Identification of negative residues in the P2X3 ATP receptor ectodomain as structural determinants for desensitization and the Ca 2+-sensing modulatory sites

Journal of Biological Chemistry

Volumn 279, Issue 51, 2004, Pages 53109-53115

  Fabbretti, Elsa ^a   Sokolova, Elena ^a   Masten, Lara ^a   D'Arco, Marianna ^a   Fabbro, Alessandra ^a   Nistri, Andrea ^a   Giniatullin, Rashid ^a  

^a SISSA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; CALCIUM; CELLS; PROTEINS;

DENSENSITIZATION; EMBRYONIC KIDNEY CELLS; NEURONS; PAIN SIGNALS;

NEUROLOGY;

ALANINE; ASPARTIC ACID; GLUTAMIC ACID; PURINE P2X3 RECEPTOR;

ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; EMBRYO CELL; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; KIDNEY CELL; MUTAGENESIS; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SEQUENCE; BLOTTING, WESTERN; CALCIUM; CATIONS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; OLIGONUCLEOTIDES; PATCH-CLAMP TECHNIQUES; PLASMIDS; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PURINERGIC P2; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 11144241633     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409772200     Document Type: Article

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