Monoisoamyl dimercaptosuccinic acid abrogates arsenic-induced developmental toxicity in human embryonic stem cell-derived embryoid bodies: Comparison with in vivo studies

Biochemical Pharmacology

Volumn 78, Issue 10, 2009, Pages 1340-1349

  Flora, S J S ^a   Mehta, Ashish ^b  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

^b RELIANCE LIFE SCIENCES PVT LTD   (India)

Author keywords

Developmental toxicity; Efficacy; Embryoid body; Gene expression; Human embryonic stem cells; MiADMSA; Sodium arsenite

Indexed keywords

ANTIDOTE; ARSENIC; ARSENITE SODIUM; MONOISOAMYL DIMERCAPTOSUCCINIC ACID; SUCCIMER DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARSENIC POISONING; ARTICLE; CLINICAL EFFECTIVENESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; CYTOTOXICITY; DEVELOPMENTAL DISORDER; DOWN REGULATION; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; EMBRYONIC STEM CELL; FEMALE; GENE EXPRESSION REGULATION; GERM LAYER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MORTALITY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SKELETON MALFORMATION;

ANIMALS; ARSENITES; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CHELATING AGENTS; CONGENITAL ABNORMALITIES; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; HUMANS; PREGNANCY; RATS; RATS, WISTAR; SODIUM COMPOUNDS; SUCCIMER; TOXICITY TESTS;

EID: 70349446488     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.07.003     Document Type: Article

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