Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region

Journal of Experimental Medicine

Volumn 206, Issue 12, 2009, Pages 2613-2623

  Dunnick, Wesley A ^a   Collins, John T ^a   Shi, Jian ^a   Westfield, Gerwin ^a   Fontaine, Clinton ^a   Hakimpour, Paul ^b   Papavasiliou, F Nina ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN BINDING FACTOR BAC; UNCLASSIFIED DRUG; CYTIDINE DEAMINASE; IMMUNOGLOBULIN HEAVY CHAIN; INTEGRASE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CHROMOSOME; CLASS SWITCH RECOMBINATION; CONTROLLED STUDY; DNA RECOMBINATION; FEMALE; GENE DELETION; GENE INSERTION; GENE LOCUS; GENE SWITCHING; GENETIC VARIABILITY; HEAVY CHAIN; LOXP SITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC HYPERMUTATION; TRANSGENE; VDJ EXON; ANIMAL; CHICKEN; ENHANCER REGION; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; TRANSGENIC MOUSE;

3' UNTRANSLATED REGIONS; ANIMALS; B-LYMPHOCYTES; CHICKENS; CYTIDINE DEAMINASE; ENHANCER ELEMENTS, GENETIC; IMMUNOGLOBULIN HEAVY CHAINS; INTEGRASES; MICE; MICE, TRANSGENIC; QUANTITATIVE TRAIT LOCI; RECOMBINATION, GENETIC; SEQUENCE DELETION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSCRIPTION, GENETIC; TRANSGENES; VDJ EXONS;

EID: 73349098453     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091280     Document Type: Article

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