Kinetics of DSB rejoining and formation of simple chromosome exchange aberrations

International Journal of Radiation Biology

Volumn 76, Issue 11, 2000, Pages 1463-1474

  Cucinotta, F A ^a   Nikjoo, H ^a   O'Neill, P ^a   Goodhead, D T ^a  

^a NASA HEADQUARTERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CALCULATION; CHROMOSOME ABERRATION; COMPUTER SIMULATION; DNA REPAIR; DNA STRAND BREAKAGE; KINETICS; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PRIORITY JOURNAL; RADIATION INJURY; X IRRADIATION;

EID: 0033756415     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000050176225     Document Type: Article

References (57)

1. DNA double-strand break repair determines the RBE of α-particles
2. Induction and rejoining of DNA double-strand breaks in Chinese hamster V79-4 cells irradiated with characteristic aluminum K and copper L ultrasoft X rays
3. Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks
4. The rejoining of DNA double strand breaks and a model for the formation of chromosomal aberrations
5. On the dose-effect relationship of true simple chromosomal rearrangements. Comments on the paper: Simple chromosome exchanges are not linear with dose
6. Testing the notion of one hit exchange
7. The effects of dimethyl sulfoxide on the induction of DNA double-strand breaks in V79-4 mammalian cells by alpha particles
8. Rearrangement of human cell homologous chromosome domains in response to ionizing radiation
9. Rejoining and misrejoining of radiation-induced chromatin breaks. I. Experiments with human lymphocytes
10. Two alternate pathways of double strand break repair that are kinetically separable and independently modulated
11. Dose-rate effect of radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line
12. Repair of radiation-induced DNA double strand breaks in human fibroblasts is consistent with a continuous spectrum of repair probabilities
13. Is repair of DNA strand break damage from ionizing radiation second-order rather than first-order?
14. Induction, repair and biological evidence of radiation-induced DNA lesions in eukaryotic cells
15. A comparative study of rejoining of DNA double-strand breaks in yeast irradiated with 3.5MeV α-particles or with 30 MeV electrons
16. Saturable repair models of radiation action in mammalian cells
17. Track-structure analysis of ultra-soft x-rays compared with high and low LET radiations
18. Clustered damage in DNA: Estimates from track-structure simulations
19. Effectiveness of 0.3 keV carbon ultrasoft X-rays for the inactivation and mutation of cultured mammalian cells
20. Effects of radiation of different qualities on cells: Molecular mechanisms of damage and repair
21. Ultrasoft X-rays as a tool to investigate radiation-induced dicentric chromosome aberrations
22. Kinetics of the formation of chromosome aberrations in X-irradiated human lymphocytes: Analysis by premature chromosome condensation with delayed fusion
23. Chromosome aberrations induced in human lymphocytes by 3.45 MeV alpha particles analyzed by premature chromosome condensation
24. Comparative study of the repair kinetics of chromosomal aberrations and DNA strand breaks in proliferating and quiescent CHO cells
25. Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblasts in vitro detected using FISH
26. Ultrasoft 1.5 keV aluminum K X rays are efficient producers of complex chromosome exchange aberrations as revealed by fluorescence in situ hybridization
27. DNA repair: Stranded in an active gene
28. Effectiveness of carbon ultrasoft X rays at inducing complex exchanges in human fibroblasts
29. Identification of genes involved in repair of DNA double-strand breaks in mammalian cells
30. The induction and joining of DNA double strand breaks in V79-4 mammalian cells under aerobic and hypoxic conditions by γ and α radiations
31. The induction of DNA double strand breaks in V79-4 cells by γ and α radiations complexity of damage
32. Recombination and joining: Different means to the same ends
33. A repair fixation model based on classical enzyme kinetics
34. Relative contribution of levels of initial DNA damage and repair of double stand breaks to the ionizing radiation-sensitive phenotype of the Chines hamster cell mutant, XR-V15B. Part I. X-rays
35. Deoxyribonucleoprotein structure and radiation injury: Cellular radiation sensitivity is determined by LETω-dependent DNA damage in hydrated deoxyribonucleoproteins and the extent of its repair
36. Chromosomal double-strand break repair in Ku80-deficient cells
37. Joining of correct and incorrect DNA ends at double strand breaks produced by high linear energy transfer radiation in human fibroblasts
38. Induction and repair of DNA double-strand breaks in the same dose range as the shoulder of the survival curve
39. Computational modeling of low-energy electron-induced DNA damage by early physical and chemical events
40. Quantitative modelling of DNA damage using Monte Carlo track-structure method
41. The repair of double-stand breaks in DNA: A model involving recombination
42. Mechanisms of nonhomologous recombination in mammalian cells
43. A brief survey of aberration origin theories
44. Comment on reply to letter from Chadwick and Leenhouts: On the dose-effect relationship of true simple chromosomal rearrangements
45. The quasi-steady-state assumption: A case study in perturbation
46. Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected using fluorescence in situ hybridization
47. RecA-dependent DNA repair processes
48. A cell survival model with saturable repair after irradiation
49. The double-strand break repair model for recombination
50. The study of responses to 'model' DNA breaks induced by restriction endonucleases in cells and cell-free systems: Achievements and difficulties
51. The induction of chromosome exchange aberrations by carbon ultrasoft X-rays in V79 hamster cells
52. Chromosome aberrations induced in human lymphocytes by ultrasoft Al-k and Cu X-rays
53. Topological requirements for homologous among DNA molecules transfected into mammalian cells
54. DNA repair kinetics in irradiated undifferentiated and terminally differentiated cells
55. DNA repair kinetics in mammalian cells following split-dose irradiation
56. Rejoining and misrejoining of radiation-induced chromatin breaks. II. Biophysical model