Augmented contraction of the human isolated coronary artery by sumatriptan: A possible role for endogenous thromboxane

British Journal of Pharmacology

Volumn 119, Issue 5, 1996, Pages 855-862

  Van Den Brink, Antoinette Maassen ^a   Bax, Willem A ^a   Ferrari, Michel D ^b   Zijlstra, Freek J ^a   Bos, Egbert ^a   Saxena, Pramod R ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

5 HT(1D) receptor; Aspirin; Endothelin 1; Human coronary artery; Migraine; Sumatriptan; Thromboxane A2

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; 7 [3 [(2 HEPTANAMIDOACETAMIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ACETYLSALICYLIC ACID; ANTIMIGRAINE AGENT; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; SUMATRIPTAN; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; DRUG MECHANISM; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

EID: 0005556702     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15751.x     Document Type: Article

References (36)

1. BAX, W.A., RENZENBRINK, G.J., VAN HEUVEN-NOLSEN, D., THIJSSEN, H.J.M., BOS, E. & SAXENA, P.R. (1993). 5-HT receptors mediating contractions of the isolated human coronary artery. Eur. J. Pharmacol., 239, 203-210.
2. BAX, W.A., RENZENBRINK, G.J., VAN DER LINDEN, E.A., ZIJESTRA, F.J., VAN HEUVEN-NOLSEN, D., EEKKES, D., BOS, E. & SAXENA. P.R. (1994). Low-dose aspirin inhibits platelet-induced contraction of the human isolated coronary artery; a role for additional 5-HT receptor antagonism against coronary vasospasm? Circulation, 89, 623-629.
3. BROWN, E.G., ENDERSBY, C.A., SMITH, R.N. & TALBOT, J.C.C. (1991). The safety and tolerability of sumatriptan: an overview. Eur. Neurol., 31, 339-344.
4. 2 and 5-hydroxytryptamine receptor subtypes in human coronary arteries. Circulation, 87, 874-880.
5. CHESTER, A.H., MARTIN, G.R., BODElSSON, M., ARNEKLONOBIN, B., TADJKARIMI, S., TORNEBRANDT, K. & YACOUB, M.H. (1990). 5-Hydroxytryptamine receptor profile in healthy and diseased human epicardial coronary arteries. Cardiovasc. Res., 24, 932-937.
6. CHESTER, A.M., O'NEIL, G.S., ALLEN, S.P., LUU, T.N., TADJKARIMI, S. & YACOUB, M.H. (1992). Effect of endothelin on normal and diseased human coronary arteries. Eur. J. Cliin. Invest., 22, 210-213.
7. CHESTER, A.H., O'NEIL, G.S & YACOUB, M.H. (1993b). Sumatriptan and isehaemic heart disease. Lancet, 341, 1419-1420.
8. 2-receptor agonist, U46619. Br. J. Pharmacol., 110, 360-368.
9. 2 receptor activation. Eur. J. Pharmacol., 161, 91-94.
10. DE BOER, A.C., TURPIE, A.G.G., BUTT, R.W., JOHNSTON, R.V. & GENTON, E. (1982). Platelet release and thromboxane synthesis in symptomatic coronary artery disease. Circulation, 66, 327-333.
11. DE LEAN, A., MUNSON, P.J. & RODBARD, D. (1978). Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am. J. Physiol., 235, E97-E102.
12. FERRARI, M.D. & SAXENA, P.R. (1993). Clinical and experimental effects of sumatriptan in humans. Trends Pharmacol. Sci., 14, 129-133.
13. HOUGHTON, L.A., FOSTER, J.M., WHORWELL, P.J., MORRIS, J. & FOWLER, P. (1994). Is chest pain after sumatriptan oesophageal in origin? Lancet, 344, 985-986.
14. 1-like receptor in dog isolated saphenous vein. Br. J. Pharmacol., 94, 1123-1132.
15. 1Dβ receptors. Circulation, 90, 1141-1153.
16. 2: an endothelium-derived vasoconstrictor in human internal mammary arteries. Ann. Thorac. Surg., 56, 97-100.
17. 1-receptor agonist on central hemodynamics and the coronary circulation. Br. J. Clin. Pharmacol., 34, 541-546.
18. MACLENNAN, S.J., BOLOFO, M.L. & MARTIN, G.R. (1993). Amplifying interactions between spasmogens in vascular smooth muscle. Biochem. Soc. Trans., 21, 1145-1150.
19. 2 receptor mediated contraction of the rabbit isolated femoral artery. Br. J. Pharmacol., 107, 418-421.
20. 2 production by human arteries and veins. Prostaglandins. 25, 753-767.
21. 2-receptor antagonist in vitro. Pharmacologist. 28, 186.
22. OHLSTHIN, H.H., BECK, G.R., Jr., DOUGLAS, S.A., NAMBI, P., LAGO, M.A., GLEASON, J.G., RUFFHOLO, JR, R.R., FEUERSTEIN, G. & ELLIOTT, J.D. (1994). Nonpeptide endothelin receptor antagonists. II. Pharmacological characterization of SB 209670. J. Pharmacol. Exp. Ther., 271, 762-768.
23. OTTERVANGER, J.P. (1996). Pharmaco-epidemiology of sumatriptan. Cardiovascular adverse reactions to a new antimigrainous drug. Thesis, Erasmus University Rotterdam.
24. PLOSKER, G.L. & MCTAVISH, D. (1994). Sumatriptan. A reappraisal of its pharmacology and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs, 47, 622-651.
25. RUBANYI, G.M., FRYE, R.L., HOLMES, D.R, & VANHOUTTE, P.M. (1987). Vasoconstrictor activity of coronary sinus plasma from patients with coronary artery disease. J. Am. Coll. Cardiol., 9, 1243-1249.
26. 1-like receptors mediate 5-hydroxytryptamine-induced contraction of guinea-pig isolated iliac artery. Br. J. Pharmacol., 102, 386-390.
27. SAXENA, P.R. & TFELT-HANSEN, P. (1993). Sumatriptan. In The Headaches, ed. Olesen, J., Tfelt-Hansen, P. & Welch, K.M.A. pp. 329-341. New York: Raven Press, Ltd.
28. x. Pharmacol. Rev., 9, 242-246.
29. STEEL, R.G.D. & TORRIE, J.H. (1980). Principles and Procedures of Statistics. A Biomedical Approach. 2nd. edn., Tokyo: McGraw-Hill Kogakusha Ltd.
30. 2 levels in patients with classic and variant angina pectoris. Circulation, 64, 1107-1115.
31. TADIPATRI, S., VAN HEUVEN-NOLSEN, D., FENIUK, W. & SAXENA, P.R. (1991). Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery. Br. J. Pharmacol., 104, 887-894.
32. 2 in the saliva of common migraine patients. Action of calcium channel blockers. Headache, 29, 498-501.
33. WILLET, F., CURZEN, N., ADAMS, J. & ARMITAGE, M. (1992). Coronary vasospasm induced by subcutaneous sumatriptan. Br. Med. J., 304, 1415.
34. YANG, Z., RICHARD, V., VON SEGESSER, L., BAUER, E., STULZ, P., TURINA, M. & LÜSCHER, T.F. (1990). Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries; a new mechanism of vasospasm? Circulation. 82, 188-195.
35. YILDIZ, O. & TUNCER, M. (1995). Amplification of responses to sumatriptan by various agonists in rabbit isolated iliac artery. J. Cardiovasc. Pharmacol., 25, 508-510.
36. 14C]arachidonic acid labelled human lung tissue by high-performance liquid chromatography and radioimmunoassay. J. Chronatography, 311, 39-50.