Antibacterial activity and mechanism of action of ε-poly-l-lysine

Biochemical and Biophysical Research Communications

Volumn 439, Issue 1, 2013, Pages 148-153

  Ye, Ruosong ^a   Xu, Hengyi ^a   Wan, Cuixiang ^a   Peng, Shanshan ^a   Wang, Lijun ^a   Xu, Hong ^b   Aguilar, Zoraida P ^b   Xiong, Yonghua ^a   Zeng, Zheling ^a   Wei, Hua ^a  

^a NANCHANG UNIVERSITY   (China)

^b OCEAN NANOTECH LLC   (United States)

Author keywords

Poly l lysine; Antibacterial mechanism; Escherichia coli O157:H7; Reactive oxygen species; Real time quantitative PCR

Indexed keywords

ACETYLCYSTEINE; ANTIINFECTIVE AGENT; ANTIOXIDANT; EPSILON POLY LEVO LYSINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIAL GENE; BACTERIAL VIRULENCE; CELL STRUCTURE; DNA DAMAGE; DNA REPAIR; DRUG MECHANISM; ESCHERICHIA COLI O157; GENE EXPRESSION; LYSIS; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

Ε-POLY-L-LYSINE; ANTIBACTERIAL MECHANISM; ESCHERICHIA COLI O157:H7; REACTIVE OXYGEN SPECIES; REAL-TIME QUANTITATIVE PCR;

ACETYLCYSTEINE; ANTI-BACTERIAL AGENTS; AZIDES; CELL MEMBRANE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI O157; FOOD CONTAMINATION; FOOD MICROBIOLOGY; GENE EXPRESSION REGULATION, BACTERIAL; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; OXIDATION-REDUCTION; OXIDATIVE STRESS; POLYLYSINE; PROPIDIUM; REACTIVE OXYGEN SPECIES;

ESCHERICHIA COLI;

EID: 84883749494     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.08.001     Document Type: Article

References (27)

1. Mead P.S., Slutsker L., Dietz V., McCaig L.F., Bresee J.S., Shapiro C., Griffin P.M., Tauxe R.V. Food-related illness and death in the United States. Emerg. Infect. Dis. 1999, 5:607-625.
2. Cleveland J., Montville T.J., Nes I.F., Chikindas M.L. Bacteriocins: safe, natural antimicrobials for food preservation. Int. J. Food Microbiol. 2001, 71:1-20.
3. Najjar M.B., Kashtanov D., Chikindas M. ε-Poly-l-lysine and nisin A act synergistically against Gram-positive food-borne pathogensBacillus cereus and Listeria monocytogenes. Lett. Appl. Microbiol. 2007, 45:13-18.
4. Geornaras I., Yoon Y., Belk K.E., Smith G.C., Sofos J.N. Antimicrobial activity of epsilon-polylysine against Escherichia coli O157:H7 Salmonella Typhimurium, and Listeria monocytogenes in various food extracts. Food microbiol. 2007, 72:M330-M334.
5. Yoshida T., Yoshida T. ε-Poly-l-lysine: microbial production, biodegradation and application potential. Appl. Microbiol. Biotechnol. 2003, 62:21-26.
6. Hiraki J., Ichikawa T., Ninomiya S., Seki H., Uohama K., Kimura S., Yanagimoto Y., Barnett J.W. Use of ADME studies to confirm the safety of epsilon-polylysine as a preservative in food. Regul. Toxicol. Pharmacol. 2003, 37:328-340.
7. Yu H., Huang Y., Huang Q. Synthesis and characterization of novel antimicrobial emulsifiers from ε-Polylysine. J. Agric. Food Chem. 2009, 58:1290-1295.
8. Shih I.L., Shen M.H., Van Y.T. Microbial synthesis of poly(epsilon-lysine) and its various applications. Bioresour. Technol. 2006, 97:1148-1159.
9. Nishikawa M., Ogawa K. Distribution of microbes producing antimicrobial ε-poly-l-lysine polymers in soil microflora determined by a novel method. Appl. Environ. Microbiol. 2002, 68:3575.
10. Chang S.S., Lu W.Y., Park S.H., Kang D.H. Control of foodborne pathogens on ready-to-eat roast beef slurry by epsilon-polylysine. Int. J. Food Microbiol. 2010, 141:236-241.
11. Shima S., Matsuoka H., Iwamoto T., Sakai H. Antimicrobial action of epsilon-poly-l-lysine. J. Antibiot. 1984, 37:1449-1455.
12. Yanez M.A., Nocker A., Soria-Soria E., Murtula R., Martinez L., Catalan V. Quantification of viable Legionella pneumophila cells using propidium monoazide combined with quantitative PCR. J. Microbiol. Methods 2011, 85:124-130.
13. Franz E., Klerks M.M., De Vos O.J., Termorshuizen A.J., van Bruggen A.H.C. Prevalence of Shiga toxin-producing Escherichia coli stx1, stx2, eaeA, and rfbE genes and survival of E. coli O157: H7 in manure from organic and low-input conventional dairy farms. Appl. Environ. Microbiol. 2007, 73:2180-2190.
14. Michan C., Manchado M., Dorado G., Pueyo C. In vivo transcription of the Escherichia coli oxyR regulon as a function of growth phase and in response to oxidative stress. J. Bacteriol. 1999, 181:2759-2764.
15. Carruthers M.D., Bellaire B.H., Minion F.C. Exploring the response of Escherichia coli O157: H7 EDL933 within Acanthamoeba castellanii by genome-wide transcriptional profiling. FEMS Microbiol. Lett. 2010, 312:15-23.
16. Kim J.H., Kim J.C., Choo Y.A., Jang H.C., Choi Y.H., Chung J.K., Cho S.H., Park M.S., Lee B.K. Detection of cytolethal distending toxin and othervirulence characteristics of enteropathogenic Escherichia coli isolates from diarrheal patients in Republic of Korea. J. Microbiol. Biotechnol. 2009, 19:525-529.
17. Xie Y., He Y., Irwin P.L., Jin T., Shi X. Antibacterial activity and mechanism of action of zinc oxide nanoparticles against Campylobacter jejuni. Appl. Environ. Microbiol. 2011, 77:2325-2331.
18. Frank T., Mbecko J.R., Misatou P., Monchy D. Emergence of quinolone resistance among extended-spectrum beta-lactamase-producingEnterobacteriaceae in the Central African Republic: genetic characterization. BMC Res. Notes 2011, 4:309.
19. Hiraki J. ε-Polylysine, its development and utilization. Fine Chem. 2000, 29:18-25.
20. Smirnova G.V., Samoylova Z.Y., Muzyka N.G., Oktyabrsky O.N. Influence of polyphenols on Escherichia coli resistance to oxidative stress. Free Radic. Biol. Med. 2009, 46:759-768.
21. Batinic-Haberle I., Rajic Z., Benov L. A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon. Anticancer Agents Med. Chem. 2011, 11:329-340.
22. Shimoni Y., Altuvia S., Margalit H., Biham O. Stochastic analysis of the SOS response in Escherichia coli. PLoS One 2009, 4:e5363.
23. Adikesavan A.K., Katsonis P., Marciano D.C., Lua R., Herman C., Lichtarge O. Separation of recombination and SOS response in Escherichia coli RecA suggests LexA interaction sites. PLoS Genet. 2011, 7:e1002244.
24. Salehi T.Z., Tonelli A., Mazza A., Staji H., Badagliacca P., Tamai I.A., Jamshidi R., Harel J., Lelli R., Masson L. Genetic characterization of Escherichia coli O157:H7 strains isolated from the one-humped camel (Camelus dromedarius) by using microarray DNA technology. Mol. Biotechnol. 2011.
25. DelCarlo M., Loeser R.F. Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-betaI. Am. J. Physiol. Cell Physiol. 2006, 290:C802-C811.
26. Gou N., Onnis-Hayden A., Gu A.Z. Mechanistic toxicity assessment of nanomaterials by whole-cell-array stress genes expression analysis. Environ. Sci. Technol. 2010, 44:5964-5970.
27. Cui Y., Zhao Y., Tian Y., Zhang W., Lu X., Jiang X. The molecular mechanism of action of bactericidal gold nanoparticles onEscherichia coli. Biomaterials 2012, 33:2327-2333.