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Volumn 756, Issue 1-2, 2013, Pages 206-212

Biochemical DSB-repair model for mammalian cells in G1 and early S phases of the cell cycle

Author keywords

Biochemical model; Double strand break (DSB); DSB repair

Indexed keywords

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL TYPE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; EUCHROMATIN; FIBROBLAST; HETEROCHROMATIN; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IONIZING RADIATION; IRRADIATION; KINETICS; MAMMAL CELL; MASS ACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RADIATION DOSE;

EID: 84884203599     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.06.004     Document Type: Article
Times cited : (74)

References (64)
  • 1
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 2
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • Valerie K., Povirk L.F. Regulation and mechanisms of mammalian double-strand break repair. Oncogene 2003, 22:5792-5812.
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 4
    • 77955145610 scopus 로고    scopus 로고
    • Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation
    • Anderson J.A., Harper J.V., Cucinotta F.A., O'Neill P. Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation. Radiat. Res. 2010, 174:195-205.
    • (2010) Radiat. Res. , vol.174 , pp. 195-205
    • Anderson, J.A.1    Harper, J.V.2    Cucinotta, F.A.3    O'Neill, P.4
  • 6
    • 25444502657 scopus 로고    scopus 로고
    • Artemis links ATM to double strand break rejoining
    • Jeggo P.A., Lobrich M. Artemis links ATM to double strand break rejoining. Cell Cycle 2005, 4:359-362.
    • (2005) Cell Cycle , vol.4 , pp. 359-362
    • Jeggo, P.A.1    Lobrich, M.2
  • 7
    • 0030954272 scopus 로고    scopus 로고
    • Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events
    • Nikjoo H., ONeill P., Goodhead D.T., Terrissol M. Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events. Int. J. Radiat. Biol. 1997, 71:467-483.
    • (1997) Int. J. Radiat. Biol. , vol.71 , pp. 467-483
    • Nikjoo, H.1    ONeill, P.2    Goodhead, D.T.3    Terrissol, M.4
  • 9
    • 20644471358 scopus 로고    scopus 로고
    • Harmonising the response to DSBs: a new string in the ATM bow
    • Lobrich M., Jeggo P.A. Harmonising the response to DSBs: a new string in the ATM bow. DNA Repair 2005, 4:749-759.
    • (2005) DNA Repair , vol.4 , pp. 749-759
    • Lobrich, M.1    Jeggo, P.A.2
  • 10
    • 0025739820 scopus 로고
    • Kinetics of DNA double-strand break repair throughout the cell-cycle as assayed by pulsed field gel-electrophoresis in cho cells
    • Metzger L., Iliakis G. Kinetics of DNA double-strand break repair throughout the cell-cycle as assayed by pulsed field gel-electrophoresis in cho cells. Int. J. Radiat. Biol. 1991, 59:1325-1339.
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 1325-1339
    • Metzger, L.1    Iliakis, G.2
  • 11
    • 0034010901 scopus 로고    scopus 로고
    • Rejoining of DNA fragments produced by radiations of different linear energy transfer
    • Stenerlow B., Hoglund E., Carlsson J., Blomquist E. Rejoining of DNA fragments produced by radiations of different linear energy transfer. Int. J. Radiat. Biol. 2000, 76:549-557.
    • (2000) Int. J. Radiat. Biol. , vol.76 , pp. 549-557
    • Stenerlow, B.1    Hoglund, E.2    Carlsson, J.3    Blomquist, E.4
  • 13
    • 84870587195 scopus 로고    scopus 로고
    • The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage
    • Reynolds P., Anderson J.A., Harper J.V., Hill M.A., Botchway S.W., Parker A.W., O'Neill P. The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage. Nucleic Acids Res. 2012, 40:10821-10831.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10821-10831
    • Reynolds, P.1    Anderson, J.A.2    Harper, J.V.3    Hill, M.A.4    Botchway, S.W.5    Parker, A.W.6    O'Neill, P.7
  • 17
    • 84874608346 scopus 로고    scopus 로고
    • Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations
    • Robberecht C., Voet T., Esteki M.Z., Nowakowska B.A., Vermeesch J.R. Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations. Genome Res. 2013, 23:411-418.
    • (2013) Genome Res. , vol.23 , pp. 411-418
    • Robberecht, C.1    Voet, T.2    Esteki, M.Z.3    Nowakowska, B.A.4    Vermeesch, J.R.5
  • 18
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
    • McVey M., Lee S.E. MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet. 2008, 24:529-538.
    • (2008) Trends Genet. , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 19
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer W.D., Ehmsen K.T., Liu J. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 2010, 44:113-139.
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 21
    • 0035577796 scopus 로고    scopus 로고
    • Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase
    • Wang H.Y., Guan J., Wang H.C., Perrault A.R., Wang Y., Iliakis G. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase. Cancer Res. 2001, 61:8554-8563.
    • (2001) Cancer Res. , vol.61 , pp. 8554-8563
    • Wang, H.Y.1    Guan, J.2    Wang, H.C.3    Perrault, A.R.4    Wang, Y.5    Iliakis, G.6
  • 22
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • Saintigny Y., Delacote F., Vares G., Petitot F., Lambert S., Averbeck D., Lopez B.S. Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J. 2001, 20:3861-3870.
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1    Delacote, F.2    Vares, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6    Lopez, B.S.7
  • 23
    • 79956220705 scopus 로고    scopus 로고
    • Choosing the right path: does DNA-PK help make the decision?
    • Neal J.A., Meek K. Choosing the right path: does DNA-PK help make the decision?. Mutat. Res.-Fundam. Mol. Mech. Mut. 2011, 711:73-86.
    • (2011) Mutat. Res.-Fundam. Mol. Mech. Mut. , vol.711 , pp. 73-86
    • Neal, J.A.1    Meek, K.2
  • 24
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • Symington L.S., Gautier J. Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 2011, 45:247-271.
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 25
    • 58149308524 scopus 로고    scopus 로고
    • Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells
    • Han L., Yu K. Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells. J. Exp. Med. 2008, 205:2745-2753.
    • (2008) J. Exp. Med. , vol.205 , pp. 2745-2753
    • Han, L.1    Yu, K.2
  • 26
    • 69949173301 scopus 로고    scopus 로고
    • Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence
    • Iliakis G. Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence. Radiother. Oncol. 2009, 92:310-315.
    • (2009) Radiother. Oncol. , vol.92 , pp. 310-315
    • Iliakis, G.1
  • 28
    • 84870557741 scopus 로고    scopus 로고
    • Repair of the double-strand breaks induced by low energy electrons: a modelling approach
    • Taleei R., Nikjoo H. Repair of the double-strand breaks induced by low energy electrons: a modelling approach. Int. J. Radiat. Biol. 2012, 88:948-953.
    • (2012) Int. J. Radiat. Biol. , vol.88 , pp. 948-953
    • Taleei, R.1    Nikjoo, H.2
  • 29
    • 39749184636 scopus 로고    scopus 로고
    • Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining
    • Cucinotta F.A., Pluth J.M., Anderson J.A., Harper J.V., O'Neill P. Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining. Radiat. Res. 2008, 169:214-222.
    • (2008) Radiat. Res. , vol.169 , pp. 214-222
    • Cucinotta, F.A.1    Pluth, J.M.2    Anderson, J.A.3    Harper, J.V.4    O'Neill, P.5
  • 30
    • 84855368486 scopus 로고    scopus 로고
    • Stochastic modelling of DSB repair after photon and ion irradiation
    • Friedland W., Kundrat P., Jacob P. Stochastic modelling of DSB repair after photon and ion irradiation. Int. J. Radiat. Biol. 2012, 88:129-136.
    • (2012) Int. J. Radiat. Biol. , vol.88 , pp. 129-136
    • Friedland, W.1    Kundrat, P.2    Jacob, P.3
  • 31
    • 79952318238 scopus 로고    scopus 로고
    • Mechanistic simulation of radiation damage to DNA and its repair: on the track towards systems radiation biology modelling
    • Friedland W., Jacob P., Kundrat P. Mechanistic simulation of radiation damage to DNA and its repair: on the track towards systems radiation biology modelling. Radiat. Prot. Dosim. 2011, 143:542-548.
    • (2011) Radiat. Prot. Dosim. , vol.143 , pp. 542-548
    • Friedland, W.1    Jacob, P.2    Kundrat, P.3
  • 32
    • 77951782095 scopus 로고    scopus 로고
    • Stochastic simulation of DNA double-strand break repair by non-homologous end joining based on track structure calculations
    • Friedland W., Jacob P., Kundrat P. Stochastic simulation of DNA double-strand break repair by non-homologous end joining based on track structure calculations. Radiat. Res. 2010, 173:677-688.
    • (2010) Radiat. Res. , vol.173 , pp. 677-688
    • Friedland, W.1    Jacob, P.2    Kundrat, P.3
  • 33
    • 84876963792 scopus 로고    scopus 로고
    • The non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks: I. A mathematical model
    • Taleei R., Nikjoo H. The non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks: I. A mathematical model. Radiat. Res. 2013, 179:530-539.
    • (2013) Radiat. Res. , vol.179 , pp. 530-539
    • Taleei, R.1    Nikjoo, H.2
  • 34
    • 84876996259 scopus 로고    scopus 로고
    • The non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks: II. Application to damage induced by ultrasoft X-rays and low energy electrons
    • Taleei R., Girard P.M., Sankaranarayanan K., Nikjoo H. The non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks: II. Application to damage induced by ultrasoft X-rays and low energy electrons. Radiat. Res. 2013, 179:540-548.
    • (2013) Radiat. Res. , vol.179 , pp. 540-548
    • Taleei, R.1    Girard, P.M.2    Sankaranarayanan, K.3    Nikjoo, H.4
  • 35
    • 79952322134 scopus 로고    scopus 로고
    • A kinetic model of single-strand annealing for the repair of DNA double-strand breaks
    • Taleei R., Weinfeld M., Nikjoo H. A kinetic model of single-strand annealing for the repair of DNA double-strand breaks. Radiat. Prot. Dosim. 2011, 143:191-195.
    • (2011) Radiat. Prot. Dosim. , vol.143 , pp. 191-195
    • Taleei, R.1    Weinfeld, M.2    Nikjoo, H.3
  • 36
    • 84876967800 scopus 로고    scopus 로고
    • Single strand annealing mathematical model for double strand break repair
    • Taleei R., Weinfeld M., Nikjoo H. Single strand annealing mathematical model for double strand break repair. J. Mol. Eng. Syst. Biol. 2012, 1:1-10.
    • (2012) J. Mol. Eng. Syst. Biol. , vol.1 , pp. 1-10
    • Taleei, R.1    Weinfeld, M.2    Nikjoo, H.3
  • 37
    • 0033756415 scopus 로고    scopus 로고
    • Kinetics of DSB rejoining and formation of simple chromosome exchange aberrations
    • Cucinotta F.A., Nikjoo H., O'Neill P., Goodhead D.T. Kinetics of DSB rejoining and formation of simple chromosome exchange aberrations. Int. J. Radiat. Biol. 2000, 76:1463-1474.
    • (2000) Int. J. Radiat. Biol. , vol.76 , pp. 1463-1474
    • Cucinotta, F.A.1    Nikjoo, H.2    O'Neill, P.3    Goodhead, D.T.4
  • 39
    • 43449129745 scopus 로고    scopus 로고
    • Repair of radiation-induced heat-labile sites is independent of DNA-PKcs, XRCC1 and PARP
    • Karlsson K.H., Radulescu I., Rydberg B., Stenerlow B. Repair of radiation-induced heat-labile sites is independent of DNA-PKcs, XRCC1 and PARP. Radiat. Res. 2008, 169:506-512.
    • (2008) Radiat. Res. , vol.169 , pp. 506-512
    • Karlsson, K.H.1    Radulescu, I.2    Rydberg, B.3    Stenerlow, B.4
  • 41
    • 33845657443 scopus 로고    scopus 로고
    • PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
    • Wang M., Wu W., Rosidi B., Zhang L., Wang H., Iliakis G. PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Res. 2006, 34:6170-6182.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6170-6182
    • Wang, M.1    Wu, W.2    Rosidi, B.3    Zhang, L.4    Wang, H.5    Iliakis, G.6
  • 42
    • 4544362838 scopus 로고    scopus 로고
    • The mechanism of non-homologous end-joining: a synopsis of synapsis
    • Weterings E., van Gent D.C. The mechanism of non-homologous end-joining: a synopsis of synapsis. DNA Repair 2004, 3:1425-1435.
    • (2004) DNA Repair , vol.3 , pp. 1425-1435
    • Weterings, E.1    van Gent, D.C.2
  • 43
    • 28544448011 scopus 로고    scopus 로고
    • Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice
    • Cui X., Yu Y., Gupta S., Cho Y.M., Lees-Miller S.P., Meek K. Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice. Mol. Cell. Biol. 2005, 25:10842-10852.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10842-10852
    • Cui, X.1    Yu, Y.2    Gupta, S.3    Cho, Y.M.4    Lees-Miller, S.P.5    Meek, K.6
  • 44
  • 45
    • 34248231265 scopus 로고    scopus 로고
    • Trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining
    • Meek K., Douglas P., Cui X.P., Ding Q., Lees-Miller S.P. trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining. Mol. Cell. Biol. 2007, 27:3881-3890.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3881-3890
    • Meek, K.1    Douglas, P.2    Cui, X.P.3    Ding, Q.4    Lees-Miller, S.P.5
  • 46
    • 33847185190 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain
    • Douglas P., Cui X.P., Block W.D., Yu Y.P., Gupta S., Ding Q., Ye R.Q., Morrice N., Lees-Miller S.P., Meek K. The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain. Mol. Cell. Biol. 2007, 27:1581-1591.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1581-1591
    • Douglas, P.1    Cui, X.P.2    Block, W.D.3    Yu, Y.P.4    Gupta, S.5    Ding, Q.6    Ye, R.Q.7    Morrice, N.8    Lees-Miller, S.P.9    Meek, K.10
  • 47
    • 34347393519 scopus 로고    scopus 로고
    • Radiation-induced DNA damage responses
    • Jeggo P., Lobrich M. Radiation-induced DNA damage responses. Radiat. Prot. Dosim. 2006, 122:124-127.
    • (2006) Radiat. Prot. Dosim. , vol.122 , pp. 124-127
    • Jeggo, P.1    Lobrich, M.2
  • 48
    • 78649449767 scopus 로고    scopus 로고
    • The influence of heterochromatin on DNA double strand break repair: getting the strong, silent type to relax
    • Goodarzi A.A., Jeggo P., Lobrich M. The influence of heterochromatin on DNA double strand break repair: getting the strong, silent type to relax. DNA Repair 2010, 9:1273-1282.
    • (2010) DNA Repair , vol.9 , pp. 1273-1282
    • Goodarzi, A.A.1    Jeggo, P.2    Lobrich, M.3
  • 50
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
    • (2008) Mol. Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6    Jeggo, P.A.7
  • 51
    • 77957369329 scopus 로고    scopus 로고
    • Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in drosophila
    • Chan S.H., Yu A.M., Mcvey M. Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in drosophila. PLoS Genet. 2010, 6.
    • (2010) PLoS Genet. , vol.6
    • Chan, S.H.1    Yu, A.M.2    Mcvey, M.3
  • 54
    • 30744469845 scopus 로고    scopus 로고
    • Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway
    • Audebert M., Salles B., Weinfeld M., Calsou P. Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway. J. Mol. Biol. 2006, 356:257-265.
    • (2006) J. Mol. Biol. , vol.356 , pp. 257-265
    • Audebert, M.1    Salles, B.2    Weinfeld, M.3    Calsou, P.4
  • 55
    • 41149149754 scopus 로고    scopus 로고
    • Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway
    • Audebert M., Salles B., Calsou P. Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway. Biochem. Biophys. Res. Commun. 2008, 369:982-988.
    • (2008) Biochem. Biophys. Res. Commun. , vol.369 , pp. 982-988
    • Audebert, M.1    Salles, B.2    Calsou, P.3
  • 57
    • 84863202793 scopus 로고    scopus 로고
    • Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases lambda and beta on normal and repetitive DNA sequences
    • Crespan E., Czabany T., Maga G., Hubscher U. Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases lambda and beta on normal and repetitive DNA sequences. Nucleic Acids Res. 2012, 40:5577-5590.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 5577-5590
    • Crespan, E.1    Czabany, T.2    Maga, G.3    Hubscher, U.4
  • 58
    • 0035953402 scopus 로고    scopus 로고
    • Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group
    • Wang H., Zeng Z.C., Bui T.A., Sonoda E., Takata M., Takeda S., Iliakis G. Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group. Oncogene 2001, 20:2212-2224.
    • (2001) Oncogene , vol.20 , pp. 2212-2224
    • Wang, H.1    Zeng, Z.C.2    Bui, T.A.3    Sonoda, E.4    Takata, M.5    Takeda, S.6    Iliakis, G.7
  • 59
    • 0035870583 scopus 로고    scopus 로고
    • Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells
    • Wang H., Zeng Z.C., Perrault A.R., Cheng X., Qin W., Iliakis G. Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells. Nucleic Acids Res. 2001, 29:1653-1660.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1653-1660
    • Wang, H.1    Zeng, Z.C.2    Perrault, A.R.3    Cheng, X.4    Qin, W.5    Iliakis, G.6
  • 61
    • 0031756124 scopus 로고    scopus 로고
    • Joining of correct and incorrect DNA ends at double-strand breaks produced by high-linear energy transfer radiation in human fibroblasts
    • Lobrich M., Cooper P.K., Rydberg B. Joining of correct and incorrect DNA ends at double-strand breaks produced by high-linear energy transfer radiation in human fibroblasts. Radiat. Res. 1998, 150:619-626.
    • (1998) Radiat. Res. , vol.150 , pp. 619-626
    • Lobrich, M.1    Cooper, P.K.2    Rydberg, B.3
  • 63
    • 37549006429 scopus 로고    scopus 로고
    • Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2
    • Wu W., Wang M., Wu W., Singh S.K., Mussfeldt T., Iliakis G. Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2. DNA Repair 2008, 7:329-338.
    • (2008) DNA Repair , vol.7 , pp. 329-338
    • Wu, W.1    Wang, M.2    Wu, W.3    Singh, S.K.4    Mussfeldt, T.5    Iliakis, G.6
  • 64
    • 0026087508 scopus 로고
    • Measurement of DNA double-strand breaks in cho cells at various stages of the cell-cycle using pulsed field gel-electrophoresis - calibration by means of I-125 decay
    • Iliakis G.E., Cicilioni O., Metzger L. Measurement of DNA double-strand breaks in cho cells at various stages of the cell-cycle using pulsed field gel-electrophoresis - calibration by means of I-125 decay. Int. J. Radiat. Biol. 1991, 59:343-357.
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 343-357
    • Iliakis, G.E.1    Cicilioni, O.2    Metzger, L.3


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