Kinetics and molecular docking studies of an anti-diabetic complication inhibitor fucosterol from edible brown algae Eisenia bicyclis and Ecklonia stolonifera

Chemico-Biological Interactions

Volumn 206, Issue 1, 2013, Pages 55-62

  Jung, Hyun Ah ^a   Islam, Md Nurul ^b   Lee, Chan Mi ^b   Oh, Sang Ho ^c   Lee, Sanghyuk ^c,d   Jung, Jee H ^e   Choi, Jae Sue ^b  

^a Chonbuk National University   (South Korea)

^b Pukyong National University   (South Korea)

^c Korean Bio Information Center (KOBIC)   (South Korea)

^d Ewha Womans University   (South Korea)

^e Pusan National University   (South Korea)

Author keywords

Aldose reductase; Diabetes mellitus; Diabetic complication; Enzyme kinetic; Fucosterol; Molecular docking

Indexed keywords

ALDEHYDE REDUCTASE; ALPHA GLUCOSIDASE; FUCOSTEROL; PROTEIN TYROSINE PHOSPHATASE 1B; QUERCETIN; URSOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; BROWN ALGA; CONTROLLED STUDY; DIABETES MELLITUS; DRUG STRUCTURE; ECKLONIA STOLONIFERA; EISENIA BICYCLIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HYDROPHOBICITY; MOLECULAR DOCKING; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

Β-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ADVANCED GLYCATION ENDPRODUCT; AGE; ALDOSE REDUCTASE; ALDOSE REDUCTASE INHIBITORS; AR; ARIS; DIABETES MELLITUS; DIABETIC COMPLICATION; ENZYME KINETIC; FUCOSTEROL; HRAR; HUMAN RECOMBINANT ALDOSE REDUCTASE; MOLECULAR DOCKING; NADPH; RAT LENS ALDOSE REDUCTASE; RLAR;

ALDEHYDE REDUCTASE; ALPHA-GLUCOSIDASES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; HYPOGLYCEMIC AGENTS; KINETICS; LENS, CRYSTALLINE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PLANTS, EDIBLE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; STIGMASTEROL; STRUCTURE-ACTIVITY RELATIONSHIP;

ECKLONIA STOLONIFERA; EISENIA BICYCLIS; PHAEOPHYCEAE; RATTUS;

EID: 84883722374     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.08.013     Document Type: Article

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