-
2
-
-
0034711239
-
Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD
-
Bertolotto C, Maulon L, Filippa N, Baier G, and Auberger P. Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD. J Biol Chem 275: 37246-37250, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 37246-37250
-
-
Bertolotto, C.1
Maulon, L.2
Filippa, N.3
Baier, G.4
Auberger, P.5
-
3
-
-
0024460328
-
Induction and prevention of chondrocyte hypertrophy in culture
-
Bruckner P, Horler I, Mendler M, Houze Y, Winterhalter KH, Eich-Bender SG, and Spycher MA. Induction and prevention of chondrocyte hypertrophy in culture. J Cell Biol 109: 2537-2545, 1989.
-
(1989)
J Cell Biol
, vol.109
, pp. 2537-2545
-
-
Bruckner, P.1
Horler, I.2
Mendler, M.3
Houze, Y.4
Winterhalter, K.H.5
Eich-Bender, S.G.6
Spycher, M.A.7
-
4
-
-
0034731404
-
Phorbol ester-induced generation of reactive oxygen species is protein kinase Cβ-dependent and required for SAPK activation
-
Datta R, Yoshinaga K, Kaneki M, Pandey P, and Kufe D. Phorbol ester-induced generation of reactive oxygen species is protein kinase Cβ-dependent and required for SAPK activation. J Biol Chem 275: 41000-41003, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 41000-41003
-
-
Datta, R.1
Yoshinaga, K.2
Kaneki, M.3
Pandey, P.4
Kufe, D.5
-
5
-
-
0034177184
-
Protein kinase C-β contributes to NADPH oxidase activation in neutrophils
-
Dekker LV, Leitges M, Altschuler G, Mistry N, McDermott A, Roes J, and Segal AW. Protein kinase C-β contributes to NADPH oxidase activation in neutrophils. Biochem J 347: 285-289, 2000.
-
(2000)
Biochem J
, vol.347
, pp. 285-289
-
-
Dekker, L.V.1
Leitges, M.2
Altschuler, G.3
Mistry, N.4
McDermott, A.5
Roes, J.6
Segal, A.W.7
-
6
-
-
0347481187
-
Increased oxidative stress with aging reduces chondrocyte survival: Correlation with intracellular glutathione levels
-
Del Carlo M Jr and Loeser RF. Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels. Arthritis Rheum 48: 3419-3430, 2003.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3419-3430
-
-
Del Carlo Jr., M.1
Loeser, R.F.2
-
7
-
-
0036171665
-
Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species
-
Del Carlo M Jr and Loeser RF. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis Rheum 46: 394-403, 2002.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 394-403
-
-
Del Carlo Jr., M.1
Loeser, R.F.2
-
8
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T and Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247, 2000.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
9
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
Frisch SM and Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626, 1994.
-
(1994)
J Cell Biol
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
12
-
-
0034190297
-
Protein kinase C signaling and oxidative stress
-
Gopalakrishna R and Jaken S. Protein kinase C signaling and oxidative stress. Free Radic Biol Med 28: 1349-1361, 2000.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1349-1361
-
-
Gopalakrishna, R.1
Jaken, S.2
-
13
-
-
0037458619
-
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
-
Han D, Antunes F, Canali R, Rettori D, and Cadenas E. Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem 278: 5557-5563, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 5557-5563
-
-
Han, D.1
Antunes, F.2
Canali, R.3
Rettori, D.4
Cadenas, E.5
-
14
-
-
0141504018
-
The role of reactive oxygen species in homeostasis and degradation of cartilage
-
Henrotin YE, Bruckner P, and Pujol JP. The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 11: 747-755, 2003.
-
(2003)
Osteoarthritis Cartilage
, vol.11
, pp. 747-755
-
-
Henrotin, Y.E.1
Bruckner, P.2
Pujol, J.P.3
-
15
-
-
0027998559
-
Autocrine signals enable chondrocytes to survive in culture
-
Ishizaki Y, Burne JF, and Raff MC. Autocrine signals enable chondrocytes to survive in culture. J Cell Biol 126: 1069-1077, 1994.
-
(1994)
J Cell Biol
, vol.126
, pp. 1069-1077
-
-
Ishizaki, Y.1
Burne, J.F.2
Raff, M.C.3
-
16
-
-
0032496326
-
Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change
-
Kheradmand F, Werner E, Tremble P, Symons M, and Werb Z. Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science 280: 898-902, 1998.
-
(1998)
Science
, vol.280
, pp. 898-902
-
-
Kheradmand, F.1
Werner, E.2
Tremble, P.3
Symons, M.4
Werb, Z.5
-
17
-
-
0036086234
-
A role for PKC-δ and PI 3-kinase in TNF-α-mediated antiapoptotic signaling in the human neutrophil
-
Kilpatrick LE, Lee JY, Haines KM, Campbell DE, Sullivan KE, and Korchak HM. A role for PKC-δ and PI 3-kinase in TNF-α-mediated antiapoptotic signaling in the human neutrophil. Am J Physiol Cell Physiol 283: C48-C57, 2002.
-
(2002)
Am J Physiol Cell Physiol
, vol.283
-
-
Kilpatrick, L.E.1
Lee, J.Y.2
Haines, K.M.3
Campbell, D.E.4
Sullivan, K.E.5
Korchak, H.M.6
-
18
-
-
0032538457
-
- generation but not degranulation or adherence in differentiated HL60 cells
-
- generation but not degranulation or adherence in differentiated HL60 cells. J Biol Chem 273: 27292-27299, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 27292-27299
-
-
Korchak, H.M.1
Rossi, M.W.2
Kilpatrick, L.E.3
-
19
-
-
1642473148
-
Cell death in cartilage
-
Kuhn K, D'Lima DD, Hashimoto S, and Lotz M. Cell death in cartilage. Osteoarthritis Cartilage 12: 1-16, 2004.
-
(2004)
Osteoarthritis Cartilage
, vol.12
, pp. 1-16
-
-
Kuhn, K.1
D'Lima, D.D.2
Hashimoto, S.3
Lotz, M.4
-
20
-
-
0036153745
-
Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice
-
Kurz B, Jost B, and Schunke M. Dietary vitamins and selenium diminish the development of mechanically induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice. Osteoarthritis Cartilage 10: 119-126, 2002.
-
(2002)
Osteoarthritis Cartilage
, vol.10
, pp. 119-126
-
-
Kurz, B.1
Jost, B.2
Schunke, M.3
-
21
-
-
0347088927
-
Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression
-
Kurz B, Lemke A, Kehn M, Domm C, Patwari P, Frank EH, Grodzinsky AJ, and Schunke M. Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression. Arthritis Rheum 50: 123-130, 2004.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 123-130
-
-
Kurz, B.1
Lemke, A.2
Kehn, M.3
Domm, C.4
Patwari, P.5
Frank, E.H.6
Grodzinsky, A.J.7
Schunke, M.8
-
22
-
-
0035205986
-
1-integrin, and tumor necrosis factor-α are required for phorbol diester-induced apoptosis in human myeloid leukemia cells
-
1-integrin, and tumor necrosis factor-α are required for phorbol diester-induced apoptosis in human myeloid leukemia cells. Mol Carcinog 32: 195-205, 2001.
-
(2001)
Mol Carcinog
, vol.32
, pp. 195-205
-
-
Laouar, A.1
Glesne, D.2
Huberman, E.3
-
23
-
-
0033588007
-
A role for reactive oxygen species in endothelial cell anoikis
-
Li AE, Ito H, Rovira II, Kim KS, Takeda K, Yu ZY, Ferrans VJ, and Finkel T. A role for reactive oxygen species in endothelial cell anoikis. Circ Res 85: 304-310, 1999.
-
(1999)
Circ Res
, vol.85
, pp. 304-310
-
-
Li, A.E.1
Ito, H.2
Rovira, I.I.3
Kim, K.S.4
Takeda, K.5
Yu, Z.Y.6
Ferrans, V.J.7
Finkel, T.8
-
24
-
-
0033948430
-
Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro
-
Loeser RF and Shanker G. Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro. Arthritis Rheum 43: 1552-1559, 2000.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1552-1559
-
-
Loeser, R.F.1
Shanker, G.2
-
25
-
-
3242804373
-
Inhibition of mitochondrial bioenergetics: The effects on structure of mitochondria in the cell and on apoptosis
-
Lyamzaev KG, Izyumov DS, Avetisyan AV, Yang F, Pletjushkina OY, and Chernyak BV. Inhibition of mitochondrial bioenergetics: the effects on structure of mitochondria in the cell and on apoptosis. Acta Biochim Pol 51: 553-562, 2004.
-
(2004)
Acta Biochim Pol
, vol.51
, pp. 553-562
-
-
Lyamzaev, K.G.1
Izyumov, D.S.2
Avetisyan, A.V.3
Yang, F.4
Pletjushkina, O.Y.5
Chernyak, B.V.6
-
26
-
-
0034698182
-
Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
-
Majumder PK, Pandey P, Sun X, Cheng K, Datta R, Saxena S, Kharbanda S, and Kufe D. Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis. J Biol Chem 275: 21793-21796, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 21793-21796
-
-
Majumder, P.K.1
Pandey, P.2
Sun, X.3
Cheng, K.4
Datta, R.5
Saxena, S.6
Kharbanda, S.7
Kufe, D.8
-
28
-
-
0842280650
-
Chondrocyte death during murine osteoarthritis
-
Mistry D, Oue Y, Chambers MG, Kayser MV, and Mason RM. Chondrocyte death during murine osteoarthritis. Osteoarthritis Cartilage 12: 131-141, 2004.
-
(2004)
Osteoarthritis Cartilage
, vol.12
, pp. 131-141
-
-
Mistry, D.1
Oue, Y.2
Chambers, M.G.3
Kayser, M.V.4
Mason, R.M.5
-
29
-
-
0032513291
-
Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2
-
Monney L, Otter I, Olivier R, Ozer HL, Haas AL, Omura S, and Borner C. Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2. J Biol Chem 273: 6121-6131, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 6121-6131
-
-
Monney, L.1
Otter, I.2
Olivier, R.3
Ozer, H.L.4
Haas, A.L.5
Omura, S.6
Borner, C.7
-
30
-
-
0034725109
-
Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-α-induced apoptosis of rat mesangial cells
-
Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, and Kitamura M. Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-α-induced apoptosis of rat mesangial cells. J Biol Chem 275: 12684-12691, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 12684-12691
-
-
Moreno-Manzano, V.1
Ishikawa, Y.2
Lucio-Cazana, J.3
Kitamura, M.4
-
31
-
-
0029583775
-
The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules
-
Muir H. The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules. Bioessays 17: 1039-1048, 1995.
-
(1995)
Bioessays
, vol.17
, pp. 1039-1048
-
-
Muir, H.1
-
32
-
-
0033618911
-
Protein kinase Cα promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage
-
Okuda H, Adachi M, Miyazawa M, Hinoda Y, and Imai K. Protein kinase Cα promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage. Oncogene 18: 5604-5609, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 5604-5609
-
-
Okuda, H.1
Adachi, M.2
Miyazawa, M.3
Hinoda, Y.4
Imai, K.5
-
33
-
-
0032545372
-
Bcl-2 prevents caspase-independent cell death
-
Okuno S, Shimizu S, Ito T, Nomura M, Hamada E, Tsujimoto Y, and Matsuda H. Bcl-2 prevents caspase-independent cell death. J Biol Chem 273: 34272-34277, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 34272-34277
-
-
Okuno, S.1
Shimizu, S.2
Ito, T.3
Nomura, M.4
Hamada, E.5
Tsujimoto, Y.6
Matsuda, H.7
-
34
-
-
0030927686
-
Simultaneous in situ detection of apoptosis and necrosis in monolayer cultures by TUNEL and trypan blue staining
-
Perry SW, Epstein LG, and Gelbard HA. Simultaneous in situ detection of apoptosis and necrosis in monolayer cultures by TUNEL and trypan blue staining. Biotechniques 22: 1102-1106, 1997.
-
(1997)
Biotechniques
, vol.22
, pp. 1102-1106
-
-
Perry, S.W.1
Epstein, L.G.2
Gelbard, H.A.3
-
35
-
-
0029974266
-
Doppa induces cell death but not differentiation of U937 cells: Evidence for the involvement of PKC-β1 in the regulation of apoptosis
-
Pongracz J, Deacon EM, Johnson GD, Burnett D, and Lord JM. Doppa induces cell death but not differentiation of U937 cells: evidence for the involvement of PKC-β1 in the regulation of apoptosis. Leuk Res 20: 319-326, 1996.
-
(1996)
Leuk Res
, vol.20
, pp. 319-326
-
-
Pongracz, J.1
Deacon, E.M.2
Johnson, G.D.3
Burnett, D.4
Lord, J.M.5
-
36
-
-
0035983747
-
The α5β1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro
-
Pulai JI, Del Carlo M Jr, and Loeser RF. The α5β1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro. Arthritis Rheum 46: 1528-1535, 2002.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1528-1535
-
-
Pulai, J.I.1
Del Carlo Jr., M.2
Loeser, R.F.3
-
37
-
-
0034517792
-
Activation of PKC is sufficient to induce an apoptotic program in salivary gland acinar cells
-
Reyland ME, Barzen KA, Anderson SM, Quissell DO, and Matassa AA. Activation of PKC is sufficient to induce an apoptotic program in salivary gland acinar cells. Cell Death Differ 7: 1200-1209, 2000.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1200-1209
-
-
Reyland, M.E.1
Barzen, K.A.2
Anderson, S.M.3
Quissell, D.O.4
Matassa, A.A.5
-
38
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen GS and Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 91: 443-446, 1997.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
39
-
-
0029922989
-
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger
-
Szabo C, Day BJ, and Salzman AL. Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Lett 381: 82-86, 1996.
-
(1996)
FEBS Lett
, vol.381
, pp. 82-86
-
-
Szabo, C.1
Day, B.J.2
Salzman, A.L.3
-
40
-
-
0025336262
-
Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolites
-
Tschan T, Hoerler I, Houze Y, Winterhalter KH, Richter C, and Bruckner P. Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolites. J Cell Biol 111: 257-260, 1990.
-
(1990)
J Cell Biol
, vol.111
, pp. 257-260
-
-
Tschan, T.1
Hoerler, I.2
Houze, Y.3
Winterhalter, K.H.4
Richter, C.5
Bruckner, P.6
-
41
-
-
33646386115
-
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
-
Werner E and Werb Z. Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. J Cell Biol 15: 15, 2002.
-
(2002)
J Cell Biol
, vol.15
, pp. 15
-
-
Werner, E.1
Werb, Z.2
-
42
-
-
9444275970
-
Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains
-
Whiteman M, Armstrong JS, Cheung NS, Siau JL, Rose P, Schantz JT, Jones DP, and Halliwell B. Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains. FASEB J 18: 1395-1397, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1395-1397
-
-
Whiteman, M.1
Armstrong, J.S.2
Cheung, N.S.3
Siau, J.L.4
Rose, P.5
Schantz, J.T.6
Jones, D.P.7
Halliwell, B.8
-
43
-
-
0031572309
-
Apoptosis of chondrocytes in transgenic mice lacking collagen II
-
Yang C, Li SW, Helminen HJ, Khillan JS, Bao Y, and Prockop DJ. Apoptosis of chondrocytes in transgenic mice lacking collagen II. Exp Cell Res 235: 370-373, 1997.
-
(1997)
Exp Cell Res
, vol.235
, pp. 370-373
-
-
Yang, C.1
Li, S.W.2
Helminen, H.J.3
Khillan, J.S.4
Bao, Y.5
Prockop, D.J.6
-
44
-
-
0036718504
-
Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: Studies using myxothiazol
-
Young TA, Cunningham CC, and Bailey SM. Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol. Arch Biochem Biophys 405: 65-72, 2002.
-
(2002)
Arch Biochem Biophys
, vol.405
, pp. 65-72
-
-
Young, T.A.1
Cunningham, C.C.2
Bailey, S.M.3
-
45
-
-
0142072319
-
Accelerated, aging-dependent development of osteoarthritis in α1 integrin-deficient mice
-
Zemmyo M, Meharra EJ, Kuhn K, Creighton-Achermann L, and Lotz M. Accelerated, aging-dependent development of osteoarthritis in α1 integrin-deficient mice. Arthritis Rheum 48: 2873-2880, 2003.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2873-2880
-
-
Zemmyo, M.1
Meharra, E.J.2
Kuhn, K.3
Creighton-Achermann, L.4
Lotz, M.5
-
46
-
-
0028983407
-
The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression
-
Zhang Z, Vuori K, Reed JC, and Ruoslahti E. The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc Natl Acad Sci USA 92: 6161-6165, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6161-6165
-
-
Zhang, Z.1
Vuori, K.2
Reed, J.C.3
Ruoslahti, E.4
|