STK15 polymorphisms and association with risk of invasive ovarian cancer

Cancer Epidemiology Biomarkers and Prevention

Volumn 13, Issue 10, 2004, Pages 1589-1594

  DiCioccio, Richard A ^a   Song, Honglin ^e   Waterfall, Christy ^c   Kimura, Makoto T ^a   Nagase, Hiroki ^a   McGuire, Valerie ^b   Hogdall, Estrid ^d   Shah, Mitul N ^e   Luben, Robert N ^e   Easton, Douglas F ^e   Jacobs, Ian J ^c   Ponder, Bruce A J ^e   Whittemore, Alice S ^b   Gayther, Simon A ^c   Pharoah, Paul D P ^e   Kruger Kjaer, Susan ^d  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADULT; AGED; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CANCER INVASION; CANCER RISK; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DENMARK; DOMINANT INHERITANCE; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MITOSIS; ONCOGENE; OVARY CANCER; PENETRANCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STK15 GENE; UNITED KINGDOM; UNITED STATES;

ADULT; AGED; CASE-CONTROL STUDIES; DENMARK; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GREAT BRITAIN; HAPLOTYPES; HUMANS; MIDDLE AGED; OVARIAN NEOPLASMS; POLYMORPHISM, GENETIC; PROTEIN-SERINE-THREONINE KINASES; RISK FACTORS; UNITED STATES;

EID: 4944245357     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Kimura M, Matsuda Y, Eki T, et al. Assignment of STK6 to human chromosome 20q13.2→q13.3 and a pseudogene STK6P to Iq41→q42. Cytogenet Cell Genet 1997;79:201-3.
2. Kimura M, Kotani S, Hattori T, et al. Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to aurora of Drosophila and yeast Ipl1. J Biol Chem 1997;272:13766-71.
3. Sen S, Zhou H, White RA. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene 1997;14:2195-200.
4. Bischoff JR, Anderson L, Zhu Y, et al. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 1998;17:3052-65.
5. Zhou H, Kuang J, Zhong L, et al. Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998;20:189-93.
6. Giet R, Prigent C. Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J Cell Sci 1999;112:3591-601.
7. Graham MT, Cheetham GMT, Knegtel RMA, et al. Crystal structure of aurora-2, an oncogenic serine/threonine kinase. J Biol Chem 2002;277:42419-22.
8. Tanaka T, Kimura M, Matsunaga K, Fukada D, Mori H, Okano Y. Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res 1999;59:2141-4.
9. Tanner MM, Grenman S, Koul A, et al. Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin Cancer Res 2000;6:1833-9.
10. Miyoshi Y, Iwao K, Egawa C, Noguchi S. Association of centrosomal kinase STK15/BTAK MRNA expression with chromosomal instability in human breast cancers. Int J Cancer 2001;92:370-3.
11. Bar-Shira A, Pinthus JH, Rozovsky U, et al. Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft. Cancer Res 2002;62:6803-7.
12. Watanabe T, Imoto I, Katahira T, et al. Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers. Jpn J Cancer Res 2002;93:1114-22.
13. Moreno-Bueno G, Sanchez-Estevez C, Cassia R, et al. Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas. Cancer Res 2003;63:5697-702.
14. Ewart-Toland A, Briassouli P, de Koning JP, et al. Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003;34:403-12.
15. Iwabuchi H, Sakamoto M, Sakunaga H, et al. Genetic analysis of benign, low-grade, and high-grade ovarian tumors. Cancer Res 1995;55:6172-80.
16. Arnold N, Hagele L, Walz L, et al. Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer. Genes Chromosomes Cancer 1996;16:567-76.
17. Sonoda G, Palazzo J, du Manoir S, et al. Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q24, and 20q13 in human ovarian carcinomas. Genes Chromosomes Cancer 1997;20:320-8.
18. Tapper J, Sarantaus L, Vahteristo P, et al. Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32. Cancer Res 1998;58:2715-9.
19. Wolf NG, Abdul-Karim FW, Farver C, Schrock E, du Manoir S, Schwartz S. Analysis of ovarian borderline tumors using comparative genomic hybridization and fluorescence in situ hybridization. Genes Chromosomes Cancer 1999;25:307-15.
20. Suehiro Y, Sakamoto M, Umayahara K, et al. Genetic aberrations detected by comparative genomic hybridization in ovarian clear cell adenocarcinoma. Oncology 2000;59:50-6.
21. Kiechle M, Jacobsen A, Schwarz-Boeger U, Hedderich J, Pfisterer J, Arnold N. Comparative genomic hybridization detects genetic imbalances in primary ovarian carcinomas as correlated with grade of differentiation. Cancer 2001;91:534-40.
22. Shridhar V, Lee J, Pandita A, et al. Genetic analysis of early-versus late-stage ovarian tumors. Cancer Res 2001;61:5895-904.
23. Sham JST, Tang TCM, Fang Y, et al. Recurrent chromosome alterations in primary ovarian carcinoma in Chinese women. Cancer Genet Cytogenet 2002;133:39-44.
24. Ramus SJ, Pharoah P, Harrington P, et al. BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases. Cancer Res 2002;63:417-23.
25. Lum A, LeMarchand L. A simple mouthwash method for obtaining genomic DNA in molecular epidemiological studies. Cancer Epidemiol Biomarkers Prev 1998;7:719-24.
26. Excoffier L, Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995;12:921-7.
27. Pharoah PD, Ponder BA. The genetics of ovarian cancer. Best Pract Res Clin Obstet Gynaecol 2002;16:449-68.
28. Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003;361:598-604.
29. Pharoah PDF, Antoniou A, Bobrow M, Zimmern RL, Ponder BAJ, Easton DF. Polygenic susceptibility to breast cancer: implications for prevention. Nat Genet 2002;31:33-6.
30. NIH Consensus Development Panel on Ovarian Cancer. Ovarian cancer: screening, treatment, and follow-up. JAMA 1995;273:491-7.
31. La Vecchia C, Franceschi S. Oral contraceptives and ovarian cancer. Eur J Cancer Prev 1999;8:297-304.
32. Kauff ND, Satagopan JM, Robson ME, et al. Risk-reducing salpingooophorectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med 2002;346:1609-15.
33. Rebbeck TR, Lynch HT, Neuhausen SL, et al. For the prevention and observation of surgical end points study group. Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N Engl J Med 2002;346:1616-2022.