Genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 are associated with ovarian cancer susceptibility among Chinese Han women

Cancer Epidemiology

Volumn 37, Issue 5, 2013, Pages 639-646

  Zheng, Liyuan ^a   Song, Aiping ^a   Ruan, Yuan ^a   Chen, Lan ^b   Liu, Dongge ^b   Li, Xianghong ^c   Guo, Hongyan ^d   Han, Jiyuan ^a   Li, Yan ^a   Tian, Xinxia ^a   Fang, Weigang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING HOSPITAL   (China)

^c PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^d PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

AURKA; BRCA1; CCNE1; CDK2; Ovarian cancer; Single nucleotide polymorphism (SNP)

Indexed keywords

CYCLIN DEPENDENT KINASE 2;

ADULT; ARTICLE; AURKA GENE; CANCER RISK; CANCER SUSCEPTIBILITY; CCNE1 GENE; CHINESE; CONTROLLED STUDY; CYSTADENOCARCINOMA; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; OVARY CANCER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE;

AURKA; BRCA1; CCNE1; CDK2; OVARIAN CANCER; SINGLE NUCLEOTIDE POLYMORPHISM (SNP);

ASIAN CONTINENTAL ANCESTRY GROUP; AURORA KINASE A; CASE-CONTROL STUDIES; CHINA; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYSTADENOCARCINOMA, SEROUS; FEMALE; GENES, BRCA1; GENETIC PREDISPOSITION TO DISEASE; HAPMAP PROJECT; HUMANS; MIDDLE AGED; ONCOGENE PROTEINS; OVARIAN NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84884159010     PISSN: 18777821     EISSN: 1877783X     Source Type: Journal    
DOI: 10.1016/j.canep.2013.04.018     Document Type: Article

References (36)

1. Jordan S.J., Cushing-Haugen K.L., Wicklund K.G., Doherty J.A., Rossing M.A. Breast-feeding and risk of epithelial ovarian cancer. Cancer Causes Control 2010, 23(June (6)):919-927.
2. Rota M., Pasquali E., Scotti L., Pelucchi C., Tramacere I., Islami F., et al. Alcohol drinking and epithelial ovarian cancer risk: a systematic review and meta-analysis. Gynecol Oncol 2012, 125(June (3)):758-763.
3. Wang M., He Y., Shi L., Shi C. Multivariate analysis by Cox proportional hazard model on prognosis of patient with epithelial ovarian cancer. Eur J Gynaecol Oncol 2011, 32(2):171-177.
4. Gayther S.A., Pharoah P.D. The inherited genetics of ovarian and endometrial cancer. Curr Opin Genet Dev 2010, 20(June (3)):231-238.
5. Schork N.J., Murray S.S., Frazer K.A., Topol E.J. Common vs. rare allele hypotheses for complex diseases. Curr Opin Genet Dev 2009, 19(June (3)):212-219.
6. A map of human genome variation from population-scale, sequencing. Nature 2010, 467(October (7319)):1061-1073.
7. Clark A.G. The role of haplotypes in candidate gene studies. Genet Epidemiol 2004, 27(December (4)):321-333.
8. Johnson G.C., Esposito L., Barratt B.J., Smith A.N., Heward J., Di Genova G., et al. Haplotype tagging for the identification of common disease genes. Nat Genet 2001, 29(October (2)):233-237.
9. Chan J.Y. A clinical overview of centrosome amplification in human cancers. Int J Biol Sci 2011, 7(8):1122-1144.
10. Nigg E.A. Centrosome aberrations: cause or consequence of cancer progression?. Nat Rev 2002, 2(November (11)):815-825.
11. Fukasawa K. Oncogenes and tumour suppressors take on centrosomes. Nat Rev 2007, 7(December (12)):911-924.
12. Ruan Y., Song A.P., Wang H., Xie Y.T., Han J.Y., Sajdik C., et al. Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population. J Pathol 2011, 225(December (4)):535-543.
13. Han J.Y., Wang H., Xie Y.T., Li Y., Zheng L.Y., Ruan Y., et al. Association of germline variation in CCNE1 and CDK2 with breast cancer risk, progression and survival among Chinese Han Women. PloS ONE 2012, 7(11):e49296.
14. Vader G., Lens S.M. The Aurora kinase family in cell division and cancer. Biochim Biophys Acta 2008, 1786(September (1)):60-72.
15. Nikonova A.S., Astsaturov I., Serebriiskii I.G., Dunbrack R.L., Golemis E.A. Aurora A kinase (AURKA) in normal and pathological cell division. Cell Mol Life Sci 2013, 70(Feb 4):661-687.
16. Zhou H., Kuang J., Zhong L., Kuo W.L., Gray J.W., Sahin A., et al. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998, 20(October (2)):189-193.
17. Starita L.M., Machida Y., Sankaran S., Elias J.E., Griffin K., Schlegel B.P., et al. BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Mol Cell Biol 2004, 24(October (19)):8457-8466.
18. Sankaran S., Starita L.M., Groen A.C., Ko M.J., Parvin J.D. Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Mol Cell Biol 2005, 25(October (19)):8656-8668.
19. Kais Z., Parvin J.D. Regulation of centrosomes by the BRCA1-dependent ubiquitin ligase. Cancer Biol Ther 2008, 7(October (10)):1540-1543.
20. Anand S., Penrhyn-Lowe S., Venkitaraman A.R. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 2003, 3(January (1)):51-62.
21. Meraldi P., Honda R., Nigg E.A. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J 2002, 21(February (4)):483-492.
22. Nam E.J., Kim Y.T. Alteration of cell-cycle regulation in epithelial ovarian cancer. Int J Gynecol Cancer 2008, 18(November-December (6)):1169-1182.
23. Hinchcliffe E.H., Li C., Thompson E.A., Maller J.L., Sluder G. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. Science (New York, NY) 1999, 283(February (5403)):851-854.
24. Courjal F., Louason G., Speiser P., Katsaros D., Zeillinger R., Theillet C. Cyclin gene amplification and overexpression in breast and ovarian cancers: evidence for the selection of cyclin D1 in breast and cyclin E in ovarian tumors. Int J Cancer 1996, 69(August (4)):247-253.
25. Farley J., Smith L.M., Darcy K.M., Sobel E., O'Connor D., Henderson B., et al. Cyclin E expression is a significant predictor of survival in advanced, suboptimally debulked ovarian epithelial cancers: a Gynecologic Oncology Group study. Cancer Res 2003, 63(March (6)):1235-1241.
26. Lo Y.L., Yu J.C., Chen S.T., Yang H.C., Fann C.S., Mau Y.C., et al. Breast cancer risk associated with genotypic polymorphism of the mitosis-regulating gene Aurora-A/STK15/BTAK. Int J Cancer 2005, 115(June (2)):276-283.
27. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (Oxford, England) 2005, 21(January (2)):263-265.
28. Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Statist Soc Ser B 1995, 57:289-300.
29. Dicioccio R.A., Song H., Waterfall C., Kimura M.T., Nagase H., McGuire V., et al. STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev 2004, 13(October (10)):1589-1594.
30. Ramus S.J., Vierkant R.A., Johnatty S.E., Pike M.C., Van Den Berg D.J., Wu A.H., et al. Consortium analysis of 7 candidate SNPs for ovarian cancer. Int J Cancer 2008, 123(July (2)):380-388.
31. Cox D.G., Kraft P., Hankinson S.E., Hunter D.J. Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer. Breast Cancer Res 2005, 7(2):R171-R175.
32. Baynes C., Healey C.S., Pooley K.A., Scollen S., Luben R.N., Thompson D.J., et al. Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk. Breast Cancer Res 2007, 9(2):R27.
33. Bonnen P.E., Wang P.J., Kimmel M., Chakraborty R., Nelson D.L. Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res 2002, 12(December (12)):1846-1853.
34. Freedman M.L., Penney K.L., Stram D.O., Riley S., McKean-Cowdin R., Le Marchand L., et al. A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk. Cancer Res 2005, 65(August (16)):7516-7522.
35. Gayther S.A., Song H., Ramus S.J., Kjaer S.K., Whittemore A.S., Quaye L., et al. Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res 2007, 67(April (7)):3027-3035.
36. Goode E.L., Fridley B.L., Vierkant R.A., Cunningham J.M., Phelan C.M., Anderson S., et al. Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev 2009, 18(March (3)):935-944.