-
1
-
-
79955703244
-
Regulatory T cells: history and perspective
-
doi:10.1007/978-1-61737-979-6_1
-
Sakaguchi S, (2011) Regulatory T cells: history and perspective. Methods Mol Biol 707: 3-17. doi:10.1007/978-1-61737-979-6_1. PubMed: 21287325.
-
(2011)
Methods Mol Biol
, vol.707
, pp. 3-17
-
-
Sakaguchi, S.1
-
2
-
-
46249101518
-
How regulatory T cells work
-
doi:10.1038/nri2343
-
Vignali DA, Collison LW, Workman CJ, (2008) How regulatory T cells work. Nat Rev Immunol 8: 523-532. doi:10.1038/nri2343. PubMed: 18566595.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 523-532
-
-
Vignali, D.A.1
Collison, L.W.2
Workman, C.J.3
-
3
-
-
0034077559
-
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
doi:10.1002/1521-4141(200006)30:6
-
Cederbom L, Hall H, Ivars F, (2000) CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 30: 1538-1543. doi:10.1002/1521-4141(200006)30:6. PubMed: 10898488.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
4
-
-
79955529454
-
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
-
doi:10.1126/science.1202947
-
Qureshi OS, Zheng Y, Nakamura K, Attridge K, Manzotti C, et al. (2011) Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science 332: 600-603. doi:10.1126/science.1202947. PubMed: 21474713.
-
(2011)
Science
, vol.332
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
-
5
-
-
77149142263
-
Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes
-
doi:10.1016/j.immuni.2009.11.015
-
Boissonnas A, Scholer-Dahirel A, Simon-Blancal V, Pace L, Valet F, et al. (2010) Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes. Immunity 32: 266-278. doi:10.1016/j.immuni.2009.11.015. PubMed: 20137985.
-
(2010)
Immunity
, vol.32
, pp. 266-278
-
-
Boissonnas, A.1
Scholer-Dahirel, A.2
Simon-Blancal, V.3
Pace, L.4
Valet, F.5
-
6
-
-
33645067654
-
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
-
doi:10.1084/jem.20050783
-
Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, et al. (2006) Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med 203: 505-511. doi:10.1084/jem.20050783. PubMed: 16533880.
-
(2006)
J Exp Med
, vol.203
, pp. 505-511
-
-
Tadokoro, C.E.1
Shakhar, G.2
Shen, S.3
Ding, Y.4
Lino, A.C.5
-
7
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
doi:10.1038/nrm1868
-
Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, et al. (2006) Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 7: 83-92. doi:10.1038/nrm1868. PubMed: 16311599.
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
-
8
-
-
84867767000
-
Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory
-
doi:10.1126/science.1227049
-
Pace L, Tempez A, Arnold-Schrauf C, Lemaitre F, Bousso P, et al. (2012) Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory. Science 338: 532-536. doi:10.1126/science.1227049. PubMed: 23112334.
-
(2012)
Science
, vol.338
, pp. 532-536
-
-
Pace, L.1
Tempez, A.2
Arnold-Schrauf, C.3
Lemaitre, F.4
Bousso, P.5
-
9
-
-
48249103057
-
Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
-
doi:10.1073/pnas.0711106105
-
Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S, (2008) Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci U S A 105: 10113-10118. doi:10.1073/pnas.0711106105. PubMed: 18635688.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10113-10118
-
-
Onishi, Y.1
Fehervari, Z.2
Yamaguchi, T.3
Sakaguchi, S.4
-
10
-
-
29144533904
-
CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells
-
doi:16339524
-
Marski M, Kandula S, Turner JR, Abraham C, (2005) CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. J Immunol 175: 7889-7897. PubMed: 16339524.
-
(2005)
J Immunol
, vol.175
, pp. 7889-7897
-
-
Marski, M.1
Kandula, S.2
Turner, J.R.3
Abraham, C.4
-
11
-
-
67349179096
-
LFA-1 is critical for regulatory T cell homeostasis and function
-
doi:10.1016/j.molimm.2009.04.004
-
Wohler J, Bullard D, Schoeb T, Barnum S, (2009) LFA-1 is critical for regulatory T cell homeostasis and function. Mol Immunol 46: 2424-2428. doi:10.1016/j.molimm.2009.04.004. PubMed: 19428111.
-
(2009)
Mol Immunol
, vol.46
, pp. 2424-2428
-
-
Wohler, J.1
Bullard, D.2
Schoeb, T.3
Barnum, S.4
-
12
-
-
64849088870
-
Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function
-
doi:10.4049/jimmunol.0803827
-
Tran DQ, Glass DD, Uzel G, Darnell DA, Spalding C, et al. (2009) Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function. J Immunol 182: 2929-2938. doi:10.4049/jimmunol.0803827. PubMed: 19234188.
-
(2009)
J Immunol
, vol.182
, pp. 2929-2938
-
-
Tran, D.Q.1
Glass, D.D.2
Uzel, G.3
Darnell, D.A.4
Spalding, C.5
-
13
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CRF, A FB, Kupfer H, Sciaky N, Kufper A, (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395: 82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.F.1
Kupfer, H.2
Sciaky, N.3
Kufper, A.4
-
14
-
-
55849090253
-
Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion
-
doi:10.1146/annurev.cellbio.24.110707.175226
-
Dustin ML, (2008) Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion. Annu Rev Cell Dev Biol 24: 577-596. doi:10.1146/annurev.cellbio.24.110707.175226. PubMed: 18598213.
-
(2008)
Annu Rev Cell Dev Biol
, vol.24
, pp. 577-596
-
-
Dustin, M.L.1
-
15
-
-
0033538574
-
The immunological synapse:A molecular Machine controlling T cell activation
-
doi:10.1126/science.285.5425.221
-
Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, et al. (1999) The immunological synapse:A molecular Machine controlling T cell activation. Science 285: 221-226. doi:10.1126/science.285.5425.221. PubMed: 10398592.
-
(1999)
Science
, vol.285
, pp. 221-226
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
-
16
-
-
34249013684
-
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse
-
doi:10.1016/j.cell.2007.03.037
-
Sims TN, Soos TJ, Xenias HS, Dubin-Thaler B, Hofman JM, et al. (2007) Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse. Cell 129: 773-785. doi:10.1016/j.cell.2007.03.037. PubMed: 17512410.
-
(2007)
Cell
, vol.129
, pp. 773-785
-
-
Sims, T.N.1
Soos, T.J.2
Xenias, H.S.3
Dubin-Thaler, B.4
Hofman, J.M.5
-
17
-
-
77951158406
-
Protein kinase C-theta mediates negative feedback on regulatory T cell function
-
doi:10.1126/science.1186068
-
Zanin-Zhorov A, Ding Y, Kumari S, Attur M, Hippen KL, et al. (2010) Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science 328: 372-376. doi:10.1126/science.1186068. PubMed: 20339032.
-
(2010)
Science
, vol.328
, pp. 372-376
-
-
Zanin-Zhorov, A.1
Ding, Y.2
Kumari, S.3
Attur, M.4
Hippen, K.L.5
-
18
-
-
0141865705
-
Talin binding to integrin beta tails: a final common step in integrin activation
-
doi:10.1126/science.1086652
-
Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, et al. (2003) Talin binding to integrin beta tails: a final common step in integrin activation. Science 302: 103-106. doi:10.1126/science.1086652. PubMed: 14526080.
-
(2003)
Science
, vol.302
, pp. 103-106
-
-
Tadokoro, S.1
Shattil, S.J.2
Eto, K.3
Tai, V.4
Liddington, R.C.5
-
19
-
-
83755196111
-
Contact-dependent T cell activation and T cell stopping require talin1
-
doi:10.4049/jimmunol.1102028
-
Wernimont SA, Wiemer AJ, Bennin DA, Monkley SJ, Ludwig T, et al. (2011) Contact-dependent T cell activation and T cell stopping require talin1. J Immunol 187: 6256-6267. doi:10.4049/jimmunol.1102028. PubMed: 22075696.
-
(2011)
J Immunol
, vol.187
, pp. 6256-6267
-
-
Wernimont, S.A.1
Wiemer, A.J.2
Bennin, D.A.3
Monkley, S.J.4
Ludwig, T.5
-
20
-
-
33747623042
-
Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
-
doi:10.1038/ni1374
-
Katagiri K, Imamura M, Kinashi T, (2006) Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion. Nat Immunol 7: 919-928. doi:10.1038/ni1374. PubMed: 16892067.
-
(2006)
Nat Immunol
, vol.7
, pp. 919-928
-
-
Katagiri, K.1
Imamura, M.2
Kinashi, T.3
-
21
-
-
65649126736
-
Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes
-
doi:10.1038/emboj.2009.82
-
Katagiri K, Katakai T, Ebisuno Y, Ueda Y, Okada T, et al. (2009) Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. EMBO J 28: 1319-1331. doi:10.1038/emboj.2009.82. PubMed: 19339990.
-
(2009)
EMBO J
, vol.28
, pp. 1319-1331
-
-
Katagiri, K.1
Katakai, T.2
Ebisuno, Y.3
Ueda, Y.4
Okada, T.5
-
22
-
-
70349313125
-
A cell-intrinsic role for Mst1 in regulating thymocyte egress
-
doi:10.4049/jimmunol.0900678
-
Dong Y, Du X, Ye J, Han M, Xu T, et al. (2009) A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol 183: 3865-3872. doi:10.4049/jimmunol.0900678. PubMed: 19692642.
-
(2009)
J Immunol
, vol.183
, pp. 3865-3872
-
-
Dong, Y.1
Du, X.2
Ye, J.3
Han, M.4
Xu, T.5
-
23
-
-
84861746032
-
The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes
-
doi:10.1084/jem.20111692
-
Mou F, Praskova M, Xia F, Van Buren D, Hock H, et al. (2012) The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes. J Exp Med 209: 741-759. doi:10.1084/jem.20111692. PubMed: 22412158.
-
(2012)
J Exp Med
, vol.209
, pp. 741-759
-
-
Mou, F.1
Praskova, M.2
Xia, F.3
Van Buren, D.4
Hock, H.5
-
24
-
-
84869446316
-
Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus
-
doi:10.1038/ncomms2105
-
Ueda Y, Katagiri K, Tomiyama T, Yasuda K, Habiro K, et al. (2012) Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus. Nat Commun 3: 1098. doi:10.1038/ncomms2105. PubMed: 23033074.
-
(2012)
Nat Commun
, vol.3
, pp. 1098
-
-
Ueda, Y.1
Katagiri, K.2
Tomiyama, T.3
Yasuda, K.4
Habiro, K.5
-
25
-
-
0031897801
-
Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements
-
doi:10.1046/j.1440-1711.1998.00709.x
-
Barnden MJ, Allison J, Heath WR, Carbone FR, (1998) Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 76: 34-40. doi:10.1046/j.1440-1711.1998.00709.x. PubMed: 9553774.
-
(1998)
Immunol Cell Biol
, vol.76
, pp. 34-40
-
-
Barnden, M.J.1
Allison, J.2
Heath, W.R.3
Carbone, F.R.4
-
26
-
-
50949094396
-
c-Rel is essential for the development of innate and T cell-induced colitis
-
doi:18523276
-
Wang Y, Rickman BH, Poutahidis T, Schlieper K, Jackson EA, et al. (2008) c-Rel is essential for the development of innate and T cell-induced colitis. J Immunol 180: 8118-8125. PubMed: 18523276.
-
(2008)
J Immunol
, vol.180
, pp. 8118-8125
-
-
Wang, Y.1
Rickman, B.H.2
Poutahidis, T.3
Schlieper, K.4
Jackson, E.A.5
-
27
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)
-
Shinkai Y, Rathbun G, Lam KP, Oltz EM, Stewart V, et al. (1992) RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D). J Rearrangement Cell 68: 855-867.
-
(1992)
J Rearrangement Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.P.3
Oltz, E.M.4
Stewart, V.5
-
28
-
-
0026481133
-
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
-
doi:10.1084/jem.176.6.1693
-
Inaba K, Inaba M, Romani N, Aya H, Deguchi M, et al. (1992) Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 176: 1693-1702. doi:10.1084/jem.176.6.1693. PubMed: 1460426.
-
(1992)
J Exp Med
, vol.176
, pp. 1693-1702
-
-
Inaba, K.1
Inaba, M.2
Romani, N.3
Aya, H.4
Deguchi, M.5
-
29
-
-
67649518924
-
CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation
-
doi:10.1002/eji.200838603
-
Sojka DK, Hughson A, Fowell DJ, (2009) CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation. Eur J Immunol 39: 1544-1551. doi:10.1002/eji.200838603. PubMed: 19462377.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1544-1551
-
-
Sojka, D.K.1
Hughson, A.2
Fowell, D.J.3
-
30
-
-
46449083601
-
Supported planar bilayers for study of the immunological synapse
-
Unit 18.13: Unit 1813. PubMed: 18432988
-
Dustin ML, Starr T, Varma R, Thomas VK, (2007) Supported planar bilayers for study of the immunological synapse. Curr Protoc Immunol Chapter 18Unit 18.13: Unit 1813. PubMed: 18432988.
-
(2007)
Curr Protoc Immunol Chapter
, vol.18
-
-
Dustin, M.L.1
Starr, T.2
Varma, R.3
Thomas, V.K.4
-
31
-
-
0037446531
-
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells
-
doi:12682220
-
Mottet C, Uhlig HH, Powrie F, (2003) Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J Immunol 170: 3939-3943. PubMed: 12682220.
-
(2003)
J Immunol
, vol.170
, pp. 3939-3943
-
-
Mottet, C.1
Uhlig, H.H.2
Powrie, F.3
-
32
-
-
0042490495
-
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
-
doi:10.1038/ni950
-
Katagiri K, Maeda A, Shimonaka M, Kinashi T, (2003) RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol 4: 741-748. doi:10.1038/ni950. PubMed: 12845325.
-
(2003)
Nat Immunol
, vol.4
, pp. 741-748
-
-
Katagiri, K.1
Maeda, A.2
Shimonaka, M.3
Kinashi, T.4
-
33
-
-
0037174639
-
Neural and immunological synaptic relations
-
doi:10.1126/science.1076386
-
Dustin ML, Colman DR, (2002) Neural and immunological synaptic relations. Science 298: 785-789. doi:10.1126/science.1076386. PubMed: 12399580.
-
(2002)
Science
, vol.298
, pp. 785-789
-
-
Dustin, M.L.1
Colman, D.R.2
-
34
-
-
79959332816
-
Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation
-
doi:10.1016/j.immuni.2011.05.012
-
Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakuma M, Ishihara C, et al. (2011) Dynein-driven transport of T cell receptor microclusters regulates immune synapse formation and T cell activation. Immunity 34: 919-931. doi:10.1016/j.immuni.2011.05.012. PubMed: 21703543.
-
(2011)
Immunity
, vol.34
, pp. 919-931
-
-
Hashimoto-Tane, A.1
Yokosuka, T.2
Sakata-Sogawa, K.3
Sakuma, M.4
Ishihara, C.5
-
35
-
-
67349114397
-
T cell antigen receptor signaling and immunological synapse stability require myosin IIA
-
doi:10.1038/nrg2603
-
Ilani T, Vasiliver-Shamis G, Vardhana S, Bretscher A, Dustin ML, (2009) T cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nat Immunol 10: 531-539. doi:10.1038/nrg2603. PubMed: 19349987.
-
(2009)
Nat Immunol
, vol.10
, pp. 531-539
-
-
Ilani, T.1
Vasiliver-Shamis, G.2
Vardhana, S.3
Bretscher, A.4
Dustin, M.L.5
-
36
-
-
84864139002
-
Integration of the movement of signaling microclusters with cellular motility in immunological synapses
-
doi:10.1038/ni.2364
-
Beemiller P, Jacobelli J, Krummel MF, (2012) Integration of the movement of signaling microclusters with cellular motility in immunological synapses. Nat Immunol 13: 787-795. doi:10.1038/ni.2364. PubMed: 22751140.
-
(2012)
Nat Immunol
, vol.13
, pp. 787-795
-
-
Beemiller, P.1
Jacobelli, J.2
Krummel, M.F.3
-
37
-
-
80055107954
-
Dock 8 deficiency impairs CD8 T cell survival and function in humans and mice
-
Randall KL, Chan SS, Ma CS, Fung I, Mei Y, et al. (2011). Dock 8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med 208: 2305-2320.
-
(2011)
J Exp Med
, vol.208
, pp. 2305-2320
-
-
Randall, K.L.1
Chan, S.S.2
Ma, C.S.3
Fung, I.4
Mei, Y.5
-
38
-
-
84861078339
-
Dock 8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses
-
Harada Y, Tanaka Y, Terasawa M, Pieczyk M, Habiro K, et al. (2012). Dock 8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. Blood 119: 4451-4461.
-
(2012)
Blood
, vol.119
, pp. 4451-4461
-
-
Harada, Y.1
Tanaka, Y.2
Terasawa, M.3
Pieczyk, M.4
Habiro, K.5
-
39
-
-
84859875061
-
MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naïveT cells survival
-
doi:10.1182/blood-2011-09-378364
-
Nehme NT, Pachlopnik Schmid J, Debeurme F, André-Schmutz I, Lim A, et al. (2012) MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naïveT cells survival. Blood 119: 3458-3468. doi:10.1182/blood-2011-09-378364. PubMed: 22174160.
-
(2012)
Blood
, vol.119
, pp. 3458-3468
-
-
Nehme, N.T.1
Pachlopnik Schmid, J.2
Debeurme, F.3
André-Schmutz, I.4
Lim, A.5
-
40
-
-
84859837132
-
The phenotype of human STK4 deficiency
-
doi:10.1182/blood-2011-09-378158
-
Abdollahpour H, Appaswamy G, Kotlarz D, Diestelhorst J, Beier R, et al. (2012) The phenotype of human STK4 deficiency. Blood 119: 3450-3457. doi:10.1182/blood-2011-09-378158. PubMed: 22294732.
-
(2012)
Blood
, vol.119
, pp. 3450-3457
-
-
Abdollahpour, H.1
Appaswamy, G.2
Kotlarz, D.3
Diestelhorst, J.4
Beier, R.5
|