Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  McGilligan, Victoria E ^a,b   Gregory Ksander, Meredith S ^a   Li, Dayu ^a   Moore, Jonathan E ^b,c   Hodges, Robin R ^a   Gilmore, Michael S ^d   Moore, Tara C B ^b   Dartt, Darlene A ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ULSTER   (United Kingdom)

^c Cathedral Eye Clinic   (United Kingdom)

^d MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; CASPASE INHIBITOR; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; STAPHYLOCOCCUS TOXIN; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONJUNCTIVITIS; CONTROLLED STUDY; CYTOKINE RELEASE; GOBLET CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INNATE IMMUNITY; MALE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STAPHYLOCOCCUS AUREUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 1; CONJUNCTIVA; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; GOBLET CELLS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MALE; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, PURINERGIC P2X4; RECEPTORS, PURINERGIC P2X7; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2;

EID: 84883828991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074010     Document Type: Article

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