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Bioorganic and Medicinal Chemistry

Volumn 18, Issue 15, 2010, Pages 5483-5488

The peptide hormone ghrelin binds to membrane-mimetics via its octanoyl chain and an adjacent phenylalanine

(4) Großauer, Jörg a Kosol, Simone a Schrank, Evelyne a Zangger, Klaus a

a UNIVERSITY OF GRAZ (Austria)

Author keywords

Ghrelin; hGHSR 1a; Membrane mimetic; NMR spectroscopy; Octanoylation; Paramagnetic relaxation enhancement

Indexed keywords

AROMATIC COMPOUND; DESOCTANOYL GHRELIN; GHRELIN; HORMONE DERIVATIVE; OCTANOL; PEPTIDE; PHENYLALANINE; PHOSPHORYLCHOLINE; UNCLASSIFIED DRUG; GHRELIN RECEPTOR; OCTANE; SERINE;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CHEMICAL MODIFICATION; CONTROLLED STUDY; HYDROPHOBICITY; MAGNETISM; MEMBRANE BINDING; MICELLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAMAGNETIC RELAXATION ENHANCEMENT; PROTEIN FUNCTION; STOICHIOMETRY; ULTRAFILTRATION; CHEMISTRY; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

CELL MEMBRANE; GHRELIN; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OCTANES; PHENYLALANINE; RECEPTORS, GHRELIN; SERINE;

EID: 77955417391 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2010.06.062 Document Type: Article

Times cited : (25)

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