Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: Consequences for retinoid metabolism

Biochemical Journal

Volumn 373, Issue 3, 2003, Pages 973-979

  Crosas, Bernat ^a,b,c   Hyndman, David J ^b   Gallego, Oriol ^a   Martras, Sílvia ^a   Parés, Xavier ^a   Flynn, T Geoffrey ^b   Farrés, Jaume ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b QUEEN S UNIVERSITY   (Canada)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aldo keto reductase; Enzyme kinetics; Retinoic acid; Retinol; Tolrestat

Indexed keywords

ALDEHYDES; CARBOHYDRATES; ISOMERS; METABOLISM;

RETINAL BIOAVAILABILITY;

ENZYMES;

ALDEHYDE REDUCTASE; ALDO KETO REDUCTASE; ALITRETINOIN; BETA CAROTENE; ENZYME; HUMAN ALDOSE REDUCTASE; HUMAN SMALL INTESTINE ALDOSE REDUCTASE; ISOTRETINOIN; OXIDOREDUCTASE; RETINAL; RETINOIC ACID; RETINOID; TOLRESTAT; UNCLASSIFIED DRUG;

ARTICLE; BIOAVAILABILITY; DRUG ACTIVITY; DRUG METABOLISM; ENZYME KINETICS; PRIORITY JOURNAL; PRODUCTIVITY; REGULATORY MECHANISM; RETINA; SMALL INTESTINE;

ALCOHOL OXIDOREDUCTASES; ALDEHYDE REDUCTASE; ANIMALS; BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INTESTINE, SMALL; KINETICS; RETINOIDS; SWINE;

FELIS CATUS; SUS SCROFA;

EID: 0043069767     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021818     Document Type: Article

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