Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists

European Journal of Medicinal Chemistry

Volumn 65, Issue , 2013, Pages 41-50

  Lambertucci, Catia ^a   Sundukova, Mayya ^b   Kachare, Dhuldeo D ^a   Panmand, Deepak S ^a   Dal Ben, Diego ^a   Buccioni, Michela ^a   Marucci, Gabriella ^a   Marchenkova, Anna ^b   Thomas, Ajiroghene ^a   Nistri, Andrea ^b   Cristalli, Gloria ^a   Volpini, Rosaria ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b SISSA   (Italy)

Author keywords

Adenine derivatives; ATP; P2X3 receptor; P2X3 receptor antagonists; Patch clamp; Purine; Purine derivatives; Purinergic receptors

Indexed keywords

ADENINE; MOLECULAR SCAFFOLD; PURINERGIC P2X3 RECEPTOR; PURINERGIC P2X3 RECEPTOR ANTAGONIST; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; EMBRYO; HUMAN; HUMAN CELL; ION CURRENT; ISOMER; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PATCH CLAMP; SANDMEYER REACTION; SENSORY NERVE CELL; TRIGEMINUS GANGLION;

EID: 84884270343     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.04.037     Document Type: Article

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