Formation of steady-state oxygen gradients in vitro: Application to liver zonation

Biotechnology and Bioengineering

Volumn 82, Issue 3, 2003, Pages 253-262

  Allen, Jared W ^a   Bhatia, Sangeeta N ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Bioreactor; Hepatocyte; Oxygen gradient; Zonation

Indexed keywords

ARTIFICIAL ORGANS; BIOREACTORS; CELLS; DETOXIFICATION; ENZYMES; TOXICITY;

PERFUSION BIOREACTOR SYSTEM;

BIOMEDICAL ENGINEERING;

CYTOCHROME P450 2B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOXIA; ARTICLE; BACTERIUM CULTURE; BIOARTIFICIAL ORGAN; BIOREACTOR; CELL COMPARTMENTALIZATION; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; IN VITRO STUDY; LIPID PEROXIDATION; LIVER CELL; NONHUMAN; OXYGEN TRANSPORT; RAT; REPERFUSION INJURY; STEADY STATE; ZONATION;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; COMPUTER SIMULATION; CYTOCHROME P-450 ENZYME SYSTEM; EQUIPMENT DESIGN; FEMALE; HEPATOCYTES; MODELS, BIOLOGICAL; OXYGEN; OXYGEN CONSUMPTION; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); RATS; RATS, INBRED LEW; RHEOLOGY;

EID: 0037420747     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10569     Document Type: Article

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