Chemical library screening using a SPR-based inhibition in solution assay: Simulations and experimental validation

Analytical Chemistry

Volumn 85, Issue 18, 2013, Pages 8787-8795

  Choulier, Laurence ^a   Nominé, Yves ^a   Zeder Lutz, Gabrielle ^a   Charbonnier, Sebastian ^a   Didier, Bruno ^b   Jung, Marie Louise ^b   Altschuh, Danièle ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Prestwick Chemical   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL LIBRARIES; CONCENTRATION-DEPENDENT; EXPERIMENTAL VALIDATIONS; MOBILE PHASE; PDZ DOMAINS; POTENTIAL INHIBITORS; PROTEIN-PROTEIN INTERACTIONS; SURFACE BOUNDS;

BINDERS; PEPTIDES;

SURFACE PLASMON RESONANCE;

MAGI1 PROTEIN, HUMAN; NERVE CELL ADHESION MOLECULE;

AMINO ACID SEQUENCE; ARTICLE; COMPUTER SIMULATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOLECULAR LIBRARY; PHYSIOLOGY; PROTEIN BINDING; RANDOMIZATION; SOLUTION AND SOLUBILITY; SURFACE PLASMON RESONANCE; VALIDATION STUDY;

AMINO ACID SEQUENCE; CELL ADHESION MOLECULES, NEURONAL; COMPUTER SIMULATION; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RANDOM ALLOCATION; SMALL MOLECULE LIBRARIES; SOLUTIONS; SURFACE PLASMON RESONANCE;

EID: 84884277435     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac4019445     Document Type: Article

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