The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells

Journal of Experimental Medicine

Volumn 210, Issue 8, 2013, Pages 1501-1507

  Rouaud, Pauline ^a   Vincent Fabert, Christelle ^a,c   Saintamand, Alexis ^a   Fiancette, Rémi ^a,d   Marquet, Marie ^a   Robert, Isabelle ^b   Reina San Martin, Bernardo ^b   Pinaud, Eric ^a   Cogné, Michel ^a   Denizot, Yves ^a  

^a UNIVERSITY OF LIMOGES   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; IMMUNOGLOBULIN HEAVY CHAIN;

ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; CONTROLLED STUDY; EXON; GERMINAL CENTER; HEAVY CHAIN; IMMUNOGLOBULIN VARIABLE REGION; LIGHT CHAIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; SOMATIC HYPERMUTATION; VDJ RECOMBINATION;

3' UNTRANSLATED REGIONS; ANIMALS; B-LYMPHOCYTES; CHROMATIN IMMUNOPRECIPITATION; CYTIDINE DEAMINASE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GERMINAL CENTER; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, KNOCKOUT; REGULATORY SEQUENCES, NUCLEIC ACID; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSCRIPTION, GENETIC; VDJ EXONS;

EID: 84884278329     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130072     Document Type: Article

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