Effects of antibiotic therapy on the gastrointestinal microbiota and the influence of Lactobacillus casei

Food and Agricultural Immunology

Volumn 24, Issue 3, 2013, Pages 315-330

  Pirker, Angelika ^a   Stockenhuber, Alexander ^b   Remely, Marlene ^a   Harrant, Anna ^a   Hippe, Berit ^a   Kamhuber, Christoph ^b   Adelmann, Krista ^b   Stockenhuber, Felix ^b   Haslberger, Alexander G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Krankenhaus Oberpullendorf   (Austria)

Author keywords

antibiotic associated diarrhoea; antibiotics; bacterial; Clostridium difficile infection; gastrointestinal microbiota; Lactobacillus casei

Indexed keywords

EID: 84884263189     PISSN: 09540105     EISSN: 14653443     Source Type: Journal    
DOI: 10.1080/09540105.2012.689816     Document Type: Article

References (56)

1. Alcala, L., Sanchez-Cambronero, L., Catalan, M.P., Sanchez-Somolinos, M., Peláez, M.T., Marín, M., et al. (2008). Comparison of three commercial methods for rapid detection of Clostridium difficile toxins A and B from fecal specimens. Journal of Clinical Microbiology, 46(11), 3833-3835.
2. Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D.R., et al. (2011). Enterotypes of the human gut microbiome. Nature, 473(7346), 174-180.
3. Backhed, F., Ley, R.E., Sonnenburg, J.L., Peterson, D.A., & Gordon, J.I. (2005). Host-bacterial mutualism in the human intestine. Science, 307(5717), 1915-1920.
4. Bartlett, C.L. (1987). Efficacy of different surveillance systems in detecting hospital-acquired infections. Chemioterapia, 6(3), 152-155.
5. Bian, L., Nagata, S., Asahara, T., Rahman, M.S., Ohta, T., Yuki, N., et al. (2011). Effects of the continuous intake of Lactobacillus casei strain Shirota-fermented milk on risk management of long-term inpatients at health service facilities for the elderly. International Journal of Probiotics and Prebiotics, 6(2), 123-132.
6. Breves, G., Faul, K., Schroder, B., Holst, H., Caspary, W.F., & Stein, J. (2000). Application of the colon-simulation technique for studying the effects of Saccharomyces boulardii on basic parameters of porcine cecal microbial metabolism disturbed by clindamycin. Digestion, 61(3), 193-200.
7. Canani, R.B., Costanzo, M.D., Leone, L., Pedata, M., Meli, R., & Calignano, A. (2011). Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World Journal of Gastroenterology, 17(12), 1519-1528.
8. De La Cochetiere, M.F., Durand, T., Lepage, P., Bourreille, A., Galmiche, J.P., & Dore, J. (2005). Resilience of the dominant human fecal microbiota upon short-course antibiotic challenge. Journal of Clinical Microbiology, 43(11), 5588-5592.
9. Dethlefsen, L., Eckburg, P.B., Bik, E.M., & Relman, D.A. (2006). Assembly of the human intestinal microbiota. Trends in Ecology and Evolution, 21(9), 517-523.
10. Dethlefsen, L., & Relman, D.A. (2011). Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proceedings of the National Academy of Sciences of the United States of America, 108(SUPPL. 1), 4554-4561.
11. Eastwood, K., Else, P., Charlett, A., & Wilcox, M. (2009). Comparison of nine commercially available Clostridium difficile toxin detection assays, a real-time PCR assay for C. difficile tcdB, and a glutamate dehydrogenase detection assay to cytotoxin testing and cytotoxigenic culture methods. Journal of Clinical Microbiology, 47(10), 3211-3217.
12. Eckburg, P.B., Bik, E.M., Bernstein, C.N., Purdom, E., Dethlefsen, L., Sargent, M., et al. (2005). Diversity of the human intestinal microbial flora. Science, 308(5728), 1635-1638.
13. Fredstrom, S.B., Lampe, J.W., Jung, H.J., & Slavin, J.L. (1994). Apparent fiber digestibility and fecal short-chain fatty acid concentrations with ingestion of two types of dietary fiber. JPEN Journal of Parenteral and Enteral Nutrition, 18(1), 14-19.
14. Gao, X.W., Mubasher, M., Fang, C.Y., Reifer, C., & Miller, L.E. (2010). Dose-response efficacy of a proprietary probiotic formula of Lactobacillus acidophilus CL1285 and Lactobacillus casei LBC80R for antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea prophylaxis in adult patients. American Journal of Gastroenterology, 105(7), 1636-1641.
15. Guilloteau, P., Martin, L., Eeckhaut, V., Ducatelle, R., Zabielski, R., & Van Immerseel, F. (2010). From the gut to the peripheral tissues: The multiple effects of butyrate. Nutrition Research Reviews, 23(2), 366-384.
16. Hamer, H.M., Jonkers, D., Venema, K., Vanhoutvin, S., Troost, F.J., & Brummer, R.J. (2008). Review article: the role of butyrate on colonic function. Alimentary Pharmacology and Therapeutics, 27(2), 104-119.
17. Hensgens, M.P., Goorhuis, A., Van Kinschot, C.M., Crobach, M.J., Harmanus, C., & Kuijper, E.J. (2011). Clostridium difficile infection in an endemic setting in the Netherlands. European Journal of Clinical Microbiology Infectious Diseases, 30(4), 587-593.
18. Hickson, M., D'souza, A.L., Muthu, N., Rogers, T.R., Want, S., Rajkumar, C., et al. (2007). Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ, 335(7610), 80.
19. Hippe, B., Zwielehner, J., Liszt, K., Lassl, C., Unger, F., & Haslberger, A.G. (2011). Quantification of butyryl CoA:acetate CoA-transferase genes reveals different butyrate production capacity in individuals according to diet and age. FEMS Microbiology Letters, 316(2), 130-135.
20. Hogenauer, C., Hammer, H.F., Krejs, G.J., & Reisinger, E.C. (1998). Mechanisms and management of antibiotic-associated diarrhea. Clinical Infectious Diseases, 27(4), 702-710.
21. Jakobsson, H.E., Jernberg, C., Andersson, A.F., Sjolund-Karlsson, M., Jansson, J.K., & Engstrand, L. (2010). Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome. PLoS One, 5(3), e9836.
22. Kiwaki, M., & Kushiro, A. (2010). Antibiotic susceptibility testing of Lactobacillus casei by the broth microdilution method and a survey of vancomycin-resistance genes in the probiotic L. casei strain Shirota. Annual Report of Yakult Central Institute for Microbiological Research, 29, 27-36.
23. Lawley, T.D., Clare, S., Walker, A.W., Goulding, D., Stabler, R.A., Croucher, N., et al. (2009). Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infection and Immunity, 77(9), 3661-3669.
24. Lay, C., Sutren, M., Rochet, V., Saunier, K., Dore, J., & Rigottier-Gois, L. (2005). Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota. Environmental Microbiology, 7(7), 933-946.
25. Layton, A., Mckay, L., Williams, D., Garrett, V., Gentry, R., & Sayler, G. (2006). Development of Bacteroides 16S rRNA gene TaqMan-based real-time PCR assays for estimation of total, human, and bovine fecal pollution in water. Applied and Environmental Microbiology, 72(6), 4214-4224.
26. Lewis, J.D.N., Thomas, L.V., & Weir, W. (2009). The potential of probiotic fermented milk products in reducing risk of antibiotic-associated diarrhoea and Clostridium difficile disease. International Journal of Dairy Technology, 62(4), 461-471.
27. Louis, P., & Flint, H.J. (2007). Development of a semiquantitative degenerate real-time PCR-based assay for estimation of numbers of butyryl-coenzyme A (CoA) CoA transferase genes in complex bacterial samples. Applied and Environmental Microbiology, 73(6), 2009-2012.
28. Luna, R.A., Boyanton, B.L., Jr., Mehta, S., Courtney, E.M., Webb, C.R., Revell, P.A., et al. (2011). Rapid stool-based diagnosis of Clostridium difficile infection by real-time PCR in a children's hospital. Journal of Clinical Microbiology, 49(3), 851-857.
29. Martinez, C.O., Paz, V.S., & O'Donnell, A. (2003). Lactobacillus casei Shirota prevention approach for healthy children with mild acute infection treated with antibiotics. Pediatric Research, 4(SUPPL. 2), 174A.
30. Matsuki, T., Watanabe, K., Fujimoto, J., Takada, T., & Tanaka, R. (2004). Use of 16S rRNA gene-targeted group-specific primers for real-time PCR analysis of predominant bacteria in human feces. Applied and Environmental Microbiology, 70(12), 7220-7228.
31. McFarland, L.V. (2006). Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. American Journal of Gastroenterology, 101(4), 812-822.
32. McFarland, L.V. (2010). Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World Journal of Gastroenterology, 16(18), 2202-2222.
33. Mcfarland, L.V., Beneda, H.W., Clarridge, J.E., & Raugi, G.J. (2007). Implications of the changing face of Clostridium difficile disease for health care practitioners. American Journal of Infection Control, 35(4), 237-253.
34. Meier, H., Amann, R., Ludwig, W., & Schleifer, K.H. (1999). Specific oligonucleotide probes for in situ detection of a major group of gram-positive bacteria with low DNA G + C content. Systematic and Applied Microbiology, 22(2), 186-196.
35. Muyzer, G., de Waal, E.C., & Uitterlinden, A.G. (1993). Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Applied and Environmental Microbiology, 59(3), 695-700.
36. Muyzer, G., & Smalla, K. (1998). Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology. Antonie Van Leeuwenhoek, 73(1), 127-141.
37. Nadal, I., Santacruz, A., Marcos, A., Warnberg, J., Garagorri, M., Moreno, L.A., et al. (2009). Shifts in clostridia, bacteroides and immunoglobulin-coating fecal bacteria associated with weight loss in obese adolescents. International Journal of Obesity (London), 33(7), 758-767.
38. Nagata, S., Asahara, T., Ohta, T., Yamada, T., Kondo, S., Bian, L., et al. (2011). Effect of the continuous intake of probiotic-fermented milk containing Lactobacillus casei strain Shirota on fever in a mass outbreak of norovirus gastroenteritis and the faecal microflora in a health service facility for the aged. British Journal of Nutrition, 106(4), 549-556.
39. Neefs, J.M., Van De Peer, Y., De Rijk, P., Goris, A., & De Wachter, R. (1991). Compilation of small ribosomal subunit RNA sequences. Nucleic Acids Research, 19(SUPPL.), 1987-2015.
40. Otsubo, M., Shimizu, T., Tanaka, R., Sawabe, T., Tajima, K., Yoshimizu, M., et al. (2002). Oligonucleotide probe for detecting Enterobacteriaceae by in situ hybridization. Journal of Applied Microbiology, 93(1), 60-68.
41. Penders, J., Vink, C., Driessen, C., London, N., Thijs, C., & Stobberingh, E.E. (2005). Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by real-time PCR. FEMS Microbiology Letters, 243(1), 141-147.
42. Pryde, S.E., Duncan, S.H., Hold, G.L., Stewart, C.S., & Flint, H.J. (2002). The microbiology of butyrate formation in the human colon. FEMS Microbiology Letters, 217(2), 133-139.
43. Singhi, S.C., & Baranwal, A. (2008). Probiotic use in the critically ill. Indian Journal of Pediatrics, 75(6), 621-627.
44. Snydman, D.R. (2008). The safety of probiotics. Clinical Infectious Diseases, 46(SUPPL. 2), S104-S111; discussion S144-S151.
45. Sommer, M.O., & Dantas, G. (2011). Antibiotics and the resistant microbiome. Current Opinion in Microbiology, 14, 556563.
46. Song, Y., Liu, C., & Finegold, S.M. (2004). Real-time PCR quantitation of clostridia in feces of autistic children. Applied and Environmental Microbiology, 70(11), 6459-6465.
47. Thompson-Chagoyan, O.C., Maldonado, J., & Gil, A. (2007). Colonization and impact of disease and other factors on intestinal microbiota. Digestive Diseases and Sciences, 52(9), 2069-2077.
48. Topping, D.L., & Clifton, P.M. (2001). Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides. Physiological Reviews, 81(3), 1031-1064.
49. Walter, J., Hertel, C., Tannock, G.W., Lis, C.M., Munro, K., & Hammes, W.P. (2001). Detection of Lactobacillus, Pediococcus, Leuconostoc, and Weissella species in human feces by using group-specific PCR primers and denaturing gradient gel electrophoresis. Applied and Environmental Microbiology, 67(6), 2578-2585.
50. Wang, X., Heazlewood, S.P., Krause, D.O., & Florin, T.H. (2003). Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis. Journal of Applied Microbiology, 95(3), 508-520.
51. Wenus, C., Goll, R., Loken, E.B., Biong, A.S., Halvorsen, D.S., & Florholmen, J. (2008). Prevention of antibiotic-associated diarrhoea by a fermented probiotic milk drink. European Journal of Clinical Nutrition, 62(2), 299-301.
52. Whelan, K., & Myers, C.E. (2010). Safety of probiotics in patients receiving nutritional support: A systematic review of case reports, randomized controlled trials, and nonrandomized trials. American Journal of Clinical Nutrition, 91(3), 687-703.
53. Woo, P.C., Leung, P.K., Leung, K.W., & Yuen, K.Y. (2000). Identification by 16S ribosomal RNA gene sequencing of an Enterobacteriaceae species from a bone marrow transplant recipient. Molecular Pathology, 53(4), 211-215.
54. Yu, Y., Lee, C., Kim, J., & Hwang, S. (2005). Group-specific primer and probe sets to detect methanogenic communities using quantitative real-time polymerase chain reaction. Biotechnology and Bioengineering, 89(6), 670-679.
55. Zhu, B., Wang, X., & Li, L. (2010). Human gut microbiome: the second genome of human body. Protein Cell, 1(8), 718-725.
56. Zwielehner, J., Liszt, K., Handschur, M., Lassl, C., Lapin, A., & Haslberger, A.G. (2009). Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly. Experimental Gerontology, 44(6-7), 440-446.