-
1
-
-
0021981769
-
Distribution and origin of calcitonin gene-related peptide (CGRP) immunoreactivity in the sensory innervation of the mammalian eye
-
Terenghi G, Polak JM, Ghatei MA, et al. Distribution and origin of calcitonin gene-related peptide (CGRP) immunoreactivity in the sensory innervation of the mammalian eye. J Comp Neurol. 1985; 233: 506-516.
-
(1985)
J Comp Neurol
, vol.233
, pp. 506-516
-
-
Terenghi, G.1
Polak, J.M.2
Ghatei, M.A.3
-
2
-
-
0023002243
-
The calcitonin-like sequence of the beta CGRP gene
-
Alevizaki M, Shiraishi A, Rassool FV, Ferrier GJ, MacIntyre I, Legon S,. The calcitonin-like sequence of the beta CGRP gene. FEBS Lett. 1986; 206: 47-52.
-
(1986)
FEBS Lett
, vol.206
, pp. 47-52
-
-
Alevizaki, M.1
Shiraishi, A.2
Rassool, F.V.3
Ferrier, G.J.4
Macintyre, I.5
Legon, S.6
-
3
-
-
84857084559
-
Calcitonin gene-related peptide in migraine: Intersection of peripheral inflammation and central modulation
-
Raddant AC, Russo AF,. Calcitonin gene-related peptide in migraine: Intersection of peripheral inflammation and central modulation. Expert Rev Mol Med. 2011; 13: e36.
-
(2011)
Expert Rev Mol Med
, vol.13
-
-
Raddant, A.C.1
Russo, A.F.2
-
4
-
-
0025342422
-
Alpha-CGRP and beta-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion
-
Noguchi K, Senba E, Morita Y, Sato M, Tohyama M,. Alpha-CGRP and beta-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion. Brain Res Mol Brain Res. 1990; 7: 299-304.
-
(1990)
Brain Res Mol Brain Res
, vol.7
, pp. 299-304
-
-
Noguchi, K.1
Senba, E.2
Morita, Y.3
Sato, M.4
Tohyama, M.5
-
5
-
-
0022593039
-
Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP)
-
Tippins JR, Di Marzo V, Panico M, Morris HR, MacIntyre I,. Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP). Biochem Biophys Res Commun. 1986; 134: 1306-1311.
-
(1986)
Biochem Biophys Res Commun
, vol.134
, pp. 1306-1311
-
-
Tippins, J.R.1
Di Marzo, V.2
Panico, M.3
Morris, H.R.4
Macintyre, I.5
-
6
-
-
0034327470
-
The molecular pharmacology of CGRP and related peptide receptor subtypes
-
Juaneda C, Dumont Y, Quirion R,. The molecular pharmacology of CGRP and related peptide receptor subtypes. Trends Pharmacol Sci. 2000; 21: 432-438.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 432-438
-
-
Juaneda, C.1
Dumont, Y.2
Quirion, R.3
-
7
-
-
67049108842
-
Calcitonin gene-related peptide: An update on the biology
-
Recober A, Russo AF,. Calcitonin gene-related peptide: An update on the biology. Curr Opin Neurol. 2009; 22: 241-246.
-
(2009)
Curr Opin Neurol
, vol.22
, pp. 241-246
-
-
Recober, A.1
Russo, A.F.2
-
8
-
-
0024438353
-
Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor
-
Emeson RB, Hedjran F, Yeakley JM, Guise JW, Rosenfeld MG,. Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature. 1989; 341: 76-80.
-
(1989)
Nature
, vol.341
, pp. 76-80
-
-
Emeson, R.B.1
Hedjran, F.2
Yeakley, J.M.3
Guise, J.W.4
Rosenfeld, M.G.5
-
9
-
-
0030665019
-
Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors
-
van Rossum D, Hanisch UK, Quirion R,. Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors. Neurosci Biobehav Rev. 1997; 21: 649-678.
-
(1997)
Neurosci Biobehav Rev
, vol.21
, pp. 649-678
-
-
Van Rossum, D.1
Hanisch, U.K.2
Quirion, R.3
-
10
-
-
0025116298
-
Extracerebral manifestations in migraine. A peptidergic involvement?
-
Edvinsson L, Goadsby PJ,. Extracerebral manifestations in migraine. A peptidergic involvement? J Intern Med. 1990; 228: 299-304.
-
(1990)
J Intern Med
, vol.228
, pp. 299-304
-
-
Edvinsson, L.1
Goadsby, P.J.2
-
11
-
-
0025143541
-
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache
-
Goadsby PJ, Edvinsson L, Ekman R,. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann Neurol. 1990; 28: 183-187.
-
(1990)
Ann Neurol
, vol.28
, pp. 183-187
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
12
-
-
84872105680
-
Clinical trials update - 2012: Year in review
-
Peroutka SJ,. Clinical trials update-2012: Year in review. Headache. 2013; 53: 177-180.
-
(2013)
Headache
, vol.53
, pp. 177-180
-
-
Peroutka, S.J.1
-
13
-
-
84871261412
-
Emerging target-based paradigms to prevent and treat migraine
-
Silberstein SD,. Emerging target-based paradigms to prevent and treat migraine. Clin Pharmacol Ther. 2013; 93: 78-85.
-
(2013)
Clin Pharmacol Ther
, vol.93
, pp. 78-85
-
-
Silberstein, S.D.1
-
14
-
-
0021999238
-
Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin
-
Lundberg JM, Franco-Cereceda A, Hua X, Hokfelt T, Fischer JA,. Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin. Eur J Pharmacol. 1985; 108: 315-319.
-
(1985)
Eur J Pharmacol
, vol.108
, pp. 315-319
-
-
Lundberg, J.M.1
Franco-Cereceda, A.2
Hua, X.3
Hokfelt, T.4
Fischer, J.A.5
-
15
-
-
0026706282
-
Release of calcitonin gene-related peptide from sensory neurons
-
Lundberg JM, Franco-Cereceda A, Alving K, Delay-Goyet P, Lou YP,. Release of calcitonin gene-related peptide from sensory neurons. Ann N Y Acad Sci. 1992; 657: 187-193.
-
(1992)
Ann N y Acad Sci
, vol.657
, pp. 187-193
-
-
Lundberg, J.M.1
Franco-Cereceda, A.2
Alving, K.3
Delay-Goyet, P.4
Lou, Y.P.5
-
16
-
-
0023886266
-
Differential expression of alpha-CGRP and beta-CGRP by primary sensory neurons and enteric autonomic neurons of the rat
-
Mulderry PK, Ghatei MA, Spokes RA, et al. Differential expression of alpha-CGRP and beta-CGRP by primary sensory neurons and enteric autonomic neurons of the rat. Neuroscience. 1988; 25: 195-205.
-
(1988)
Neuroscience
, vol.25
, pp. 195-205
-
-
Mulderry, P.K.1
Ghatei, M.A.2
Spokes, R.A.3
-
17
-
-
0028844398
-
Clinical perspectives of calcitonin gene related peptide pharmacology
-
Feuerstein G, Willette R, Aiyar N,. Clinical perspectives of calcitonin gene related peptide pharmacology. Can J Physiol Pharmacol. 1995; 73: 1070-1074.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1070-1074
-
-
Feuerstein, G.1
Willette, R.2
Aiyar, N.3
-
18
-
-
0028856641
-
Pharmacology of receptors for calcitonin gene-related peptide and amylin
-
Poyner D,. Pharmacology of receptors for calcitonin gene-related peptide and amylin. Trends Pharmacol Sci. 1995; 16: 424-428.
-
(1995)
Trends Pharmacol Sci
, vol.16
, pp. 424-428
-
-
Poyner, D.1
-
19
-
-
51649126753
-
Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide
-
Toda M, Suzuki T, Hosono K, et al. Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide. Proc Natl Acad Sci U S A. 2008; 105: 13550-13555.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13550-13555
-
-
Toda, M.1
Suzuki, T.2
Hosono, K.3
-
20
-
-
0031106389
-
Calcitonin gene-related peptide and reperfusion injury
-
Allen DM, Chen LE, Seaber AV, Urbaniak JR,. Calcitonin gene-related peptide and reperfusion injury. J Orthop Res. 1997; 15: 243-248.
-
(1997)
J Orthop Res
, vol.15
, pp. 243-248
-
-
Allen, D.M.1
Chen, L.E.2
Seaber, A.V.3
Urbaniak, J.R.4
-
21
-
-
0032076264
-
Calcitonin gene-related peptide in myocardial ischaemia and reperfusion in the pig
-
Kallner G, Gonon A, Franco-Cereceda A,. Calcitonin gene-related peptide in myocardial ischaemia and reperfusion in the pig. Cardiovasc Res. 1998; 38: 493-499.
-
(1998)
Cardiovasc Res
, vol.38
, pp. 493-499
-
-
Kallner, G.1
Gonon, A.2
Franco-Cereceda, A.3
-
22
-
-
78650763344
-
Effect of calcitonin gene-related peptide receptor antagonism on the systemic blood pressure responses to mechanistically diverse vasomodulators in conscious rats
-
Lynch JJ Jr, Detwiler TJ, Kane SA, Regan CP,. Effect of calcitonin gene-related peptide receptor antagonism on the systemic blood pressure responses to mechanistically diverse vasomodulators in conscious rats. J Cardiovasc Pharmacol. 2010; 56: 518-525.
-
(2010)
J Cardiovasc Pharmacol
, vol.56
, pp. 518-525
-
-
Lynch, Jr.J.J.1
Detwiler, T.J.2
Kane, S.A.3
Regan, C.P.4
-
23
-
-
23944444767
-
Calcitonin gene-related peptide and substance P contribute to reduced blood pressure in sympathectomized rats
-
Supowit SC, Ethridge RT, Zhao H, Katki KA, Dipette DJ,. Calcitonin gene-related peptide and substance P contribute to reduced blood pressure in sympathectomized rats. Am J Physiol Heart Circ Physiol. 2005; 289: H1169-H1175.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Supowit, S.C.1
Ethridge, R.T.2
Zhao, H.3
Katki, K.A.4
Dipette, D.J.5
-
24
-
-
3042597423
-
Vascular actions of calcitonin gene-related peptide and adrenomedullin
-
Brain SD, Grant AD,. Vascular actions of calcitonin gene-related peptide and adrenomedullin. Physiol Rev. 2004; 84: 903-934.
-
(2004)
Physiol Rev
, vol.84
, pp. 903-934
-
-
Brain, S.D.1
Grant, A.D.2
-
25
-
-
0021997471
-
Calcitonin gene-related peptide is a potent vasodilator
-
Brain SD, Williams TJ, Tippins JR, Morris HR, MacIntyre I,. Calcitonin gene-related peptide is a potent vasodilator. Nature. 1985; 313: 54-56.
-
(1985)
Nature
, vol.313
, pp. 54-56
-
-
Brain, S.D.1
Williams, T.J.2
Tippins, J.R.3
Morris, H.R.4
Macintyre, I.5
-
26
-
-
72949106255
-
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974)
-
Sinclair SR, Kane SA, Van der Schueren BJ, et al. Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974). Br J Clin Pharmacol. 2010; 69: 15-22.
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 15-22
-
-
Sinclair, S.R.1
Kane, S.A.2
Van Der Schueren, B.J.3
-
27
-
-
0023874663
-
Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system
-
Goadsby PJ, Edvinsson L, Ekman R,. Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system. Ann Neurol. 1988; 23: 193-196.
-
(1988)
Ann Neurol
, vol.23
, pp. 193-196
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
28
-
-
33745107264
-
Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide
-
Denekas T, Troltzsch M, Vater A, Klussmann S, Messlinger K,. Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide. Br J Pharmacol. 2006; 148: 536-543.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 536-543
-
-
Denekas, T.1
Troltzsch, M.2
Vater, A.3
Klussmann, S.4
Messlinger, K.5
-
29
-
-
14644431824
-
Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack
-
Juhasz G, Zsombok T, Jakab B, Nemeth J, Szolcsanyi J, Bagdy G,. Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack. Cephalalgia. 2005; 25: 179-183.
-
(2005)
Cephalalgia
, vol.25
, pp. 179-183
-
-
Juhasz, G.1
Zsombok, T.2
Jakab, B.3
Nemeth, J.4
Szolcsanyi, J.5
Bagdy, G.6
-
30
-
-
0344737766
-
NO-induced migraine attack: Strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release
-
Juhasz G, Zsombok T, Modos EA, et al. NO-induced migraine attack: Strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release. Pain. 2003; 106: 461-470.
-
(2003)
Pain
, vol.106
, pp. 461-470
-
-
Juhasz, G.1
Zsombok, T.2
Modos, E.A.3
-
31
-
-
78650413846
-
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
-
Hansen JM, Hauge AW, Olesen J, Ashina M,. Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. Cephalalgia. 2010; 30: 1179-1186.
-
(2010)
Cephalalgia
, vol.30
, pp. 1179-1186
-
-
Hansen, J.M.1
Hauge, A.W.2
Olesen, J.3
Ashina, M.4
-
32
-
-
0034649442
-
Plasma levels of calcitonin gene-related peptide in chronic tension-type headache
-
Ashina M, Bendtsen L, Jensen R, Schifter S, Jansen-Olesen I, Olesen J,. Plasma levels of calcitonin gene-related peptide in chronic tension-type headache. Neurology. 2000; 55: 1335-1340.
-
(2000)
Neurology
, vol.55
, pp. 1335-1340
-
-
Ashina, M.1
Bendtsen, L.2
Jensen, R.3
Schifter, S.4
Jansen-Olesen, I.5
Olesen, J.6
-
33
-
-
0036285460
-
CGRP may play a causative role in migraine
-
Lassen LH, Haderslev PA, Jacobsen VB, Iversen HK, Sperling B, Olesen J,. CGRP may play a causative role in migraine. Cephalalgia. 2002; 22: 54-61.
-
(2002)
Cephalalgia
, vol.22
, pp. 54-61
-
-
Lassen, L.H.1
Haderslev, P.A.2
Jacobsen, V.B.3
Iversen, H.K.4
Sperling, B.5
Olesen, J.6
-
34
-
-
0025915702
-
The effect of calcitonin gene-related peptide on arrhythmia caused by adenosine diphosphate and desacetyldigilanide-C in rats
-
Zhang JF, Liu J, Liu XZ, Sheng SL, Zhang WJ, Chen YJ,. The effect of calcitonin gene-related peptide on arrhythmia caused by adenosine diphosphate and desacetyldigilanide-C in rats. Int J Cardiol. 1991; 33: 43-46.
-
(1991)
Int J Cardiol
, vol.33
, pp. 43-46
-
-
Zhang, J.F.1
Liu, J.2
Liu, X.Z.3
Sheng, S.L.4
Zhang, W.J.5
Chen, Y.J.6
-
35
-
-
0034096267
-
Calcitonin gene-related peptide enhances the recovery of contractile function in stunned myocardium
-
Atkins BZ, Silvestry SC, Samy RN, Shah AS, Sabiston DC Jr, Glower DD,. Calcitonin gene-related peptide enhances the recovery of contractile function in stunned myocardium. J Thorac Cardiovasc Surg. 2000; 119: 1246-1254.
-
(2000)
J Thorac Cardiovasc Surg
, vol.119
, pp. 1246-1254
-
-
Atkins, B.Z.1
Silvestry, S.C.2
Samy, R.N.3
Shah, A.S.4
Sabiston Jr., D.C.5
Glower, D.D.6
-
36
-
-
0036210058
-
Delayed cardioprotection induced by nitroglycerin is mediated by alpha-calcitonin gene-related peptide
-
Zhou ZH, Peng J, Ye F, Li NS, Deng HW, Li YJ,. Delayed cardioprotection induced by nitroglycerin is mediated by alpha-calcitonin gene-related peptide. Naunyn Schmiedebergs Arch Pharmacol. 2002; 365: 253-259.
-
(2002)
Naunyn Schmiedebergs Arch Pharmacol
, vol.365
, pp. 253-259
-
-
Zhou, Z.H.1
Peng, J.2
Ye, F.3
Li, N.S.4
Deng, H.W.5
Li, Y.J.6
-
37
-
-
77956233522
-
Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries
-
Chan KY, Edvinsson L, Eftekhari S, et al. Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries. J Pharmacol Exp Ther. 2010; 334: 746-752.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 746-752
-
-
Chan, K.Y.1
Edvinsson, L.2
Eftekhari, S.3
-
38
-
-
70350335038
-
Effects of the prototype serotonin 5-HT(1B/1D) receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP(8-37) on myocardial reactive hyperemic response in conscious dogs
-
Lynch JJ, Shen YT, Pittman TJ, et al. Effects of the prototype serotonin 5-HT(1B/1D) receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP(8-37) on myocardial reactive hyperemic response in conscious dogs. Eur J Pharmacol. 2009; 623: 96-102.
-
(2009)
Eur J Pharmacol
, vol.623
, pp. 96-102
-
-
Lynch, J.J.1
Shen, Y.T.2
Pittman, T.J.3
-
39
-
-
13244252481
-
The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers
-
Petersen KA, Birk S, Lassen LH, et al. The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers. Cephalalgia. 2005; 25: 139-147.
-
(2005)
Cephalalgia
, vol.25
, pp. 139-147
-
-
Petersen, K.A.1
Birk, S.2
Lassen, L.H.3
-
40
-
-
0036257940
-
BIBN4096BS is a potent competitive antagonist of the relaxant effects of alpha-CGRP on human temporal artery: Comparison with CGRP(8-37)
-
Verheggen R, Bumann K, Kaumann AJ,. BIBN4096BS is a potent competitive antagonist of the relaxant effects of alpha-CGRP on human temporal artery: Comparison with CGRP(8-37). Br J Pharmacol. 2002; 136: 120-126.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 120-126
-
-
Verheggen, R.1
Bumann, K.2
Kaumann, A.J.3
-
41
-
-
79953840319
-
The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men
-
Van der Schueren BJ, Blanchard R, Murphy MG, et al. The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men. Br J Clin Pharmacol. 2011; 71: 708-717.
-
(2011)
Br J Clin Pharmacol
, vol.71
, pp. 708-717
-
-
Van Der Schueren, B.J.1
Blanchard, R.2
Murphy, M.G.3
-
42
-
-
84857232404
-
A randomized, placebo-controlled study of the effects of telcagepant on exercise time in patients with stable angina
-
Chaitman BR, Ho AP, Behm MO, et al. A randomized, placebo-controlled study of the effects of telcagepant on exercise time in patients with stable angina. Clin Pharmacol Ther. 2012; 91: 459-466.
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 459-466
-
-
Chaitman, B.R.1
Ho, A.P.2
Behm, M.O.3
-
43
-
-
0022452273
-
Antagonism by some ergot derivatives of 5-HT-induced vasoconstriction
-
Conolan S, Taylor DA,. Antagonism by some ergot derivatives of 5-HT-induced vasoconstriction. Eur J Pharmacol. 1986; 123: 299-302.
-
(1986)
Eur J Pharmacol
, vol.123
, pp. 299-302
-
-
Conolan, S.1
Taylor, D.A.2
-
44
-
-
0005556702
-
Augmented contraction of the human isolated coronary artery by sumatriptan: A possible role for endogenous thromboxane
-
Maassen VanDenBrink A, Bax WA, Ferrari MD, Zijlstra FJ, Bos E, Saxena PR,. Augmented contraction of the human isolated coronary artery by sumatriptan: A possible role for endogenous thromboxane. Br J Pharmacol. 1996; 119: 855-862.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 855-862
-
-
Maassen Vandenbrink, A.1
Bax, W.A.2
Ferrari, M.D.3
Zijlstra, F.J.4
Bos, E.5
Saxena, P.R.6
-
45
-
-
0030905854
-
Comparison of the vasoconstrictor properties of the 5-HT1D-receptor agonists rizatriptan (MK-462) and sumatriptan in human isolated coronary artery: Outcome of two independent studies using different experimental protocols
-
Longmore J, Hargreaves RJ, Boulanger CM, et al. Comparison of the vasoconstrictor properties of the 5-HT1D-receptor agonists rizatriptan (MK-462) and sumatriptan in human isolated coronary artery: Outcome of two independent studies using different experimental protocols. Funct Neurol. 1997; 12: 3-9.
-
(1997)
Funct Neurol
, vol.12
, pp. 3-9
-
-
Longmore, J.1
Hargreaves, R.J.2
Boulanger, C.M.3
-
46
-
-
77956395079
-
Involvement of opioid receptors in the CGRP-induced antinociception in the nucleus accumbens of rats
-
Li L, Wang X, Yu LC,. Involvement of opioid receptors in the CGRP-induced antinociception in the nucleus accumbens of rats. Brain Res. 2010; 1353: 53-59.
-
(2010)
Brain Res
, vol.1353
, pp. 53-59
-
-
Li, L.1
Wang, X.2
Yu, L.C.3
-
47
-
-
0142043398
-
Involvement of calcitonin gene-related peptide and its receptor in anti-nociception in the periaqueductal grey of rats
-
Yu LC, Weng XH, Wang JW, Lundeberg T,. Involvement of calcitonin gene-related peptide and its receptor in anti-nociception in the periaqueductal grey of rats. Neurosci Lett. 2003; 349: 1-4.
-
(2003)
Neurosci Lett
, vol.349
, pp. 1-4
-
-
Yu, L.C.1
Weng, X.H.2
Wang, J.W.3
Lundeberg, T.4
-
48
-
-
80051500576
-
CGRP: Sensory neuropeptide with multiple neurologic implications
-
Benarroch EE,. CGRP: Sensory neuropeptide with multiple neurologic implications. Neurology. 2011; 77: 281-287.
-
(2011)
Neurology
, vol.77
, pp. 281-287
-
-
Benarroch, E.E.1
-
49
-
-
0028806454
-
Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat
-
Messlinger K, Hanesch U, Kurosawa M, Pawlak M, Schmidt RF,. Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat. Can J Physiol Pharmacol. 1995; 73: 1020-1024.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1020-1024
-
-
Messlinger, K.1
Hanesch, U.2
Kurosawa, M.3
Pawlak, M.4
Schmidt, R.F.5
-
50
-
-
0025819850
-
Immunohistochemical mapping of neurophysins and calcitonin gene-related peptide in the human brainstem and cervical spinal cord
-
Unger JW, Lange W,. Immunohistochemical mapping of neurophysins and calcitonin gene-related peptide in the human brainstem and cervical spinal cord. J Chem Neuroanat. 1991; 4: 299-309.
-
(1991)
J Chem Neuroanat
, vol.4
, pp. 299-309
-
-
Unger, J.W.1
Lange, W.2
-
51
-
-
40949083906
-
Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution
-
Lennerz JK, Ruhle V, Ceppa EP, et al. Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution. J Comp Neurol. 2008; 507: 1277-1299.
-
(2008)
J Comp Neurol
, vol.507
, pp. 1277-1299
-
-
Lennerz, J.K.1
Ruhle, V.2
Ceppa, E.P.3
-
52
-
-
84867096242
-
CGRP and NO in the trigeminal system: Mechanisms and role in headache generation
-
Messlinger K, Lennerz JK, Eberhardt M, Fischer MJ,. CGRP and NO in the trigeminal system: Mechanisms and role in headache generation. Headache. 2012; 52: 1411-1427.
-
(2012)
Headache
, vol.52
, pp. 1411-1427
-
-
Messlinger, K.1
Lennerz, J.K.2
Eberhardt, M.3
Fischer, M.J.4
-
53
-
-
78649940547
-
Possible sites of action of the new calcitonin gene-related peptide receptor antagonists
-
Eftekhari S, Edvinsson L,. Possible sites of action of the new calcitonin gene-related peptide receptor antagonists. Ther Adv Neurol Disord. 2010; 3: 369-378.
-
(2010)
Ther Adv Neurol Disord
, vol.3
, pp. 369-378
-
-
Eftekhari, S.1
Edvinsson, L.2
-
54
-
-
77950341045
-
Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: Findings from array analysis
-
Vause CV, Durham PL,. Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: Findings from array analysis. Neurosci Lett. 2010; 473: 163-167.
-
(2010)
Neurosci Lett
, vol.473
, pp. 163-167
-
-
Vause, C.V.1
Durham, P.L.2
-
55
-
-
79952417084
-
Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from wild-type and R192Q Cav2.1 Knock-in mice: Implications for basic mechanisms of migraine pain
-
Ceruti S, Villa G, Fumagalli M, et al. Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from wild-type and R192Q Cav2.1 Knock-in mice: Implications for basic mechanisms of migraine pain. J Neurosci. 2011; 31: 3638-3649.
-
(2011)
J Neurosci
, vol.31
, pp. 3638-3649
-
-
Ceruti, S.1
Villa, G.2
Fumagalli, M.3
-
56
-
-
77953461921
-
A potential preclinical migraine model: CGRP-sensitized mice
-
Russo AF, Kuburas A, Kaiser EA, Raddant AC, Recober A,. A potential preclinical migraine model: CGRP-sensitized mice. Mol Cell Pharmacol. 2009; 1: 264-270.
-
(2009)
Mol Cell Pharmacol
, vol.1
, pp. 264-270
-
-
Russo, A.F.1
Kuburas, A.2
Kaiser, E.A.3
Raddant, A.C.4
Recober, A.5
-
57
-
-
0024541247
-
The development of neurogenic plasma extravasation in the rat dura mater does not depend upon the degranulation of mast cells
-
Markowitz S, Saito K, Buzzi MG, Moskowitz MA,. The development of neurogenic plasma extravasation in the rat dura mater does not depend upon the degranulation of mast cells. Brain Res. 1989; 477: 157-165.
-
(1989)
Brain Res
, vol.477
, pp. 157-165
-
-
Markowitz, S.1
Saito, K.2
Buzzi, M.G.3
Moskowitz, M.A.4
-
58
-
-
81055126935
-
Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level
-
Eftekhari S, Edvinsson L,. Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level. BMC Neurosci. 2011; 12: 112.
-
(2011)
BMC Neurosci
, vol.12
, pp. 112
-
-
Eftekhari, S.1
Edvinsson, L.2
-
59
-
-
80054118085
-
Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse
-
Mathew R, Andreou AP, Chami L, et al. Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse. Cephalalgia. 2011; 31: 1368-1380.
-
(2011)
Cephalalgia
, vol.31
, pp. 1368-1380
-
-
Mathew, R.1
Andreou, A.P.2
Chami, L.3
-
60
-
-
0036260965
-
Neurovascular headache and a midbrain vascular malformation: Evidence for a role of the brainstem in chronic migraine
-
Goadsby PJ,. Neurovascular headache and a midbrain vascular malformation: Evidence for a role of the brainstem in chronic migraine. Cephalalgia. 2002; 22: 107-111.
-
(2002)
Cephalalgia
, vol.22
, pp. 107-111
-
-
Goadsby, P.J.1
-
61
-
-
0035978070
-
Brainstem activation specific to migraine headache
-
Bahra A, Matharu MS, Buchel C, Frackowiak RS, Goadsby PJ,. Brainstem activation specific to migraine headache. Lancet. 2001; 357: 1016-1017.
-
(2001)
Lancet
, vol.357
, pp. 1016-1017
-
-
Bahra, A.1
Matharu, M.S.2
Buchel, C.3
Frackowiak, R.S.4
Goadsby, P.J.5
-
62
-
-
0027619348
-
Neurogenic inflammation in the pathophysiology and treatment of migraine
-
Moskowitz MA,. Neurogenic inflammation in the pathophysiology and treatment of migraine. Neurology. 1993; 43 (6 Suppl. 3): S16-S20.
-
(1993)
Neurology
, vol.43
, Issue.6 SUPPL. 3
-
-
Moskowitz, M.A.1
-
63
-
-
0035340714
-
Neurogenic inflammation in the context of migraine
-
Williamson DJ, Hargreaves RJ,. Neurogenic inflammation in the context of migraine. Microsc Res Tech. 2001; 53: 167-178.
-
(2001)
Microsc Res Tech
, vol.53
, pp. 167-178
-
-
Williamson, D.J.1
Hargreaves, R.J.2
-
64
-
-
0037823484
-
The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin
-
Sun RQ, Lawand NB, Willis WD,. The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. Pain. 2003; 104: 201-208.
-
(2003)
Pain
, vol.104
, pp. 201-208
-
-
Sun, R.Q.1
Lawand, N.B.2
Willis, W.D.3
-
65
-
-
58649102662
-
Migraine in the triptan era: Lessons from epidemiology, pathophysiology, and clinical science
-
Bigal ME, Ferrari M, Silberstein SD, Lipton RB, Goadsby PJ,. Migraine in the triptan era: Lessons from epidemiology, pathophysiology, and clinical science. Headache. 2009; 49 (Suppl. 1): S21-S33.
-
(2009)
Headache
, vol.49
, Issue.SUPPL. 1
-
-
Bigal, M.E.1
Ferrari, M.2
Silberstein, S.D.3
Lipton, R.B.4
Goadsby, P.J.5
-
66
-
-
77957922955
-
CGRP and its receptors provide new insights into migraine pathophysiology
-
Ho TW, Edvinsson L, Goadsby PJ,. CGRP and its receptors provide new insights into migraine pathophysiology. Nat Rev Neurol. 2010; 6: 573-582.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 573-582
-
-
Ho, T.W.1
Edvinsson, L.2
Goadsby, P.J.3
-
67
-
-
0034648729
-
Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: An autoradiographic and immunohistochemical analysis
-
Morara S, Rosina A, Provini L, Forloni G, Caretti A, Wimalawansa SJ,. Calcitonin gene-related peptide receptor expression in the neurons and glia of developing rat cerebellum: An autoradiographic and immunohistochemical analysis. Neuroscience. 2000; 100: 381-391.
-
(2000)
Neuroscience
, vol.100
, pp. 381-391
-
-
Morara, S.1
Rosina, A.2
Provini, L.3
Forloni, G.4
Caretti, A.5
Wimalawansa, S.J.6
-
68
-
-
0024806932
-
Age-related increase in CGRP binding site densities in rat cerebellum
-
Pagani F, Guidobono F, Netti C, Re F, Pecile A,. Age-related increase in CGRP binding site densities in rat cerebellum. Pharmacol Res. 1989; 21 (Suppl. 1): 105-106.
-
(1989)
Pharmacol Res
, vol.21
, Issue.SUPPL. 1
, pp. 105-106
-
-
Pagani, F.1
Guidobono, F.2
Netti, C.3
Re, F.4
Pecile, A.5
-
69
-
-
79955628948
-
Advances in understanding the mechanisms of migraine-type photophobia
-
Noseda R, Burstein R,. Advances in understanding the mechanisms of migraine-type photophobia. Curr Opin Neurol. 2011; 24: 197-202.
-
(2011)
Curr Opin Neurol
, vol.24
, pp. 197-202
-
-
Noseda, R.1
Burstein, R.2
-
70
-
-
67650502716
-
Role of calcitonin gene-related peptide in light-aversive behavior: Implications for migraine
-
Recober A, Kuburas A, Zhang Z, Wemmie JA, Anderson MG, Russo AF,. Role of calcitonin gene-related peptide in light-aversive behavior: Implications for migraine. J Neurosci. 2009; 29: 8798-8804.
-
(2009)
J Neurosci
, vol.29
, pp. 8798-8804
-
-
Recober, A.1
Kuburas, A.2
Zhang, Z.3
Wemmie, J.A.4
Anderson, M.G.5
Russo, A.F.6
-
71
-
-
0028793376
-
Plasticity of calcitonin gene related peptide neurotransmission in the spinal cord during peripheral inflammation
-
Seybold VS, Galeazza MT, Garry MG, Hargreaves KM,. Plasticity of calcitonin gene related peptide neurotransmission in the spinal cord during peripheral inflammation. Can J Physiol Pharmacol. 1995; 73: 1007-1014.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1007-1014
-
-
Seybold, V.S.1
Galeazza, M.T.2
Garry, M.G.3
Hargreaves, K.M.4
-
72
-
-
33749636105
-
Pain-related synaptic plasticity in spinal dorsal horn neurons: Role of CGRP
-
Bird GC, Han JS, Fu Y, Adwanikar H, Willis WD, Neugebauer V,. Pain-related synaptic plasticity in spinal dorsal horn neurons: Role of CGRP. Mol Pain. 2006; 2: 31.
-
(2006)
Mol Pain
, vol.2
, pp. 31
-
-
Bird, G.C.1
Han, J.S.2
Fu, Y.3
Adwanikar, H.4
Willis, W.D.5
Neugebauer, V.6
-
73
-
-
0028969303
-
Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation
-
Galeazza MT, Garry MG, Yost HJ, Strait KA, Hargreaves KM, Seybold VS,. Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. Neuroscience. 1995; 66: 443-458.
-
(1995)
Neuroscience
, vol.66
, pp. 443-458
-
-
Galeazza, M.T.1
Garry, M.G.2
Yost, H.J.3
Strait, K.A.4
Hargreaves, K.M.5
Seybold, V.S.6
-
74
-
-
77956648239
-
The cerebellum and pain: Passive integrator or active participator?
-
Moulton EA, Schmahmann JD, Becerra L, Borsook D,. The cerebellum and pain: Passive integrator or active participator? Brain Res Rev. 2010; 65: 14-27.
-
(2010)
Brain Res Rev
, vol.65
, pp. 14-27
-
-
Moulton, E.A.1
Schmahmann, J.D.2
Becerra, L.3
Borsook, D.4
-
75
-
-
24344486827
-
Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study
-
Kruit MC, Launer LJ, Ferrari MD, van Buchem MA,. Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study. Brain. 2005; 128 (Pt 9): 2068-2077.
-
(2005)
Brain
, vol.128
, Issue.PART 9
, pp. 2068-2077
-
-
Kruit, M.C.1
Launer, L.J.2
Ferrari, M.D.3
Van Buchem, M.A.4
-
76
-
-
1542365240
-
Migraine as a risk factor for subclinical brain lesions
-
Kruit MC, van Buchem MA, Hofman PA, et al. Migraine as a risk factor for subclinical brain lesions. JAMA. 2004; 291: 427-434.
-
(2004)
JAMA
, vol.291
, pp. 427-434
-
-
Kruit, M.C.1
Van Buchem, M.A.2
Hofman, P.A.3
-
77
-
-
1542346238
-
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
-
Olesen J, Diener HC, Husstedt IW, et al. Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med. 2004; 350: 1104-1110.
-
(2004)
N Engl J Med
, vol.350
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.C.2
Husstedt, I.W.3
-
78
-
-
42249087655
-
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
-
Ho TW, Mannix LK, Fan X, et al. Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine. Neurology. 2008; 70: 1304-1312.
-
(2008)
Neurology
, vol.70
, pp. 1304-1312
-
-
Ho, T.W.1
Mannix, L.K.2
Fan, X.3
-
79
-
-
57649233374
-
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: A randomised, placebo-controlled, parallel-treatment trial
-
Ho TW, Ferrari MD, Dodick DW, et al. Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: A randomised, placebo-controlled, parallel-treatment trial. Lancet. 2008; 372: 2115-2123.
-
(2008)
Lancet
, vol.372
, pp. 2115-2123
-
-
Ho, T.W.1
Ferrari, M.D.2
Dodick, D.W.3
-
80
-
-
84857633644
-
New agents for acute treatment of migraine: CGRP receptor antagonists, iNOS inhibitors
-
Hoffmann J, Goadsby PJ,. New agents for acute treatment of migraine: CGRP receptor antagonists, iNOS inhibitors. Curr Treat Options Neurol. 2012; 14: 50-59.
-
(2012)
Curr Treat Options Neurol
, vol.14
, pp. 50-59
-
-
Hoffmann, J.1
Goadsby, P.J.2
-
81
-
-
77949687406
-
Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist
-
Salvatore CA, Moore EL, Calamari A, et al. Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist. J Pharmacol Exp Ther. 2010; 333: 152-160.
-
(2010)
J Pharmacol Exp Ther
, vol.333
, pp. 152-160
-
-
Salvatore, C.A.1
Moore, E.L.2
Calamari, A.3
-
82
-
-
79954607744
-
Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine
-
Hewitt DJ, Aurora SK, Dodick DW, et al. Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine. Cephalalgia. 2011; 31: 712-722.
-
(2011)
Cephalalgia
, vol.31
, pp. 712-722
-
-
Hewitt, D.J.1
Aurora, S.K.2
Dodick, D.W.3
-
84
-
-
79953220801
-
BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: Results from a phase II study
-
Diener HC, Barbanti P, Dahlof C, Reuter U, Habeck J, Podhorna J,. BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: Results from a phase II study. Cephalalgia. 2011; 31: 573-584.
-
(2011)
Cephalalgia
, vol.31
, pp. 573-584
-
-
Diener, H.C.1
Barbanti, P.2
Dahlof, C.3
Reuter, U.4
Habeck, J.5
Podhorna, J.6
-
85
-
-
78650925201
-
Long-term tolerability of telcagepant for acute treatment of migraine in a randomized trial
-
Connor KM, Aurora SK, Loeys T, et al. Long-term tolerability of telcagepant for acute treatment of migraine in a randomized trial. Headache. 2011; 51: 73-84.
-
(2011)
Headache
, vol.51
, pp. 73-84
-
-
Connor, K.M.1
Aurora, S.K.2
Loeys, T.3
-
88
-
-
0020031557
-
Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody
-
Miller RA, Maloney DG, Warnke R, Levy R,. Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N Engl J Med. 1982; 306: 517-522.
-
(1982)
N Engl J Med
, vol.306
, pp. 517-522
-
-
Miller, R.A.1
Maloney, D.G.2
Warnke, R.3
Levy, R.4
-
89
-
-
33947304452
-
The pharmacokinetics and pharmacodynamics of monoclonal antibodies-mechanistic modeling applied to drug development
-
Mould DR, Sweeney KR,. The pharmacokinetics and pharmacodynamics of monoclonal antibodies-mechanistic modeling applied to drug development. Curr Opin Drug Discov Devel. 2007; 10: 84-96.
-
(2007)
Curr Opin Drug Discov Devel
, vol.10
, pp. 84-96
-
-
Mould, D.R.1
Sweeney, K.R.2
-
90
-
-
77953658260
-
The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions
-
Harding FA, Stickler MM, Razo J, DuBridge RB,. The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions. Mabs. 2010; 2: 256-265.
-
(2010)
Mabs
, vol.2
, pp. 256-265
-
-
Harding, F.A.1
Stickler, M.M.2
Razo, J.3
Dubridge, R.B.4
-
91
-
-
17644415682
-
Design of humanized antibodies: From anti-Tac to Zenapax
-
Tsurushita N, Hinton PR, Kumar S,. Design of humanized antibodies: From anti-Tac to Zenapax. Methods. 2005; 36: 69-83.
-
(2005)
Methods
, vol.36
, pp. 69-83
-
-
Tsurushita, N.1
Hinton, P.R.2
Kumar, S.3
-
92
-
-
17644378667
-
Immunogenicity of engineered antibodies
-
Hwang WY, Foote J,. Immunogenicity of engineered antibodies. Methods. 2005; 36: 3-10.
-
(2005)
Methods
, vol.36
, pp. 3-10
-
-
Hwang, W.Y.1
Foote, J.2
-
93
-
-
17644413164
-
Humanized antibodies and their applications
-
Wu H, Dall'Acqua WF,. Humanized antibodies and their applications. Methods. 2005; 36: 1-2.
-
(2005)
Methods
, vol.36
, pp. 1-2
-
-
Wu, H.1
Dall'Acqua, W.F.2
-
94
-
-
84884169110
-
-
Services USDoHaH, Administration FaD, (CDER) CfDEaR, (CBER) CfBEaR. Guidance for industry (accessed April 24, 2013)
-
Services USDoHaH, Administration FaD, (CDER) CfDEaR, (CBER) CfBEaR. Guidance for industry. M3(R2) nonclinical safety studies for the conduct of human clinical trials and marketing authorization for pharmaceuticals. 1994. Available at: http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/ucm073246.pdf (accessed April 24, 2013).
-
(1994)
M3(R2) Nonclinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals
-
-
-
95
-
-
33644865904
-
Early development of therapeutic biologics-pharmacokinetics
-
Baumann A,. Early development of therapeutic biologics-pharmacokinetics. Curr Drug Metab. 2006; 7: 15-21.
-
(2006)
Curr Drug Metab
, vol.7
, pp. 15-21
-
-
Baumann, A.1
-
96
-
-
71749086384
-
General toxicity testing and immunotoxicity testing for biopharmaceuticals
-
Cavagnaro J.A. ed. New York: Wiley.
-
Bussiere JL,. General toxicity testing and immunotoxicity testing for biopharmaceuticals. In:, Cavagnaro JA, ed. Preclinical Safety Evaluation of Biopharmaceuticals. New York: Wiley; 2008: 125-155.
-
(2008)
Preclinical Safety Evaluation of Biopharmaceuticals
, pp. 125-155
-
-
Bussiere, J.L.1
-
97
-
-
0009756580
-
-
Services UDoHaH, Administration FaD, (CDER) CfDEaR, (CBER) CfBEaR (accessed April 20, 2013)
-
Services UDoHaH, Administration FaD, (CDER) CfDEaR, (CBER) CfBEaR. Guidance for industry, S6 Preclinical safety evaluation of biotechnology-derived pharmaceuticals, 1997. Available at: http://www.fda.gov/downloads/ regulatoryinformation/guidances/ucm129171.pdf (accessed April 20, 2013).
-
(1997)
Guidance for Industry, S6 Preclinical Safety Evaluation of Biotechnology-derived Pharmaceuticals
-
-
-
98
-
-
48149092512
-
Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics
-
Vargas HM, Bass AS, Breidenbach A, et al. Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics. J Pharmacol Toxicol Methods. 2008; 58: 72-76.
-
(2008)
J Pharmacol Toxicol Methods
, vol.58
, pp. 72-76
-
-
Vargas, H.M.1
Bass, A.S.2
Breidenbach, A.3
-
99
-
-
84884129615
-
-
clinicaltrial.gov (accessed April 10, 2013)
-
clinicaltrial.gov. A study of LY2951742 in healthy volunteers. 2013. Available at: http://www.clinicaltrials.gov/ct2/show/NCT01337596?term= LY2951742&rank=1 (accessed April 10, 2013).
-
(2013)
A Study of LY2951742 in Healthy Volunteers
-
-
-
100
-
-
84884130378
-
-
(accessed April 10, 2013)
-
A study of LY2951742 in patients with migraine. 2013. Available at: http://www.clinicaltrials.gov/ct2/show/NCT01625988?term=LY2951742&rank=2 (accessed April 10, 2013).
-
(2013)
A Study of LY2951742 in Patients with Migraine
-
-
-
101
-
-
84884156109
-
-
(accessed April 10, 2013)
-
Safety, efficacy and pharmacokinetics of ALD403. 2013. Available at: http://clinicaltrials.gov/ct2/show/NCT01772524?term=ald403&rank=2 (accessed April 10, 2013).
-
(2013)
Safety, Efficacy and Pharmacokinetics of ALD403
-
-
-
102
-
-
84884130338
-
-
(accessed April 10, 2013)
-
Amgen-science-pipeline. 2013. Available at: http://www.amgen.com/science/ pipe.html (accessed April 10, 2013).
-
(2013)
Amgen - Science Pipeline
-
-
-
106
-
-
77957723606
-
Rates and predictors of starting a triptan: Results from the american migraine prevalence and prevention study
-
Bigal ME, Buse DC, Chen YT, et al. Rates and predictors of starting a triptan: Results from the american migraine prevalence and prevention study. Headache. 2010; 50: 1440-1448.
-
(2010)
Headache
, vol.50
, pp. 1440-1448
-
-
Bigal, M.E.1
Buse, D.C.2
Chen, Y.T.3
-
107
-
-
67650317926
-
The acute treatment of episodic and chronic migraine in the USA
-
Bigal ME, Borucho S, Serrano D, Lipton RB,. The acute treatment of episodic and chronic migraine in the USA. Cephalalgia. 2009; 29: 891-897.
-
(2009)
Cephalalgia
, vol.29
, pp. 891-897
-
-
Bigal, M.E.1
Borucho, S.2
Serrano, D.3
Lipton, R.B.4
-
108
-
-
0036780166
-
Triptans (serotonin, 5-HT1B/1D agonists) in migraine: Detailed results and methods of a meta-analysis of 53 trials
-
Ferrari MD, Goadsby PJ, Roon KI, Lipton RB,. Triptans (serotonin, 5-HT1B/1D agonists) in migraine: Detailed results and methods of a meta-analysis of 53 trials. Cephalalgia. 2002; 22: 633-658.
-
(2002)
Cephalalgia
, vol.22
, pp. 633-658
-
-
Ferrari, M.D.1
Goadsby, P.J.2
Roon, K.I.3
Lipton, R.B.4
-
109
-
-
51549110159
-
Acute migraine medications and evolution from episodic to chronic migraine: A longitudinal population-based study
-
Bigal ME, Serrano D, Buse D, Scher A, Stewart WF, Lipton RB,. Acute migraine medications and evolution from episodic to chronic migraine: A longitudinal population-based study. Headache. 2008; 48: 1157-1168.
-
(2008)
Headache
, vol.48
, pp. 1157-1168
-
-
Bigal, M.E.1
Serrano, D.2
Buse, D.3
Scher, A.4
Stewart, W.F.5
Lipton, R.B.6
-
110
-
-
77649123795
-
Migraine and cardiovascular disease: A population-based study
-
Bigal ME, Kurth T, Santanello N, et al. Migraine and cardiovascular disease: A population-based study. Neurology. 2010; 74: 628-635.
-
(2010)
Neurology
, vol.74
, pp. 628-635
-
-
Bigal, M.E.1
Kurth, T.2
Santanello, N.3
-
111
-
-
33846576913
-
Migraine prevalence, disease burden, and the need for preventive therapy
-
Lipton RB, Bigal ME, Diamond M, et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology. 2007; 68: 343-349.
-
(2007)
Neurology
, vol.68
, pp. 343-349
-
-
Lipton, R.B.1
Bigal, M.E.2
Diamond, M.3
-
112
-
-
33644873543
-
Removing barriers to appropriate migraine treatment: Formulary limitations and triptan package size
-
Silberstein SD, Dodick D, Kesslick J,. Removing barriers to appropriate migraine treatment: Formulary limitations and triptan package size. Headache. 2005; 45: 1250-1254.
-
(2005)
Headache
, vol.45
, pp. 1250-1254
-
-
Silberstein, S.D.1
Dodick, D.2
Kesslick, J.3
-
113
-
-
82955236200
-
OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine
-
Lipton RB, Varon SF, Grosberg B, et al. OnabotulinumtoxinA improves quality of life and reduces impact of chronic migraine. Neurology. 2011; 77: 1465-1472.
-
(2011)
Neurology
, vol.77
, pp. 1465-1472
-
-
Lipton, R.B.1
Varon, S.F.2
Grosberg, B.3
-
114
-
-
84872114189
-
A rational approach to the management of chronic migraine
-
Evans RW,. A rational approach to the management of chronic migraine. Headache. 2013; 53: 168-176.
-
(2013)
Headache
, vol.53
, pp. 168-176
-
-
Evans, R.W.1
-
115
-
-
70349682469
-
Randomized, controlled trial of telcagepant for the acute treatment of migraine
-
Connor KM, Shapiro RE, Diener HC, et al. Randomized, controlled trial of telcagepant for the acute treatment of migraine. Neurology. 2009; 73: 970-977.
-
(2009)
Neurology
, vol.73
, pp. 970-977
-
-
Connor, K.M.1
Shapiro, R.E.2
Diener, H.C.3
|