Calcitonin gene-related peptide in myocardial ischaemia and reperfusion in the pig

Cardiovascular Research

Volumn 38, Issue 2, 1998, Pages 493-499

  Källner, Göran ^a   Gonon, Adrian ^a   Franco Cereceda, Anders ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

C fiber; CGRP; CGRP(8 37); Ischemia; Pig; Reperfusion

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE[8-37]; TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY OBSTRUCTION; FEMALE; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE DP-DT; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART RATE; HYPEREMIA; HYPOTENSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MEAN ARTERIAL PRESSURE; NERVE FIBER C; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; BLOOD PRESSURE; CALCITONIN GENE-RELATED PEPTIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART RATE; MALE; MIOTICS; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PEPTIDE FRAGMENTS; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; SWINE;

EID: 0032076264     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00016-9     Document Type: Article

References (31)

1. [1] Meller ST, Gebhart GF. Silent ischemia: a hypothetical mechanism. Neurosci Biobehav Rev 1993;17(2):229-236.
2. [2] Szallasi A. The vanilloid (capsaicin) receptor: receptor types and species differences. Gen Pharmacol 1994;25(2):223-243.
3. [3] Bevan S, Szolcsanyi J. Sensory neuron-specific actions of capsaicin: mechanisms and applications. Trends Pharmacol Sci 1990;11:330-333.
4. [4] Franco-Cereceda A. Calcitonin gene-related peptide and tachykinins in relation to local sensory control of cardiac contractility and coronary vascular tone. Acta Physiol Scand 1988;133(Suppl. 569):1-63.
5. [5] Franco-Cereceda A. Calcitonin gene-related peptide and human epicardial coronary arteries: presence, release and vasodilator effects. Br J Pharmacol 1991;102:506-510.
6. [6] Franco-Cereceda A, Källner G, Lundberg JM. Capsazepine-sensitive release of calcitonin gene-related peptide from C-fibre afferents in the guinea-pig heart by low pH and lactic acid. Eur J Pharmacol 1993;238:311-316.
7. [7] Ichihara K, Morimoto T, Shiba T, Tsujitani M, Abiko Y. Attenuation of ischaemia-induced regional myocardial acidosis by LP-805, a newly developed vasodilator, in dogs. Eur J Pharmacol 1991;204:127-133.
8. [8] Geppetti P, Tramontana M, Patacchini R, et al. Neurochemical evidence for the activation of the 'efferent' function of capsaicin-sensitive nerves by lowering of the pH in the guinea-pig urinary bladder. Neurosci Lett 1990;114:101-106.
9. [9] Geppetti, Tramontana M, Evangelista S, et al. Differential effect on neuropeptide release of different concentrations of hydrogen ions on afferent and intrinsic neurones of the rat stomach. Gastroenterology 1991;101:1505-1511.
10. [10] Preibisz JJ. Calcitonin gene-related peptide and regulation of human cardiovascular homeostasis. Am J Hypertens 1993;6:434-450.
11. [11] D'Alonzo AJ, Grover GJ, Darbenzio RB, Hess TA, et al. In vitro effects of capsaicin: antiarrhythmic and antiischemic activity. Eur J Pharmacol 1995;272:269-278.
12. [12] Li Y-J, Xiao Z-S, Peng C-F, Deng H-W. Calcitonin gene-related peptide-induced preconditioning protects against ischemia-reperfusion injury in isolated rat hearts. Eur J Pharmacol 1996;311:163-167.
13. [13] Franco-Cereceda A, Rudehill A, Lundberg JM. Calcitonin gene-related peptide but not substance P mimics capsaicin induced coronary vasodilation in the pig. Eur J Pharmacol 1987;142:235-243.
14. [14] Rydén L, Tadokoro H, Sjoquist P-O, et al. Pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion. J Cardiovasc Pharmacol 1990;15:22-28.
15. [15] Rydén L, Tadokoro H, Sjoquist P-O, et al. Pharmacokinetic analysis of coronary venous retroinfusion: A comparison with antegrade coronary artery drug administration using metoprolol as a tracer. J Am Coll Cardiol 1991;18:603-612.
16. [16] Fishbein MC, Meerbaum S, Rit J, et al. Early phase acute myocardial infarct size quantification: validation of the triphenyl tetrazolium chloride tissue enzyme staining technique. Am Heart J 1981;101:593-600.
17. [17] Holmbom B, Näslund U, Eriksson A, Virtanen I, Thornell L-E. Comparison of triphenyltetrazolium (TTC) staining versus fibronectin in experimental myocardial infarction. Histochemistry 1993;99:265-275.
18. [18] Eckstein RW. Coronary interarterial anatomoses in young pigs and mongrel dogs. Circ Res 1954;2:460-465.
19. [19] Maxwell MP, Hearse DJ, Yellon DM. Species variation in the coronary collateral circulation during regional myocardial ischaemia: a critical determinant of the rate of evolution and extent of myocardial infarction. Cardiovasc Res 1987;21:737-746.
20. [20] Näslund U, Häggmark S, Johansson G, Marklund SL, Reiz S. Limitation of myocardial infarct size by superoxide dismutase as an adjunct to reperfusion after different durations of coronary occlusion in the pig. Circ Res 1990;66:1294-1301.
21. [21] Sekiguchi N, Kanatsuka H, Sato K, et al. Effect of calcitonin gene-related peptide on coronary microvessels and its role in acute myocardial ischemia. Circulation 1994;89:366-374.
22. [22] Ezra D, Laurindo FRM, Goldstein DS, Goldstein RE, Feuerstein G. Calcitonin gene-related peptide: a potent modulator of coronary flow. Eur J Pharmacol 1987;137:101-105.
23. [23] Franco-Cereceda A. Resiniferatoxin-, capsaicin-, and CGRP-evoked porcine coronary vasodilation is independent of EDRF mechanisms but antagonized by CGRP(8-37). Acta Physiol Scand 1991;143:331-337.
24. [24] Thorén PN. Activation of left ventricular receptors with nonmedullated vagal afferent fibers during occlusion of a coronary artery in the cat. Am J Cardiol 1976;37:1046-1051.
25. [25] Ambrosio G, Weisman HF, Mansini JA, Becker JC. Progressive impairment of regional myocardial perfusion after initial restoration of postischemic blood flow. Circulation 1989;80:1846-1861.
26. [26] Hansen PR. Myocardial reperfusion injury: experimental evidence and clinical relevance. Eur Heart J 1995;16:734-740.
27. [27] Wang Q-D, Li X-S, Lundberg JM, Pernow J. Protective effect of non-peptide endothelin receptor antagonist bosentan on myocardial ischemic and reperfusion injury in the pig. Cardiovasc Res 1995;29:805-812.
28. [28] Kobayashi S, Tadokoro H, Rydén L, et al. Local beta-adrenergic blockade does not reduce infarct size after coronary occlusion and reperfusion: a study of coronary venous retroinfusion of metoprolol. Cardiovasc Drugs Ther 1993;7:159-167.
29. [29] Hearse DJ. Activation of ATP-sensitive potassium channels: a novel pharmacological approach to myocardial protection?. Cardiovasc Res 1995;30:1-17.
30. [30] Parratt JR. Protection of the heart by ischemic preconditioning: mechanisms and possibilities for pharmacological exploitation. Trends Pharmacol Sci 1994;15:19-25.
31. [31] Lu E-X, Peng C-F, Li Y-J, Cheng S-X. Calcitonin gene-related peptide-induced preconditioning improves preservation with cardioplegia. Ann Thorac Surg 1996;62:1748-1751.