chemotaxis devices. Ann. Biomed. Eng. 33(4), 475-482 (2005)
-
(2005)
Ann. Biomed. Eng.
, vol.33
, Issue.4
, pp. 475-482
-
-
Lin, F.1
Nguyen, C.M.2
Wang, S.J.3
-
32
-
-
0031012845
-
Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver
-
10.1016/S0306-3623(96)00183-8
-
K.O. Lindros, Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver. Gen. Pharmacol. 28(2), 191-196 (1997)
-
(1997)
Gen. Pharmacol.
, vol.28
, Issue.2
, pp. 191-196
-
-
Lindros, K.O.1
-
33
-
-
34249794264
-
A cell-laden microfluidic hydrogel
-
10.1039/b615486g
-
Y. Ling, J. Rubin, Y. Deng et al., A cell-laden microfluidic hydrogel. Lab Chip 7(6), 756-762 (2007)
-
(2007)
Lab Chip
, vol.7
, Issue.6
, pp. 756-762
-
-
Ling, Y.1
Rubin, J.2
Deng, Y.3
-
34
-
-
33750132217
-
A Novel Micro-Tissue Reactor for Maintaining Hepatocytes in Vitro
-
M-C.S. Y.-S. W. T.-C. S. R.-J. G. C.-H. Liu
-
M-C. S. Y.-S. W. T.-C. S. R.-J. G. C.-H. Liu, "A Novel Micro-Tissue Reactor for Maintaining Hepatocytes in Vitro," MEMS 2006 Conference, pp. 458-461 (2006)
-
(2006)
MEMS 2006 Conference
, pp. 458-461
-
-
-
35
-
-
33644810257
-
Sinusoidal endothelial cells as an early target for hepatic toxicants
-
R.S. McCuskey, Sinusoidal endothelial cells as an early target for hepatic toxicants. Clin. Hemorheol. Microcirc. 34(1-2), 5-10 (2006)
-
(2006)
Clin. Hemorheol. Microcirc.
, vol.34
, Issue.1-2
, pp. 5-10
-
-
McCuskey, R.S.1
-
36
-
-
77951092829
-
Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels
-
10.1016/j.biomaterials.2010.01.138
-
G. Mehta, C.M. Williams, L. Alvarez et al., Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels. Biomaterials. 31(17), 4657-71 (2010)
-
(2010)
Biomaterials.
, vol.31
, Issue.17
, pp. 4657-4671
-
-
Mehta, G.1
Williams, C.M.2
Alvarez, L.3
-
37
-
-
77953110115
-
Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices
-
10.1039/c001552k
-
L.J. Millet, M.E. Stewart, R.G. Nuzzo et al., Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices. Lab Chip 10(12), 1525-35 (2010)
-
(2010)
Lab Chip
, vol.10
, Issue.12
, pp. 1525-1535
-
-
Millet, L.J.1
Stewart, M.E.2
Nuzzo, R.G.3
-
38
-
-
79959866368
-
Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device
-
10.1063/1.3580753
-
Y. Nakao, H. Kimura, Y. Sakai et al., Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device. Biomicrofluidics. 5(2), 22212 (2011)
-
(2011)
Biomicrofluidics.
, vol.5
, Issue.2
, pp. 22212
-
-
Nakao, Y.1
Kimura, H.2
Sakai, Y.3
-
39
-
-
19544374885
-
Microfabricated grooved substrates as platforms for bioartificial liver reactors
-
10.1002/bit.20463
-
J. Park, F. Berthiaume, M. Toner et al., Microfabricated grooved substrates as platforms for bioartificial liver reactors. Biotechnol. Bioeng. 90(5), 632-644 (2005)
-
(2005)
Biotechnol. Bioeng.
, vol.90
, Issue.5
, pp. 632-644
-
-
Park, J.1
Berthiaume, F.2
Toner, M.3
-
40
-
-
36349021851
-
Gradient generation by an osmotic pump and the behavior of human mesenchymal stem cells under the fetal bovine serum concentration gradient
-
10.1039/b710777c
-
J.Y. Park, C.M. Hwang, S.H. Lee, Gradient generation by an osmotic pump and the behavior of human mesenchymal stem cells under the fetal bovine serum concentration gradient. Lab Chip 7(12), 1673-1680 (2007)
-
(2007)
Lab Chip
, vol.7
, Issue.12
, pp. 1673-1680
-
-
Park, J.Y.1
Hwang, C.M.2
Lee, S.H.3
-
41
-
-
72849143548
-
Differentiation of neural progenitor cells in a microfluidic chip-generated cytokine gradient
-
10.1002/stem.202
-
J.Y. Park, S.K. Kim, D.H. Woo et al., Differentiation of neural progenitor cells in a microfluidic chip-generated cytokine gradient. Stem Cells 27(11), 2646-2654 (2009)
-
(2009)
Stem Cells
, vol.27
, Issue.11
, pp. 2646-2654
-
-
Park, J.Y.1
Kim, S.K.2
Woo, D.H.3
-
42
-
-
55049100842
-
Inhibition and induction of human cytochrome P450 enzymes: Current status
-
10.1007/s00204-008-0332-8
-
O. Pelkonen, M. Turpeinen, J. Hakkola et al., Inhibition and induction of human cytochrome P450 enzymes: current status. Arch. Toxicol. 82(10), 667-715 (2008)
-
(2008)
Arch. Toxicol.
, vol.82
, Issue.10
, pp. 667-715
-
-
Pelkonen, O.1
Turpeinen, M.2
Hakkola, J.3
-
43
-
-
18744407435
-
Microfluidic gradient-generating device for pharmacological profiling
-
10.1021/ac050218+
-
J. Pihl, J. Sinclair, E. Sahlin et al., Microfluidic gradient-generating device for pharmacological profiling. Anal. Chem. 77(13), 3897-3903 (2005)
-
(2005)
Anal. Chem.
, vol.77
, Issue.13
, pp. 3897-3903
-
-
Pihl, J.1
Sinclair, J.2
Sahlin, E.3
-
44
-
-
0034711410
-
From micro- to nanofabrication with soft materials
-
10.1126/science.290.5496.1536
-
S.R. Quake, A. Scherer, From micro- to nanofabrication with soft materials. Science 290(5496), 1536-1540 (2000)
-
(2000)
Science
, vol.290
, Issue.5496
, pp. 1536-1540
-
-
Quake, S.R.1
Scherer, A.2
-
45
-
-
33846036487
-
Evaluation of effects of shear stress on hepatocytes by a microchip-based system
-
10.1088/0957-0233/17/12/S08
-
Y. Tanaka, M. Yamato, T. Okano et al., Evaluation of effects of shear stress on hepatocytes by a microchip-based system. Meas. Sci. Technol. 17(12), 3167-3170 (2006)
-
(2006)
Meas. Sci. Technol.
, vol.17
, Issue.12
, pp. 3167-3170
-
-
Tanaka, Y.1
Yamato, M.2
Okano, T.3
-
46
-
-
67650481611
-
A microfluidic 3D hepatocyte chip for drug toxicity testing
-
10.1039/b900912d
-
Y.C. Toh, T.C. Lim, D. Tai et al., A microfluidic 3D hepatocyte chip for drug toxicity testing. Lab Chip 9(14), 2026-2035 (2009)
-
(2009)
Lab Chip
, vol.9
, Issue.14
, pp. 2026-2035
-
-
Toh, Y.C.1
Lim, T.C.2
Tai, D.3
-
47
-
-
77955530388
-
Advancing stem cell research with microtechnologies: Opportunities and challenges
-
10.1039/c0ib00004c
-
Y.C. Toh, K. Blagovic, J. Voldman, Advancing stem cell research with microtechnologies: opportunities and challenges. Integr. Biol. (Camb). 2(7-8), 305-25 (2010)
-
(2010)
Integr. Biol. (Camb).
, vol.2
, Issue.7-8
, pp. 305-325
-
-
Toh, Y.C.1
Blagovic, K.2
Voldman, J.3
-
48
-
-
0034615958
-
Monolithic microfabricated valves and pumps by multilayer soft lithography
-
10.1126/science.288.5463.113
-
M.A. Unger, H.P. Chou, T. Thorsen et al., Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288(5463), 113-116 (2000)
-
(2000)
Science
, vol.288
, Issue.5463
, pp. 113-116
-
-
Unger, M.A.1
Chou, H.P.2
Thorsen, T.3
-
49
-
-
79959549073
-
Microfluidic devices for in vitro studies on liver drug metabolism and toxicity
-
10.1039/c0ib00119h
-
P.M. van Midwoud, E. Verpoorte, G.M. Groothuis, Microfluidic devices for in vitro studies on liver drug metabolism and toxicity. Integr. Biol. (Camb). 3(5), 509-21 (2011)
-
(2011)
Integr. Biol. (Camb).
, vol.3
, Issue.5
, pp. 509-521
-
-
Van Midwoud, P.M.1
Verpoorte, E.2
Groothuis, G.M.3
-
50
-
-
36349024270
-
Cell-based high content screening using an integrated microfluidic device
-
10.1039/b711513j
-
N. Ye, J. Qin, W. Shi et al., Cell-based high content screening using an integrated microfluidic device. Lab Chip 7(12), 1696-1704 (2007)
-
(2007)
Lab Chip
, vol.7
, Issue.12
, pp. 1696-1704
-
-
Ye, N.1
Qin, J.2
Shi, W.3
|