Molecular cloning of growth hormone secretagogue-receptor and effect of quail ghrelin on gastrointestinal motility in Japanese quail

Regulatory Peptides

Volumn 158, Issue 1-3, 2009, Pages 132-142

  Kitazawa, Takio ^a   Maeda, Yoshimi ^a   Kaiya, Hiroyuki ^b  

^a RAKUNO GAKUEN UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Chicken; Gastrointestinal tract; Ghrelin; Growth hormone secretagogue receptor; Japanese quail; Motilin

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; GASTROINTESTINAL POLYPEPTIDE; GHRELIN; GHRELIN RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR; MESSENGER RNA; MOTILIN; RECEPTOR SUBTYPE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVIAN STOMACH; CEREBELLUM; CHICKEN; COLON; CONTROLLED STUDY; CROP; ESOPHAGUS; GASTROINTESTINAL MOTILITY; GENETIC HETEROGENEITY; HORMONE RESPONSE; INTESTINE; INTESTINE CONTRACTION; JAPANESE; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUAIL; REGULATORY MECHANISM; SMALL INTESTINE; SPECIES DIFFERENCE; UPPER GASTROINTESTINAL TRACT;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHICKENS; CLONING, MOLECULAR; COTURNIX; DNA PRIMERS; DNA, COMPLEMENTARY; GASTROINTESTINAL MOTILITY; GHRELIN; MALE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, GHRELIN; SEQUENCE HOMOLOGY, AMINO ACID;

AVES; COTURNIX JAPONICA; PHASIANIDAE;

EID: 70349739079     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2009.07.005     Document Type: Article

References (34)

1. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
2. Kojima M., and Kangawa K. Ghrelin: structure and function. Physiol Rev 85 (2005) 495-522
3. Gnanapavan S., Kola B., Bustin S.A., Morris D.G., McGee P., Fairclough P., Bhattacharya S., Carpenter R., Grossman A.B., and Korbonits M. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab 87 (2002) 2988-2991
4. Papotti M., Ghe C., Cassoni P., Catapano F., Deghenghi R., Ghigo E., and Muccioli G. Growth hormone secretagogue binding sites in peripheral human tissues. J Clin Endocrinol Metab 85 (2000) 3803-3807
5. Davenport A.P., Bonner T.I., Foord S.M., Harmar A.J., Neubig R.R., Pin J.P., Spedding M., Kojima M., and Kangawa K. Intenational Union of Pharmacology LVI. Ghrelin receptor nomenclature, distribution, and function. Pharmacol Rev 57 (2005) 541-546
6. Kaiya H., Darras V.M., and Kangawa K. Ghrelin in birds; its structure, distribution and function. J Poult Sci 44 (2007) 1-18
7. Kaiya H., Miyazato M., Kangawa K., Peter R.E., and Unniappan S. Ghrelin: a multifunctional hormone in non-mammalian vertebrates. Comp Biochem Physiol A 149 (2008) 109-128
8. Kaiya H., Van Der Geyten S., Kojima M., Hosoda H., Kitajima Y., Matsumoto M., Geelissen S., Darras V.M., and Kangawa K. Chicken ghrelin: purification, cDNA cloning, and biological activity. Endocrinology 143 (2002) 3454-3463
9. Richards M.P., Poch S.M., and McMurtry J.P. Characterization of turkey and chicken ghrelin genes, and regulation of ghrelin and ghrelin receptor mRNA levels in broiler chickens. Gen Comp Endocrinol 145 (2006) 298-310
10. Yoshimura Y., Nagano K., Subedi K., and Kaiya K. Identification of immunoreactive ghrelin and its mRNA in the oviduct of laying Japanese quail, Coturnix japonica. J Poult Sci 42 (2005) 291-300
11. Geelissen S., Beck I.M., Darras V.M., Kühn E., and van der Geyten S. Distribution and regulation of chicken growth hormone secretagogue receptor isoforms. Gen Comp Endocrinol 134 (2003) 167-174
12. Tanaka M., Miyazaki T., Yamamoto I., Nakai N., Ohta Y., Tsushima N., Wakita M., and Shimada K. Molecular characterization of chicken growth hormone secretagogue receptor gene. Gen Comp Endocrinol 134 (2003) 198-202
13. Sirotkin A.V., Grossmann R., María-Peon M.T., Roa J., Tena-Sempere M., and Klein S. Novel expression and functional role of ghrelin in chicken ovary. Mol Cell Endocrinol 257-258 (2006) 15-25
14. Furuse M., Tachibana T., Ohgushi A., Ando R., Yoshimatsu T., and Denbow D.M. Intracerebroventricular injection of ghrelin and growth hormone releasing factor inhibits food intake in neonatal chicks. Neurosci Lett 301 (2001) 123-126
15. Saito E.S., Kaiya H., Takagi T., Yamasaki I., Denbow D.M., Kangawa K., and Furuse M. Chicken ghrelin and growth hormone-releasing peptide-2 inhibit food intake of neonatal chicks. Eur J Pharmacol 453 (2002) 75-79
16. Geelissen S.M., Swennen Q., Geyten S.V., Kühn E.R., Kaiya H., Kangawa K., Decuypere E., Buyse J., and Darras V.M. Peripheral ghrelin reduces food intake and respiratory quotient in chicken. Domest Anim Endocrinol 30 (2006) 108-116
17. Nakazato M., Murakami N., Date Y., Kojima M., Matsuo H., Kangawa K., and Matsukura S. A role for ghrelin in the central regulation of feeding. Nature 409 (2001) 194-198
18. Matsuda K., Miura T., Kaiya H., Maruyama K., Shimakura S., Uchiyama M., Kangawa K., and Shioda S. Regulation of food intake by acyl and des-acyl ghrelins in the goldfish. Peptides 27 (2006) 2321-2325
19. Shousha S., Nakahara K., Kojima M., Miyazato M., Hosoda H., Kangawa K., and Murakami N. Different effects of peripheral and central ghrelin on regulation of food intake in Japanese quail. Gen Comp Endocrinol 141 (2005) 178-183
20. Fujino K., Inui A., Asakawa A., Kihara N., Fujimura M., and Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol 550 (2003) 227-240
21. Kitazawa T., Kaiya H., and Taneike T. Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro. Peptides 28 (2007) 617-624
22. Asakawa A., Inui A., Kaga T., Yuzuriha H., Nagata T., Ueno N., Makino S., Fujimiya M., Niijima A., Masayuki A., Fujino M., and Kasuga M. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120 (2001) 337-345
23. Peeters T.L. Ghrelin: a new player in the control of gastrointestinal functions. Gut 54 (2005) 1638-1649
24. Yamamoto I., Kaiya H., Tsutsui C., Sakai T., Tsukada A., Miyazato M., and Tanaka M. Primary structure, tissue distribution, and biological activity of chicken motilin receptor. Gen Comp Endocrinol 156 (2008) 509-514
25. Peeters T.L., Aerssens J., De Smet B., Mitselos A., Thielemans L., Coulie B., and Depoortere I. The mouse is a natural knock-out for motilin and for the motilin receptor. Functionally they have been replaced by ghrelin. Neurogastroenterol Motil 16 (2004) 687
26. Aerssens J., Depoortere I., Thielemans L., Mitselos A., Coulie B., and Peeters T.L. The rat lacks functional genes for motilin and for the motilin receptor. Neurogastroenterol Motil 16 (2004) 841
27. Howard A.D., Feighner S.D., Cully D.F., Arena J.P., Liberator P.A., Rosenblum C.I., Hamelin M., Hreniuk D.L., Palyha O.C., Anderson J., Paress P.S., Diaz C., Chou M., Liu K.K., McKee K.K., Pong S.S., Chaung L.Y., Elbrecht A., Dashkevicz M., Heavens R., et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273 (1996) 974-977
28. Chen C.B., and Cheng C.H. Identification and functional characterization of two alternatively spliced growth hormone secretagogue receptor transcripts from the pituitary of black seabream, Acanthopagrus schlegeli. Mol Cell Endocrinol 214 (2004) 81-95
29. Chu K.M., Chow K.B., Leung P.K., Lau P.N., Chan C.B., Cheng C.H., and Wise H. Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1/2 activity. Int J Biochem Cell Biol 39 (2007) 752-764
30. Leung P.K., Chow K.B., Lau P.N., Chu K.M., Chan C.B., Cheng C.H., and Wise H. The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Cell Signal 19 (2007) 1011-1022
31. Takeshita E., Matsuura B., Dong M., Miller L.J., Matsui H., and Onji M. Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract. J Gastroenterol 41 (2006) 223-230
32. Dass N.B., Munonyara M., Bassil A.K., Hervieu G.J., Osbourne S., Corcoran S., Morgan M., and Sanger G.J. Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin. Neuroscience 120 (2003) 443-453
33. Rodriguez-Sinovas A., Jimenez M., De Clercq P., Peeters T.L., and Vergara P. Rhythmic oscillating complexes in gastrointestinal tract of chicken: a role for motilin. Am J Physiol 272 (1997) G916-G922
34. Wierup N., Bjorkqvist M., Wesrom B., Pierzynowski S., Sundler F., and Sjolund K. Ghrelin and motilin are cosecreted from a prominent endocrine cell population in the small intestine. J Clin Endocrinol Metab 92 (2007) 3573-3581