PEAR1 attenuates megakaryopoiesis via control of the PI3K/PTEN pathway

Blood

Volumn 121, Issue 6, 2013, Pages 5208-5217

  Kauskot, Alexandre ^a   Vandenbriele, Christophe ^a   Louwette, Sophie ^a   Gijsbers, Rik ^b,c   Tousseyn, Thomas ^b   Freson, Kathleen ^a   Verhamme, Peter ^a   Hoylaerts, Marc F ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; MEMBRANE PROTEIN; MORPHOLINO OLIGONUCLEOTIDE; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1; PROTEIN KINASE B; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; MESSENGER RNA; PEAR1 PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; BONE MATURATION; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONOGENIC ASSAY; COLONY FORMING UNIT; COLONY FORMING UNIT E; COLONY FORMING UNIT MK; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MEGAKARYOCYTE; MEGAKARYOPOIESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; THROMBOCYTOPOIESIS; WESTERN BLOTTING; ZEBRA FISH; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IN SITU HYBRIDIZATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THROMBOCYTE;

ANIMALS; BLOOD PLATELETS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; MEGAKARYOCYTES; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBOPOIESIS; ZEBRAFISH;

EID: 84884174033     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-462887     Document Type: Article

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