메뉴 건너뛰기




Volumn 4, Issue JUL, 2013, Pages

Ghrelin receptors in non-mammalian vertebrates

Author keywords

Amphibians; Birds; Fishes; Ghrelin; Ghrelin receptor; GHS R; GHS R like receptor; Reptiles

Indexed keywords

CORTICOSTERONE; DEXAMETHASONE; GHRELIN; GHRELIN RECEPTOR; GLUCOCORTICOID; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; INOSITOL TRISPHOSPHATE; LEPTIN; LUTEINIZING HORMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROTENSIN RECEPTOR; NUCLEAR FACTOR I; OCTAMER TRANSCRIPTION FACTOR 1; PHOSPHOLIPASE C; PROTEIN KINASE C; SOMATOMEDIN C; THYROID HORMONE; TRANSCRIPTION FACTOR AP 1; UPSTREAM STIMULATORY FACTOR;

EID: 84884201165     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2013.00081     Document Type: Review
Times cited : (34)

References (100)
  • 1
    • 0035085142 scopus 로고    scopus 로고
    • Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin
    • doi:10.1385/ENDO:14:1:021
    • Tannenbaum GS, Bowers CY. Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin. Endocrine (2001) 14:21-7. doi:10.1385/ENDO:14:1:021
    • (2001) Endocrine , vol.14 , pp. 21-27
    • Tannenbaum, G.S.1    Bowers, C.Y.2
  • 2
    • 14144254610 scopus 로고    scopus 로고
    • Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men
    • doi:10.1210/jc.2004-1719
    • Laferrère B, Abraham C, Russell CD, Bowers CY. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab (2005) 90:611-4. doi:10.1210/jc.2004-1719
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 611-614
    • Laferrère, B.1    Abraham, C.2    Russell, C.D.3    Bowers, C.Y.4
  • 3
    • 9444246501 scopus 로고    scopus 로고
    • A receptor in pituitary and hypothalamus that functions in growth hormone release
    • doi:10.1126/science.273.5277.974
    • Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science (1996) 273:974-7. doi:10.1126/science.273.5277.974
    • (1996) Science , vol.273 , pp. 974-977
    • Howard, A.D.1    Feighner, S.D.2    Cully, D.F.3    Arena, J.P.4    Liberator, P.A.5    Rosenblum, C.I.6
  • 4
    • 0031003664 scopus 로고    scopus 로고
    • Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors
    • doi:10.1210/me.11.4.415
    • McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, et al. Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol Endocrinol (1997) 11:415-23. doi:10.1210/me.11.4.415
    • (1997) Mol Endocrinol , vol.11 , pp. 415-423
    • McKee, K.K.1    Palyha, O.C.2    Feighner, S.D.3    Hreniuk, D.L.4    Tan, C.P.5    Phillips, M.S.6
  • 5
    • 0036977178 scopus 로고    scopus 로고
    • Structure and regulation of the growth hormone secretagogue receptor
    • Petersenn S. Structure and regulation of the growth hormone secretagogue receptor. Minerva Endocrinol (2002) 27:243-56.
    • (2002) Minerva Endocrinol , vol.27 , pp. 243-256
    • Petersenn, S.1
  • 6
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide
    • doi:10.1038/45230
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matuso H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide. Nature (1999) 402:656-60. doi:10.1038/45230
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matuso, H.5    Kangawa, K.6
  • 7
    • 77955417391 scopus 로고    scopus 로고
    • The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine
    • doi:10.1016/j.bmc.2010.06.062
    • Großauer J, Kosol S, Schrank E, Zangger K. The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine. Bioorg Med Chem (2010) 18:5483-8. doi:10.1016/j.bmc.2010.06.062
    • (2010) Bioorg Med Chem , vol.18 , pp. 5483-5488
    • Großauer, J.1    Kosol, S.2    Schrank, E.3    Zangger, K.4
  • 8
    • 33747625691 scopus 로고    scopus 로고
    • Biological, physiological, and pharmacological aspects of ghrelin
    • doi:10.1254/jphs.CRJ06002X
    • Hosoda H, Kojima M, Kangawa K. Biological, physiological, and pharmacological aspects of ghrelin. J Pharmacol Sci (2006) 100:398-410. doi:10.1254/jphs.CRJ06002X
    • (2006) J Pharmacol Sci , vol.100 , pp. 398-410
    • Hosoda, H.1    Kojima, M.2    Kangawa, K.3
  • 9
    • 73449090824 scopus 로고    scopus 로고
    • Ghrelin gene products and the regulation of food intake and gut motility
    • doi:10.1124/pr.109.001958
    • Chen CY, Asakawa A, Fujimiya M, Lee SD, Inui A. Ghrelin gene products and the regulation of food intake and gut motility. Pharmacol Rev (2009) 61:430-81. doi:10.1124/pr.109.001958
    • (2009) Pharmacol Rev , vol.61 , pp. 430-481
    • Chen, C.Y.1    Asakawa, A.2    Fujimiya, M.3    Lee, S.D.4    Inui, A.5
  • 10
    • 77954591294 scopus 로고    scopus 로고
    • Ghrelin: more than endogenous growth hormone secretagogue
    • doi:10.1111/j.1749-6632.2010.05516.x
    • Kojima M, Kangawa K. Ghrelin: more than endogenous growth hormone secretagogue. Ann N Y Acad Sci (2010) 1200:140-8. doi:10.1111/j.1749-6632.2010.05516.x
    • (2010) Ann N Y Acad Sci , vol.1200 , pp. 140-148
    • Kojima, M.1    Kangawa, K.2
  • 11
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • doi:10.1210/endo-114-5-1537
    • Bowers CY, Momany FA, Reynolds GA, Hong A. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology (1984) 114:1537-45. doi:10.1210/endo-114-5-1537
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 12
    • 0031950553 scopus 로고    scopus 로고
    • Pituitary and extrapituitary action sites of the novel nonpeptidyl growth hormone (GH) secretagogue L-692,429 in the chicken
    • doi:10.1006/gcen.1998.7102
    • Geris KL, Hickey GJ, Berghman LR, Visser TJ, Kühn ER, Darras VM. Pituitary and extrapituitary action sites of the novel nonpeptidyl growth hormone (GH) secretagogue L-692,429 in the chicken. Gen Comp Endocrinol (1998) 111:186-96. doi:10.1006/gcen.1998.7102
    • (1998) Gen Comp Endocrinol , vol.111 , pp. 186-196
    • Geris, K.L.1    Hickey, G.J.2    Berghman, L.R.3    Visser, T.J.4    Kühn, E.R.5    Darras, V.M.6
  • 13
    • 0035081585 scopus 로고    scopus 로고
    • Synthetic growth hormone secretagogues control growth hormone secretion in the chicken at pituitary and hypothalamic levels
    • doi:10.1385/ENDO:14:1:067
    • Geris KL, Hickey GJ, Vanderghote A, Kühn ER, Darras VM. Synthetic growth hormone secretagogues control growth hormone secretion in the chicken at pituitary and hypothalamic levels. Endocrine (2001) 14:67-72. doi:10.1385/ENDO:14:1:067
    • (2001) Endocrine , vol.14 , pp. 67-72
    • Geris, K.L.1    Hickey, G.J.2    Vanderghote, A.3    Kühn, E.R.4    Darras, V.M.5
  • 14
    • 0034522016 scopus 로고    scopus 로고
    • The hexapeptide KP-102 (D-Ala-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH(2)) stimulates growth hormone release in a cichlid fish (Oreochromis mossambicus)
    • doi:10.1677/joe.0.167R007
    • Shepherd BS, Eckert SM, Parhar IS, Vijayan MM, Wakabayashi I, Hirano T, et al. The hexapeptide KP-102 (D-Ala-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH(2)) stimulates growth hormone release in a cichlid fish (Oreochromis mossambicus). J Endocrinol (2000) 167:R7-10. doi:10.1677/joe.0.167R007
    • (2000) J Endocrinol , vol.167
    • Shepherd, B.S.1    Eckert, S.M.2    Parhar, I.S.3    Vijayan, M.M.4    Wakabayashi, I.5    Hirano, T.6
  • 15
    • 0035798584 scopus 로고    scopus 로고
    • Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue
    • doi:10.1074/jbc.M105212200
    • Kaiya H, Kojima M, Hosoda H, Koda A, Yamamoto K, Kitajima Y, et al. Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue. J Biol Chem (2001) 276:40441-8. doi:10.1074/jbc.M105212200
    • (2001) J Biol Chem , vol.276 , pp. 40441-40448
    • Kaiya, H.1    Kojima, M.2    Hosoda, H.3    Koda, A.4    Yamamoto, K.5    Kitajima, Y.6
  • 17
    • 81755172032 scopus 로고    scopus 로고
    • Recent advances in the phylogenetic study of ghrelin
    • doi:10.1016/j.peptides.2011.04.027
    • Kaiya H, Miyazato M, Kangawa K. Recent advances in the phylogenetic study of ghrelin. Peptides (2011) 32:2155-74. doi:10.1016/j.peptides.2011.04.027
    • (2011) Peptides , vol.32 , pp. 2155-2174
    • Kaiya, H.1    Miyazato, M.2    Kangawa, K.3
  • 19
    • 84873058411 scopus 로고    scopus 로고
    • Ghrelin receptor in two species of anuran amphibian, bullfrog (Rana catesbeiana), and Japanese tree frog (Hyla japonica)
    • doi:10.3389/fendo.2011.00031
    • Kaiya H, Koizumi Y, Konno N, Yamamoto K, Uchiyama M, Kangawa K, et al. Ghrelin receptor in two species of anuran amphibian, bullfrog (Rana catesbeiana), and Japanese tree frog (Hyla japonica). Front Endocrinol (Lausanne) (2011) 2:31. doi:10.3389/fendo.2011.00031
    • (2011) Front Endocrinol (Lausanne) , vol.2 , pp. 31
    • Kaiya, H.1    Koizumi, Y.2    Konno, N.3    Yamamoto, K.4    Uchiyama, M.5    Kangawa, K.6
  • 20
    • 0032733930 scopus 로고    scopus 로고
    • Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions
    • doi:10.1016/S0955-0674(99)00039-3
    • Meyer A, Schartl M. Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions. Curr Opin Cell Biol (1999) 11:699-704. doi:10.1016/S0955-0674(99)00039-3
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 699-704
    • Meyer, A.1    Schartl, M.2
  • 21
    • 7244259101 scopus 로고    scopus 로고
    • Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype
    • doi:10.1038/nature03025
    • Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, et al. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature (2004) 431:946-57. doi:10.1038/nature03025
    • (2004) Nature , vol.431 , pp. 946-957
    • Jaillon, O.1    Aury, J.M.2    Brunet, F.3    Petit, J.L.4    Stange-Thomann, N.5    Mauceli, E.6
  • 22
    • 77955414264 scopus 로고    scopus 로고
    • Two functional growth hormone secretagogue receptor (ghrelin receptor) type 1a and 2a in goldfish, Carassius auratus
    • doi:10.1016/j.mce.2010.06.004
    • Kaiya H, Miura T, Matsuda K, Miyazato M, Kangawa K. Two functional growth hormone secretagogue receptor (ghrelin receptor) type 1a and 2a in goldfish, Carassius auratus. Mol Cell Endocrinol (2010) 327:25-39. doi:10.1016/j.mce.2010.06.004
    • (2010) Mol Cell Endocrinol , vol.327 , pp. 25-39
    • Kaiya, H.1    Miura, T.2    Matsuda, K.3    Miyazato, M.4    Kangawa, K.5
  • 23
    • 65649106614 scopus 로고    scopus 로고
    • Ghrelin receptor (GHS-R)-like receptor and its genomic organisation in rainbow trout, Oncorhynchus mykiss
    • doi:10.1016/j.cbpa.2009.04.612
    • Kaiya H, Mori T, Miyazato M, Kangawa K. Ghrelin receptor (GHS-R)-like receptor and its genomic organisation in rainbow trout, Oncorhynchus mykiss. Comp Biochem Physiol A Mol Integr Physiol (2009) 153:438-50. doi:10.1016/j.cbpa.2009.04.612
    • (2009) Comp Biochem Physiol A Mol Integr Physiol , vol.153 , pp. 438-450
    • Kaiya, H.1    Mori, T.2    Miyazato, M.3    Kangawa, K.4
  • 24
    • 4344683314 scopus 로고    scopus 로고
    • Occurrence of polyploidy in the fishes
    • doi:10.1023/B:RFBF.0000033049.00668.fe
    • Leggatt RA, Iwama GK. Occurrence of polyploidy in the fishes. NULL (2003) 13:237-46. doi:10.1023/B:RFBF.0000033049.00668.fe
    • (2003) , vol.13 , pp. 237-246
    • Leggatt, R.A.1    Iwama, G.K.2
  • 25
    • 84856258901 scopus 로고    scopus 로고
    • Opsin gene duplication and divergence in ray-finned fish
    • doi:10.1016/j.ympev.2011.11.030
    • Rennison DJ, Owens GL, Taylor JS. Opsin gene duplication and divergence in ray-finned fish. Mol Phylogenet Evol (2012) 62:986-1008. doi:10.1016/j.ympev.2011.11.030
    • (2012) Mol Phylogenet Evol , vol.62 , pp. 986-1008
    • Rennison, D.J.1    Owens, G.L.2    Taylor, J.S.3
  • 26
    • 63449112753 scopus 로고    scopus 로고
    • Identification and genomic sequence of a ghrelin receptor (GHS-R)-like receptor in the Mozambique tilapia, Oreochromis mossambicus
    • doi:10.2108/zsj.26.330
    • Kaiya H, Riley LG, Janzen W, Hirano T, Grau EG, Miyazato M, et al. Identification and genomic sequence of a ghrelin receptor (GHS-R)-like receptor in the Mozambique tilapia, Oreochromis mossambicus. Zool Sci (2009) 26:330-7. doi:10.2108/zsj.26.330
    • (2009) Zool Sci , vol.26 , pp. 330-337
    • Kaiya, H.1    Riley, L.G.2    Janzen, W.3    Hirano, T.4    Grau, E.G.5    Miyazato, M.6
  • 27
    • 17744384915 scopus 로고    scopus 로고
    • Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from pufferfish to humans
    • doi:10.1210/me.14.1.160
    • Palyha OC, Feighner SD, Tan CP, McKee KK, Hreniuk DL, Gao YD, et al. Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from pufferfish to humans. Mol Endocrinol (2000) 14:160-9. doi:10.1210/me.14.1.160
    • (2000) Mol Endocrinol , vol.14 , pp. 160-169
    • Palyha, O.C.1    Feighner, S.D.2    Tan, C.P.3    McKee, K.K.4    Hreniuk, D.L.5    Gao, Y.D.6
  • 28
    • 1142285486 scopus 로고    scopus 로고
    • Identification and functional characterization of two alternatively spliced growth hormone secretagogue receptor transcripts from the pituitary of black seabream, Acanthopagrus schlegeli
    • doi:10.1016/j.mce.2003.11.020
    • Chan CB, Cheng CH. Identification and functional characterization of two alternatively spliced growth hormone secretagogue receptor transcripts from the pituitary of black seabream, Acanthopagrus schlegeli. Mol Cell Endocrinol (2004) 214:81-95. doi:10.1016/j.mce.2003.11.020
    • (2004) Mol Cell Endocrinol , vol.214 , pp. 81-95
    • Chan, C.B.1    Cheng, C.H.2
  • 29
    • 0141570796 scopus 로고    scopus 로고
    • Distribution and regulation of chicken growth hormone secretagogue receptor isoforms
    • doi:10.1016/S0016-6480(03)00250-8
    • Geelissen SM, Beck IM, Darras VM, Kühn ER, Van der Geyten S. Distribution and regulation of chicken growth hormone secretagogue receptor isoforms. Gen Comp Endocrinol (2003) 134:167-74. doi:10.1016/S0016-6480(03)00250-8
    • (2003) Gen Comp Endocrinol , vol.134 , pp. 167-174
    • Geelissen, S.M.1    Beck, I.M.2    Darras, V.M.3    Kühn, E.R.4    Van der Geyten, S.5
  • 30
    • 0141459155 scopus 로고    scopus 로고
    • Molecular characterization of chicken growth hormone secretagogue receptor gene
    • doi:10.1016/S0016-6480(03)00247-8
    • Tanaka M, Miyazaki T, Yamamoto I, Nakai N, Ohta Y, Tsushima N, et al. Molecular characterization of chicken growth hormone secretagogue receptor gene. Gen Comp Endocrinol (2003) 134:198-202. doi:10.1016/S0016-6480(03)00247-8
    • (2003) Gen Comp Endocrinol , vol.134 , pp. 198-202
    • Tanaka, M.1    Miyazaki, T.2    Yamamoto, I.3    Nakai, N.4    Ohta, Y.5    Tsushima, N.6
  • 32
    • 70349739079 scopus 로고    scopus 로고
    • Molecular cloning of growth hormone secretagogue-receptor and effect of quail ghrelin on gastrointestinal motility in Japanese quail
    • doi:10.1016/j.regpep.2009.07.005
    • Kitazawa T, Maeda Y, Kaiya H. Molecular cloning of growth hormone secretagogue-receptor and effect of quail ghrelin on gastrointestinal motility in Japanese quail. Regul Pept (2009) 158:132-42. doi:10.1016/j.regpep.2009.07.005
    • (2009) Regul Pept , vol.158 , pp. 132-142
    • Kitazawa, T.1    Maeda, Y.2    Kaiya, H.3
  • 33
    • 79961140986 scopus 로고    scopus 로고
    • The avian proghrelin system
    • doi:10.1155/2010/749401
    • Richards MP, McMurtry JP. The avian proghrelin system. Int J Pept (2010) 2010:749401. doi:10.1155/2010/749401
    • (2010) Int J Pept , vol.2010 , pp. 749401
    • Richards, M.P.1    McMurtry, J.P.2
  • 34
    • 3042735648 scopus 로고    scopus 로고
    • The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
    • doi:10.1210/jc.87.6.2988
    • Gnanapavan S, Kola B, Bustin SA, Morris DG, McGee P, Fairclough P, et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab (2002) 87:2988-91. doi:10.1210/jc.87.6.2988
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2988-2991
    • Gnanapavan, S.1    Kola, B.2    Bustin, S.A.3    Morris, D.G.4    McGee, P.5    Fairclough, P.6
  • 35
    • 33847081784 scopus 로고    scopus 로고
    • Ghrelin and growth hormone secretagogue receptor expression in mice during aging
    • doi:10.1210/en.2006-0782
    • Sun Y, Garcia JM, Smith RG. Ghrelin and growth hormone secretagogue receptor expression in mice during aging. Endocrinology (2007) 148:1323-9. doi:10.1210/en.2006-0782
    • (2007) Endocrinology , vol.148 , pp. 1323-1329
    • Sun, Y.1    Garcia, J.M.2    Smith, R.G.3
  • 36
    • 70649098385 scopus 로고    scopus 로고
    • Expression of ghrelin and its receptor in human tissues
    • doi:10.1055/s-0029-1233462
    • Ueberberg B, Unger N, Saeger W, Mann K, Petersenn S. Expression of ghrelin and its receptor in human tissues. Horm Metab Res (2009) 1:814-21. doi:10.1055/s-0029-1233462
    • (2009) Horm Metab Res , vol.1 , pp. 814-821
    • Ueberberg, B.1    Unger, N.2    Saeger, W.3    Mann, K.4    Petersenn, S.5
  • 37
    • 0030762351 scopus 로고    scopus 로고
    • Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
    • doi:10.1016/S0169-328X(97)00071-5
    • Guan XM, Yu H, Palyha OC, McKee KK, Feighner SD, Sirinathsinghji DJ, et al. Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res Mol Brain Res (1997) 48:23-9. doi:10.1016/S0169-328X(97)00071-5
    • (1997) Brain Res Mol Brain Res , vol.48 , pp. 23-29
    • Guan, X.M.1    Yu, H.2    Palyha, O.C.3    McKee, K.K.4    Feighner, S.D.5    Sirinathsinghji, D.J.6
  • 38
    • 29044434688 scopus 로고    scopus 로고
    • Expression of ghrelin receptor mRNA in the rat and the mouse brain
    • doi:10.1002/cne.20823
    • Zigman JM, Jones JE, Lee CE, Saper CB, Elmquist JK. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J Comp Neurol (2006) 494:528-48. doi:10.1002/cne.20823
    • (2006) J Comp Neurol , vol.494 , pp. 528-548
    • Zigman, J.M.1    Jones, J.E.2    Lee, C.E.3    Saper, C.B.4    Elmquist, J.K.5
  • 39
    • 71749120339 scopus 로고    scopus 로고
    • Sequence, genomic organization and expression of two channel catfish, Ictalurus punctatus, ghrelin receptors
    • doi:10.1016/j.cbpa.2009.07.027
    • Small BC, Quiniou SM, Kaiya H. Sequence, genomic organization and expression of two channel catfish, Ictalurus punctatus, ghrelin receptors. Comp Biochem Physiol A Mol Integr Physiol (2009) 154:451-64. doi:10.1016/j.cbpa.2009.07.027
    • (2009) Comp Biochem Physiol A Mol Integr Physiol , vol.154 , pp. 451-464
    • Small, B.C.1    Quiniou, S.M.2    Kaiya, H.3
  • 40
    • 9944264980 scopus 로고    scopus 로고
    • Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks
    • doi:10.1016/j.regpep.2004.09.003
    • Saito E-S, Kaiya H, Tachibana T, Tomonaga S, Denbow DM, Kangawa K, et al. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regul Pept (2005) 125:201-8. doi:10.1016/j.regpep.2004.09.003
    • (2005) Regul Pept , vol.125 , pp. 201-208
    • Saito, E.-S.1    Kaiya, H.2    Tachibana, T.3    Tomonaga, S.4    Denbow, D.M.5    Kangawa, K.6
  • 41
    • 30344437267 scopus 로고    scopus 로고
    • Characterization of turkey and chicken ghrelin genes, and regulation of ghrelin and ghrelin receptor mRNA levels in broiler chickens
    • doi:10.1016/j.ygcen.2005.09.013
    • Richards MP, Poch SM, McMurtry JP. Characterization of turkey and chicken ghrelin genes, and regulation of ghrelin and ghrelin receptor mRNA levels in broiler chickens. Gen Comp Endocrinol (2006) 145:298-310. doi:10.1016/j.ygcen.2005.09.013
    • (2006) Gen Comp Endocrinol , vol.145 , pp. 298-310
    • Richards, M.P.1    Poch, S.M.2    McMurtry, J.P.3
  • 42
    • 42649125280 scopus 로고    scopus 로고
    • Primary structure, tissue distribution, and biological activity of chicken motilin receptor
    • doi:10.1016/j.ygcen.2008.03.007
    • Yamamoto I, Kaiya H, Tsutsui C, Sakai T, Tsukada A, Miyazato M, et al. Primary structure, tissue distribution, and biological activity of chicken motilin receptor. Gen Comp Endocrinol (2008) 156:509-14. doi:10.1016/j.ygcen.2008.03.007
    • (2008) Gen Comp Endocrinol , vol.156 , pp. 509-514
    • Yamamoto, I.1    Kaiya, H.2    Tsutsui, C.3    Sakai, T.4    Tsukada, A.5    Miyazato, M.6
  • 43
    • 38149038847 scopus 로고    scopus 로고
    • Predominant expression of growth hormone secretagogue receptor in the caudal lobe of chicken pituitary and parallel developmental increase in expression of pituitary GH and proventriculus ghrelin mRNA
    • doi:10.1111/j.1740-0929.2007.00506.x
    • Yamamoto I, Yoshimura Y, Tsukada A, Kansaku N, Tsushima N, Tanaka M. Predominant expression of growth hormone secretagogue receptor in the caudal lobe of chicken pituitary and parallel developmental increase in expression of pituitary GH and proventriculus ghrelin mRNA. NULL (2008) 79:116-21. doi:10.1111/j.1740-0929.2007.00506.x
    • (2008) , vol.79 , pp. 116-121
    • Yamamoto, I.1    Yoshimura, Y.2    Tsukada, A.3    Kansaku, N.4    Tsushima, N.5    Tanaka, M.6
  • 44
    • 76749085265 scopus 로고    scopus 로고
    • Molecular characterization of the ghrelin and ghrelin receptor genes and effects on fat deposition in chicken and duck
    • doi:10.1155/2009/567120
    • Nie Q, Fang M, Xie L, Peng X, Xu H, Luo C, et al. Molecular characterization of the ghrelin and ghrelin receptor genes and effects on fat deposition in chicken and duck. J Biomed Biotechnol (2009) 2009:567120. doi:10.1155/2009/567120
    • (2009) J Biomed Biotechnol , vol.2009 , pp. 567120
    • Nie, Q.1    Fang, M.2    Xie, L.3    Peng, X.4    Xu, H.5    Luo, C.6
  • 45
    • 56849107053 scopus 로고    scopus 로고
    • Molecular cloning and mRNA expression analysis of two GH secretagogue receptor transcripts in orange-spotted grouper (Epinephelus coioides)
    • doi:10.1677/JOE-08-0325
    • Chen T, Tang Z, Yan A, Li W, Lin H. Molecular cloning and mRNA expression analysis of two GH secretagogue receptor transcripts in orange-spotted grouper (Epinephelus coioides). J Endocrinol (2008) 199:253-65. doi:10.1677/JOE-08-0325
    • (2008) J Endocrinol , vol.199 , pp. 253-265
    • Chen, T.1    Tang, Z.2    Yan, A.3    Li, W.4    Lin, H.5
  • 46
    • 77950064307 scopus 로고    scopus 로고
    • Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain
    • doi:10.1016/j.cbpa.2010.01.019
    • Cruz SA, Tseng YC, Kaiya H, Hwang PP. Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain. Comp Biochem Physiol A Mol Integr Physiol (2010) 156:190-200. doi:10.1016/j.cbpa.2010.01.019
    • (2010) Comp Biochem Physiol A Mol Integr Physiol , vol.156 , pp. 190-200
    • Cruz, S.A.1    Tseng, Y.C.2    Kaiya, H.3    Hwang, P.P.4
  • 47
    • 33646374924 scopus 로고    scopus 로고
    • Ghrelin stimulates phagocytosis and superoxide production in fish leucocytes
    • doi:10.1677/joe.1.06187
    • Yada T, Kaiya H, Mutoh K, Azuma T, Hyodo S, Kangawa K. Ghrelin stimulates phagocytosis and superoxide production in fish leucocytes. J Endocrinol (2006) 189:57-65. doi:10.1677/joe.1.06187
    • (2006) J Endocrinol , vol.189 , pp. 57-65
    • Yada, T.1    Kaiya, H.2    Mutoh, K.3    Azuma, T.4    Hyodo, S.5    Kangawa, K.6
  • 48
    • 0042200265 scopus 로고    scopus 로고
    • Changes in ghrelin and ghrelin receptor expression according to feeding status
    • doi:10.1097/00001756-200307180-00006
    • Kim MS, Yoon CY, Park KH, Shin CS, Park KS, Kim SY, et al. Changes in ghrelin and ghrelin receptor expression according to feeding status. Neuroreport (2003) 4:1317-20. doi:10.1097/00001756-200307180-00006
    • (2003) Neuroreport , vol.4 , pp. 1317-1320
    • Kim, M.S.1    Yoon, C.Y.2    Park, K.H.3    Shin, C.S.4    Park, K.S.5    Kim, S.Y.6
  • 49
    • 4644249772 scopus 로고    scopus 로고
    • Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin
    • doi:10.2337/diabetes.53.10.2552
    • Nogueiras R, Tovar S, Mitchell SE, Rayner DV, Archer ZA, Dieguez C, et al. Regulation of growth hormone secretagogue receptor gene expression in the arcuate nuclei of the rat by leptin and ghrelin. Diabetes (2004) 53:2552-8. doi:10.2337/diabetes.53.10.2552
    • (2004) Diabetes , vol.53 , pp. 2552-2558
    • Nogueiras, R.1    Tovar, S.2    Mitchell, S.E.3    Rayner, D.V.4    Archer, Z.A.5    Dieguez, C.6
  • 51
    • 0242432330 scopus 로고    scopus 로고
    • Developmental, stage-specific, and hormonally regulated expression of growth hormone secretagogue receptor messenger RNA in rat testis
    • doi:10.1095/biolreprod.102.008862
    • Barreiro ML, Suominen JS, Gaytán F, Pinilla L, Chopin LK, Casanueva FF, et al. Developmental, stage-specific, and hormonally regulated expression of growth hormone secretagogue receptor messenger RNA in rat testis. Biol Reprod (2003) 68:1631-40. doi:10.1095/biolreprod.102.008862
    • (2003) Biol Reprod , vol.68 , pp. 1631-1640
    • Barreiro, M.L.1    Suominen, J.S.2    Gaytán, F.3    Pinilla, L.4    Chopin, L.K.5    Casanueva, F.F.6
  • 52
    • 0033305064 scopus 로고    scopus 로고
    • Growth hormone (GH)-releasing hormone (GHRH) and the GH secretagogue (GHS), L692,585, differentially modulate rat pituitary GHS receptor and GHRH receptor messenger ribonucleic acid levels
    • doi:10.1210/en.140.8.3581
    • Kineman RD, Kamegai J, Frohman LA. Growth hormone (GH)-releasing hormone (GHRH) and the GH secretagogue (GHS), L692,585, differentially modulate rat pituitary GHS receptor and GHRH receptor messenger ribonucleic acid levels. Endocrinology (1999) 140:3581-6. doi:10.1210/en.140.8.3581
    • (1999) Endocrinology , vol.140 , pp. 3581-3586
    • Kineman, R.D.1    Kamegai, J.2    Frohman, L.A.3
  • 53
    • 0035101104 scopus 로고    scopus 로고
    • Thyroid hormones regulate pituitary growth hormone secretagogue receptor gene expression
    • doi:10.1046/j.1365-2826.2001.00623.x
    • Kamegai J, Tamura H, Ishii S, Sugihara H, Wakabayashi I. Thyroid hormones regulate pituitary growth hormone secretagogue receptor gene expression. J Neuroendocrinol (2001) 13:275-8. doi:10.1046/j.1365-2826.2001.00623.x
    • (2001) J Neuroendocrinol , vol.13 , pp. 275-278
    • Kamegai, J.1    Tamura, H.2    Ishii, S.3    Sugihara, H.4    Wakabayashi, I.5
  • 54
    • 0034121372 scopus 로고    scopus 로고
    • Glucocorticoids regulate pituitary growth hormone secretagogue receptor gene expression
    • doi:10.1046/j.1365-2826.2000.00446.x
    • Tamura H, Kamegai J, Sugihara H, Kineman RD, Frohman LA, Wakabayashi I. Glucocorticoids regulate pituitary growth hormone secretagogue receptor gene expression. J Neuroendocrinol (2000) 12:481-5. doi:10.1046/j.1365-2826.2000.00446.x
    • (2000) J Neuroendocrinol , vol.12 , pp. 481-485
    • Tamura, H.1    Kamegai, J.2    Sugihara, H.3    Kineman, R.D.4    Frohman, L.A.5    Wakabayashi, I.6
  • 55
    • 0034109729 scopus 로고    scopus 로고
    • Glucocorticoid regulation of growth hormone (GH) secretagogue-induced growth responses and GH secretagogue receptor expression in the rat
    • doi:10.1054/ghir.1999.0138
    • Thomas GB, Bennett PA, Carmignac DF, Robinson IC. Glucocorticoid regulation of growth hormone (GH) secretagogue-induced growth responses and GH secretagogue receptor expression in the rat. Growth Horm IGF Res (2000) 10:45-52. doi:10.1054/ghir.1999.0138
    • (2000) Growth Horm IGF Res , vol.10 , pp. 45-52
    • Thomas, G.B.1    Bennett, P.A.2    Carmignac, D.F.3    Robinson, I.C.4
  • 56
    • 0030732108 scopus 로고    scopus 로고
    • Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat
    • doi:10.1210/en.138.11.4552
    • Bennett PA, Thomas GB, Howard AD, Feighner SD, van der Ploeg LH, Smith RG, et al. Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat. Endocrinology (1997) 138:4552-7. doi:10.1210/en.138.11.4552
    • (1997) Endocrinology , vol.138 , pp. 4552-4557
    • Bennett, P.A.1    Thomas, G.B.2    Howard, A.D.3    Feighner, S.D.4    van der Ploeg, L.H.5    Smith, R.G.6
  • 57
    • 0031761785 scopus 로고    scopus 로고
    • Growth hormone-dependent regulation of pituitary GH secretagogue receptor (GHS-R) mRNA levels in the spontaneous dwarf rat
    • doi:10.1159/000054379
    • Kamegai J, Wakabayashi I, Miyamoto K, Unterman TG, Kineman RD, Frohman LA. Growth hormone-dependent regulation of pituitary GH secretagogue receptor (GHS-R) mRNA levels in the spontaneous dwarf rat. Neuroendocrinology (1998) 68:312-8. doi:10.1159/000054379
    • (1998) Neuroendocrinology , vol.68 , pp. 312-318
    • Kamegai, J.1    Wakabayashi, I.2    Miyamoto, K.3    Unterman, T.G.4    Kineman, R.D.5    Frohman, L.A.6
  • 58
    • 0034455305 scopus 로고    scopus 로고
    • High plasma growth hormone (GH) levels inhibit expression of GH secretagogue receptor messenger ribonucleic acid levels in the rat pituitary
    • doi:10.1210/en.141.6.2084
    • Nass R, Gilrain J, Anderson S, Gaylinn B, Dalkin A, Day R, et al. High plasma growth hormone (GH) levels inhibit expression of GH secretagogue receptor messenger ribonucleic acid levels in the rat pituitary. Endocrinology (2000) 141:2084-9. doi:10.1210/en.141.6.2084
    • (2000) Endocrinology , vol.141 , pp. 2084-2089
    • Nass, R.1    Gilrain, J.2    Anderson, S.3    Gaylinn, B.4    Dalkin, A.5    Day, R.6
  • 59
    • 13144281741 scopus 로고    scopus 로고
    • Insulin-like growth factor-I down-regulates ghrelin receptor (growth hormone secretagogue receptor) expression in the rat pituitary
    • doi:10.1016/j.regpep.2004.12.001
    • Kamegai J, Tamura H, Shimizu T, Ishii S, Sugihara H, Oikawa S. Insulin-like growth factor-I down-regulates ghrelin receptor (growth hormone secretagogue receptor) expression in the rat pituitary. Regul Pept (2005) 127:203-6. doi:10.1016/j.regpep.2004.12.001
    • (2005) Regul Pept , vol.127 , pp. 203-206
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Oikawa, S.6
  • 60
    • 56649105264 scopus 로고    scopus 로고
    • Absence of effects of short-term fasting on plasma ghrelin and brain expression of ghrelin receptors in the tilapia, Oreochromis mossambicus
    • doi:10.2108/zsj.25.821
    • Riley LG, Fox BK, Breves JP, Kaiya H, Dorough CP, Hirano T, et al. Absence of effects of short-term fasting on plasma ghrelin and brain expression of ghrelin receptors in the tilapia, Oreochromis mossambicus. Zool Sci (2008) 25:821-7. doi:10.2108/zsj.25.821
    • (2008) Zool Sci , vol.25 , pp. 821-827
    • Riley, L.G.1    Fox, B.K.2    Breves, J.P.3    Kaiya, H.4    Dorough, C.P.5    Hirano, T.6
  • 61
    • 63449132308 scopus 로고    scopus 로고
    • Pre- and postprandial effects on ghrelin signaling in the brain and on the GH/IGF-I axis in the Mozambique tilapia (Oreochromis mossambicus)
    • doi:10.1016/j.ygcen.2009.02.008
    • Peddu SC, Breves JP, Kaiya H, Gordon GE, Riley LG Jr. Pre- and postprandial effects on ghrelin signaling in the brain and on the GH/IGF-I axis in the Mozambique tilapia (Oreochromis mossambicus). Gen Comp Endocrinol (2009) 161:412-8. doi:10.1016/j.ygcen.2009.02.008
    • (2009) Gen Comp Endocrinol , vol.161 , pp. 412-418
    • Peddu, S.C.1    Breves, J.P.2    Kaiya, H.3    Gordon, G.E.4    Riley, L.G.Jr.5
  • 63
    • 18244391222 scopus 로고    scopus 로고
    • Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
    • doi:10.1210/jc.87.1.240
    • Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab (2002) 87:240-4. doi:10.1210/jc.87.1.240
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 240-244
    • Shiiya, T.1    Nakazato, M.2    Mizuta, M.3    Date, Y.4    Mondal, M.S.5    Tanaka, M.6
  • 64
    • 1542373585 scopus 로고    scopus 로고
    • Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responses to central and peripheral injections
    • doi:10.1159/000076634
    • Unniappan S, Canosa LF, Peter RE. Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responses to central and peripheral injections. Neuroendocrinology (2004) 79:100-8. doi:10.1159/000076634
    • (2004) Neuroendocrinology , vol.79 , pp. 100-108
    • Unniappan, S.1    Canosa, L.F.2    Peter, R.E.3
  • 65
    • 85027922918 scopus 로고    scopus 로고
    • Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon
    • doi:10.1007/s10695-010-9434-3
    • Hevrøy EM, Azpeleta C, Shimizu M, Lanzén A, Kaiya H, Espe M, et al. Effects of short-term starvation on ghrelin, GH-IGF system, and IGF-binding proteins in Atlantic salmon. Fish Physiol Biochem (2011) 37:217-32. doi:10.1007/s10695-010-9434-3
    • (2011) Fish Physiol Biochem , vol.37 , pp. 217-232
    • Hevrøy, E.M.1    Azpeleta, C.2    Shimizu, M.3    Lanzén, A.4    Kaiya, H.5    Espe, M.6
  • 66
    • 79959935579 scopus 로고    scopus 로고
    • Central effects of ghrelin, a unique peptide, on appetite and fluid/water drinking behavior
    • doi:10.2174/138920311795906727
    • Hashimoto H, Ueta Y. Central effects of ghrelin, a unique peptide, on appetite and fluid/water drinking behavior. Curr Protein Pept Sci (2011) 12:280-7. doi:10.2174/138920311795906727
    • (2011) Curr Protein Pept Sci , vol.12 , pp. 280-287
    • Hashimoto, H.1    Ueta, Y.2
  • 67
    • 33746902373 scopus 로고    scopus 로고
    • Central ghrelin acts as an anti-dipsogenic peptide in chicks
    • doi:10.1016/j.neulet.2006.07.019
    • Tachibana T, Kaiya H, Denbow DM, Kangawa K, Furuse M. Central ghrelin acts as an anti-dipsogenic peptide in chicks. Neurosci Lett (2006) 405:241-5. doi:10.1016/j.neulet.2006.07.019
    • (2006) Neurosci Lett , vol.405 , pp. 241-245
    • Tachibana, T.1    Kaiya, H.2    Denbow, D.M.3    Kangawa, K.4    Furuse, M.5
  • 68
    • 3342962418 scopus 로고    scopus 로고
    • Isolation and characterization of the 5'-flanking region of the growth hormone secretagogue receptor gene from black seabream Acanthopagrus schlegeli
    • doi:10.1016/j.mce.2004.06.005
    • Yeung CM, Chan CB, Cheng CH. Isolation and characterization of the 5'-flanking region of the growth hormone secretagogue receptor gene from black seabream Acanthopagrus schlegeli. Mol Cell Endocrinol (2004) 223:5-15. doi:10.1016/j.mce.2004.06.005
    • (2004) Mol Cell Endocrinol , vol.223 , pp. 5-15
    • Yeung, C.M.1    Chan, C.B.2    Cheng, C.H.3
  • 69
    • 14044266920 scopus 로고    scopus 로고
    • Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice
    • doi:10.1128/MCB.25.5.1942-1948.2005
    • Wettschureck N, Moers A, Wallenwein B, Parlow AF, Maser-Gluth C, Offermanns S. Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice. Mol Cell Biol (2005) 25:1942-8. doi:10.1128/MCB.25.5.1942-1948.2005
    • (2005) Mol Cell Biol , vol.25 , pp. 1942-1948
    • Wettschureck, N.1    Moers, A.2    Wallenwein, B.3    Parlow, A.F.4    Maser-Gluth, C.5    Offermanns, S.6
  • 70
    • 0025790152 scopus 로고
    • Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-D-Phe-Lys-NH2-induced growth hormone release from rat primary pituitary cells
    • doi:10.1210/endo-129-6-3337
    • Cheng K, Chan WW, Butler B, Barreto A Jr., Smith RG. Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-D-Phe-Lys-NH2-induced growth hormone release from rat primary pituitary cells. Endocrinology (1991) 129:3337-42. doi:10.1210/endo-129-6-3337
    • (1991) Endocrinology , vol.129 , pp. 3337-3342
    • Cheng, K.1    Chan, W.W.2    Butler, B.3    Barreto Jr., A.4    Smith, R.G.5
  • 71
    • 0028037649 scopus 로고
    • Growth hormone-releasing hexapeptide elevates intracellular calcium in rat somatotropes by two mechanisms
    • doi:10.1210/en.135.3.1100
    • Herrington J, Hille B. Growth hormone-releasing hexapeptide elevates intracellular calcium in rat somatotropes by two mechanisms. Endocrinology (1994) 135:1100-8. doi:10.1210/en.135.3.1100
    • (1994) Endocrinology , vol.135 , pp. 1100-1108
    • Herrington, J.1    Hille, B.2
  • 72
    • 0028923415 scopus 로고
    • Growth hormone releasing peptide (GHRP-6) stimulates phosphatidylinositol (PI) turnover in human pituitary somatotroph cells
    • doi:10.1677/jme.0.0140135
    • Lei T, Buchfelder M, Fahlbusch R, Adams EF. Growth hormone releasing peptide (GHRP-6) stimulates phosphatidylinositol (PI) turnover in human pituitary somatotroph cells. J Mol Endocrinol (1995) 14:135-8. doi:10.1677/jme.0.0140135
    • (1995) J Mol Endocrinol , vol.14 , pp. 135-138
    • Lei, T.1    Buchfelder, M.2    Fahlbusch, R.3    Adams, E.F.4
  • 73
    • 0029983654 scopus 로고    scopus 로고
    • GHRP6-stimulated hormone secretion in somatotrophs: involvement of intracellular and extracellular calcium sources
    • doi:10.1046/j.1365-2826.1996.04608.x
    • Bresson-Bépoldin L, Dufy-Barbe L. GHRP6-stimulated hormone secretion in somatotrophs: involvement of intracellular and extracellular calcium sources. J Neuroendocrinol (1996) 8:309-14. doi:10.1046/j.1365-2826.1996.04608.x
    • (1996) J Neuroendocrinol , vol.8 , pp. 309-314
    • Bresson-Bépoldin, L.1    Dufy-Barbe, L.2
  • 74
    • 0031716255 scopus 로고    scopus 로고
    • Growth hormone-releasing hexapeptide (GHRP-6) increases intracellular calcium concentrations in cultured cells from human pituitary adenomas of different types
    • doi:10.1530/eje.0.1390343
    • Lania A, Ballaré E, Corbetta S, Filopanti M, Persani L, Spada A. Growth hormone-releasing hexapeptide (GHRP-6) increases intracellular calcium concentrations in cultured cells from human pituitary adenomas of different types. Eur J Endocrinol (1998) 139:343-8. doi:10.1530/eje.0.1390343
    • (1998) Eur J Endocrinol , vol.139 , pp. 343-348
    • Lania, A.1    Ballaré, E.2    Corbetta, S.3    Filopanti, M.4    Persani, L.5    Spada, A.6
  • 75
    • 24344479915 scopus 로고    scopus 로고
    • Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling
    • doi:10.1210/me.2005-0059
    • Holst B, Brandt E, Bach A, Heding A, Schwartz TW. Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. Mol Endocrinol (2005) 19:2400-11. doi:10.1210/me.2005-0059
    • (2005) Mol Endocrinol , vol.19 , pp. 2400-2411
    • Holst, B.1    Brandt, E.2    Bach, A.3    Heding, A.4    Schwartz, T.W.5
  • 76
    • 33847716287 scopus 로고    scopus 로고
    • Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1/2 activity
    • Chu KM, Chow KB, Leung PK, Lau PN, Chan CB, Cheng CH, et al. Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1/2 activity. Int J Biochem Cell Biol (2007) 39:752-64.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 752-764
    • Chu, K.M.1    Chow, K.B.2    Leung, P.K.3    Lau, P.N.4    Chan, C.B.5    Cheng, C.H.6
  • 77
    • 7544230057 scopus 로고    scopus 로고
    • Signal transduction mechanism of the seabream growth hormone secretagogue receptor
    • doi:10.1016/j.febslet.2004.08.088
    • Chan CB, Leung PK, Wise H, Cheng CH. Signal transduction mechanism of the seabream growth hormone secretagogue receptor. FEBS Lett (2004) 577:147-53. doi:10.1016/j.febslet.2004.08.088
    • (2004) FEBS Lett , vol.577 , pp. 147-153
    • Chan, C.B.1    Leung, P.K.2    Wise, H.3    Cheng, C.H.4
  • 78
    • 79952489916 scopus 로고    scopus 로고
    • Central injection of des-acyl chicken ghrelin does not affect food intake in chicks
    • doi:10.1016/j.ygcen
    • Tachibana T, Tanaka M, Kaiya H. Central injection of des-acyl chicken ghrelin does not affect food intake in chicks. Gen Comp Endocrinol (2011) 171:183-8. doi:10.1016/j.ygcen
    • (2011) Gen Comp Endocrinol , vol.171 , pp. 183-188
    • Tachibana, T.1    Tanaka, M.2    Kaiya, H.3
  • 79
    • 58149144575 scopus 로고    scopus 로고
    • Ghrelin-induced growth hormone release from goldfish pituitary cells involves voltage-sensitive calcium channels
    • doi:10.1016/j.ygcen.2008.11.006
    • Grey CL, Chang JP. Ghrelin-induced growth hormone release from goldfish pituitary cells involves voltage-sensitive calcium channels. Gen Comp Endocrinol (2009) 160:148-57. doi:10.1016/j.ygcen.2008.11.006
    • (2009) Gen Comp Endocrinol , vol.160 , pp. 148-157
    • Grey, C.L.1    Chang, J.P.2
  • 81
    • 15444361604 scopus 로고    scopus 로고
    • Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues
    • Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, et al. Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues. Mol Endocrinol (1998) 2:137-45.
    • (1998) Mol Endocrinol , vol.2 , pp. 137-145
    • Feighner, S.D.1    Howard, A.D.2    Prendergast, K.3    Palyha, O.C.4    Hreniuk, D.L.5    Nargund, R.6
  • 82
    • 0242330291 scopus 로고    scopus 로고
    • High constitutive signaling of the ghrelin receptor - identification of a potent inverse agonist
    • doi:10.1210/me.2003-0069
    • Holst B, Cygankiewicz A, Jensen TH, Ankersen M, Schwartz TW. High constitutive signaling of the ghrelin receptor - identification of a potent inverse agonist. Mol Endocrinol (2003) 217:2201-10. doi:10.1210/me.2003-0069
    • (2003) Mol Endocrinol , vol.217 , pp. 2201-2210
    • Holst, B.1    Cygankiewicz, A.2    Jensen, T.H.3    Ankersen, M.4    Schwartz, T.W.5
  • 83
    • 11144225093 scopus 로고    scopus 로고
    • Common structural basis for constitutive activity of the ghrelin receptor family
    • doi:10.1074/jbc.M407676200
    • Holst B, Holliday ND, Bach A, Elling CE, Cox HM, Schwartz TW. Common structural basis for constitutive activity of the ghrelin receptor family. J Biol Chem (2004) 279:53806-17. doi:10.1074/jbc.M407676200
    • (2004) J Biol Chem , vol.279 , pp. 53806-53817
    • Holst, B.1    Holliday, N.D.2    Bach, A.3    Elling, C.E.4    Cox, H.M.5    Schwartz, T.W.6
  • 84
    • 34548093246 scopus 로고    scopus 로고
    • Four missense mutations in the ghrelin receptor result in distinct pharmacological abnormalities
    • doi:10.1124/jpet.107.123141
    • Liu G, Fortin JP, Beinborn M, Kopin AS. Four missense mutations in the ghrelin receptor result in distinct pharmacological abnormalities. J Pharmacol Exp Ther (2007) 322:1036-43. doi:10.1124/jpet.107.123141
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 1036-1043
    • Liu, G.1    Fortin, J.P.2    Beinborn, M.3    Kopin, A.S.4
  • 85
    • 80655149447 scopus 로고    scopus 로고
    • Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors
    • doi:10.1074/jbc.M111.287607
    • Rediger A, Piechowski CL, Yi CX, Tarnow P, Strotmann R, Grüters A, et al. Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors. J Biol Chem (2011) 86:39623-31. doi:10.1074/jbc.M111.287607
    • (2011) J Biol Chem , vol.86 , pp. 39623-39631
    • Rediger, A.1    Piechowski, C.L.2    Yi, C.X.3    Tarnow, P.4    Strotmann, R.5    Grüters, A.6
  • 86
    • 33947301456 scopus 로고    scopus 로고
    • The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor
    • doi:10.1016/j.cellsig.2006.11.011
    • Leung PK, Chow KB, Lau PN, Chu KM, Chan CB, Cheng CH, et al. The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Cell Signal (2007) 19:1011-22. doi:10.1016/j.cellsig.2006.11.011
    • (2007) Cell Signal , vol.19 , pp. 1011-1022
    • Leung, P.K.1    Chow, K.B.2    Lau, P.N.3    Chu, K.M.4    Chan, C.B.5    Cheng, C.H.6
  • 87
    • 33344479006 scopus 로고    scopus 로고
    • Ghrelin controls hippocampal spine synapse density and memory performance
    • doi:10.1038/nn1656
    • Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, et al. Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci (2006) 9:381-8. doi:10.1038/nn1656
    • (2006) Nat Neurosci , vol.9 , pp. 381-388
    • Diano, S.1    Farr, S.A.2    Benoit, S.C.3    McNay, E.C.4    da Silva, I.5    Horvath, B.6
  • 88
    • 77953916316 scopus 로고    scopus 로고
    • Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus
    • doi:10.1016/j.physbeh.2010.04.026
    • Carlini VP, Perez MF, Salde E, Schiöth HB, Ramirez OA, de Barioglio SR. Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus. Physiol Behav (2010) 101:117-23. doi:10.1016/j.physbeh.2010.04.026
    • (2010) Physiol Behav , vol.101 , pp. 117-123
    • Carlini, V.P.1    Perez, M.F.2    Salde, E.3    Schiöth, H.B.4    Ramirez, O.A.5    de Barioglio, S.R.6
  • 89
    • 84863962816 scopus 로고    scopus 로고
    • Ghrelin's second life: from appetite stimulator to glucose regulator
    • doi:10.3748/wjg.v18.i25.3183
    • Verhulst PJ, Depoortere I. Ghrelin's second life: from appetite stimulator to glucose regulator. World J Gastroenterol (2012) 18:3183-95. doi:10.3748/wjg.v18.i25.3183
    • (2012) World J Gastroenterol , vol.18 , pp. 3183-3195
    • Verhulst, P.J.1    Depoortere, I.2
  • 90
    • 84859424263 scopus 로고    scopus 로고
    • GHRP-6 mimics ghrelin-induced stimulation of food intake and suppression of locomotor activity in goldfish
    • doi:10.1016/j.peptides.2012.01.025
    • Yahashi S, Kang KS, Kaiya H, Matsuda K. GHRP-6 mimics ghrelin-induced stimulation of food intake and suppression of locomotor activity in goldfish. Peptides (2012) 34:324-8. doi:10.1016/j.peptides.2012.01.025
    • (2012) Peptides , vol.34 , pp. 324-328
    • Yahashi, S.1    Kang, K.S.2    Kaiya, H.3    Matsuda, K.4
  • 91
    • 2442697904 scopus 로고    scopus 로고
    • In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish
    • doi:10.1152/ajpregu.00669.2003
    • Unniappan S, Peter RE. In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish. Am J Physiol Regul Integr Comp Physiol (2004) 286:R1093-101. doi:10.1152/ajpregu.00669.2003
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Unniappan, S.1    Peter, R.E.2
  • 92
    • 84864821852 scopus 로고    scopus 로고
    • Ghrelin does not affect gastrointestinal contractility in rainbow trout and goldfish in vitro
    • doi:10.1016/j.ygcen
    • Kitazawa T, Itoh K, Yaosaka N, Maruyama K, Matsuda K, Teraoka H, et al. Ghrelin does not affect gastrointestinal contractility in rainbow trout and goldfish in vitro. Gen Comp Endocrinol (2012) 178:539-45. doi:10.1016/j.ygcen
    • (2012) Gen Comp Endocrinol , vol.178 , pp. 539-545
    • Kitazawa, T.1    Itoh, K.2    Yaosaka, N.3    Maruyama, K.4    Matsuda, K.5    Teraoka, H.6
  • 93
    • 36248960540 scopus 로고    scopus 로고
    • Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin
    • doi:10.1016/j.ygcen.2007.05.016
    • Olsson C, Holbrook JD, Bompadre G, Jönsson E, Hoyle CH, Sanger GJ, et al. Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin. Gen Comp Endocrinol (2008) 155:217-26. doi:10.1016/j.ygcen.2007.05.016
    • (2008) Gen Comp Endocrinol , vol.155 , pp. 217-226
    • Olsson, C.1    Holbrook, J.D.2    Bompadre, G.3    Jönsson, E.4    Hoyle, C.H.5    Sanger, G.J.6
  • 94
    • 80755132266 scopus 로고    scopus 로고
    • The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression
    • doi:10.1016/j.mce.2011.08.034
    • Chow KB, Sun J, Chu KM, Tai Cheung W, Cheng CH, Wise H. The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression. Mol Cell Endocrinol (2012) 348:247-54. doi:10.1016/j.mce.2011.08.034
    • (2012) Mol Cell Endocrinol , vol.348 , pp. 247-254
    • Chow, K.B.1    Sun, J.2    Chu, K.M.3    Tai Cheung, W.4    Cheng, C.H.5    Wise, H.6
  • 95
    • 33750323311 scopus 로고    scopus 로고
    • The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer
    • doi:10.1158/0008-5472.CAN-06-1349
    • Takahashi K, Furukawa C, Takano A, Ishikawa N, Kato T, Hayama S, et al. The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer. Cancer Res (2006) 66:9408-19. doi:10.1158/0008-5472.CAN-06-1349
    • (2006) Cancer Res , vol.66 , pp. 9408-9419
    • Takahashi, K.1    Furukawa, C.2    Takano, A.3    Ishikawa, N.4    Kato, T.5    Hayama, S.6
  • 98
    • 84869787270 scopus 로고    scopus 로고
    • Resolving the phylogeny of lizards and snakes (Squamata) with extensive sampling of genes and species
    • doi:10.1098/rsbl.2012.0703
    • Wiens JJ, Hutter CR, Mulcahy DG, Noonan BP, Townsend TM, Sites JW Jr., et al. Resolving the phylogeny of lizards and snakes (Squamata) with extensive sampling of genes and species. Biol Lett (2012) 8:1043-6. doi:10.1098/rsbl.2012.0703
    • (2012) Biol Lett , vol.8 , pp. 1043-1046
    • Wiens, J.J.1    Hutter, C.R.2    Mulcahy, D.G.3    Noonan, B.P.4    Townsend, T.M.5    Sites Jr., J.W.6
  • 100
    • 84884193208 scopus 로고    scopus 로고
    • Direct submission, database only
    • Yu HJ (2011, direct submission, database only).
    • (2011)
    • Yu, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.