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Volumn 788, Issue , 2012, Pages 291-303

Megakaryopoiesis and thrombopoiesis: An update on cytokines and lineage surface markers

Author keywords

c Mpl; CD41; Cytokine; Hematopoietic stem cells; Megakaryocyte; Megakaryocyte progenitor; Megakaryopoiesis; Surface marker; Thrombopoiesis; Thrombopoietin

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE;

EID: 84555190120     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-307-3_20     Document Type: Article
Times cited : (38)

References (76)
  • 1
    • 33748650063 scopus 로고    scopus 로고
    • Biological characteristics of megakaryocytes: Specific lineage commitment and associated disorders
    • DOI 10.1016/j.biocel.2006.03.011, PII S1357272506001014
    • Sun, L., Hwang, W. Y., and Aw, S. E. (2006) Biological characteristics of megakaryocytes: specific lineage commitment and associated disorders. Int J Biochem Cell Biol 38 , 1821-6. (Pubitemid 44425242)
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , Issue.11 , pp. 1821-1826
    • Sun, L.1    Hwang, W.Y.K.2    Aw, S.E.3
  • 2
    • 34250727187 scopus 로고    scopus 로고
    • From hematopoietic stem cells to platelets
    • DOI 10.1111/j.1538-7836.2007.02472.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • Chang, Y., Bluteau, D., Debili, N., and Vainchenker, W. (2007) From hematopoietic stem cells to platelets. J Thromb Haemost 5 Suppl 1 , 318-27. (Pubitemid 46958849)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 318-327
    • Chang, Y.1    Bluteau, D.2    Debili, N.3    Vainchenker, W.4
  • 3
    • 68549085529 scopus 로고    scopus 로고
    • Establishment of a normal hematopoietic and leukemia stem cell hierarchy
    • Chao, M. P., Seita, J., and Weissman, I. L. (2008) Establishment of a normal hematopoietic and leukemia stem cell hierarchy. Cold Spring Harb Symp Quant Biol 73 , 439-49.
    • (2008) Cold Spring Harb Symp Quant Biol , vol.73 , pp. 439-49
    • Chao, M.P.1    Seita, J.2    Weissman, I.L.3
  • 4
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
    • DOI 10.1016/j.cell.2008.01.025, PII S0092867408001256
    • Orkin, S. H., and Zon, L. I. (2008) Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132 , 631-44. (Pubitemid 351260057)
    • (2008) Cell , vol.132 , Issue.4 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 8
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • DOI 10.1038/35004599
    • Akashi, K., Traver, D., Miyamoto, T., and Weissman, I. L. (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404 , 193-7. (Pubitemid 30154488)
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 10
    • 33746208874 scopus 로고    scopus 로고
    • + Multipotent Hematopoietic Progenitors
    • DOI 10.1016/j.cell.2006.06.037, PII S0092867406008580
    • Forsberg, E. C., Serwold, T., Kogan, S., Weissman, I. L., and Passegue, E. (2006) New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell 126 , 415-26. (Pubitemid 44092964)
    • (2006) Cell , vol.126 , Issue.2 , pp. 415-426
    • Forsberg, E.C.1    Serwold, T.2    Kogan, S.3    Weissman, I.L.4    Passegue, E.5
  • 11
    • 34848896359 scopus 로고    scopus 로고
    • Elucidation of the Phenotypic, Functional, and Molecular Topography of a Myeloerythroid Progenitor Cell Hierarchy
    • DOI 10.1016/j.stem.2007.07.005, PII S1934590907000719
    • Pronk, C. J., Rossi, D. J., Mansson, R., Attema, J. L., Norddahl, G. L., Chan, C. K., Sigvardsson, M., Weissman, I. L., and Bryder, D. (2007) Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 1 , 428-42. (Pubitemid 47506534)
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 428-442
    • Pronk, C.J.H.1    Rossi, D.J.2    Mansson, R.3    Attema, J.L.4    Norddahl, G.L.5    Chan, C.K.F.6    Sigvardsson, M.7    Weissman, I.L.8    Bryder, D.9
  • 14
    • 37049035381 scopus 로고    scopus 로고
    • Novel role for EKLF in megakaryocyte lineage commitment
    • DOI 10.1182/blood-2007-03-082065
    • Frontelo, P., Manwani, D., Galdass, M., Karsunky, H., Lohmann, F., Gallagher, P. G., and Bieker, J. J. (2007) Novel role for EKLF in megakaryocyte lineage commitment. Blood 110 , 3871-80. (Pubitemid 350248442)
    • (2007) Blood , vol.110 , Issue.12 , pp. 3871-3880
    • Frontelo, P.1    Manwani, D.2    Galdass, M.3    Karsunky, H.4    Lohmann, F.5    Gallagher, P.G.6    Bieker, J.J.7
  • 16
    • 7244258902 scopus 로고    scopus 로고
    • Human marrow megakaryocyte differentiation: Multiparameter correlative analysis identifies von Willebrand factor as a sensitive and distinctive marker for early (2N and 4N) megakaryocytes
    • DOI 10.1182/blood-2004-02-0769
    • Tomer, A. (2004) Human marrow megakaryocyte differentiation: multiparameter correlative analysis identifies von Willebrand factor as a sensitive and distinctive marker for early (2 N and 4 N) megakaryocytes. Blood 104 , 2722-7. (Pubitemid 39434953)
    • (2004) Blood , vol.104 , Issue.9 , pp. 2722-2727
    • Tomer, A.1
  • 17
    • 0037438975 scopus 로고    scopus 로고
    • Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo
    • DOI 10.1182/blood-2002-06-1699
    • Mikkola, H. K., Fujiwara, Y., Schlaeger, T. M., Traver, D., and Orkin, S. H. (2003) Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 101 , 508-16. (Pubitemid 36082842)
    • (2003) Blood , vol.101 , Issue.2 , pp. 508-516
    • Mikkola, H.K.A.1    Fujiwara, Y.2    Schlaeger, T.M.3    Traver, D.4    Orkin, S.H.5
  • 19
    • 15244352092 scopus 로고    scopus 로고
    • GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties
    • DOI 10.1016/j.exphem.2005.01.011
    • Berlanga, O., Emambokus, N., and Frampton, J. (2005) GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties. Exp Hematol 33 , 403-12. (Pubitemid 40387622)
    • (2005) Experimental Hematology , vol.33 , Issue.4 , pp. 403-412
    • Berlanga, O.1    Emambokus, N.2    Frampton, J.3
  • 21
    • 0028343099 scopus 로고
    • Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
    • Bartley, T. D., Bogenberger, J., Hunt, P., Li, Y. S., Lu, H. S., Martin, F., Chang, M. S., Samal, B., Nichol, J. L., Swift, S., and et al. (1994) Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77 , 1117-24.
    • (1994) Cell , vol.77 , pp. 1117-24
    • Bartley, T.D.1    Bogenberger, J.2    Hunt, P.3    Li, Y.S.4    Lu, H.S.5    Martin, F.6    Chang, M.S.7    Samal, B.8    Nichol, J.L.9    Swift, S.10
  • 27
    • 0027992924 scopus 로고
    • Molecular cloning and chromosomal localization of the human thrombopoietin gene
    • DOI 10.1016/0014-5793(94)01008-0
    • Sohma, Y., Akahori, H., Seki, N., Hori, T., Ogami, K., Kato, T., Shimada, Y., Kawamura, K., and Miyazaki, H. (1994) Molecular cloning and chromosomal localization of the human thrombopoietin gene. FEBS Lett 353 , 57-61. (Pubitemid 24312543)
    • (1994) FEBS Letters , vol.353 , Issue.1 , pp. 57-61
    • Sohma, Y.1    Akahori, H.2    Seki, N.3    Hori, T.-A.4    Ogami, K.5    Kato, T.6    Shimada, Y.7    Kawamura, K.8    Miyazaki, H.9
  • 28
    • 31044439372 scopus 로고    scopus 로고
    • The molecular mechanisms that control thrombopoiesis
    • DOI 10.1172/JCI26674
    • Kaushansky, K. (2005) The molecular mechanisms that control thrombopoiesis. J Clin Invest 115 , 3339-47. (Pubitemid 43121817)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.12 , pp. 3339-3347
    • Kaushansky, K.1
  • 29
    • 0029150706 scopus 로고
    • Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3
    • Bacon, C. M., Tortolani, P. J., Shimosaka, A., Rees, R. C., Longo, D. L., and O'Shea, J. J. (1995) Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3. FEBS Lett 370 , 63-8.
    • (1995) FEBS Lett , vol.370 , pp. 63-8
    • Bacon, C.M.1    Tortolani, P.J.2    Shimosaka, A.3    Rees, R.C.4    Longo, D.L.5    O'Shea, J.J.6
  • 30
    • 4544277651 scopus 로고    scopus 로고
    • Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis
    • DOI 10.1084/jem.20040762
    • Tong, W., and Lodish, H. F. (2004) Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med 200 , 569-80. (Pubitemid 39258306)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.5 , pp. 569-580
    • Tong, W.1    Lodish, H.F.2
  • 31
    • 0036455062 scopus 로고    scopus 로고
    • Synergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formation
    • Metcalf, D., Di Rago, L., and Mifsud, S. (2002) Synergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formation. Stem Cells 20 , 552-60. (Pubitemid 35463068)
    • (2002) Stem Cells , vol.20 , Issue.6 , pp. 552-560
    • Metcalf, D.1    Di Rago, L.2    Mifsud, S.3
  • 32
    • 13744252629 scopus 로고    scopus 로고
    • Stem cell factor synergistically enhances thrombopoietin-induced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase
    • DOI 10.1634/stemcells.2004-0153
    • Drayer, A. L., Boer, A. K., Los, E. L., Esselink, M. T., and Vellenga, E. (2005) Stem cell factor synergistically enhances thrombopoietininduced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase. Stem Cells 23 , 240-51. (Pubitemid 40239519)
    • (2005) Stem Cells , vol.23 , Issue.2 , pp. 240-251
    • Drayer, A.L.1    Boer, A.-K.2    Los, E.L.3    Esselink, M.T.4    Vellenga, E.5
  • 33
    • 0033015427 scopus 로고    scopus 로고
    • + early megakaryocytic marrow cells cultured on normal osteoblasts
    • Ahmed, N., Khokher, M. A., and Hassan, H. T. (1999) Cytokine-induced expansion of human CD34+ stem/progenitor and CD34 + CD41+ early megakaryocytic marrow cells cultured on normal osteoblasts. Stem Cells 17 , 92-9. (Pubitemid 29149398)
    • (1999) Stem Cells , vol.17 , Issue.2 , pp. 92-99
    • Ahmed, N.1    Khokher, M.A.2    Hassan, H.T.3
  • 34
    • 0033962960 scopus 로고    scopus 로고
    • + megakaryocytic cells
    • Lazzari, L., Henschler, R., Lecchi, L., Rebulla, P., Mertelsmann, R., and Sirchia, G. (2000) Interleukin-6 and interleukin-11 act synergistically with thrombopoietin and stem cell factor to modulate ex vivo expansion of human CD41+ and CD61+ megakaryocytic cells. Haematologica 85 , 25-30. (Pubitemid 30096886)
    • (2000) Haematologica , vol.85 , Issue.1 , pp. 25-30
    • Lazzari, L.1    Henschler, R.2    Lecchi, L.3    Rebulla, P.4    Mertelsmann, R.5    Sirchia, G.6
  • 35
    • 0029960265 scopus 로고    scopus 로고
    • Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl
    • Alexander, W. S., Roberts, A. W., Nicola, N. A., Li, R., and Metcalf, D. (1996) Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl. Blood 87 , 2162-70.
    • (1996) Blood , vol.87 , pp. 2162-70
    • Alexander, W.S.1    Roberts, A.W.2    Nicola, N.A.3    Li, R.4    Metcalf, D.5
  • 36
    • 0028086542 scopus 로고
    • Thrombocytopenia in c-mpl-deficient mice
    • Gurney, A. L., Carver-Moore, K., de Sauvage, F. J., and Moore, M. W. (1994) Thrombocytopenia in c-mpl-deficient mice. Science 265 , 1445-7. (Pubitemid 24306797)
    • (1994) Science , vol.265 , Issue.5177 , pp. 1445-1447
    • Gurney, A.L.1    Carver-Moore, K.2    De Sauvage, F.J.3    Moore, M.W.4
  • 38
    • 0032147012 scopus 로고    scopus 로고
    • The α-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion
    • Wang, J. F., Liu, Z. Y., and Groopman, J. E. (1998) The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood 92 , 756-64. (Pubitemid 28355456)
    • (1998) Blood , vol.92 , Issue.3 , pp. 756-764
    • Wang, J.-F.1    Liu, Z.-Y.2    Groopman, J.E.3
  • 39
    • 0345040163 scopus 로고    scopus 로고
    • Phenotypic and functional evidence for the expression of CXCR4 receptor during megakaryocytopoiesis
    • Riviere, C., Subra, F., Cohen-Solal, K., Cordette-Lagarde, V., Letestu, R., Auclair, C., Vainchenker, W., and Louache, F. (1999) Phenotypic and functional evidence for the expression of CXCR4 receptor during megakaryocytopoiesis. Blood 93 , 1511-23. (Pubitemid 29102478)
    • (1999) Blood , vol.93 , Issue.5 , pp. 1511-1523
    • Riviere, C.1    Subra, F.2    Cohen-Solal, K.3    Cordette-Lagarde, V.4    Letestu, R.5    Auclair, C.6    Vainchenker, W.7    Louache, F.8
  • 40
    • 55849106999 scopus 로고    scopus 로고
    • SH2-inositol phosphatase 1 negatively influences early megakaryocyte progenitors
    • Perez, L. E., Desponts, C., Parquet, N., and Kerr, W. G. (2008) SH2-inositol phosphatase 1 negatively influences early megakaryocyte progenitors. PLoS One 3 , e3565.
    • (2008) PLoS One , vol.3
    • Perez, L.E.1    Desponts, C.2    Parquet, N.3    Kerr, W.G.4
  • 42
  • 45
    • 2942618768 scopus 로고    scopus 로고
    • A renaissance for SRC
    • Yeatman, T. J. (2004) A renaissance for SRC. Nat Rev Cancer 4 , 470-80. (Pubitemid 38745532)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 470-480
    • Yeatman, T.J.1
  • 46
    • 0345528837 scopus 로고    scopus 로고
    • Identification and activation of Src family kinases in primary megakaryocytes
    • DOI 10.1016/j.exphem.2003.09.009
    • Lannutti, B. J., Shim, M. H., Blake, N., Reems, J. A., and Drachman, J. G. (2003) Identification and activation of Src family kinases in primary megakaryocytes. Exp Hematol 31 , 1268-74. (Pubitemid 37510033)
    • (2003) Experimental Hematology , vol.31 , Issue.12 , pp. 1268-1274
    • Lannutti, B.J.1    Shim, M.-H.2    Blake, N.3    Reems, J.A.4    Drachman, J.G.5
  • 47
    • 18544379794 scopus 로고    scopus 로고
    • Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656
    • DOI 10.1182/blood-2004-10-3934
    • Lannutti, B. J., Blake, N., Gandhi, M. J., Reems, J. A., and Drachman, J. G. (2005) Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656. Blood 105 , 3875-8. (Pubitemid 40656131)
    • (2005) Blood , vol.105 , Issue.10 , pp. 3875-3878
    • Lannutti, B.J.1    Blake, N.2    Gandhi, M.J.3    Reems, J.A.4    Drachman, J.G.5
  • 48
    • 2342571558 scopus 로고    scopus 로고
    • Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors
    • DOI 10.1182/blood-2003-10-3566
    • Lannutti, B. J., and Drachman, J. G. (2004) Lyn tyrosine kinase regulates thrombopoietininduced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors. Blood 103 , 3736-43. (Pubitemid 38596289)
    • (2004) Blood , vol.103 , Issue.10 , pp. 3736-3743
    • Lannutti, B.J.1    Drachman, J.G.2
  • 49
    • 33744936605 scopus 로고    scopus 로고
    • Increased megakaryocytopoiesis in Lyn-deficient mice
    • DOI 10.1038/sj.onc.1209351
    • Lannutti, B. J., Minear, J., Blake, N., and Drachman, J. G. (2006) Increased megakaryocytopoiesis in Lyn-deficient mice. Oncogene 25 , 3316-24. (Pubitemid 43846316)
    • (2006) Oncogene , vol.25 , Issue.23 , pp. 3316-3324
    • Lannutti, B.J.1    Minear, J.2    Blake, N.3    Drachman, J.G.4
  • 50
    • 57549100621 scopus 로고    scopus 로고
    • Prolonged continuous in vitro human platelet production using three-dimensional scaffolds
    • Sullenbarger, B., Bahng, J. H., Gruner, R., Kotov, N., and Lasky, L. C. (2009) Prolonged continuous in vitro human platelet production using three-dimensional scaffolds. Exp Hematol 37 , 101-10.
    • (2009) Exp Hematol , vol.37 , pp. 101-10
    • Sullenbarger, B.1    Bahng, J.H.2    Gruner, R.3    Kotov, N.4    Lasky, L.C.5
  • 51
    • 38349102225 scopus 로고    scopus 로고
    • Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: Studies using a megakaryocyte lineage specific FAK knockout
    • Hitchcock, I. S., Fox, N. E., Prevost, N., Sear, K., Shattil, S. J., and Kaushansky, K. (2008) Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout. Blood 111 , 596-604.
    • (2008) Blood , vol.111 , pp. 596-604
    • Hitchcock, I.S.1    Fox, N.E.2    Prevost, N.3    Sear, K.4    Shattil, S.J.5    Kaushansky, K.6
  • 52
    • 12344294485 scopus 로고    scopus 로고
    • Engagement of integrin α4β1 enhances thrombopoietin-induced megakaryopoiesis
    • DOI 10.1016/j.exphem.2004.10.002, PII S0301472X04003509
    • Fox, N. E., and Kaushansky, K. (2005) Engagement of integrin alpha4beta1 enhances thrombopoietin-induced megakaryopoiesis. Exp Hematol 33 , 94-9. (Pubitemid 40127648)
    • (2005) Experimental Hematology , vol.33 , Issue.1 , pp. 94-99
    • Fox, N.E.1    Kaushansky, K.2
  • 53
    • 70349576961 scopus 로고    scopus 로고
    • Platelet factor 4 regulates megakaryopoiesis through low-density lipoprotein receptor-related protein 1 (LRP1) on megakaryocytes
    • Lambert, M. P., Wang, Y., Bdeir, K. H., Nguyen, Y., Kowalska, M. A., and Poncz, M. (2009) Platelet factor 4 regulates megakaryopoiesis through low-density lipoprotein receptor-related protein 1 (LRP1) on megakaryocytes. Blood 114 , 2290-8.
    • (2009) Blood , vol.114 , pp. 2290-8
    • Lambert, M.P.1    Wang, Y.2    Bdeir, K.H.3    Nguyen, Y.4    Kowalska, M.A.5    Poncz, M.6
  • 55
    • 67749147173 scopus 로고    scopus 로고
    • Common features of megakaryocytes and hematopoietic stem cells: What's the connection?
    • Huang, H., and Cantor, A. B. (2009) Common features of megakaryocytes and hematopoietic stem cells: what's the connection? J Cell Biochem 107 , 857-64.
    • (2009) J Cell Biochem , vol.107 , pp. 857-64
    • Huang, H.1    Cantor, A.B.2
  • 59
    • 34249981792 scopus 로고    scopus 로고
    • Studies of c-Mpl function distinguish the replication of hematopoietic stem cells from the expansion of differentiating clones
    • DOI 10.1182/blood-2006-08-044503
    • Abkowitz, J. L., and Chen, J. (2007) Studies of c-Mpl function distinguish the replication of hematopoietic stem cells from the expansion of differentiating clones. Blood 109 , 5186-90. (Pubitemid 46890535)
    • (2007) Blood , vol.109 , Issue.12 , pp. 5186-5190
    • Abkowitz, J.L.1    Chen, J.2
  • 60
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in heaematopolesis and in cerebellar development
    • DOI 10.1038/31269
    • Zou, Y. R., Kottmann, A. H., Kuroda, M., Taniuchi, I., and Littman, D. R. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393 , 595-9. (Pubitemid 28319251)
    • (1998) Nature , vol.393 , Issue.6685 , pp. 595-599
    • Zou, Y.-R.1    Kottman, A.H.2    Kuroda, M.3    Taniuchi, I.4    Littman, D.R.5
  • 61
    • 2642710893 scopus 로고    scopus 로고
    • + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1
    • Mohle, R., Bautz, F., Rafii, S., Moore, M. A., Brugger, W., and Kanz, L. (1998) The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 91 , 4523-30. (Pubitemid 28270300)
    • (1998) Blood , vol.91 , Issue.12 , pp. 4523-4530
    • Mohle, R.1    Bautz, F.2    Rafii, S.3    Moore, M.A.S.4    Brugger, W.5    Kanz, L.6
  • 62
    • 67649503011 scopus 로고    scopus 로고
    • Thrombopoietin controls proliferation of embryonic multipotent hematopoietic progenitors
    • Huang, X., Sakamoto, H., and Ogawa, M. (2009) Thrombopoietin controls proliferation of embryonic multipotent hematopoietic progenitors. Genes Cells 14 , 851-60.
    • (2009) Genes Cells , vol.14 , pp. 851-60
    • Huang, X.1    Sakamoto, H.2    Ogawa, M.3
  • 63
    • 84940808276 scopus 로고
    • The fine structure of the megakaryocyte in the mouse spleen
    • Yamada, E. (1957) The fine structure of the megakaryocyte in the mouse spleen. Acta Anat (Basel) 29 , 267-90.
    • (1957) Acta Anat (Basel) , vol.29 , pp. 267-90
    • Yamada, E.1
  • 64
    • 0014332027 scopus 로고
    • An electron microscope study of the megacaryocyte of the rat bone marrow. I. The development of the demarcation membrane system and the platelet surface coat
    • Behnke, O. (1968) An electron microscope study of the megacaryocyte of the rat bone marrow. I. The development of the demarcation membrane system and the platelet surface coat. J Ultrastruct Res 24 , 412-33.
    • (1968) J Ultrastruct Res , vol.24 , pp. 412-33
    • Behnke, O.1
  • 66
    • 0033552631 scopus 로고    scopus 로고
    • Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes
    • DOI 10.1083/jcb.147.6.1299
    • Italiano, J. E., Jr., Lecine, P., Shivdasani, R. A., and Hartwig, J. H. (1999) Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol 147 , 1299-312. (Pubitemid 30012814)
    • (1999) Journal of Cell Biology , vol.147 , Issue.6 , pp. 1299-1312
    • Italiano Jr., J.E.1    Lecine, P.2    Shivdasani, R.A.3    Hartwig, J.H.4
  • 67
    • 0019991003 scopus 로고
    • The demarcation membrane system of the megakaryocyte: A misnomer?
    • Radley, J. M., and Haller, C. J. (1982) The demarcation membrane system of the megakaryocyte: a misnomer? Blood 60 , 213-9. (Pubitemid 12085942)
    • (1982) Blood , vol.60 , Issue.1 , pp. 213-219
    • Radley, J.M.1    Haller, C.J.2
  • 68
    • 28844485066 scopus 로고    scopus 로고
    • Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes
    • DOI 10.1182/blood-2005-06-2204
    • Patel, S. R., Richardson, J. L., Schulze, H., Kahle, E., Galjart, N., Drabek, K., Shivdasani, R. A., Hartwig, J. H., and Italiano, J. E., Jr. (2005) Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood 106 , 4076-85. (Pubitemid 41775912)
    • (2005) Blood , vol.106 , Issue.13 , pp. 4076-4085
    • Patel, S.R.1    Richardson, J.L.2    Schulze, H.3    Kahle, E.4    Galjart, N.5    Drabek, K.6    Shivdasani, R.A.7    Hartwig, J.H.8    Italiano Jr., J.E.9
  • 69
    • 33646540122 scopus 로고    scopus 로고
    • Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis
    • DOI 10.1182/blood-2005-07-2755
    • Schulze, H., Korpal, M., Hurov, J., Kim, S. W., Zhang, J., Cantley, L. C., Graf, T., and Shivdasani, R. A. (2006) Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood 107 , 3868-75. (Pubitemid 43726790)
    • (2006) Blood , vol.107 , Issue.10 , pp. 3868-3875
    • Schulze, H.1    Korpal, M.2    Hurov, J.3    Kim, S.-W.4    Zhang, J.5    Cantley, L.C.6    Graf, T.7    Shivdasani, R.A.8
  • 70
    • 0030982911 scopus 로고    scopus 로고
    • Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand
    • Cramer, E. M., Norol, F., Guichard, J., Breton-Gorius, J., Vainchenker, W., Masse, J. M., and Debili, N. (1997) Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand. Blood 89 , 2336-46. (Pubitemid 27143280)
    • (1997) Blood , vol.89 , Issue.7 , pp. 2336-2346
    • Cramer, E.M.1    Norol, F.2    Guichard, J.3    Breton-Gorius, J.4    Vainchenker, W.5    Masse, J.-M.6    Debili, N.7
  • 72
    • 33751170220 scopus 로고    scopus 로고
    • Differential effects of recombinant thrombopoietin and bone marrow stromal-conditioned media on neonatal versus adult megakaryocytes
    • Pastos, K. M., Slayton, W. B., Rimsza, L. M., Young, L., and Sola-Visner, M. C. (2006) Differential effects of recombinant thrombopoietin and bone marrow stromal-conditioned media on neonatal versus adult megakaryocytes. Blood 108 , 3360-2.
    • (2006) Blood , vol.108 , pp. 3360-2
    • Pastos, K.M.1    Slayton, W.B.2    Rimsza, L.M.3    Young, L.4    Sola-Visner, M.C.5
  • 73
    • 75649135006 scopus 로고    scopus 로고
    • Differences between newborn and adult mice in their response to immune thrombocytopenia
    • Hu, Z., Slayton, W. B., Rimsza, L. M., Bailey, M., Sallmon, H., and Sola-Visner, M. C. Differences between newborn and adult mice in their response to immune thrombocytopenia. Neonatology 98 , 100-8.
    • Neonatology , vol.98 , pp. 100-8
    • Hu, Z.1    Slayton, W.B.2    Rimsza, L.M.3    Bailey, M.4    Sallmon, H.5    Sola-Visner, M.C.6
  • 74
    • 26244456733 scopus 로고    scopus 로고
    • Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design
    • DOI 10.1016/j.exphem.2005.06.020, PII S0301472X05003036
    • Cortin, V., Garnier, A., Pineault, N., Lemieux, R., Boyer, L., and Proulx, C. (2005) Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design. Exp Hematol 33 , 1182-91. (Pubitemid 41416966)
    • (2005) Experimental Hematology , vol.33 , Issue.10 , pp. 1182-1191
    • Cortin, V.1    Garnier, A.2    Pineault, N.3    Lemieux, R.4    Boyer, L.5    Proulx, C.6
  • 75
    • 0344394521 scopus 로고    scopus 로고
    • Production of functional platelets by differentiated embryonic stem (ES) cells in vitro
    • DOI 10.1182/blood-2003-06-1773
    • Fujimoto, T. T., Kohata, S., Suzuki, H., Miyazaki, H., and Fujimura, K. (2003) Production of functional platelets by differentiated embryonic stem (ES) cells in vitro. Blood 102 , 4044-51. (Pubitemid 37486987)
    • (2003) Blood , vol.102 , Issue.12 , pp. 4044-4051
    • Fujimoto, T.-T.1    Kohata, S.2    Suzuki, H.3    Miyazaki, H.4    Fujimura, K.5
  • 76
    • 33645576158 scopus 로고    scopus 로고
    • Megakaryocytes derived from human embryonic stem cells: A genetically tractable system to study megakaryocytopoiesis and integrin function
    • Gaur, M., Kamata, T., Wang, S., Moran, B., Shattil, S. J., and Leavitt, A. D. (2006) Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J Thromb Haemost 4 , 436-42.
    • (2006) J Thromb Haemost , vol.4 , pp. 436-42
    • Gaur, M.1    Kamata, T.2    Wang, S.3    Moran, B.4    Shattil, S.J.5    Leavitt, A.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.